KEGG   Tupaia chinensis (Chinese tree shrew): 102487603
Entry
102487603         CDS       T02978                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup01522  Endocrine resistance
tup04010  MAPK signaling pathway
tup04015  Rap1 signaling pathway
tup04068  FoxO signaling pathway
tup04071  Sphingolipid signaling pathway
tup04114  Oocyte meiosis
tup04148  Efferocytosis
tup04218  Cellular senescence
tup04261  Adrenergic signaling in cardiomyocytes
tup04370  VEGF signaling pathway
tup04380  Osteoclast differentiation
tup04517  IgSF CAM signaling
tup04550  Signaling pathways regulating pluripotency of stem cells
tup04611  Platelet activation
tup04613  Neutrophil extracellular trap formation
tup04620  Toll-like receptor signaling pathway
tup04621  NOD-like receptor signaling pathway
tup04622  RIG-I-like receptor signaling pathway
tup04625  C-type lectin receptor signaling pathway
tup04657  IL-17 signaling pathway
tup04658  Th1 and Th2 cell differentiation
tup04659  Th17 cell differentiation
tup04660  T cell receptor signaling pathway
tup04664  Fc epsilon RI signaling pathway
tup04668  TNF signaling pathway
tup04670  Leukocyte transendothelial migration
tup04714  Thermogenesis
tup04722  Neurotrophin signaling pathway
tup04723  Retrograde endocannabinoid signaling
tup04728  Dopaminergic synapse
tup04750  Inflammatory mediator regulation of TRP channels
tup04912  GnRH signaling pathway
tup04914  Progesterone-mediated oocyte maturation
tup04917  Prolactin signaling pathway
tup04926  Relaxin signaling pathway
tup04932  Non-alcoholic fatty liver disease
tup04933  AGE-RAGE signaling pathway in diabetic complications
tup04935  Growth hormone synthesis, secretion and action
tup04936  Alcoholic liver disease
tup05014  Amyotrophic lateral sclerosis
tup05020  Prion disease
tup05022  Pathways of neurodegeneration - multiple diseases
tup05132  Salmonella infection
tup05133  Pertussis
tup05135  Yersinia infection
tup05140  Leishmaniasis
tup05142  Chagas disease
tup05145  Toxoplasmosis
tup05152  Tuberculosis
tup05161  Hepatitis B
tup05163  Human cytomegalovirus infection
tup05167  Kaposi sarcoma-associated herpesvirus infection
tup05169  Epstein-Barr virus infection
tup05170  Human immunodeficiency virus 1 infection
tup05171  Coronavirus disease - COVID-19
tup05205  Proteoglycans in cancer
tup05208  Chemical carcinogenesis - reactive oxygen species
tup05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tup05415  Diabetic cardiomyopathy
tup05417  Lipid and atherosclerosis
tup05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tup00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102487603 (MAPK11)
   04015 Rap1 signaling pathway
    102487603 (MAPK11)
   04370 VEGF signaling pathway
    102487603 (MAPK11)
   04668 TNF signaling pathway
    102487603 (MAPK11)
   04068 FoxO signaling pathway
    102487603 (MAPK11)
   04071 Sphingolipid signaling pathway
    102487603 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102487603 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102487603 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102487603 (MAPK11)
   04218 Cellular senescence
    102487603 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102487603 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102487603 (MAPK11)
   04613 Neutrophil extracellular trap formation
    102487603 (MAPK11)
   04620 Toll-like receptor signaling pathway
    102487603 (MAPK11)
   04621 NOD-like receptor signaling pathway
    102487603 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    102487603 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    102487603 (MAPK11)
   04660 T cell receptor signaling pathway
    102487603 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    102487603 (MAPK11)
   04659 Th17 cell differentiation
    102487603 (MAPK11)
   04657 IL-17 signaling pathway
    102487603 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    102487603 (MAPK11)
   04670 Leukocyte transendothelial migration
    102487603 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102487603 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    102487603 (MAPK11)
   04917 Prolactin signaling pathway
    102487603 (MAPK11)
   04926 Relaxin signaling pathway
    102487603 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    102487603 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102487603 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    102487603 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    102487603 (MAPK11)
   04722 Neurotrophin signaling pathway
    102487603 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102487603 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102487603 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    102487603 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102487603 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    102487603 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102487603 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102487603 (MAPK11)
   05161 Hepatitis B
    102487603 (MAPK11)
   05171 Coronavirus disease - COVID-19
    102487603 (MAPK11)
   05163 Human cytomegalovirus infection
    102487603 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102487603 (MAPK11)
   05169 Epstein-Barr virus infection
    102487603 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102487603 (MAPK11)
   05135 Yersinia infection
    102487603 (MAPK11)
   05133 Pertussis
    102487603 (MAPK11)
   05152 Tuberculosis
    102487603 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102487603 (MAPK11)
   05140 Leishmaniasis
    102487603 (MAPK11)
   05142 Chagas disease
    102487603 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102487603 (MAPK11)
   05020 Prion disease
    102487603 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    102487603 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102487603 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    102487603 (MAPK11)
   05415 Diabetic cardiomyopathy
    102487603 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102487603 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    102487603 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102487603 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102487603 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tup01001]
    102487603 (MAPK11)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102487603 (MAPK11)
Protein kinases [BR:tup01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102487603 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kdo Kinase-like FTA2
Other DBs
NCBI-GeneID: 102487603
NCBI-ProteinID: XP_006157643
LinkDB
Position
Un
AA seq 346 aa
MVRCAVGDPASCLLPPASWAESGEERDPKPCGWARSGAAARGALRVGRGPGRGSPRVPTP
LPNQVIGLLDVFTPATTLEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGL
KYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWM
HYSQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKMSSEHARTY
IQSLPPMPQKDLSSIFRGANPLAIDLLGKMLVLDSDQRISAAEALAHTYFSQYHDPDDEP
EAEPYDESVEAKERTVEEWKELTYQEVLSFKPPEPPQPPGSLEIEQ
NT seq 1041 nt   +upstreamnt  +downstreamnt
atggtcaggtgcgccgttggggacccagcctcctgcctcctgcctcctgcctcctgggcg
gagtcgggggaggagcgagacccgaaaccatgcgggtgggcgcgctccggggctgcggcc
cgtggggcgttgcgagtcggccgaggtccgggcagaggttccccgcgggtcccgactcct
ctccccaaccaggtcatcgggcttctggacgtcttcacgccggccacaaccctcgaggac
ttcagtgaagtgtacttggtgaccaccctaatgggcgccgacctgaacaacattgtcaag
tgccaggcgctaagtgacgagcatgtccagttcctggtttaccagctgctgcgaggcctg
aagtacatccactcggccgggatcatccaccgggatctgaagccgagcaacgtggctgtg
aatgaggactgtgagctcaggatcctggactttgggctggcacgccaggcggatgaggag
atgacggggtacgtggctacgcgctggtaccgggctcccgagatcatgctcaactggatg
cactacagccagacggtggacatctggtctgtgggctgcatcatggctgagctgctccag
ggaaaggccctctttccaggaaacgactacattgaccagctgaagcgcatcatggaggtg
gtgggcactcccagtcctgaggttctggcaaagatgtcctcagagcacgcccggacatac
atccagtccctgccccccatgccccaaaaggatctcagcagcatcttccgtggcgccaac
cccctggccatagaccttctggggaagatgcttgtgctggacagtgaccaaaggatcagt
gcggcggaggcactggcccacacctacttcagccagtaccatgacccggatgacgagcca
gaggcggagccctatgacgaaagcgtggaggccaaggagcgcacagtggaggagtggaaa
gagctcacctaccaggaagtcctcagcttcaagccccccgagccaccacagccacccggc
agcctggagattgagcagtga

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