Tupaia chinensis (Chinese tree shrew): 102493152 Help Entry 102493152         CDS       T02978                                  Symbol RPS6KB1 Name (RefSeq) ribosomal protein S6 kinase B1   KO K04688   ribosomal protein S6 kinase beta [EC:2.7.11.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01521   EGFR tyrosine kinase inhibitor resistance tup01522   Endocrine resistance tup04012   ErbB signaling pathway tup04066   HIF-1 signaling pathway tup04140   Autophagy - animal tup04150   mTOR signaling pathway tup04151   PI3K-Akt signaling pathway tup04152   AMPK signaling pathway tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04350   TGF-beta signaling pathway tup04371   Apelin signaling pathway tup04666   Fc gamma R-mediated phagocytosis tup04714   Thermogenesis tup04910   Insulin signaling pathway tup04931   Insulin resistance tup05163   Human cytomegalovirus infection tup05165   Human papillomavirus infection tup05170   Human immunodeficiency virus 1 infection tup05200   Pathways in cancer tup05205   Proteoglycans in cancer tup05207   Chemical carcinogenesis - receptor activation tup05210   Colorectal cancer tup05212   Pancreatic cancer tup05221   Acute myeloid leukemia tup05224   Breast cancer tup05225   Hepatocellular carcinoma tup05226   Gastric cancer tup05231   Choline metabolism in cancer tup05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102493152 (RPS6KB1)    04350 TGF-beta signaling pathway     102493152 (RPS6KB1)    04371 Apelin signaling pathway     102493152 (RPS6KB1)    04066 HIF-1 signaling pathway     102493152 (RPS6KB1)    04151 PI3K-Akt signaling pathway     102493152 (RPS6KB1)    04152 AMPK signaling pathway     102493152 (RPS6KB1)    04150 mTOR signaling pathway     102493152 (RPS6KB1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102493152 (RPS6KB1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     102493152 (RPS6KB1)   09152 Endocrine system    04910 Insulin signaling pathway     102493152 (RPS6KB1)   09149 Aging    04211 Longevity regulating pathway     102493152 (RPS6KB1)    04213 Longevity regulating pathway - multiple species     102493152 (RPS6KB1)   09159 Environmental adaptation    04714 Thermogenesis     102493152 (RPS6KB1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102493152 (RPS6KB1)    05205 Proteoglycans in cancer     102493152 (RPS6KB1)    05207 Chemical carcinogenesis - receptor activation     102493152 (RPS6KB1)    05231 Choline metabolism in cancer     102493152 (RPS6KB1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102493152 (RPS6KB1)   09162 Cancer: specific types    05210 Colorectal cancer     102493152 (RPS6KB1)    05212 Pancreatic cancer     102493152 (RPS6KB1)    05225 Hepatocellular carcinoma     102493152 (RPS6KB1)    05226 Gastric cancer     102493152 (RPS6KB1)    05221 Acute myeloid leukemia     102493152 (RPS6KB1)    05224 Breast cancer     102493152 (RPS6KB1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102493152 (RPS6KB1)    05163 Human cytomegalovirus infection     102493152 (RPS6KB1)    05165 Human papillomavirus infection     102493152 (RPS6KB1)   09167 Endocrine and metabolic disease    04931 Insulin resistance     102493152 (RPS6KB1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102493152 (RPS6KB1)    01522 Endocrine resistance     102493152 (RPS6KB1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102493152 (RPS6KB1) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      102493152 (RPS6KB1) Protein kinases [BR:tup01001]  Serine/threonine kinases: AGC group   RSK family [OT]    102493152 (RPS6KB1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015 Motif Other DBs NCBI-GeneID:  102493152 NCBI-ProteinID:  XP_006154663 LinkDB All DBs Position Un AA seq 525 aa AA seqDB search MRRRRRRDGLYSAPDFQDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG IEQMDVTTSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL NT seq 1578 nt NT seq  +upstreamnt  +downstreamnt atgaggcgacgacggaggcgggacggcctttactcagcgccggacttccaagacagggaa gctgaggacatggcaggagtgtttgacatagacttggatcagccagaggacgcgggctct gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga ccatatgaacttggcatggaacattgtgagaaatttgaaatttcagaaactagtgtgaac agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtgcttggtaaaggg ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaatactgggaaaatattt gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat gcctttcagaccggtggaaaactctacctcatccttgagtatctcagtggaggagaatta tttatgcagttagaaagagagggaatatttatggaagacacagcctgcttttacttggca gaaatttccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaaccgactttggactatgc aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg gcccctgaaatcttgatgagaagtggtcacaatcgtgctgtggattggtggagtttggga gcattaatgtatgacatgctgactggagcacccccatttactggtgagaatagaaagaaa acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc agagatctgcttaaaaagctgctgaaaagaaacgctgcatctcgtcttggagctggtcct ggggatgctggagaagttcaagctcatccattcttcagacacattaactgggaagaactt ctagctcggaaagtggagcccccctttaagcctctgttgcaatctgaagaggatgtgagt cagtttgattcaaagtttacacgtcagacacctgtcgacagcccagatgactcaactctc agtgaaagtgccaaccaggtctttctgggttttacttatgtggctccatctgtacttgaa agcgtgaaagaaaagttttcctttgaaccaaaaatccgatcacctcgaagatttattggc agtccacgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt gcttcagccagcacggcaaatcctcagacacctgtagaatacccaatggaaacaagtgga atagagcagatggatgtgacgacaagtggggaagcgtcagcgccacttccaattcgacag ccgaactccgggccatacaaaaaacaagcttttcccatgatctccaaacggccagagcac ctgcgaatgaatctatga

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