Tupaia chinensis (Chinese tree shrew): 102492140 Help Entry 102492140         CDS       T02978                                  Symbol GCK Name (RefSeq) glucokinase   KO K12407   glucokinase [EC:2.7.1.2] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00010   Glycolysis / Gluconeogenesis tup00052   Galactose metabolism tup00500   Starch and sucrose metabolism tup00520   Amino sugar and nucleotide sugar metabolism tup00524   Neomycin, kanamycin and gentamicin biosynthesis tup01100   Metabolic pathways tup01200   Carbon metabolism tup01250   Biosynthesis of nucleotide sugars tup04910   Insulin signaling pathway tup04911   Insulin secretion tup04917   Prolactin signaling pathway tup04922   Glucagon signaling pathway tup04930   Type II diabetes mellitus tup04950   Maturity onset diabetes of the young tup05230   Central carbon metabolism in cancer Module tup_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate tup_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102492140 (GCK)    00052 Galactose metabolism     102492140 (GCK)    00500 Starch and sucrose metabolism     102492140 (GCK)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     102492140 (GCK)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     102492140 (GCK)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     102492140 (GCK)    04910 Insulin signaling pathway     102492140 (GCK)    04922 Glucagon signaling pathway     102492140 (GCK)    04917 Prolactin signaling pathway     102492140 (GCK)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     102492140 (GCK)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102492140 (GCK)    04950 Maturity onset diabetes of the young     102492140 (GCK) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.2  glucokinase      102492140 (GCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 SecA_SW Motif Other DBs NCBI-GeneID:  102492140 NCBI-ProteinID:  XP_006166077 UniProt:  L8YBQ4 LinkDB All DBs Position Un AA seq 467 aa AA seqDB search MASDHTAKNQPQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMARGLRLETHEEASVKML PTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTTHQMYSIPEDAMTGT AEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEG NNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHKCEVGMIVGTGCNACYMEEM QNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSANPGQQLYEKLIGGKYM GELVRLVLLKLVDENLLFHGEASDQLRTRGAFETRFVSQVESDSGDRKQIHNILSTLGLR PSAADCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPS FKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt atggcgtcagatcacacagcaaagaaccagccccagacagccttgactctggtggagcag atcctggcggagttccagctacaagaggaggacctgaagaaggtgatgaggcggatgcag aaggagatggcccgtggcctgaggctagagacccacgaggaggccagtgtgaagatgcta cccacctacgtgcgttccaccccggaaggctcagaagtcggcgactttctctccctggac ctgggcggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaggcaggccag tggagcgtgaagaccacgcaccagatgtactccatccccgaggacgccatgacgggcacc gctgagatgctcttcgactacatctctgagtgcatctctgacttcttggacaagcatcag atgaagcacaagaaactgcccctgggctttaccttttccttccccgtgaggcatgaggac atcgacaagggcatccttctcaactggaccaagggcttcaaggcctcaggagctgaaggg aacaacattgtggggcttctacgagatgccattaaaaggagaggggactttgagatggac gtggtggcaatggtgaacgacacagtagccacgatgatctcctgctactacgaagaccac aagtgtgaggtcggcatgattgtgggcactggctgcaacgcctgctacatggaggagatg cagaacgtggagctggtggagggcgacgagggccgcatgtgtgtcaatacggagtggggc gcctttggggactcgggcgagctggacgagttcctgctggagtacgaccgcgtggtggat gagaactccgcgaaccccggtcagcagctgtacgagaagctcatcggcggcaaatacatg ggcgagctggtacggctggtgctgctcaagcttgtggacgagaacctgctcttccatggg gaggcctcggaccagctgcgcacacgcggcgcattcgagacacgcttcgtgtcgcaggtg gagagcgactctggcgaccgcaagcagatccacaacatactgagcacgctggggctgcgg ccctccgctgccgactgcgacatcgtgcgccgcgcctgcgagagtgtgtccacgcgcgcc gcgcacatgtgctcggccgggctggcaggtgttatcaaccgcatgcgcgagagccgcagc gaggatgtgatgcgcatcacagtgggcgtggacggctcagtgtacaagctgcaccccagc ttcaaggagcggttccacgccagcgtgcgcaggctgacgcccagctgcgagatcaccttc attgagtcggaggaaggcagtggccggggtgcggccctggtctcagctgtggcctgcaaa aaggcctgcatgctgggccagtga

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