Tupaia chinensis (Chinese tree shrew): 102499923 Help Entry 102499923         CDS       T02978                                  Symbol TOP2A Name (RefSeq) topoisomerase (DNA) II alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:tup00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102499923 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:tup03032]     102499923 (TOP2A)    03036 Chromosome and associated proteins [BR:tup03036]     102499923 (TOP2A) Enzymes [BR:tup01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102499923 (TOP2A) DNA replication proteins [BR:tup03032]  Eukaryotic type   DNA Topoisomerases    102499923 (TOP2A) Chromosome and associated proteins [BR:tup03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102499923 (TOP2A)   Centrosome formation proteins    Centriole proteins     102499923 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102499923 NCBI-ProteinID:  XP_006156001 LinkDB All DBs Position Un AA seq 1519 aa AA seqDB search MQINKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVGLNY REVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKV EKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKRMFKQ TWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKD VKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCLTMSEKGFQQIS FVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPT FDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKH NRIKGIPKLDDANDAGGRSSAECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILN VREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGL LINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKSSTPNHKKWKVKY YKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTHFMEDR RQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFT CFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGT RLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLVNG AEGIGTGWSCKIPNFDVREVVNNIRRLMDGEELLPMLPSYKNFKGTIEELAPNQYVISGE VAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYKEYHTDTTVKFVVKM TEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGL RKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKE AQQKVPDEEENEESDNEKETEKTDSVTDSGPTFNYLLDMPLWYLTKEKKDELCKLRNEKE QELDTLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQIGLPGKGGKGKGKKTQVAEVLP SPRGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGSPQEDGVELEGLKQRIEKKQRREPGT KTKKQSTLPFKPIKKGKKKNPWSDSESDMSSNESNFDVPPRETEPRRAAAKTKFTMDLDS DDDFSDFDENSEDEDFVPSDASPPKTKTSQKHTNKESKPLKSTMSIVDLEVDDAKNSVPV SSSLPATDSPAETEIINPASKKNVTVKKTAAKSQSSTSTTGAQKRAAPKGTKRDPTLKSD ASQKPEPAKTKNRRKRKPSTSDDSDSNFEKIVSKAITSKKSKRENDDFHVDSAVSPRAKS GRSKKPIKYLEESDEDDLF NT seq 4560 nt NT seq  +upstreamnt  +downstreamnt atgcaaataaacaaaataaagaaaaatgaagatgcaaagaaaagactgtctattgaaaga atctatcaaaagaaaacccaactggaacatattttgctccgtccagacacctacattggc tctgtggaattggtgacccagcaaatgtgggtgtatgatgaagatgttggccttaattat agagaagtaacttttgttcctggtttatacaaaatatttgatgagattctagttaatgct gcggacaacaaacaaagggacccgaaaatgtcttgtatcagagtcacaattgacccggaa aacaatttaattagtatatggaataatggaaaaggtattcctgttgttgaacacaaagtt gagaagatgtatgtcccagctctcatatttggacaactcctaacttctagtaactatgat gatgatgaaaagaaagtaacaggtggtcgaaatggctatggagccaaattgtgtaacata ttcagtaccaaatttactgtggaaacagcctgcagagaatacaagagaatgttcaaacag acatggatggataacatggggagagctggtgaaatggaactcaagccttttaatggagaa gattatacatgtattaccttccagcctgatttatctaagtttaaaatgcaaagcctggac aaagatattgttgcactgatggttagaagagcatatgatattgctggatccactaaagat gtcaaagtctttcttaatggaaataagctaccagtaaaaggattccgtagttatgtggat atgtatttgaaggataagttagatgaaactggcaacccactgaaagtaattcacgaacaa gtaaaccacagatgggaagtatgtttgacaatgagtgaaaaaggctttcagcaaattagc tttgtcaatagcattgctacttccaagggtggcagacatgtcgactatgtagccgatcag attgtgactaaacttgttgatgttgtgaagaagaagaacaagggtggtgttgcagtgaaa gcacatcaggtgaaaaatcacatgtggatttttgtgaatgccttaattgaaaacccaacc tttgactctcagacaaaagaaaacatgactttacaagccaagagctttggatcaacatgc caattaagtgaaaaattcatcaaagctgcaattggctgtggtattgttgaaagtatacta aactgggtaaagtttaaggcccaagttcagttgaacaagaagtgttcagctgtaaaacat aacagaatcaaggggattcccaaactcgatgatgccaatgatgcagggggccgaagctcc gctgaatgtacgctcatcctgactgagggagactcagccaaaactttggctgtttcaggt cttggtgtggttggtagagataaatatggagttttccctcttagaggaaaaatactcaat gttcgagaagcttctcataaacagatcatggaaaatgccgaaattaacaatatcatcaag attgtgggtcttcagtacaagaaaaactatgaagatgaagattcattgaagactcttcgc tatgggaaaataatgattatgacagatcaggaccaagatggatcccatatcaaaggcttg ctgatcaattttatccatcacaactggccctctcttctgcgacatcgttttctggaggaa tttatcacccctattgtaaaggtctctaaaaacaagcaagaaatagctttctatagcctt cctgaatttgaagaatggaagagttctactccaaatcataaaaaatggaaagtcaagtat tacaaaggtttgggcaccagcacatcaaaagaagctaaagaatattttgcagatatgaaa agacatcgtatccaattcaaatattctggtcctgaagatgatgctgcaatcagcctggcc tttagcaaaaaacagatagatgatcgaaaagaatggttaactcatttcatggaagataga agacagcgaaagttacttggccttcctgaggattacttgtatgggcaaactaccacatat ctgacatacaatgatttcataaacaaggaacttatcctgttctcaaattctgataatgag agatctatcccatctatggtggatggtttgaaaccaggccagagaaaggttttgtttact tgtttcaagcggaatgacaagcgtgaggtgaaggttgcccagctagctgggtcagtggct gaaatgtcttcttatcatcatggtgagatgtcgctaatgatgaccattatcaatttggct cagaattttgtgggtagcaataatctaaacctcttgcaacccattggtcagtttggtacc agactacacggcggcaaggattctgccagccctcgctatatctttacaatgctcagtcct ttggctcggttattatttccaccaaaagatgatcacacattgaaattcttatacgatgac aaccagcgcgttgaacctgaatggtacattcctattatacccatggtgctggtaaatggc gctgaaggaatcggtactgggtggtcctgcaaaatccccaactttgatgttcgtgaagtt gtaaataatatcagacgtttgatggatggagaagaacttttgccaatgctgccaagttac aagaacttcaagggtactattgaagagctggctccaaatcaatacgtgattagtggtgaa gtagctattctaaattccacaaccattgaaatctcagagcttcccatcagaacatggacc cagacgtataaagaacaagttttagagcccatgttgaatggcactgagaagaccccccct ctcataacagactataaggaataccatactgataccactgtgaagtttgttgtgaagatg actgaagaaaaattggcagaggcagagagagttggactacacaaagtctttaaactccaa actagtctaacatgcaactctatggtgctttttgaccatgtaggctgtttaaagaaatat gacacagtgttggatattctacgagacttctttgaactcagacttaaatattatggatta agaaaagaatggcttctgggaatgcttggtgctgagtctgctaaactgaacaatcaggct cgctttattttagagaaaatagatggaaaaataatcattgaaaacaagcctaagaaagaa ttaattaaagttctaattcagaggggatacgattcagatcctgtgaaggcctggaaagaa gcccaacaaaaggttccagacgaagaagaaaatgaagagagtgacaatgaaaaagaaact gaaaagactgactctgtaacagattctgggccaaccttcaactaccttctcgatatgccc ctttggtatctaaccaaggaaaagaaagatgaattgtgcaaactaagaaatgaaaaagaa caagagctggacacattaaagagaaagagtccatcagatttgtggaaagaagacttggct gcttttattgaagaattggaggccgttgaagccaaagaaaaacaagatgaacaaatagga cttcctgggaaaggggggaaaggaaagggaaaaaaaacacaagtagctgaagttttacca tctccacgtggaaagagagtcattcctcgagtgaccatagagatgaaagcagaggcagaa aagaaaattaaaaagaaaattaagagtgaaaatactgaaggaagccctcaggaggatggt gtagaactagaaggcctaaaacaaagaatagagaagaagcaaagaagagagccaggtacc aagacaaagaaacaaagtacattgccatttaaaccaatcaaaaaaggaaagaagaaaaac ccctggtctgattcagagtcagatatgagtagtaatgaaagtaactttgatgtccctcca cgcgaaacagagccacggagagcagcagcaaaaaccaaattcacaatggatttggattca gatgatgatttctcagattttgatgaaaacagtgaggatgaagattttgtaccatccgat gctagtccacctaagaccaaaacttcccaaaagcatactaataaagaatcaaagccactg aaaagtaccatgtcaatagtggacctcgaggttgatgatgctaagaacagtgtaccagtt tcttcaagccttcctgctactgattcccctgctgaaactgaaattataaacccagcttct aaaaagaatgtgacagtgaagaagacagcagcaaaaagtcaatcttctacctccactact ggtgcccaaaaaagggctgctccaaaaggaaccaagagagatcccaccctgaagtctgat gcctctcaaaaacctgaacctgccaaaaccaagaatcgtcgcaaaaggaaaccatctact tctgatgattctgactcaaattttgagaaaattgtttctaaagcaatcacaagcaagaaa tccaagagggagaatgatgatttccatgtggactcagctgtgtctcctcgggcaaaatct ggacggtcaaagaaacctataaagtaccttgaagagtctgatgaagatgatctattttaa

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