Tupaia chinensis (Chinese tree shrew): 102491971
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Entry
102491971 CDS
T02978
Symbol
ERN1
Name
(RefSeq) endoplasmic reticulum to nucleus signaling 1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup04140
Autophagy - animal
tup04141
Protein processing in endoplasmic reticulum
tup04210
Apoptosis
tup04932
Non-alcoholic fatty liver disease
tup05010
Alzheimer disease
tup05012
Parkinson disease
tup05014
Amyotrophic lateral sclerosis
tup05016
Huntington disease
tup05017
Spinocerebellar ataxia
tup05022
Pathways of neurodegeneration - multiple diseases
tup05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102491971 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102491971 (ERN1)
09143 Cell growth and death
04210 Apoptosis
102491971 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102491971 (ERN1)
05012 Parkinson disease
102491971 (ERN1)
05014 Amyotrophic lateral sclerosis
102491971 (ERN1)
05016 Huntington disease
102491971 (ERN1)
05017 Spinocerebellar ataxia
102491971 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
102491971 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102491971 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102491971 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102491971 (ERN1)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102491971 (ERN1)
Protein kinases [BR:
tup01001
]
Serine/threonine kinases: Other
IRE family
102491971 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
102491971
NCBI-ProteinID:
XP_006146895
LinkDB
All DBs
Position
Un
AA seq
966 aa
AA seq
DB search
MESAVSWRTGIGSSQTLGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQ
IPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQD
IWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYA
ASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKKVMHI
NVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEG
VAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPRLKEKHKLNYLRNHWLLIG
HHETPLSASTKMLERFPNNLPKHRENVIHAXKKSFEEVINLVDQAAKNAPTTVSQDVEEK
FARAPAKPEAPMDSMLKDMATIILSNSWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLL
QQQQLPFHPSGDTTQDAELLDTSGPYSESSGTSSPSTSPRASNHSGHSGSSISKAGTSPF
LEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADR
EVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPIALLQQ
TTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGV
PGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGAYS
LDRFHPEKHEDVIAQELIEKMIAMDPQKRPSATHVLKHPFFWSLEKQLQFFQDVSDRIEK
ESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHY
RELPADVRETLGSLPEDFVRYFTSRFPHLLSHTYRAMELCSHERLFQPYYCHEPPEPLPP
VVPDAL
NT seq
2901 nt
NT seq
+upstream
nt +downstream
nt
atggagtctgctgtctcctggaggactgggattggcagctctcagactttgggaagtaca
agcacagtgacgcttccagaaactttgctgtttgtgtcgaccctggatggaagtctgcat
gctgtcagcaagaggactggctcaatcaaatggactttaaaagaagacccagtcctgcag
atcccaacacatgtggaagagcctgccttcctcccagatcccaatgatggcagcttgtac
acacttggaggcaagaacaatgaaggcctgacaaaacttccttttaccatcccagagttg
gtgcaagcgtccccatgccggagttcagatggaatcctctacatgggcaaaaagcaggac
atctggtacgtcatcgacctcctgactggggagaagcagcagactttgtcctcggccttt
gcagatagtctctgcccgtccacttctcttctgtatctcgggcgaacagaatacaccatt
accatgtatgacaccaaaacccgtgagctccggtggaatgccacctactttgactacgca
gcctcgctgcccgaggacgacatggactacaagatgtcccactttgtgtccaatggcgat
gggctggtggtgactgtggacagtgaatccggggacgtcctgtggatccaaaactatgcg
tcccctgtggtggccttttatgtctggcagcgggagggtctgaagaaggtgatgcacatc
aacgtcgctgtggagaccctgcgctatctgaccttcatgtccggggaggtggggcgcatc
accaagtggaagtacccattccccaaggagacagaggccaagagcaagctgacgcccact
ctgtatgttgggaaatactcgaccagcctctatgcctctccttccatggtacacgagggg
gtcgccgtcgtgccacgcggcagcactctccccttgctagaaggcccccagaccgatggt
gtcaccattggggacaaaggggagtgtgtgatcacacctagcaccgacctcaagttcgac
cctagactcaaagagaagcacaagctcaactacttgaggaatcactggcttctgataggg
caccatgaaaccccgctctctgcatctaccaagatgttggagagatttcctaacaatctg
cccaaacaccgggaaaacgtgattcatgctnagaaaaagagctttgaggaggtcatcaac
ctggttgaccaggctgcgaaaaatgcacccaccaccgtgtcgcaggatgtggaagagaag
tttgctcgtgccccagccaagcccgaggcccccatggactccatgctcaaggacatggcc
accatcatcctgagcaacagctgggtggccttcatcatcacctaccccttgagcatgcat
cagcagcagcagctccagcaccagcagttccagaaggaactagagaaaattcagctcctg
caacagcagcagctgcccttccacccgtctggagacacgacccaggatgctgagctcctg
gacacatccggcccctactcggagagctcgggcaccagcagccccagcacgtctcccagg
gcctccaaccactctgggcactcgggcagctccatctccaaggctggcaccagccccttc
ctagagcaggatgacgaggatgaggaaaccagcatggtgatggtcgggaagatttcgttc
tgtcccaaggatgtcctgggtcatggcgctgagggcacgattgtgtaccggggcatgttt
gacaaccgcgacgtggccgtgaagaggatcctccctgagtgttttagctttgcagaccgg
gaagtccagctgctgcgagaatctgacgagcacccaaacgtgatccgttacttctgcaca
gagagggaccggcagttccagtacatcgccatcgagctgtgcgcagccacactgcaggag
tatgtggagcagaaggactttgcccacctcggcctggagcccatcgccttgctgcagcag
accacctcaggcctggcccacctccactccctcaacatcgttcacagagacttgaagccc
cacaacatcctcctctccatgcccaatgcgcacggcaggatcaaggccatgatctccgac
tttggcctctgcaagaagctggcagtgggcaggcacagcttcagccgccgttctggagtg
cccggcacagagggctggattgctccggagatgctgagcgaagactgcaaggagaacccc
acctacacagtggacatcttctctgcgggctgcgtcttttactacgtgatctccgaaggt
agccacccttttggcaagtccctgcagcgacaggccaacatcctcctgggtgcctacagc
cttgaccgcttccacccagagaagcacgaagacgtcattgcccaggaattaatagagaag
atgatcgcaatggatccccagaaacggccctcagcaacacacgtgctgaaacatccattc
ttctggagcctagaaaagcagctccaattctttcaggacgtgagcgaccgcatagaaaag
gagtccctggatggcccgatagtgaagcagctggagagaggtgggagagctgtggtgaag
atggactggagggagaacatcaccgtccccctgcagacagatctgcggaagttcagaacc
tacaagggtggctccgtccgagacctcctccgagccatgaggaataagaagcatcactac
cgggagctccccgcggacgtgcgggagacgctgggctccctgcccgaagacttcgtgcgc
tacttcacctcgcgcttcccccacctcctctcgcacacctaccgcgccatggagctgtgt
agccacgagagactcttccagccctactactgccatgagcccccagaacccctgccccca
gtggtgccggatgccctctga
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