Tupaia chinensis (Chinese tree shrew): 102494629
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Entry
102494629 CDS
T02978
Symbol
SOS1
Name
(RefSeq) SOS Ras/Rac guanine nucleotide exchange factor 1
KO
K03099
son of sevenless
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521
EGFR tyrosine kinase inhibitor resistance
tup01522
Endocrine resistance
tup04010
MAPK signaling pathway
tup04012
ErbB signaling pathway
tup04014
Ras signaling pathway
tup04062
Chemokine signaling pathway
tup04068
FoxO signaling pathway
tup04072
Phospholipase D signaling pathway
tup04150
mTOR signaling pathway
tup04151
PI3K-Akt signaling pathway
tup04510
Focal adhesion
tup04540
Gap junction
tup04630
JAK-STAT signaling pathway
tup04650
Natural killer cell mediated cytotoxicity
tup04660
T cell receptor signaling pathway
tup04662
B cell receptor signaling pathway
tup04664
Fc epsilon RI signaling pathway
tup04714
Thermogenesis
tup04722
Neurotrophin signaling pathway
tup04810
Regulation of actin cytoskeleton
tup04910
Insulin signaling pathway
tup04912
GnRH signaling pathway
tup04915
Estrogen signaling pathway
tup04917
Prolactin signaling pathway
tup04926
Relaxin signaling pathway
tup04935
Growth hormone synthesis, secretion and action
tup05034
Alcoholism
tup05160
Hepatitis C
tup05161
Hepatitis B
tup05163
Human cytomegalovirus infection
tup05165
Human papillomavirus infection
tup05200
Pathways in cancer
tup05205
Proteoglycans in cancer
tup05206
MicroRNAs in cancer
tup05207
Chemical carcinogenesis - receptor activation
tup05208
Chemical carcinogenesis - reactive oxygen species
tup05210
Colorectal cancer
tup05211
Renal cell carcinoma
tup05213
Endometrial cancer
tup05214
Glioma
tup05215
Prostate cancer
tup05220
Chronic myeloid leukemia
tup05221
Acute myeloid leukemia
tup05223
Non-small cell lung cancer
tup05224
Breast cancer
tup05225
Hepatocellular carcinoma
tup05226
Gastric cancer
tup05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102494629 (SOS1)
04012 ErbB signaling pathway
102494629 (SOS1)
04014 Ras signaling pathway
102494629 (SOS1)
04630 JAK-STAT signaling pathway
102494629 (SOS1)
04068 FoxO signaling pathway
102494629 (SOS1)
04072 Phospholipase D signaling pathway
102494629 (SOS1)
04151 PI3K-Akt signaling pathway
102494629 (SOS1)
04150 mTOR signaling pathway
102494629 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102494629 (SOS1)
04540 Gap junction
102494629 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102494629 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102494629 (SOS1)
04660 T cell receptor signaling pathway
102494629 (SOS1)
04662 B cell receptor signaling pathway
102494629 (SOS1)
04664 Fc epsilon RI signaling pathway
102494629 (SOS1)
04062 Chemokine signaling pathway
102494629 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
102494629 (SOS1)
04912 GnRH signaling pathway
102494629 (SOS1)
04915 Estrogen signaling pathway
102494629 (SOS1)
04917 Prolactin signaling pathway
102494629 (SOS1)
04926 Relaxin signaling pathway
102494629 (SOS1)
04935 Growth hormone synthesis, secretion and action
102494629 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
102494629 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
102494629 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102494629 (SOS1)
05206 MicroRNAs in cancer
102494629 (SOS1)
05205 Proteoglycans in cancer
102494629 (SOS1)
05207 Chemical carcinogenesis - receptor activation
102494629 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
102494629 (SOS1)
05231 Choline metabolism in cancer
102494629 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
102494629 (SOS1)
05225 Hepatocellular carcinoma
102494629 (SOS1)
05226 Gastric cancer
102494629 (SOS1)
05214 Glioma
102494629 (SOS1)
05221 Acute myeloid leukemia
102494629 (SOS1)
05220 Chronic myeloid leukemia
102494629 (SOS1)
05211 Renal cell carcinoma
102494629 (SOS1)
05215 Prostate cancer
102494629 (SOS1)
05213 Endometrial cancer
102494629 (SOS1)
05224 Breast cancer
102494629 (SOS1)
05223 Non-small cell lung cancer
102494629 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
102494629 (SOS1)
05160 Hepatitis C
102494629 (SOS1)
05163 Human cytomegalovirus infection
102494629 (SOS1)
05165 Human papillomavirus infection
102494629 (SOS1)
09165 Substance dependence
05034 Alcoholism
102494629 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102494629 (SOS1)
01522 Endocrine resistance
102494629 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
102494629
NCBI-ProteinID:
XP_014444412
LinkDB
All DBs
Position
Un
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENILFEENIQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHVETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TRGTDEVPIPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHPVAGPPVPPRHSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
ggactgctggtgcctgcgctgaaaaaggtccaggggcaagttcatcctactcttgagtct
aatgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccacgaagtgcttcagatgtagaggaacgtgttcaaaaaagttttcctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcggaga
aaccctttatctctgccagtagaaaaaatccatcctttgttaaaggaggtcctaggttat
aaaattgaccatcaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaaactggtgggaaattatgtaagaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattaatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagaacaaact
tactatgatttggtaaaagcatttatggcagaaattcgacaatatataagggaactaaat
ctaattattaaggtttttagagagccctttgtctccaattcaaaattgttttctgctaat
gatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtgaagttactg
ggccatatagaagatactgtagagatgacagatgaaggcagtccccaccctttagtagga
agctgctttgaagacttagcagaggagcttgcatttgatccttacgaatcatatgctcga
gatattttacgacctggttttcatgatcgcttccttagtcagttatcaaagcctggggca
gcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
aggctacttctagcccctgtttaccactgtctccattattttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttaaaacaagcaataacagccttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcttgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagatattggacagtgt
tgcaatgagttcataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcacgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgaaaggtacaa
attaatgataaagatgacaccaatgaatacaagcatgcttttgaaataattttaaaagac
gaaaatagtgttatattttctgccaagtcagcggaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtaccctggaaaggatgcttgatgtaacaatgctacag
gaagagaaggaggagcagatgaggctgcctagtgctgatgtttatagatttgcagagcct
gactctgaagagaatattctgtttgaagagaacatacagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggcttacgtaccatatgtacgcagat
cctaattttgttcggacatttcttacaacatacaggtccttttgcaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagaaaatggagatcagcccttgagtgcggaactaaaaaggtttaggaaagaa
tatatacagcctgtacaactgcgggtattaaatgtctgtcggcactgggtagagcaccac
ttctatgattttgaaagagatgcagaccttttgcaacgaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccattactaagataatccaaaggaaa
aaaattgcaagagacaatggaccaggacacaatatcacatttcagagctctcctccaaca
gttgaatggcatataagcaggcctggccatgtagagacttttgacctgctcactttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctataccgagctgtccag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttttgaaaatgatccgacacaccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaatttagaagaaagagtagctgtggtgagtcgaataattgagattctccaa
gtctttcaggagttgaataacttcaatggtgttcttgaggttgtcagtgctatgaactca
tcacctgtttacagattagaccatacatttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattgagtgaagatcattataagaaatacttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctcactaatattttgaaaaca
gaagaaggcaaccctgaggtcctaaaaagacatggaaaagagcttataaacttcagcaag
aggaggaaagtggcagaaataactggagagatccagcagtaccaaaaccagccttactgt
ttacgagtagaatcagatatcaaaaggttcttcgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacagattaccttttcaacaaatccctcgaaatagagccacgaaat
cctaaacctctcccaagatttccaaaaaaatatagttatcccctaaaatctcccggtgtt
cgtccatcaaacccgagacctggtaccatgagacatcccacacctctgcagcaggagcca
agaaaaattagttacagtcggatccctgaaagtgaaacagagagtacagcctctgcaccc
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttccagtaccacagat
gtttgcagcgtgtttgattctgatcattcaagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaggggcactgatgaagtgcccatcccccctcctgttcctccacgaagacggccagaa
tctgccccagcggaatcttcgccatctaagattatgtctaagcatttggacagcccccca
gccattcctcctaggcaacccacatcaaaagcctattcaccacgatactcgatatcagac
cggacctctatctcagaccctcctgagagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctccagctcaccactacatctccagcctccccctctgggcaaa
aaaagtgaccatggcaatgccttcttcccaaacagcccttccccctttacaccacctcct
cctcaaacaccttctcctcatggcacgagaaggcacttgccatcaccaccattgacacag
gaagtggaccttcatccagttgctgggccgcctgttcctccacgacatagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcctcctga
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integrated database retrieval system
