Tupaia chinensis (Chinese tree shrew): 102493262 Help Entry 102493262         CDS       T02978                                  Symbol LRP2 Name (RefSeq) LDL receptor related protein 2   KO K06233   low density lipoprotein-related protein 2 Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup04340   Hedgehog signaling pathway tup04918   Thyroid hormone synthesis tup04979   Cholesterol metabolism Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04340 Hedgehog signaling pathway     102493262 (LRP2)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     102493262 (LRP2)   09154 Digestive system    04979 Cholesterol metabolism     102493262 (LRP2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:tup04131]     102493262 (LRP2) Membrane trafficking [BR:tup04131]  Endocytosis   Clathrin-mediated endocytosis    Low-density lipoprotein receptor (LDLR) family proteins     102493262 (LRP2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_a Ldl_recept_b FXa_inhibition cEGF DUF5050 EGF_CA SGL EGF Motif Other DBs NCBI-GeneID:  102493262 NCBI-ProteinID:  XP_014445283 LinkDB All DBs Position Un AA seq 4685 aa AA seqDB search MNGAGLRGRSFGARMQNASDTKHFKLLSSCLYVFYRKQKSKQEAKCDNQHFRCGNGHCIP SAWRCDGTKDCSDDSDEAGCSHSCQVGYFQCQSGGECIPTSWVCDYEQDCEDGSDEQQNC SGRTCSSDQITCSNGQCIPGEYRCDHVRDCADGTDERDCRYPACEQLTCASGACYNTSQK CDGKADCRDFSDEVNCSAVCMHNEFRCGSGECIPRSYVCDHASDCEDNSDEHSCNYQSCK GEQFTCPSGQCIHQNWVCDGENDCRDNGDEKGCESSSHHFHNCYPREWACPESGQCILIS KVCDGILDCPDGDDENSTTAGKYCGLTMCSALNCEYECHKTPGGGACVCPPGYIINKNDS RTCVAFDDCQIWGICDQKCENRGDHHQCLCEEGYILEHGRHCKANESSGKPSILFSNGWD LLIGDIHGRNFQFLAESQNRGVVVGIDFHYQLRKVFWTDTVQNKVFSVDVNNLKIQEIFN ISVDAPENLAVDWVSNKLYLVETKVSRIDMANLDGSYPVTLITEDLGHPRGIALDPTVGY LFFSDWASLSGEPKVERAFMDGSNRKVLVKTKLGWPSGITLDLASKRVYWLDCRFDYIET VTYDGIERKTVVSGGSLIPHPFEISLFEDTVFFTDWTMMSVMKANKFVDTNPQVYYHSSV RPYGVTVFHSLRQPYARNPCADNNGGCEQICVLSHRTDNGGLGYRCKCTFGFNLDTDERH CVAVEKFLLFSSQLAVRGIPFTFSTQEDVMVPVTGHLSFFVGIDFDAQENTIFFSDTSKD MIYKQKINGTGREILTANRVENVESLTFDWISKNLYWTDPTHKSISVMRLADKSRRAILN NLNSPRAIVVHPIAGYIFFTDWFRPAKIMRAWSDGSHLLPIVNTTLGWPNGLAIDWSALR LYWVDAFFNKIEHSTFDGVDRRKLDHIQQMTHPFGLTVFGEHVYFTDWRLGAIVQVRKRD GGDMTVIRRGIRNVMHVKSYDSSIQTGSNYCNRPVHPNGDCSHFCFPVPNFQRVCGCPYG MRLSSNQLTCEGDPAREPPTEQCGSFSFPCNNGRCVPSHYRCDGFDDCHDNSDEHLCGTS NTSCSSSSFTCAHGGQCIPARWRCDNHFDCMDESDEQNCPTRAPASCAESYFTCDNNVCI SRDWVCDTDNDCGDGSDEKNCKSGTCRPSQFQCSDHRCIDPLYVCDGDKDCADGSDEAGC VYNCTASQFKCANGEGCINNMYRCDGVFDCNDNSDEAGCPTRPPGMCHLDEFQCQGDGTC IPDTWECDGHPDCIQGSDEHHGCVPKTCPSSHFSCDNGHCIYKEWLCDGDNDCGDMSDEK DCPTQPFYCPSWQWQCPGLSICVNLSSVCDGVSDCPNGTDESPLCNQDSCSDANGGCTHE CIQGPFGAQCLCPEGYRLANDSKTCEDIDECAVLSFCSQHCYNTRGSFRCWCDKDYRLEG DGRTCKVTASESLLLLVANRNQIVADNITAQVHNIYPLVQNGSHIVAVDFDSISGRIFWS DSGQGKTWSAFQNGTDRRLVFDSSITMTETIAIDWIGRNLYWTDYATETIEVSTIDGSHR TVLISKNLTNPRGLALDPRMNEHVLFWTDWGRHPRIERASMDGSLRTVIVQEKIYWPTGL TIDYPNRLIYFMDSYLDFIDFCDYDGQHRRQVIASDLVIRHPYTLTLFEDSVYWTDRATH RVMQANKWHGGNRSVVMYNIHWALGLAAIHPAKQPNSTNPCASASCSHLCLLSSQGPKFY SCACSSGWSLSDDSVNCVRDEQPFLITVRRHTVYGISLDPEVKSSDAMVPITGIQNGFDA DFDDSEQFIYWVENAGEIHRVKTDGTNRTVLAPLSLLGSSMGLALDWISRNLYTTNPGTQ SIKVLTLRGDIRYGKTLITNDGTPLGAGSPIGIAVDPVRGKLYWSDQGTQSGVPAKIASA NMDGTDLKILFTGNFEHLEFITLDIKEQKLYWAVTSRGVIERGNVDGTERMILVHHLSHP WGIAVHDSFLYYCDEQYEVIERVDKATGANKVVLRDNVLNLRTLRIYHRRSIAEFSNGCS NNVNACEQICLPVPGGLFSCACATGFKLNPDNRTCSSYKSFIVVSMMSVVRGYSLEMSDH SEAMVPVAGQGRNALHVDVDVASGFIYWCDFSSSVASRNAIRRIKPDGSSFTNIITYGIG VNGVRGIAVDWLAGNLYFTNAFASETLIEVLRINTTYRRVLLKATVDMPRHIVVDPRNRY LFWADYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLAVDHSNDYIYWVDDSLDIIARIRF DGEGSQVIRYGSRYPTPYGITVFGNSIIWVDRNLKKIFKASKEPGNTEPPTVVRDNLNWL RDVTIFDEQVQPRSPTEVNNNPCLENNGGCSHLCFALPELHTPKCGCAYGTLESDGKSCA ISTENFLIFALDNSLRSLHLDPTDHSLPFQAITVERTAIAVVYDNINNRIYFTQNLDSEH GQISYVSLNSEIHSPTVIVSDIGTADGIAFDWINRRIYYSDYNNQTINSMAEDGSMRTVI ARVSKPRAIVLDPCRGFLYWTDWGTNAKIERATLGGNFRMPIVNSSLVWPSGLVLDHEDD LLYWADASLQKIERSSLTGTNREIIVSAVFHIFGLTLYDQYIYWTDFYTKKVYRANKYDG SGQIAMTTSMPVQPKGISTVVKNQQQQCSNPCDQFNGGCSHICVPGPNGVECQCPHEGHW YLANNNKYCIVDNGQRCNASFFTCLNGKCISKEWKCDNDDDCGDGSDELENVCAFHTCQP TAFTCANGRCVQYRYRCDYYDDCGDNSDEEGCLFAECNATTEFTCNNRRCIPLEFVCNGV NNCHDNETSDEKNCPDRTCQSGYTKCQNTNICIPRVYLCDGDNDCGDMSDESPTYCTAHT CSSSEFKCTSGRCIPQQWHCDQEADCPDGSDEPASCVHHEQTCLSDEFKCDSGRCISREW ICDGDNDCGDMSDEDERHHCEKRNCSRSEFFCINSRPPARRCIPLSWVCDGDADCSDAYD EHQNCTRRSCAENEFTCANGLCILNSFRCDWRNDCGDFSDERNCSYPTCHEHQFTCQNGR CINEAYVCDGQNDCGDDSDELSHLCHTPEATCPPHQFKCDNGHCIEMVKVCNHLDDCSDN SDEKGCGINECQDPSISGCDHNCTDTPTSFYCSCLPGYKLMSDKRTCVDIDECKETPFVC SQKCENVVGSYICKCAAGYIREPDGKTCRQNSNIEPYLIFSNRYYLRNLTVDGQFYSLIL QGLGNVVSLDFDRVEKRLYWIDIQRHVIERMFLNKTNREIIINHRLPAAEGLAVDWVARK LYWVDINLNSMFVSNLDGGYRRTLAQHCVDANNTFCFDNPRGIALHPQYGYVYWTDWGHR AYIARVGMDGTNKSVIISSKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGRHRHTVY DGTLSHPFAMTIFEDSVYWTDWNTRTVEKGNKYDGSDRTTLVNTTHRPFDIHVYHPYRQP IVSNPCGTNNGGCSHFCLIKAGGKGFTCECPDDFQTIQQNGNTYCQPMCSSTQFLCANNE KCIPIWWKCDGQRDCSDGSDEVALCPQRFCRLGEFQCKDGNCTKPQSICNAQKDCPDGSD EDHVLCENHRCEPNEWQCANKRCISDAWQCDTVDDCGDNSDEDSSHCASRTCQPGQFKCA NGRCIPQTWKCDVDDDCGDQSDEPLQECMSPAYRCDNHTEFSCKTNYRCVPWWAVCNGFD DCRDNSDEQGCEAMTCKSSGEFRCKNHHCIPLRWRCDRQDDCGDNSDEEDCVPRECTESE FRCANQQCIPSRWICDHDNDCGDNSDERDCEMRTCHPDYFQCTSGHCVPNRFKCDGIADC LDASDEASCPTRFPNGAYCPTTMFECKNHVCVQKFWQCDGDDDCGDGSDEELHLCLTVPC ESPQRFRCDNNRCIYSHKLCDGVDNCGDGSDEKKEHCRTPTSRPCTEGEFKCSNGNCISE QNVCDDVDDCGDGFDETGCNIGKERTCAENICEHNCTQLSEGGFICSCRSGFKAGILDRN SCYDINECEQFGVCPQKCHNTKGSYECSCADGFKSMSDHYGKRCAAEGSPPLLLLPDNVR IRKYNLSSEKFSDYLQDEEHIQAIDYDWDPQGIDLSIVYYTVLGQDSRFGAIKRAYIPNF ESGSNNLVQEVDLGLKYVMQPDGLAVDWVGRHIYWSDVKNQRIEVAKLDGRYRKWLITTQ LDQPSAIVVNPKLGLMYWTDWGKEPKIESAWMNGEYRKILVSENLGWPTGLSIDYLNNDR IYWSDFKEDVIETIKYDGTDRRIVLNEAMSPYSLDIFENQLYWISKEKGEVWKQDKFGQK EKEKVLVVNPWLTQVRIFHQLRYNQSVPNPCKQVCSHLCLLRPGGYSCACPQGSTFIQGS ATECDAAIEAPITMPLPCRCMHGGKCYFDENNLPKCKCSSGYTGPYCEIAFSKGMPPGTT AVAVLLTILLIIIIGALAIVGVFHYRKTGSLLPALPKLPSLSSLVKPSENGNGVTFRSGA DVNMDIGVSGFGPESVIDRSMAMNEDFAMEMGKQPVIFENPMYSARDNAVKVVLPAQIKT TQMSQVTVSGNVDNKNYGSPMSPSEIAPETTPHPPAADGTQAAKWNIFKRKPKKTTNFEN PIYAEMENEQKEGVAVAPPPSPSLPAKIPPQRDPTPAYTATEDTFKDTAHLVKEDSELPS QRFSL NT seq 14058 nt NT seq  +upstreamnt  +downstreamnt atgaatggagccggtctgcgtggccggagttttggggctcgaatgcagaacgcgtctgat acgaagcactttaaacttctttcaagttgtctttatgttttctatagaaaacagaagagc aagcaagaggcaaaatgtgacaatcagcattttcgctgtggaaatgggcactgtatccct tcagcctggaggtgtgatgggaccaaagactgctcggatgactctgatgaagctggctgc tctcattcctgccaggtgggctatttccagtgtcagagtggaggggaatgcatccctacg tcctgggtgtgtgactatgagcaagactgtgaagatggctcagatgaacaacagaactgc tctgggagaacatgctcaagtgatcagataacatgctccaatggccagtgtatcccgggc gaatacaggtgtgaccatgtcagagactgcgcggatggaactgacgagagagactgccgc tacccagcatgtgagcaacttacttgtgccagtggagcctgctataacactagtcagaag tgtgatgggaaagctgattgcagggacttttctgatgaagtcaactgtagtgcggtatgc atgcacaacgagtttcggtgtggcagtggagaatgtattcctcgctcttatgtctgtgac catgccagtgattgtgaagacaacagtgatgaacattcttgcaactatcagtcctgcaaa ggggaacagttcacttgtcccagtggccagtgcattcaccagaactgggtttgtgatgga gagaatgactgtagagataacggagacgaaaaaggatgtgaaagcagttctcatcatttt cataattgttacccaagggaatgggcttgtccagagtctggccaatgcatcttaatatct aaagtttgtgatgggattttggattgtccagatggagacgatgaaaacagtaccactgct ggaaaatattgtggtctgaccatgtgttctgctttgaactgtgagtatgaatgccataag acgccaggtggaggggcatgtgtatgcccccccggttatatcatcaacaagaatgacagc cgtacctgtgttgcatttgatgactgtcagatatggggaatttgtgaccagaagtgtgag aatcgaggtgaccatcaccagtgcctctgtgaggaaggctacatcctggagcacgggcgg cattgcaaagctaatgagtcctctggcaagccctccattctcttttccaatggttgggat ttgctaattggcgatattcatggaaggaacttccagttcctagcagagtctcaaaatcgt ggagtggttgtgggtatagattttcactatcagctgcggaaagtcttttggacagacact gtgcaaaataaggttttttcagttgacgtgaataacttaaaaatccaagaaattttcaat atttctgttgacgcgccagagaacctggctgtggactgggttagtaacaaactttatctg gtagagaccaaggtcagccgcatagatatggcaaatttggatggaagctatccggtgacc cttataactgaagacttggggcatcccagaggaattgccctggaccccactgttggttat ttatttttctcagattgggcgagcctttctggagaacctaaggtggaaagggctttcatg gacggcagcaaccgtaaagtcttggtcaaaacaaagctgggatggccttctgggataact ctggatctggcctcaaagcgtgtttactggcttgactgccgatttgattacattgaaact gtaacttatgatggaattgaaaggaagacagtggtcagtggaggctccctcattcctcat ccctttgaaataagtttgtttgaagacacagtgttttttactgactggacaatgatgtca gtgatgaaggcaaacaaatttgtggacaccaatccacaagtgtactaccattcttccgta aggccctatggagttactgttttccattccctcagacaaccttatgctagaaacccatgt gcagacaacaatgggggctgtgagcagatctgtgtcctcagccacagaacagataacggg ggtttgggttaccgctgcaagtgcacgttcggcttcaacctggatactgatgagcgccac tgcgtggctgttgagaagttcctgctcttttcatcgcaattggctgttcgtggtatcccc ttcaccttctctactcaggaagatgtgatggttccggtgacagggcatctttctttcttt gttgggatagattttgatgcccaggagaacactatctttttttcagatacatcaaaagac atgatttataaacaaaagatcaatggcacaggaagagaaattctcacagcaaacagagtg gaaaatgttgaaagtttgacttttgactggatttctaagaatctgtattggacagaccct actcacaagagtatcagtgtcatgaggcttgctgataaatcgagacgcgcaatactcaac aatttgaatagcccaagagcaattgtggttcaccctattgctgggtatatattcttcact gactggttccgtcctgctaaaattatgagagcatggagtgatgggtctcacctattgcct atcgtgaacactactcttggatggcccaatggattggccattgattggagtgctttacga ttgtactgggtcgatgccttttttaataaaattgagcacagcaccttcgatggtgtagac agaagaaaactcgatcatatacagcagatgacacatccctttggactcactgtctttgga gaacatgtctattttacggactggcgactgggtgctattgttcaagtcaggaaaagagat ggcggtgatatgacagttatccgaagaggcatccgtaacgtaatgcatgtgaaatcatat gacagcagcatacagaccggtagtaactactgcaatcgacccgtccatcctaatggcgat tgtagtcacttctgcttcccagtgccaaatttccagcgggtctgtgggtgcccctatggc atgaggctgtcttccaaccagttgacatgtgagggagacccagcccgtgaaccacccacg gaacagtgtggctccttttctttcccctgcaacaacggtagatgtgtgcccagtcactac cgatgcgatggcttcgatgactgtcatgataacagcgacgagcatctctgtgggacatct aatacttcctgttcatcttcgtccttcacctgtgcccatggaggacagtgtatccctgca agatggcgctgtgacaaccacttcgattgcatggatgagagtgacgaacagaactgccct acccgtgcacctgcttcttgcgctgaatcctactttacctgtgataataatgtgtgcatc tcaagagactgggtctgtgacacggacaatgattgtggggatggatctgatgaaaagaac tgcaaatcagggacctgccgacctagtcagtttcagtgctctgatcatcgatgcattgac ccattgtatgtgtgtgatggggacaaggactgtgcagatggatctgacgaggctggctgt gtgtataattgcactgcttctcaatttaagtgtgccaatggggaaggctgcattaacaac atgtatcgttgtgatggtgtttttgactgcaatgacaactctgacgaggcaggctgtcca accaggcctcccggtatgtgccacttggatgaatttcagtgccaaggagatggtacctgc atcccggatacctgggagtgtgatgggcatccagactgcatccagggatcggatgagcac catggctgtgtccccaagacctgcccatcttctcatttctcctgtgacaacggacactgc atctacaaagagtggctctgtgatggggacaatgactgcggtgacatgagcgatgagaag gactgccctactcagcccttttactgtcccagttggcagtggcagtgccctggccttagc atctgtgtgaatctgagttcagtgtgtgatggcgtctctgactgccccaatgggaccgat gagtccccactttgcaaccaggacagctgctcagatgctaatggtggctgtacacacgaa tgtattcaagggccctttggggctcagtgcctatgtcccgagggataccgacttgccaat gattctaaaacttgcgaagacatagatgaatgtgctgttctaagcttttgtagccagcac tgttacaataccagaggttctttccggtgctggtgtgataaagactacaggttagaaggt gacggaaggacttgcaaagttacagcatctgaaagtctgctgttacttgtggcaaatcgg aaccagattgttgcagacaatatcactgcccaggtccacaatatctatcccttggtccag aatggttctcacattgtagctgttgattttgattccatcagtggtcgtattttctggtct gattcaggtcagggtaaaacctggagcgcttttcaaaatggaacagacagaagattggta tttgacagtagtatcaccatgactgaaactatcgcaatagattggataggacgtaatctt tactggacagactatgctacggaaacaattgaagtctccacaattgatgggagccacagg accgtgctaattagtaaaaacctaacaaatcccaggggactagcattagatccaagaatg aatgagcatgtactattctggactgactggggccgtcaccctcgtattgagcgagccagc atggatggcagcttgcgcactgtcattgtccaagagaagatctactggcccactggctta actatcgactaccccaacagactaatttactttatggattcctaccttgatttcatagac ttttgtgattatgatggacagcatcggcggcaggtgatagccagtgacttggttatacgg catccctatacactaaccctcttcgaagattctgtatactggacggatcgtgcgactcat agggttatgcaagccaacaagtggcatggaggaaatcggtcagttgtgatgtacaatatt cactgggctctggggcttgcagccattcatcccgcgaaacaaccgaacagtacgaatccg tgtgcctctgcctcctgcagccatctttgcctgctctcctcgcagggacctaagttttat tcctgtgcctgttcttcaggatggagtctctctgatgattctgtgaattgtgtgagagat gaacaacctttcctaattactgtaagacgccatacggtttacggaatctcccttgatcct gaggtgaagagcagtgatgctatggttcccataacaggaatacagaatggctttgatgct gactttgatgactcagagcaattcatctattgggttgagaatgcaggtgaaattcacaga gtaaagacagatggcaccaacaggacagtgttagcccctctgtctctgttggggtcttct atgggcctggccttagactggatatcaagaaacctttataccaccaatcctggaactcag tcaatcaaggttttgacactccggggagatatcagatatggaaagacactgattaccaat gatgggacccctctgggagctggttctccaattggcatagctgttgatcctgttcgtggg aaactgtactggtcagaccaagggacacagagtggggttcctgccaaaattgcaagtgca aacatggatggcacagatttaaaaattctcttcactgggaacttcgaacatctggagttt atcactcttgacatcaaggagcagaaactctactgggcagtcaccagccgaggagtgatt gaaagaggaaatgtggatggtacagagcgaatgatcctggtacaccatctttcccacccc tggggaatcgctgtccatgattccttcctgtattactgtgatgaacagtatgaggtcatt gaaagagttgacaaggctactggggccaacaaagtcgttttgagagataatgttctcaat ctgaggacccttcgaatttatcacagacgcagcattgctgaattttcaaatggctgtagc aacaacgtgaatgcctgtgagcagatttgcctgcctgtaccaggaggattgttctcctgt gcctgtgccactggatttaaactcaatcctgataatcggacctgttcttcatataagtct ttcattgttgtttcgatgatgtctgtagtcagaggctatagcttggaaatgtcagatcat tcagaagccatggtgccagtggcaggccaaggacgaaatgcactgcatgtggatgttgat gtagcctctggctttatttattggtgtgactttagcagctctgtggcatctcgtaatgct atccgtagaattaaaccagatgggtcttcttttacaaacataattacatatggaattgga gtaaacggagtccgcggtattgcagtggactggctggcaggaaatctttatttcaccaat gcctttgcatctgaaactctgatagaagttctgcggatcaataccacttaccgccgtgtt ctccttaaagccacagtcgatatgcctcggcatattgttgtagaccccaggaacagatac ctcttctgggctgactatgggcaaaaaccaaagattgaacgatcgtttcttgactgtacc aatcgaactgtgcttgtatcagagggcatcgtcacaccacggggcttggcagtggaccat agcaatgactacatttattgggtcgatgattctttagatataattgcaaggatccgtttt gatggagagggatctcaagtgattcgttatggcagtcgttacccaactccttatggcatc actgtttttggaaattctattatatgggtagataggaatttaaaaaaaatcttcaaagct agcaaggaaccaggaaacacagagccaccaacagtggtaagagacaatctcaattggcta agagatgtgaccatctttgacgagcaggtccagcctcgatcaccaacagaggtgaacaac aacccttgtttggaaaataatggtggatgctcccatctctgttttgctctgcctgaattg cacaccccaaaatgtggctgtgcctatggaaccctggaaagtgatggcaagagctgtgcc atttcaacagaaaatttccttatctttgccttggataattccttgagaagtttacacttg gaccctacagaccatagtctgcctttccaagcaataactgtggaaagaactgccattgct gtggtctatgacaacataaataatagaatctacttcacacaaaatttagactctgaacat ggtcagatttcctatgtcagcctgaattcagagatccattctccaactgtcattgtttca gatatagggactgctgatggcattgcctttgactggatcaataggagaatttattacagt gactacaacaaccagacaattaattccatggctgaagatggttctatgcgcactgtgata gcccgcgtctcaaagccaagagcaattgtgttagacccctgccgcgggttcctgtactgg acagactggggaactaatgccaaaatcgagagagccacactgggaggaaatttccggatg cctattgtgaacagcagtctggtctggcccagtgggcttgttctggaccatgaggatgac cttctgtactgggcggatgctagtctgcagaagattgaacgcagcagtctaacaggcaca aatcgtgaaatcattgtcagcgcagtctttcatatttttggcttgactctctatgaccag tatatctactggacagacttttacaccaagaaagtttaccgagctaacaaatatgatggg tcaggtcagattgcaatgaccacaagtatgcctgtccagccaaagggcatctccactgtt gtgaagaaccagcaacagcagtgtagcaatccttgtgatcaatttaatgggggctgcagc catatctgtgtaccaggtccaaatggtgttgagtgccagtgtccccatgaaggtcattgg tatctggccaacaacaataagtactgcattgtggacaatggtcaacggtgtaacgcatcc tttttcacttgcctcaatgggaaatgcatctcgaaggagtggaaatgtgataatgacgat gactgtggtgatggcagcgatgagctggaaaatgtctgtgcattccacacctgccagccg acagccttcacctgtgccaatgggcgatgtgtccagtaccgttatcgctgtgattactat gacgactgcggtgacaacagtgatgaggaagggtgcctgtttgctgagtgcaatgccacc acggaattcacttgcaataatagaaggtgcatacctcttgagtttgtctgcaatggagtc aacaactgccatgataatgaaacttcagatgagaaaaattgccctgatcgcacgtgccag tctggatacacaaaatgtcagaatacaaacatttgcattcctcgtgtctatttatgtgat ggagacaacgactgtggagatatgagtgatgaaagccctacttactgcaccgctcacaca tgcagcagcagtgagttcaaatgcacctctgggcgttgtattcctcaacaatggcactgt gatcaagaagcagattgtcctgatggctctgatgagcctgcctcctgtgtacaccatgag caaacatgcctaagtgatgagttcaagtgtgatagtggaaggtgcatctcaagagaatgg atttgtgatggtgataatgattgtggggacatgagtgatgaggatgaaaggcaccattgt gagaaaaggaattgctcgagatctgagtttttctgtataaatagcagacctccagccagg aggtgcattcccttaagctgggtctgcgatggtgatgcagactgttctgatgcctacgat gaacatcagaattgtaccaggagatcttgtgctgaaaatgaattcacttgtgcaaacggg ctctgtatcctcaactcattcaggtgtgactggcgcaatgactgcggtgacttcagcgat gagaggaactgctcataccccacctgccatgagcatcagtttacctgtcagaatgggcgc tgcattaatgaggcctacgtctgtgatggacaaaatgactgtggagatgactctgatgag ctgagtcacctgtgccacaccccagaagccacatgcccacctcaccagttcaagtgtgac aatgggcactgtatcgagatggtaaaagtctgcaaccacctggatgattgctctgacaac agtgacgagaaaggctgtggcatcaacgagtgccaagacccttcaatcagtggttgtgat cacaactgcacagataccccaaccagtttctactgttcctgtcttcctggttacaagctt atgtctgacaagcggacttgtgttgatattgatgaatgcaaggaaacaccctttgtctgt agccaaaagtgtgagaatgtagtaggttcctacatctgtaagtgtgctgcaggctacatt cgagaaccagatggaaagacctgccggcagaacagtaacatcgagccctatctcattttc agcaaccgttactatctgagaaatctaactgtggatggccaattttactccctcattttg caaggcctaggcaatgttgtgtcattagattttgaccgggtagaaaagagattatactgg attgacatacagaggcatgtcattgagagaatgtttctgaataagacaaacagggagatt atcataaatcacagattaccagctgcagaaggtctggctgtagactgggttgccagaaaa ctttattgggtggatatcaacctgaattccatgtttgtctccaaccttgatggtggatac cgccgcactctggcccagcactgtgtggatgccaacaacacattctgctttgataatccc agaggaattgcccttcaccctcaatatgggtatgtctactggacagactggggtcaccgt gcatacattgcaagagtaggcatggatggaaccaataaatctgtgattatctcttccaag ttagagtggcccaatggcatcaccattgattacaccaatgatctactctactgggcagat gcacatcttggttacattgagtactctgatttggagggccgccatcgacacacagtgtat gatgggacgctgtctcacccctttgcgatgaccatttttgaagacagtgtttattggaca gattggaatacaaggacagttgaaaaaggaaacaaatatgatggatcagataggacgact ctggtgaacacaacacacagaccttttgacatccatgtgtatcatccatacaggcagccg attgtgagcaatccctgtggtaccaacaatggtggctgttctcatttctgcctcattaaa gcaggagggaaaggatttacctgtgagtgtccagatgacttccagaccattcaacagaat ggcaacacctactgccagcctatgtgctccagcactcagttcctgtgtgctaacaatgaa aagtgtattcctatctggtggaaatgtgatggacagagagactgctcggatggctctgat gaagtggccctgtgcccacagcgcttctgccggctaggagagttccagtgcaaggacggc aactgcaccaagccacagtccatatgcaatgctcagaaagattgtccggatgggtctgat gaagatcatgttctttgtgagaatcaccgctgtgaacccaatgaatggcagtgtgccaac aaacgttgcatctcagatgcctggcagtgtgacactgtagacgactgtggagataactca gacgaagacagttcccactgtgctagcaggacttgccagcctggccaatttaagtgtgcc aatggccgctgcatccctcagacctggaagtgtgatgtcgatgatgattgtggagaccag tcagatgagccactccaagaatgcatgagccctgcgtatcgttgtgacaaccacacggaa ttcagctgtaaaaccaactaccgctgcgtcccatggtgggctgtgtgcaatggttttgat gactgcagggacaacagtgatgagcaaggctgtgaggcaatgacatgcaaatcttcgggg gagttccgctgtaaaaatcaccactgcattcctcttcgctggaggtgtgataggcaggat gactgtggagataactcagatgaggaagactgtgttccccgggagtgcacagagagcgag tttcgatgtgccaatcagcagtgcattccctctcgatggatctgtgaccatgacaatgac tgtggggacaactcagatgagcgggactgtgagatgaggacctgccatcctgattatttt caatgtacaagtggacactgtgtgcccaaccgatttaaatgtgatggaatagctgactgt cttgatgcctctgatgaagcctcttgtcccactcggtttcccaatggtgcatactgcccc actactatgtttgaatgtaaaaaccacgtttgtgtccagaagttttggcagtgtgatggt gatgatgactgtggcgatggttctgatgaagaacttcacctatgcttgactgttccctgt gaatcaccacaacgtttccggtgtgacaataatcgctgtatttatagtcacaagctgtgt gatggtgtggataactgtggagatggaagcgacgagaagaaggagcactgtagaacacca acctctcggccatgtacagaaggtgaatttaagtgtagcaatggaaactgcatttcagag cagaatgtatgtgatgatgtcgatgactgtggtgatggttttgatgaaacgggctgcaat attggaaaagaacgaacatgtgctgaaaatatatgtgaacacaattgtacccaattaagt gaagggggatttatctgctcctgtagatctgggttcaaagctggtattttggacagaaac tcctgttatgatattaatgaatgtgagcagtttggggtttgtccccagaagtgccataac accaaaggaagttacgagtgttcctgtgctgatggcttcaagtctatgagtgaccactat gggaagcggtgtgcagctgaaggtagccctcctttgttgctactccctgacaatgttcga attcgaaaatacaatctgtcctctgagaagttctcagactaccttcaagatgaggaacat atccaagctattgattatgactgggatccgcagggcatagacctcagtattgtgtattac accgtgctagggcaggactccaggtttggtgctatcaaacgtgcctacatccccaacttt gaatccggcagcaataatcttgtgcaagaagttgacctgggcctgaaatatgtaatgcag ccagatggattagcagtggactgggttggaaggcatatttactggtcagatgtcaagaat caacggattgaggtggctaaacttgatggaagatataggaagtggttgattaccacccag ttggatcagccttctgcgattgttgtgaaccccaaactagggctcatgtactggactgac tggggaaaagaacctaaaatcgaatctgcctggatgaatggggagtatcgcaagatcctg gtttctgagaaccttggttggccaactggcctttctattgattatttgaacaatgaccga atatactggagtgacttcaaggaggatgttattgaaaccataaaatatgatggaactgat aggagaatcgttttaaatgaagctatgagcccttacagtctcgacatctttgaaaaccag ctatactggatatctaaggaaaagggagaagtatggaaacaagataaatttgggcagaaa gagaaagagaaagtgctggtagtgaacccttggctcacccaagtccgaatctttcaccaa ctcagatacaatcagtcagtgcctaacccttgtaaacaggtctgcagccacctctgcctc ctgagacctggaggatacagctgtgcctgtccccaaggctccacctttatacaggggagt gccactgagtgcgatgcagccatcgaagctcctatcaccatgcccctcccatgcaggtgt atgcacggaggaaaatgctattttgatgagaataacctccccaaatgcaagtgttctagt ggctacactgggccgtattgtgaaatcgcattttcaaaaggcatgcctccaggaacaaca gctgtggccgtgctgttgacaatccttttgatcatcatcatcggggctttggcaattgta ggagttttccactataggaaaactggctcccttttgcctgctctgcccaaactgccaagc ttaagcagtcttgtcaaaccctctgaaaatggaaatggagtgactttcagatcaggggca gacgtaaacatggatatcggagtgtctggttttgggcccgaatctgttattgacagatca atggcaatgaatgaggactttgcgatggagatggggaagcagcctgtgatatttgaaaac cccatgtattcagccagagacaacgctgtcaaagtggttctgccagctcagataaagacc acccagatgtcacaggtgacagtatctggaaatgtggataacaagaattatggaagtccc atgagcccttctgagatagctccagaaacaacgccgcaccccccagctgctgatggaacc caggcagcaaaatggaatatcttcaaacggaaaccaaaaaagaccaccaactttgagaat ccaatctatgctgagatggagaatgagcaaaaggaaggtgttgctgtggccccacctcca tcaccctctctccccgccaaaatccctccccaaagagatccaactccagcctatactgca acagaagacacttttaaagacactgcacatctcgttaaagaagactctgagctaccgagt caacgtttttctctgtaa

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