Tupaia chinensis (Chinese tree shrew): 102488187
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Entry
102488187 CDS
T02978
Symbol
PDGFRA
Name
(RefSeq) platelet derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521
EGFR tyrosine kinase inhibitor resistance
tup04010
MAPK signaling pathway
tup04014
Ras signaling pathway
tup04015
Rap1 signaling pathway
tup04020
Calcium signaling pathway
tup04072
Phospholipase D signaling pathway
tup04144
Endocytosis
tup04151
PI3K-Akt signaling pathway
tup04510
Focal adhesion
tup04540
Gap junction
tup04630
JAK-STAT signaling pathway
tup04810
Regulation of actin cytoskeleton
tup05163
Human cytomegalovirus infection
tup05200
Pathways in cancer
tup05206
MicroRNAs in cancer
tup05214
Glioma
tup05215
Prostate cancer
tup05218
Melanoma
tup05230
Central carbon metabolism in cancer
tup05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102488187 (PDGFRA)
04014 Ras signaling pathway
102488187 (PDGFRA)
04015 Rap1 signaling pathway
102488187 (PDGFRA)
04630 JAK-STAT signaling pathway
102488187 (PDGFRA)
04020 Calcium signaling pathway
102488187 (PDGFRA)
04072 Phospholipase D signaling pathway
102488187 (PDGFRA)
04151 PI3K-Akt signaling pathway
102488187 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102488187 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102488187 (PDGFRA)
04540 Gap junction
102488187 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102488187 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102488187 (PDGFRA)
05206 MicroRNAs in cancer
102488187 (PDGFRA)
05230 Central carbon metabolism in cancer
102488187 (PDGFRA)
05231 Choline metabolism in cancer
102488187 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
102488187 (PDGFRA)
05218 Melanoma
102488187 (PDGFRA)
05215 Prostate cancer
102488187 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
102488187 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102488187 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102488187 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tup04090
]
102488187 (PDGFRA)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102488187 (PDGFRA)
Protein kinases [BR:
tup01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
102488187 (PDGFRA)
CD molecules [BR:
tup04090
]
Proteins
102488187 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
V-set
Herpes_gE
Motif
Other DBs
NCBI-GeneID:
102488187
NCBI-ProteinID:
XP_006143745
UniProt:
L9L577
LinkDB
All DBs
Position
Un
AA seq
1089 aa
AA seq
DB search
MGTSHPAFLVLGCLLTGPGLISCQLALPSILPNEHEKVVQLNSSFSLTCFGESEVSWRYP
VYEEESPDVDIRNEENNSGLFVSVLEVGHALAAHTGLYTCYYNHTQTDENELEGRDIYIH
VPDPDVAFVPLGMTDYFVVVEEDESVIIPCRTTDPDTVVTLRNSDGVVPASYDSKQGFNG
SFTDGPYTCEATVEGKTFQTIPFNVYTFQATAKLDLEMEVLKTVYKSGETIVLTCAVFNN
EVVDLQWIYPGKVKGRGSILLEEIKVPFIKLLYTLRIPEATVKDSGDYECAARHATRDVK
EMKKVTIAVHEKGFIEIKPTFSQLEAVNLHEVKHFVVDVWAYPSPRISWLKDNLTLIENL
TEITTDVEKIQEIRYQSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFQLLTQVPASILDV
VDDHHGSTGGQTVTCMAEGTPLPEIEWMVCKDIKKCNNETSWTVLANNASNVLMELHPQD
RSTVEGRVTFLKVEETVAVRCLAKNPLGAENRELKLVAPALRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLHPADESTRSY
VILSFENNGDYVDMRQAYTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKPALDAEVKD
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEMVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDLDHTYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDLDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDGMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatccagcattcctggtcctgggctgcctcctcacagggcctggcctc
atctcctgccagctcgcgctgccctccatccttcccaacgaacacgagaaggtcgtgcag
ctgaattcgtccttttctctgacgtgctttggggagagcgaagtgagctggcggtacccc
gtgtatgaagaagagagccccgacgtggacatcagaaacgaggaaaacaacagcggcctg
ttcgtgagcgtgctggaggtgggccatgccttggcagcccacacggggctgtacacctgc
tactacaaccacacgcagacggacgagaatgagctggaaggccgggacatctacatccac
gtgccagaccctgatgtagccttcgtccccctgggaatgaccgattatttcgttgtcgtg
gaggaggacgagtctgtcatcattccttgccgcacgacagaccccgacactgtcgtaacc
ctgcgcaacagtgacggcgtggtccctgcctcctatgacagcaagcagggctttaatggc
agcttcacagacgggccctacacctgcgaggccacggtcgaagggaagacgttccagacc
atcccgtttaacgtttatacctttcaagcaacagcaaaactggatctagaaatggaagtt
cttaaaactgtgtacaagtcaggcgaaacgattgtcctcacctgcgctgtctttaacaac
gaggtggttgacctgcagtggatttaccccgggaaagtgaaaggcagaggcagcattctg
ctggaggaaatcaaagtcccattcatcaaattgctgtacacactgaggatccccgaggcc
accgtgaaagacagtggcgactacgagtgtgctgcccgacacgcgaccagggacgtcaaa
gagatgaagaaagtcaccatcgctgttcacgagaaaggcttcattgaaatcaaacccacc
ttcagccagctggaagctgtcaacctgcacgaggtcaagcacttcgtggtggacgtgtgg
gcctacccctctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
accgagatcaccactgacgtggagaagatccaggaaataaggtatcaaagcaaactcaag
ctgatccgtgcaaaggaggaagacagtgggcattacaccatcgtggtgcagaatgaagac
gacgtgaagagctacactttccaactcctgacccaggttcccgcctccattctggacgtg
gttgacgaccaccacggctctaccgggggacagacggtgacgtgcatggccgaagggact
cctctccctgaaatcgagtggatggtttgcaaggatattaagaaatgtaataacgaaact
tcctggacagttttggccaacaatgcctccaacgtcctcatggagctccacccccaagac
aggagtaccgtggagggccgagtgacgttcctcaaagtggaggagaccgttgcagtgcgg
tgcctggccaagaaccctcttggagctgagaaccgagagctaaagctggtggcgcctgcc
ctgcgttctgagctcacggtggcggccgcggtcctggtgctgttggtgattgtgatcatc
tccctcattgtcctggttgtcatttggaaacagaaaccgaggtatgagattcgctggcgg
gtcattgagtcaatcagccccgatggacatgaatatatttatgtggacccgatgcagctg
ccgtatgactccaggtgggagttcccgagagacggattagtgcttggtcgggtcttggga
tctggcgcgtttgggaaagtggtggaaggaacagcctatgggctgagccggtcacagcct
gtcatgaaagttgcggtgaagatgctgaaacccacagccagatccagtgaaaagcaagcg
ctcatgtctgaactgaagataatgacgcacctggggccacacttaaacattgtgaacctg
ctgggagcctgtaccaagtcaggccccatttacatcatcaccgagtactgcttctacgga
gatctagtcaactacttgcataagaacagggacagcttcctcagccgccacccggagaag
ccaaagaaagagctggacatttttggactgcaccctgctgacgagagcacacggagttac
gttatcttatctttcgaaaacaacggtgactacgtggacatgagacaagcgtatacgacg
cagtacgtccccatgctggagaggaaagaggtttctaagtattcggacatccagaggtct
ctgtacgatcgcccggcctcctataagaagaaacccgcattagatgctgaagtcaaagac
ctgctgtcggatgataactcggaaggccttactttgttggatttgttgagcttcacctat
caagtggcccgaggcatggagtttttggcgtcaaaaaattgtgtccaccgggacctggct
gctcgcaatgttctcctggctcaaggaaaaattgtgaagatctgtgactttggcctggcc
agggacatcatgcatgattccaactacgtgtcgaaaggcagcaccttcctgcccgtgaag
tggatggctccggagagcatcttcgacaacctctacacaacgctgagcgacgtctggtcc
tacggcatcctgctctgggagatcttctccctcggtggcacgccctaccctggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcccgaccat
gccaccagtgaagtctacgagatcatggtcaagtgctggaacagtgagccagagaagaga
ccctccttctaccacctgagcgagatggtggagaatctgctgcccggacagtataaaaag
agttatgaaaaaattcacctggacttcctgaagagcgaccatccggccgtggcgcgcatg
cgcgtggacttggaccacacgtacatcggcgtcacctacaaaaacgaggaggacaagctg
aaggactgggaggggggcctggacgagcagaggctgagcgcagacagcggctacatcatc
cctctgccggacctcgacccggtgcccgaggaggaagacctgggcaagaggaatcgacac
agctcgcagacgtctgaagagagtgctattgagacaggctccagcagctcgaccttcatc
aagagggaggacgagaccattgaggacattgacgggatggacgacattggcatagactcc
tcagacctggtagaggacagcttcctgtaa
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