Thermoproteus uzoniensis: TUZN_1001
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Entry
TUZN_1001 CDS
T01460
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tuz
Thermoproteus uzoniensis
Pathway
tuz00290
Valine, leucine and isoleucine biosynthesis
tuz00620
Pyruvate metabolism
tuz01100
Metabolic pathways
tuz01110
Biosynthesis of secondary metabolites
tuz01210
2-Oxocarboxylic acid metabolism
tuz01230
Biosynthesis of amino acids
Module
tuz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tuz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TUZN_1001
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TUZN_1001
Enzymes [BR:
tuz01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TUZN_1001
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
ComA
Motif
Other DBs
NCBI-ProteinID:
AEA12483
UniProt:
F2L687
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All DBs
Position
876377..878059
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AA seq
560 aa
AA seq
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MPEVCGHFCSKSPALYRPAAGNKTYISRQSGAYVGDRVEVLDTTLRDGAQGAAVSFTLED
KIRIALKLDEVGVDYIEGGWPYSNPKDREFFKAMKRYGLSRAKLAVFGSTRRRGVRPERD
ESLNSLVEADVPAAVIFGKSWTLHVREVLGATWEENLSMIAESVEYLKSHGMEVIYDAEH
FFQGYQEDPEMALASIEAAWRAGARVVVLADTNGGTPPHEIYRIVGEVKERFPAMPLGAH
MHNDIGCAVANTLMAVAAGARHVQGTINGIGERTGNADLTAVLPTLELKMGLKVLRDEPP
GVKFGRLREASRLVYEALGIQPNPYQPYVGDFAFAHKGGVHADAVMKVPRAYEHVDPALV
GNRRVIVVSEVAGGASLALKAAEELGLSLDKRSEAVRQALEEIKALEREGYSFDAAPASA
LLILMRRLGIHKERFKLLEWRVVTGPTSSAYAVVKVNIGGREVLEAGEGVGPVHAVDVAL
RRALTSAFPELQKTYLRDYRVVLPTAVKSTESIVRVTVEFSDGDRVWRTVGVSSNVVEAS
IKAIIDAYDFALQLDGLNLH
NT seq
1683 nt
NT seq
+upstream
nt +downstream
nt
gtgccggaggtatgtgggcatttctgttcaaaatcgccggctctatataggccggcggcc
ggaaacaaaacttatatatcgaggcaatctggggcatatgtcggggatcgggtcgaagtt
ctcgacacgacgttaagagacggggcgcagggcgccgccgtctccttcaccctcgaggac
aagataaggatcgccctaaagctcgacgaggtcggcgtcgactacatagaggggggctgg
ccctactcaaaccccaaggaccgcgagttcttcaaggccatgaagcgctacgggctgtcg
agggccaagctggccgtgttcggcagcaccaggcggaggggcgtcaggcctgagagggac
gagagcttgaactcgttggtggaggcagacgtgccggcggccgtgatattcggcaagagc
tggaccctccacgtgagggaggtgctgggcgccacttgggaggagaacttgtccatgatc
gcggagagtgtggagtatttgaagagccacggcatggaggttatatacgacgccgagcac
ttcttccaggggtaccaagaggatcccgagatggccctggcctctatagaggcggcttgg
agggccggcgcacgcgtcgtcgtgctcgccgacaccaacggcggcactccgccgcacgag
atctacagaatcgtcggcgaggtcaaggagaggttccccgcaatgcctctgggggcccac
atgcacaacgacatagggtgcgccgtcgccaacaccctcatggcggtggccgccggggcg
agacacgtgcaggggaccataaacggcattggtgagaggacaggcaacgcagacctgacc
gccgtgttgccgacgctggagctcaagatggggctgaaggtgctccgcgacgagcctccc
ggcgtcaagttcggcaggcttagggaggcctcgcggctggtctacgaggccttggggatc
cagccgaacccctaccagccctacgtcggcgacttcgccttcgcccacaagggaggggtc
cacgcagacgccgtcatgaaggtgccgagggcgtatgagcacgtcgacccggcgcttgtg
ggcaacagaagggtcatagtggtgtccgaagtcgccggaggggccagcctggccctcaag
gcggccgaggagctcggcctgtcgctcgacaagaggagcgaggcagtgaggcaggcgctg
gaggagataaaggcgttggagagggagggctactcctttgacgcggcgccggcctccgcc
ctcctcatattgatgaggcgcctcgggatccacaaggagaggttcaagctcctcgagtgg
agggtcgtgacgggcccgacgtcgtcggcgtacgcggtggtcaaggtcaacataggcggc
agagaggtcctcgaggcgggggagggcgtcggcccggtccacgccgtggacgtggccctg
cggcgcgccctcacgtcggcgttcccggagctgcagaagacctatctgagggactacaga
gtggttctgcccacggccgtgaagagcacggagagcatagtgcgggtgaccgtggagttc
tcggacggggatagggtgtggcggaccgtcggcgtgtcgagcaacgtggtggaggcctcc
ataaaggccataatagacgcctacgacttcgcgctccagctagacggcttgaatcttcat
taa
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