Tupaia chinensis (Chinese tree shrew): 102495954 Help Entry 102495954         CDS       T02978                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01521   EGFR tyrosine kinase inhibitor resistance tup04010   MAPK signaling pathway tup04012   ErbB signaling pathway tup04014   Ras signaling pathway tup04015   Rap1 signaling pathway tup04020   Calcium signaling pathway tup04066   HIF-1 signaling pathway tup04070   Phosphatidylinositol signaling system tup04071   Sphingolipid signaling pathway tup04072   Phospholipase D signaling pathway tup04082   Neuroactive ligand signaling tup04150   mTOR signaling pathway tup04151   PI3K-Akt signaling pathway tup04261   Adrenergic signaling in cardiomyocytes tup04270   Vascular smooth muscle contraction tup04310   Wnt signaling pathway tup04360   Axon guidance tup04370   VEGF signaling pathway tup04510   Focal adhesion tup04517   IgSF CAM signaling tup04540   Gap junction tup04613   Neutrophil extracellular trap formation tup04650   Natural killer cell mediated cytotoxicity tup04664   Fc epsilon RI signaling pathway tup04666   Fc gamma R-mediated phagocytosis tup04670   Leukocyte transendothelial migration tup04713   Circadian entrainment tup04720   Long-term potentiation tup04723   Retrograde endocannabinoid signaling tup04724   Glutamatergic synapse tup04725   Cholinergic synapse tup04726   Serotonergic synapse tup04727   GABAergic synapse tup04728   Dopaminergic synapse tup04730   Long-term depression tup04750   Inflammatory mediator regulation of TRP channels tup04911   Insulin secretion tup04912   GnRH signaling pathway tup04916   Melanogenesis tup04918   Thyroid hormone synthesis tup04919   Thyroid hormone signaling pathway tup04921   Oxytocin signaling pathway tup04925   Aldosterone synthesis and secretion tup04926   Relaxin signaling pathway tup04928   Parathyroid hormone synthesis, secretion and action tup04929   GnRH secretion tup04933   AGE-RAGE signaling pathway in diabetic complications tup04935   Growth hormone synthesis, secretion and action tup04960   Aldosterone-regulated sodium reabsorption tup04961   Endocrine and other factor-regulated calcium reabsorption tup04970   Salivary secretion tup04971   Gastric acid secretion tup04972   Pancreatic secretion tup05017   Spinocerebellar ataxia tup05022   Pathways of neurodegeneration - multiple diseases tup05031   Amphetamine addiction tup05032   Morphine addiction tup05143   African trypanosomiasis tup05146   Amoebiasis tup05161   Hepatitis B tup05163   Human cytomegalovirus infection tup05164   Influenza A tup05170   Human immunodeficiency virus 1 infection tup05171   Coronavirus disease - COVID-19 tup05200   Pathways in cancer tup05205   Proteoglycans in cancer tup05206   MicroRNAs in cancer tup05207   Chemical carcinogenesis - receptor activation tup05214   Glioma tup05223   Non-small cell lung cancer tup05225   Hepatocellular carcinoma tup05231   Choline metabolism in cancer tup05415   Diabetic cardiomyopathy tup05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102495954 (PRKCA)    04012 ErbB signaling pathway     102495954 (PRKCA)    04014 Ras signaling pathway     102495954 (PRKCA)    04015 Rap1 signaling pathway     102495954 (PRKCA)    04310 Wnt signaling pathway     102495954 (PRKCA)    04370 VEGF signaling pathway     102495954 (PRKCA)    04066 HIF-1 signaling pathway     102495954 (PRKCA)    04020 Calcium signaling pathway     102495954 (PRKCA)    04070 Phosphatidylinositol signaling system     102495954 (PRKCA)    04072 Phospholipase D signaling pathway     102495954 (PRKCA)    04071 Sphingolipid signaling pathway     102495954 (PRKCA)    04151 PI3K-Akt signaling pathway     102495954 (PRKCA)    04150 mTOR signaling pathway     102495954 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102495954 (PRKCA)    04517 IgSF CAM signaling     102495954 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102495954 (PRKCA)    04540 Gap junction     102495954 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     102495954 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     102495954 (PRKCA)    04664 Fc epsilon RI signaling pathway     102495954 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     102495954 (PRKCA)    04670 Leukocyte transendothelial migration     102495954 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     102495954 (PRKCA)    04929 GnRH secretion     102495954 (PRKCA)    04912 GnRH signaling pathway     102495954 (PRKCA)    04921 Oxytocin signaling pathway     102495954 (PRKCA)    04926 Relaxin signaling pathway     102495954 (PRKCA)    04935 Growth hormone synthesis, secretion and action     102495954 (PRKCA)    04918 Thyroid hormone synthesis     102495954 (PRKCA)    04919 Thyroid hormone signaling pathway     102495954 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     102495954 (PRKCA)    04916 Melanogenesis     102495954 (PRKCA)    04925 Aldosterone synthesis and secretion     102495954 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102495954 (PRKCA)    04270 Vascular smooth muscle contraction     102495954 (PRKCA)   09154 Digestive system    04970 Salivary secretion     102495954 (PRKCA)    04971 Gastric acid secretion     102495954 (PRKCA)    04972 Pancreatic secretion     102495954 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102495954 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     102495954 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     102495954 (PRKCA)    04727 GABAergic synapse     102495954 (PRKCA)    04725 Cholinergic synapse     102495954 (PRKCA)    04728 Dopaminergic synapse     102495954 (PRKCA)    04726 Serotonergic synapse     102495954 (PRKCA)    04720 Long-term potentiation     102495954 (PRKCA)    04730 Long-term depression     102495954 (PRKCA)    04723 Retrograde endocannabinoid signaling     102495954 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102495954 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     102495954 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     102495954 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102495954 (PRKCA)    05206 MicroRNAs in cancer     102495954 (PRKCA)    05205 Proteoglycans in cancer     102495954 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     102495954 (PRKCA)    05231 Choline metabolism in cancer     102495954 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     102495954 (PRKCA)    05214 Glioma     102495954 (PRKCA)    05223 Non-small cell lung cancer     102495954 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102495954 (PRKCA)    05161 Hepatitis B     102495954 (PRKCA)    05171 Coronavirus disease - COVID-19     102495954 (PRKCA)    05164 Influenza A     102495954 (PRKCA)    05163 Human cytomegalovirus infection     102495954 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     102495954 (PRKCA)    05143 African trypanosomiasis     102495954 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     102495954 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     102495954 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     102495954 (PRKCA)    05032 Morphine addiction     102495954 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102495954 (PRKCA)    05415 Diabetic cardiomyopathy     102495954 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102495954 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102495954 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102495954 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:tup04131]     102495954 (PRKCA) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      102495954 (PRKCA) Protein kinases [BR:tup01001]  Serine/threonine kinases: AGC group   PKC family [OT]    102495954 (PRKCA) Membrane trafficking [BR:tup04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     102495954 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 Motif Other DBs NCBI-GeneID:  102495954 NCBI-ProteinID:  XP_006146824 LinkDB All DBs Position Un AA seq 672 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVSDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDDEGNAE LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgag tttgttacattttcttgtcctggtgcggataaggggcctgacactgacgaccccagaagc aagcacaagtttaaaatccacacttatggaagccccaccttctgcgatcactgtgggtca ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcgatatgaatgttcac aagcagtgtgtaataaacgtccccagcctctgtgggatggatcacacggagaagagggga cggatttacctgaaggccgaggtctccgatgaaaagctgcacgtcacagtacgagatgca aaaaacctaatccctatggatccaaatgggctttcagacccttacgtgaagctgaaactt atccccgatcccaagaatgaaagcaaacagaaaaccaaaaccatccgctccacactaaac ccccagtggaatgagtccttcaccttcaaattaaaaccttcagacaaagaccggcgactg tctgtagaaatttgggactgggatcgaactacaaggaatgatttcatgggatccctgtcc tttggagtgtcggagctaatgaagatgccagccagtggatggtacaagttgcttaaccag gaagaaggcgagtactacaacgtacccattccggaaggggacgacgaaggaaacgcggag ctcaggcagaagttcgagaaagccaagcttggcccggctggcaacaaagtcatcagccct tcagaagaccggaaacagccttccaacaacctggaccgagtgaaactcaccgacttcaat ttccttatggtgctggggaaggggagttttggaaaggtgatgctcgctgacaggaagggg accgaggaactgtatgcgatcaaaatcctgaagaaggacgtggtgattcaggatgacgac gtggagtgcaccatggtggagaagcgggtgctggccctgctggacaagccgccgttcctg acgcagctgcactcctgcttccagacggtggatcgcctgtactttgtcatggaatacgtc aacggcggggacctcatgtaccacattcagcaagtggggaagtttaaggagccacaggca gtattctatgcagcagagatttccatcggcttgttctttcttcataaaagaggaatcatt tatagggatctgaagttagataatgtcatgctggattcagaaggacacatcaaaattgct gacttcgggatgtgcaaggagcacatgatggacggagtcacaaccaggaccttctgtggg actccagactacatcgccccggagataatcgcttatcagccgtatggaaaatctgtggac tggtgggcctatggcgtcctgttgtatgagatgctagccgggcagcctccattcgacggc gaggatgaggatgagctgtttcagtctatcatggagcacaacgtctcctacccaaagtcc ctgtccaaggaggccgtgtccatctgcaaaggactgatgaccaaacacccggccaagcgg ctgggctgcggccccgagggcgagagggatgtacgagaacacgccttcttccggaggatc gactgggagaaactggagaaccgggagatccagccaccgttcaagcccaaagtgtgcggc aaaggagcggaaaacttcgacaagttcttcacacgagggcaacctgtcctaacgccgcct gatcagctggtcatcgctaacatagaccagtctgattttgaaggcttctcatatgtcaac ccccagttcgtgcaccccatcttacagagcgcagtatga

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