Tachysurus vachellii: 132843060 Help Entry 132843060         CDS       T09596                                  Symbol syne1a Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism tvc  Tachysurus vachellii Pathway tvc04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:tvc00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     132843060 (syne1a)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:tvc03036]     132843060 (syne1a) Chromosome and associated proteins [BR:tvc03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     132843060 (syne1a) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 KASH Spectrin_SYNE1_2 SR_desmoplakin_3 Spectrin_Anc-1 YibD_C Motif Other DBs NCBI-GeneID:  132843060 NCBI-ProteinID:  XP_060722108 LinkDB All DBs Position 3:complement(18470707..18586455) Genome browser AA seq 6807 aa AA seqDB search MCKDYQTLKYKLGSVVESAHAVIVAHSVQHNPEDMRRALTRLEAVKLELTGAQGDLDLFI CKSKSFISKLRNLPADLADAVRVELDTVVDQWMDTSERIETEANRLATVLELWNEVNSVV NDIECWSATSVSELNDGPVSLLSSANMEDCLSQFKVEIENKKLLMESLRVKVNELQEVTK NQQVDTELQVMAADLRKKIFHAEEVYEQACSILRDFSCQSRQLQDAISHMAEQLDTVENT LSELSQSSDPENVAKIKELRKILKQVDGGLDVTGESLRVLCRVYPAQQLTSVGESITQLV KRSEAAAHRSGQILRTLQKTLLHSFNELTQDFHSWLSELKSGTEETSEETGDLPRVPAQL QRLKVSLERIREGEEHLTRLHEEEEKLLTHLSESAAGRVQEHLASCHLALDKFIAACRQR VRCLEESAALQDRLEVCVDELRNWLRQMEESLKKEAVICGASQPGVPDCSTQLKRVEEIH KELLARRPSLERLYQSSLPLSKENSIPAELLSSHQALLQEAWTQLLHLQEYQAFGEALRA VGNWLEEVKGRLEKLESTEGNKEEVEERLERVQDILLMKGEGEVKLNMAAGKGELVIKSS GDAGQEVIRSKLQEVEDAWAALLLRAMSCHSRLEWTVSQWGLFVESQAQLRTWLEEVESE VKGPLEPQLGLREKRQQLDRLCLLLADVEDHQGALCYLEESAAELHKRTRDPAFKEEETA QLRAQFDDVRAAAEERVRLSEGVVFEHEKYMATVRELTDWLMSKGEELQRCSDPSGDSAS VERKLMEVRELVARGAREGRERLRRVRLSAESACRLTAATGCELMDSEVLALARALQQWE GQALRARDTLETAVTVATGAEREQRRLAEQLEEDTGRLERQLREWSDGLKRSERRNSGAD AVQGWTVAQGVLEGLQAAEVMEEKLKAQLNELCGFSSDLGAQSERVSALIKLHNSLSLRA ARECQNKEKLLEQRFRSSLRDFRQWLVNANISTAKCFDSPHSIQEASTSLQRIQEFLSDS EQGQDRLNAVISHGDRLAAVVSADRVEVVRSKANAAKDDWNNLMDNLKQRETVLQGLQCQ MQEFEVSVEPLQDWINRTEMSVQESSARLHDLPAKRLELSKLQSVLEEMGSMESELGMLR ERAHSLWEGQTAGKGFVHRVCQLAARYLALSNRTKEKVSRVERVVGEHQLFSQGLQELQS WVSEAQQILETCRSPNADKSVLLTRMSQLEELLAARQEREIQLKMLITRGEAVQRNTSAE GVPVVRKQIQDLKDSWDLLLSAAIQCKSQLEGALSHWTSYQEDVSQFEGWLERVDESLGN SDKHCTEMREKTANLRQAKLLYEEVLSHSSLLETIATKGSNLPEHSATQREVDELSTQYK TIKDKAKAAVKKAEALVLVHQEYQRGLHMFEDWLEQEQSNLALLSPLDGDVNALEKTLKE LHMLQSRCSEGHALLKSALSSREQVIPWGVPQIEDRALETAQREWQAYQDRLENTQASLE QTLIRLQQLEGCFQNLDRWLVDIELKVSLRSDRRAECAAKELQLQQLLQWEVEAVQKQGE MEALSALAQQVVEDSHVSARVSARVTQLTTRYHALLLRIQETIRQLQEELRSISEAQVAL RSFSDWMSLTTMGLKVASESKQAPDRASLEKKMKRLEALQRDVDEGHALFKTLREKAEQA VSFLDESGTCQLEKEVQESRSRLEELGLGIRAEHGATEKSAMLYKEFQERYKTQLQWMRD TRALLGSSAEPKAELYQRKAQLAKYKVLEQTLLSRDSALSAMMEKGKTLLSLLHSPSITE NMDRLQSEYQELCNTVRSRVQKLEAHVKKQEEYHTELQEVERWLLQMSSRMVTPDPTPGG GLEAAAQQLARHKAIMEEIAGFEERLAGLKERGDELMSGCTERLQARVRQQIQSHLQGAR DSYSAICSTAQRVYQSLDRELQRHVSLRDTLQQCQTWLFNIQEELQPPAQTPRYLEEALI QLKQERALQEQASTYLQLICSTCDLTEEKVQETAADIQQVKIQVEERMLESQELADSWRE IESLRSDLESHLREAEKFLQNMLRTPADLEPKVSQNQLDQAQDFIQEIQARQADLASLRE SIGRLVPSQDSPVLVEIGRLRRSWLELAKQAAELLEQREEDLQRSGDYQECLSMVEELFD QLSKEWDYLSRGDMESNAGCLDALKKLSIDLQDQRCVLEDLRDNKNAILPRLTLEDKDLV KEQVGYLEQRWTQMEVQVEQKIQDTIETLEDLNHLEDQLRETQEWAEVQRPSLSDVLKTS PPPDLAQSFLFDHLSFCAELEAKQQLINQSVSEAAILYAHLGLNEKRRLQTLVQDVQEAV ESLSSKAAHHRKSLNKVFTERTQFLQALDRAAAWIKQQEQRILADEHVALVPDELSKQVS ICKNICNSLRAYQVELTSLWTQGRELVKDATEDEKTETIQRLEELQGTFETSLQRCTNHL QHLERALVIRKYFKDDLDRICEWLRHAEAATFPIIDLNKNDAELQNQLAKYQQILDQTSA YENLLLIVQRAGQEVLPTLNEVDHCYLDEKLNGLPQQYNGILLSTKEKRDRIQRVILERR ELESLIEATRKALEELQEQCDALEKQSISGSLEDGERLHGDYDEIQTGLLNLFQAMNELK NKTQDFHCTGQPYTREVIDQLVSLYGRLDQETKEKVKQLNGTLNVLNDYRTTMAKMDSGI NAVREHMDELNSETQLDAMERLSKLHKMAKELDEITFYSEGLTGKIVECNQHFDHDTLRT QVSMKETQLQALKANIYKSIEECECCVGSKPSFQTKIKESLIWLKRVREDLRGLFTLQEI NVHVVQDEIRSTVTLQREIKSRLQLLKTLSQNERTSKQTFPSDMEICLKDIADLESEVQE SLTTKQAVLQSALSLLQMYQSALRTISQWFEDADAVIKQKNQNLELEDLTERLKELENVL TQEPTIKKAIQDIKGILPKMESFVYSGVVMKNKEALETTCQRSADVIEQLRSHQETLNRC SSQWTAFKKDREVLITELSEVEMKLAEFSTAKSSSLQEAEDKLRFHQDFVFQLEACQDKL SNLKEHSEQSDLNCMSGAAVCRSVCALDQRCTQLTSVAKVQEKALKDTVHDWRGFIEKLE KMRSVSEDLHSRVPDSVVEKAASTVALHNLLEYHDSFSREVERENSALTLLRHHALHLLL HSDTALLKTSNNQTSCISNQTTRLGKLSAMPLKPPYMTMKQKITPNKTPISTSNQSATPT TQPDTLSSQLTMPMTQPARPTTKSTTPNTQLTTPTTHSTTPTTHSSTPTTQPAIPNNHVD TPCNQTVTPSNHFEMSSTLTPKYQTIIPVNHLATPIKQAIKTNSEDAFCLREIQAMQEKY ESLLQKVCVSRQQVQVELLEREEVERELGLVKGWIQDTQGLLLSPTADLDTLLSDLEKAH GGVQSQRQALEQIADRQQMKYKDLHAAVPSEISTQLAQVTLALGSAEDQVQSREREVQHS RDVKEDFTARLKDIAEKVSTISVKLKQKGVDVEEAKEETETLREELEDCSHALSELDVAM QEFGEQNPLLARQLSTTLNKLTELHSQTSRLAEGRTSRLKKAEQHFEEFNERLTLILNWT EKAETLVSTSIVWSPASVMQEQIRTHQALLREWRRLQGEMEAVIERVGSLGEVVHTDALH QQVAELSRHAEELQQSTKTRLLNLQDAAKDLSRLESEVKSLHRSIERVQETLASPELARL SLREQLLQRQHLLTEMEGFKVQVQAVQKCMSTLQLPEDAMVTLPLCVTAQSLQQDSSHLQ HTTIQQCNILQEAVVQYEQYEQEVMNLQKMIEEAQRVIQDRPVTTGNIHELQTQIQHHEE LSQKIKGYQEQIAALNSKCKMLTLKAKHATMLLTVSEVGGLSDGLEELEDEEEEMVKHPT THPSVVMMTAGRCHTLLSPVTEESGEEGTNSEVSSPPACRSPSPGPNADISLNQVPGKAP LSRAPLQELYDQSMESAATANLDDLQRSWETLKNVISEKQKSLYEALERQQHYQESLQSI STKMESIEASLSEGLEPGKSPESQMAAHQALMDEILMLQDEISALQACFSEELQRDEESP EQDAGDQLALHSTLTVLGERMATIRMKASGKRQLLEECLNEQLEEQRQEQALQRYHSEAE ELDHWLLSTRATLNSALQPHPEDMDMEEQLIDCQNMLMEIEQKVLCLSELSVHSESLLLE GKAGTRGDAEQLTLKLHSLKASLLELQRILQDKHTHIQGSLMEQEESEPDSALTQSPSIL DWLSQARSTRSQQHQDTVQRQRELEAQLEEQRKLMQSVASRGEELLSHSHTTPTGDSAAN CQDMSDPGESTSLSTSGNEQGDMRMKWENLNKDLNTKLQFLFNTMQDEQLSSVYQRSRVS SPGSLFRGDQLTPDIFSPSALFENFNQKLEELAEADVKHAHTREKSLYEAVCSASTWLDG AENTLLSGPVLLSDDSEIQLFHLEGLNKEVKNVSEEVSKCQDVLEGRDGGGDGLIEEVLD GLDERLRLMDSLLEQRCDGIRDRLQEHTTFQVELRQLFTAMSDSKHQLLQKMCGAADRPA SRQLETLGEAEGSLREFEQRLCEMKTKGETLQSDPVITQELLRLQDMYEELVEMVGSKRS ALNQMLVLKVQYEKALQDLQELVDTAQDKMAADQKMTAGSVLEVQILLDKHKEFFQGLEA HVVLTQAFFRQVSVVMVQREVQVLEQTVAQAHTVLKQAHRRGVELEGILEEWSSFVGDYQ ALYKQLEVVESSIPVVGLVEETDERLSERIALYQCLKSTLVERQQQLYQVLEDGKRLLLR VCCSELETQLTQLGEHWLSSTTKISKELQRLDSTLKHWTRYQSESAELGQWLSSALDRLE FWSTQSVTVPQELETVRDHLYAFLEFSKEVDAKSSLRSSVLSRGNQLLRLKKVDTAALRT HLAQLETQWAELLTRIPVVQEKLHQLQMEKLPSRHAITELMSWISLMENIIQEDQNKILE AVGSEVVQTYIQKYKGFEIDLSCKQLTVDFVNQSVLQISSQDVEGKRSDKTDFAERLGAM NRRWQILQGLISEKITLLESLLESWLEYESGVQSLKTWISIQEEKLKKKPRIEDVASVQN LLKDCQELEELVKEKEKDLEKVEEKGCSLIQGKKGDASAIVMETLKRLNQAWTNLDQLVG QVKISLRAMLEQWSLYKRASEEIHGYLMEGQYSISRLRFLTGSPEAVLVQVENLEGLQEE LEKQESSVKKFGCLTEQLLKDCHCTVADSLTTTLTDINHRWNLLLEQISEQLRSSKNLLQ QWQCYKELHDSNSKDVQRLEERAECLLNSSTHSVTTEQEVKNWIHDCNDLLKAHSSVQAK LQQLTDAEEQLRLQVEPSSMATIHTDYLSLSRRLATVGHALYRQQELMKAGLKDYESFRE ELRCLSRWPEEAQEVLKESDPTASADLSAVQELMDKLKIQMLNLSRLSPDLERLNRLGYR LPLNDQEIKTLQNLNRNWTSTSAHSTERFSKLQALVLQRQSFLEKCETWLSFLNQTEEKL GTEISGNYQSLLKQQREHELFHAEMFSRQQILYSIISDGHQLMNQERVEDRDDFGLKLAL LSNQWQGVVRRAQQRRGIIDALVCQWQRYTELSDKLRHWLQEEALDREEETQQQGRVMAL QQARGVLDRIQLKERVLQRQQGSYILLVEAGRQLLLSADTQAEALLQEELTELQERWRSA SIRLDQKKKELLSLLKDWEQCEKGIAASHEKLRAFKRKLSLPLPDHHEELHNEQIRCKEL EGSTDGWADDVAALCVLRDSLLCSLSSDDLTVLQERLELLQRQWEETCHQLTLRRQQVSE KLNEWAVFNEKNKELCEWLTQMESKVSQNGDITIEEMIEKLRKDYQEEISVAQENKQQLE LMGERLAHSSHESKAAEIQYKLSKVNERWQHLLDLIAARVKKLRETLVAVQQLDKNMSSL RSWLTNVETQLSRPIVYETCDTNEIQKKLSQQQDLQRDIEKHSTGVASVLNLCEVLLHDC DACATESECDSIQQATRSLDRRWRNICAVAMERRLKIEETWRLWQKFLDDYSHFEDWLKA SERTAALPNSSGVLYTVAKEELKKFEAFQRQVQECLTQLELINKQYRRLARENRTDSSCS LRQMVHDGNQRWDTLQRRVASILRRLKHFIGQREEFETIRDGVLVWLTEMDLQLTNIEHF SECDVQVKIKQLRAFQQEIDLNSVKIGSVFSQGEALMEKSEPLDAAVIEEELDELQRYCR EVFGRVDRYYRKLTRLPLADDECDGSDREFDLDGSGELSDLQWEEGNSLPSTNSQTPSVS PAPLRANCSGRETPASVDSIPLEWDHDYDLEPMGSTMSSNKRGQDEEDEDVGSSSTAALK GDSARKVLDLDSHNASYSGYMRLMGDCRDSLSALKRAEGKLEEEESDLAGLNNPETAEPQ NTGVIKRWELIQAQSLNSSEDLLLRQQLTSDLENMEVWLSGIEEELAELKGRNLSTDIHT IDQRIKKLKDLQKEVDTHKPTVLSINLSSVRLVQSDGEENRKLRRRLKEMNSRWDRLCKA LQQWRAALQDALMQCQEFHELSHGLLLWLENIDRRRNEIVPIAAELDQHTLRARYKVLEQ IEQELRETEQSVSSLQELSVQLLVQAQGGESLEAQERVHVIGNRLRLLLNAVKSDLQLLQ RRLHASGDTHVPCVWPAVDDMDTSGSVSPVSVVSVPVQHHTLRSKCNVSGAGSSASLPRH RSLRGSACASSRCGSSAPHGGAAAARRQPFLLRVLRAALPLQLLLLLIVGLACLVPITED DYSCANHNNFARSFHPMLRYTNGPPPI NT seq 20424 nt NT seq  +upstreamnt  +downstreamnt atgtgtaaggattaccagactctgaagtacaaactcggctcagttgtcgagagtgctcat gctgttattgttgctcattctgtccagcacaaccccgaggacatgcggagagccctgacc aggctggaggcagtgaagttagagctgaccggtgctcagggcgacctcgatttgttcatc tgtaaaagcaaatccttcatcagcaagctaaggaaccttccagcagacctagcagatgca gtccgtgtggaattggacactgtcgtggaccagtggatggacacgtcagagaggatagaa accgaagcgaatcgtctcgcaaccgttcttgagttatggaatgaggttaactctgtggtt aatgacatcgagtgttggagcgccacctcagttagcgagctcaacgatggacctgttagt ctcttatccagtgccaacatggaggactgcctcagtcagtttaaggtggagattgagaat aaaaagctgctaatggagagccttcgtgtaaaagttaacgaactacaggaagtaacaaag aaccagcaagtggacaccgagctccaggtgatggcagctgatctgaggaagaagatcttc catgctgaggaggtttatgagcaggcctgttccatcctgagggacttcagctgtcagagc cggcaactccaggatgcgatttcccacatggctgaacaactggacactgtcgagaacacg ttgtcagagctatcacagtcatctgacccagaaaatgtggccaagataaaggagctccgg aagattctgaagcaggtggatggaggtttggacgtgacgggcgagtctctccgtgtgctc tgtagagtttatccagcacagcagctaacatctgtgggcgagagcatcacccagctggtg aagcggagcgaagcggccgctcatcgttccggacaaatcctccgaactctacagaaaaca cttctgcacagttttaacgaactcacacaggatttccatagctggctatcagagctgaaa tcaggaacagaagagacctctgaggaaacaggagaccttcctcgggttcctgctcagctg cagaggctcaaggtgtccctggagcgaatcagagagggtgaggaacatctgactagactt catgaagaagaagaaaagctcctcacacatctgtctgaatctgcagctggacgagttcag gagcatctggcctcgtgtcacctggcgctggataaatttattgcagcctgcagacagaga gtgcggtgtttagaggagagcgccgccctgcaggacaggttggaggtgtgtgttgacgag ttgagaaactggctgcggcagatggaggaaagcctaaagaaagaggcagttatttgtgga gcgagccagccaggagtccctgactgctccactcagctcaaaagagtggaagaaatacac aaagagctgctcgcaagaagaccatcactggagcgtctgtatcagtcctctctacccctg tccaaggagaacagcatcccagccgagcttctctcctcccatcaggctctgcttcaagag gcctggactcagctgctccacctgcaggaataccaggcgtttggggaggcgctcagggcg gtgggaaactggcttgaggaggtgaagggcaggctggagaaactggagagcactgagggg aataaagaggaggtggaggagagactggaaagagtgcaggatatccttttaatgaagggt gagggagaggtaaagctgaacatggctgccggtaaaggcgagcttgtcataaaaagcagt ggagacgctggacaggaagtgatccgttctaagctacaggaagtggaggatgcctgggca gcactacttttaagagctatgagctgccacagccgtctggagtggacggtgagtcaatgg ggactgtttgtggagtctcaagctcagctcaggacctggttagaggaggtggagtctgag gttaaaggtcctctggagcctcaacttggtctcagagaaaagaggcagcagctggacaga ctgtgtttgctcttggctgacgtcgaggaccaccagggggcactgtgttatttagaggag agcgctgctgagctgcacaagcgcaccagggacccggcctttaaggaggaggagactgct caacttagggctcagtttgatgatgtccgagctgctgcagaggagagagtccgtctttca gaaggtgtcgttttcgagcatgagaagtacatggcaactgtaagagagctcactgattgg ctaatgtccaaaggagaggagcttcagagatgttccgatccatctggagactctgcatcg gtcgagagaaagctgatggaagttcgggagctggtggcgcggggagcgcgcgaagggcgc gagcgtctgcggcgcgtgcggctgagcgcggagagcgcgtgcaggctgacggcggcgacg ggctgcgagctgatggacagcgaggtcctagcgctggcgcgagccctgcagcagtgggag ggacaggcgctgagggcgcgcgacactctggagaccgccgtcaccgtggcgaccggagct gagcgcgagcagcgtcgcctcgccgagcagctcgaggaagacaccgggcggctcgagcgg cagctaagagagtggagcgacgggctgaagcgctccgagaggcggaacagcggagctgac gcggtgcagggatggactgtggctcagggtgtactggaaggcctgcaagcagctgaagtc atggaggagaagctaaaagctcaacttaacgagctgtgtgggttttccagtgatctggga gctcagtcagagcgggtcagtgcgctcatcaaactgcacaacagtctgagtctgcgagca gctcgtgagtgtcagaataaggagaagctgctggagcagcgtttccgctcgtctctgcgt gatttccgtcagtggctggtcaacgccaacatctccacggctaaatgctttgactctcct cacagcattcaggaagcttccaccagcctccagaggattcaggagttcctgagtgacagc gagcaaggccaggacagattaaacgctgtgatctcccacggggaccgactcgccgccgtg gtgtctgctgacagggtggaggtggtcaggtccaaagccaacgctgccaaagatgactgg aacaacctgatggacaacctgaagcaaagagagactgtattacagggtctgcagtgtcag atgcaggagttcgaggtgagtgtggagcctcttcaggactggatcaacagaacagagatg agcgtacaggagagcagcgctcgtctacacgatctccctgctaagagactggagctgagc aaactgcagtcagtgttggaggagatgggctccatggaatcggagctaggaatgctgaga gagagagctcacagcctgtgggaaggtcagacggctgggaaaggttttgtgcacagggtt tgtcagcttgctgcacgctacctggccctgagcaaccgcactaaggagaaggtctccaga gtggagcgtgtggttggggagcatcagctcttctcccaaggcttacaggaacttcagagc tgggtttcagaagcccagcagatcctcgaaacctgccgaagtcccaacgctgacaaaagc gtgttgcttacccgaatgagccagcttgaggagctgttagcggcacgtcaggagcgggag atccaactgaagatgctcatcaccagaggagaagcggtgcagaggaacacctcagcggag ggtgtacctgtggttcgcaaacagatccaggaccttaaagactcctgggacttgcttctc tcagctgcgatacagtgcaaaagtcagctagaaggtgctttgtctcactggaccagctat caggaggacgtgagccagttcgagggctggctggaaagagtagacgagagtctggggaac tcggataaacactgtacggagatgagggagaagacagcgaatttacgccaagcgaagctg ctttatgaggaagtgttgagtcactcgagcttgttggagaccattgccacaaagggatcc aaccttcccgagcactcagccactcagcgggaggtagacgagctcagcacgcagtacaaa accattaaggataaagccaaggctgctgtcaagaaggcggaggcgctggtcctggtccat caggagtaccagcgaggtctgcacatgttcgaggactggctggaacaggagcagagcaac ctggctctcctttcacccctggatggagatgtgaatgcactggagaaaaccttgaaagag ctgcatatgctccagtcacgttgctctgagggccatgccttgctgaagtcggccctgtcc agtcgggagcaggtcatcccgtggggtgtccctcagattgaggacagggcgttggagacc gcacagagagagtggcaggcgtatcaggacaggctggagaacactcaagctagcctggag cagacgctcatcaggctgcagcagctggagggatgtttccagaacctggaccgctggctg gtagatattgagcttaaagtcagtctgaggagtgacagacgagccgagtgtgctgctaaa gagctccagctccagcagcttctgcagtgggaggtggaggctgtacagaagcagggtgag atggaggctctgagtgctttggctcagcaggttgtggaagactctcatgtcagcgctcgg gtcagcgctcgggtcactcagctcaccacccgctaccacgccctcctgctgcgcatacag gagaccatccgccagctgcaggaggaactgaggagcatcagtgaagctcaggtcgctctc agatccttctccgattggatgagtttgacgacgatgggtttaaaagtagccagcgaaagc aagcaagccccggatcgagcatctctggagaaaaagatgaaaaggctggaggctctacag cgtgatgtggacgaaggccatgccctgttcaagaccctccgtgagaaagccgagcaggcc gtctcctttctggatgaaagcggaacctgtcagctagagaaggaggtccaggagagccga tctcgactagaagagcttggcctggggatacgagccgagcatggagctactgagaagagc gcaatgctttataaagagtttcaggagcgttataagacccagctgcagtggatgagagat actcgagctctactcggctcttcggcagaaccaaaagctgagctctaccagagaaaagcc cagctggcaaagtataaggtgttggagcaaactctgctgtcccgggactctgccctcagt gccatgatggaaaaagggaaaacactgctgtctctcctccactctccctccatcacagaa aacatggaccggttacagagcgaatatcaggagctgtgtaacaccgtgaggagtcgggtg cagaagctggaggctcacgtaaagaaacaggaagagtatcacaccgaactccaggaagtg gaacgctggctgctgcagatgtccagccggatggtgacccctgaccccactccgggaggc gggctggaggcagccgcgcaacagctggccagacacaaggccatcatggaggagattgca ggctttgaggagcgtctggcgggtctgaaggagagaggagacgagctgatgtctggctgc accgaacgccttcaggctcgtgtacgccagcagatccagagccacctgcagggagcacga gacagttactcggccatctgcagcacggcacagcgcgtctatcagagtctggacagggag ctgcagaggcatgtcagcctgcgagacacactgcagcagtgtcagacctggctgttcaat atccaggaggaactgcagccgcctgcacaaacgccacgctacctggaggaggcactgatc cagctgaaacaggagcgagcacttcaggagcaggcaagtacgtatctgcagctgatctgc tccacatgtgacctgacggaggagaaggtgcaggagaccgccgctgatatccagcaagtc aaaatccaggttgaggaaagaatgctcgaatcccaagaactggcagacagctggagagaa atcgagagcctacgttccgatcttgagtctcatctccgagaagctgaaaagtttctgcag aacatgctgagaacaccagcagatcttgaaccaaaggtctctcagaatcagctggaccag gctcaggactttattcaggagatacaagccaggcaagctgatctggccagcctgagagag agcattggaaggcttgtgccatctcaggattcacctgtgctggtggaaataggtcgccta cgcagatcttggttagagcttgcaaagcaggctgcagagcttttggagcagagagaggag gatctccagaggagtggggattatcaagagtgcctgagcatggtagaagagctgtttgac caattgtccaaggaatgggattatctgtccaggggggatatggagagcaatgcagggtgt ttagatgccttgaagaagctctccatagatcttcaggaccagcggtgtgtattagaagat ttgagagataacaagaatgcaatcctgccacgccttacacttgaggacaaggaccttgtc aaggagcaggtaggttacctggagcaacgctggacccaaatggaagtgcaggttgaacag aagatacaggatacgattgaaaccctagaagacttaaatcatttagaggaccagttgcgg gaaacccaagagtgggctgaggtgcagcgaccatctctttctgatgtactgaaaaccagt ccccctcctgaccttgctcagagctttttatttgaccacttgagcttttgtgcagaacta gaggccaagcagcagcttattaatcaatctgtgtctgaggctgccatcctttatgctcat ctaggactaaatgagaaaaggagactgcagaccttggtgcaggatgttcaagaagcagta gaatctcttagctcgaaggcagctcaccaccgcaaaagccttaataaagtgttcacagag cggacacagttcctccaggccttggacagggctgctgcatggatcaagcagcaagagcag aggattctcgcagatgagcatgtggctctcgtgccagatgagctctccaagcaggtgtct atttgcaaaaacatatgtaacagcctaagggcatatcaagtggaactaacctcactttgg acacaaggaagggaacttgtaaaggatgcaacagaggatgagaagacagagaccattcaa agacttgaggagctccagggaacctttgaaacttccctccaaaggtgcacaaatcatttg cagcacctggagagagccttagttattcgaaagtacttcaaagatgatttggatagaatc tgtgagtggttgcgacatgcagaagcagccacattcccaataatagacctcaacaagaat gatgcggagctgcaaaaccagttagccaaataccagcagattttggatcaaacctcagca tatgagaacctgttgcttattgtccagcgggcaggacaggaagttctacccaccttaaat gaggtggatcactgctacctggatgagaaacttaacggccttccgcaacagtacaatggc attcttttgtcgaccaaagaaaagcgagacaggatccagcgagtgattctggagcgcagg gaattggagtccctcattgaagcgacacgtaaagctttggaggaacttcaggagcagtgc gatgccttagagaaacaatcaattagtggaagccttgaagatggggaaaggttgcacggt gactatgatgagatccagaccggtcttttaaaccttttccaagcgatgaatgagttgaag aataaaactcaggacttccattgcacaggacaaccatatacacgtgaggtcattgaccag cttgtcagtctttatggtagacttgatcaagagacaaaggaaaaggttaaacaactcaat ggaactttgaatgtattaaatgactacaggaccacaatggcaaaaatggatagtggcatt aatgcagtcagggagcatatggatgaacttaattctgagacgcagttagatgccatggag agattatcgaaactgcacaaaatggccaaagagctagatgagattactttttattctgaa ggattaactggaaagatagtagagtgcaaccagcactttgaccatgatacccttagaact caggtttccatgaaggagacacagcttcaagccttgaaagcaaacatttacaaaagcata gaagaatgtgaatgttgtgtggggagcaagcctagcttccagaccaagatcaaagaaagc ttgatttggctcaagagggttagagaggatctcagaggtttgtttacacttcaggaaatc aatgtgcatgttgtacaggatgagatcagatcaacagtcacacttcagagagaaattaaa tctaggcttcagttgctgaaaactttaagccaaaatgagaggacctccaaacagacattc cccagtgacatggagatctgtttgaaggatattgcagacttggagagtgaggttcaggaa tccctcacaaccaaacaggcggtcttgcagtcagcactatccttgctacaaatgtaccaa agtgccttgaggactattagccagtggtttgaagatgcagatgctgtcataaagcagaag aaccagaatctagaactggaagatctaacagagaggctcaaggaacttgaaaatgttttg acccaagaaccgaccataaagaaggcgattcaggatatcaagggcattctccctaaaatg gagagctttgtttattctggtgttgtaatgaaaaataaagaagccctcgagaccacttgt caaaggagtgctgatgtcatagaacagctgagaagtcaccaagaaaccttaaacagatgt tcttctcagtggacggcatttaaaaaagatagagaagtactcataactgaactgagtgaa gttgaaatgaaattagctgagtttagcacagctaaatcaagctctcttcaagaggctgag gacaagcttcgttttcaccaggattttgtgttccaacttgaggcttgtcaagataaactc tcaaacctgaaagaacattcagagcagtccgatctgaactgcatgtccggtgctgcggtt tgtcgttcagtttgtgcactagaccagcgatgcactcagttaaccagtgtagctaaagta caggagaaggcgctaaaggacacggtgcatgactggagaggcttcattgagaagctggag aagatgaggtctgtgtcagaggacctgcacagccgagttccagacagcgtggtggagaag gcagccagcactgtggccctacacaacctgttagagtatcacgactccttcagccgagag gtggagagagagaacagtgccctgactctcctcagacaccatgcccttcaccttctcctc cactctgatactgcattactaaagacctccaacaaccagaccagctgcatcagtaaccaa acaaccaggcttggcaagctgtcagccatgcccctcaagcctccttacatgaccatgaag caaaagatcacaccaaacaagacgccgatctcaaccagtaaccagtcagccacccctact acacagccagacacactcagctcacagcttaccatgcccatgacacaaccagccaggccc accacaaaatcaaccacgcccaatacacaattaaccacacccactacacattcaaccaca cccactacacattcatccacgcccactacacagcccgccatacccaacaaccacgtagac actccttgcaatcaaacagtcacacccagcaaccactttgaaatgtctagcacactaaca cccaaataccaaacaatcatacctgtcaatcatctggccacgcccatcaagcaggccatt aaaaccaacagtgaggatgctttctgtctgcgggagattcaggcaatgcaggagaaatat gagagcctgctgcagaaagtgtgtgtgagccggcagcaggttcaagtggaactgctggag cgagaggaggtggaaagggagctgggactcgttaaaggctggatccaggacacacagggc ctgttactcagccctacagctgacctggacaccctgctctctgacctggagaaggctcat ggcggtgttcagtctcagcgacaggctctggagcagattgcagatcgccagcagatgaaa tacaaagaccttcatgctgctgttccttctgagatcagcacccagctggcacaggtcaca ctggcactgggttcggcagaggaccaggtgcagagccgggagagagaagtgcagcacagc agagatgttaaagaagactttactgccagattgaaggacattgcggagaaagtcagcacc atctctgtgaaactgaagcagaagggtgtggatgtagaagaggccaaagaggagacggag actctgcgtgaggagctggaggactgctctcatgctctctctgagctggatgtggccatg caggagttcggagagcagaacccgctcctggcccggcagcttagcacgacactgaacaaa ctgaccgagctccactctcagaccagcagactcgcagagggaaggacctcaaggcttaag aaggctgagcagcactttgaggagtttaatgaaagactcaccctgatactgaactggact gaaaaagcagagactctggtttctaccagcatcgtctggagccccgcctctgtgatgcag gagcaaatccgtacacaccaggcgctgctgcgggagtggcggaggctgcagggtgagatg gaggcagtgattgagagagtggggtcgttgggagaagtggtgcacactgatgcacttcac cagcaggtggcagagctgagccgacacgccgaagagctgcagcaaagcaccaaaacacgc ctgctgaatctacaggatgctgcaaaggacctgagcaggctggagagtgaggtgaagagc ctccacaggtctattgagagagttcaggagacactggcctccccagagctggctcgtctc agcctcagagaacagctgctccagagacagcacctgctgacagaaatggagggatttaag gtgcaggttcaggctgtgcagaagtgtatgagcacgctgcagcttcctgaggatgccatg gtcacattacccctgtgtgtcactgcgcagagtctacagcaggacagcagccatctccaa cacaccaccatacagcagtgcaacatactgcaggaggccgtggtgcagtatgagcagtat gaacaggaagtgatgaaccttcagaagatgatcgaggaagcgcagcgtgttattcaggac cgacccgtcactacaggcaacatccatgagcttcagacgcagatacagcaccatgaggag ctgtcccagaagataaaaggctaccaggagcagatcgcagccctgaactccaagtgtaag atgctgacactgaaggccaaacacgccaccatgctgctaactgtcagcgaagtaggaggg ctctcagatggtctggaggagctggaggatgaagaagaggagatggtgaagcaccccaca acacacccctcggttgtcatgatgactgcaggtagatgtcacactctcctgtctcccgta acggaggagtcgggtgaggagggcaccaacagcgaggtctcctcccctccagcctgcaga tctccctcacccgggcctaacgccgacatctcccttaaccaggttccaggaaaggcccca ttaagtcgcgctcctctacaggaactgtatgaccagtccatggaatcggctgccacggct aatctggacgacttacagcgctcgtgggaaacgctgaagaacgtgatcagcgagaaacag aagagtctgtatgaggctctggagaggcagcagcattaccaggagtctttacagtccatc tccaccaagatggagtccattgaggcttcactcagtgaagggctagaacctggaaagagt cccgagagccagatggcagctcaccaggctttgatggatgaaatcctgatgctacaggat gagatcagcgctctgcaggcgtgtttctccgaggagctccagcgggatgaggagagcccc gagcaggacgcgggtgaccagctggcactgcactccaccctcactgtgctgggagaacgc atggccaccatccgcatgaaggcctcgggcaagcgccagctcctggaggaatgcttgaac gaacagctggaggaacagagacaggaacaagcccttcagcgttaccacagcgaagcagag gagctcgatcattggttgctcagcacacgagcgacgcttaactccgccctccagccgcat ccagaggacatggacatggaggagcagctgatcgactgtcagaacatgttgatggagatt gagcagaaggtgctgtgtctctccgagctttcggtacacagcgagagcctcctgctggag gggaaagccggcacgcgtggagacgccgagcagctcacgctcaagctgcacagccttaaa gccagtcttctggagctgcagcgcatcctacaggacaaacacacccacatccagggatct ttaatggagcaggaggagagtgagcctgactcagccttgactcagagtcccagcatactg gactggctcagtcaggcccggtccactcgcagccagcagcaccaggacacggtgcagaga caacgggaattagaggcacagctcgaggaacagaggaagctgatgcagtctgtggccagt cgaggggaggagcttctctcccactcccataccacacccactggagacagtgctgcaaat tgtcaggacatgtcggatccgggcgagagcacgagtctgagcacgagtgggaacgaacag ggcgatatgaggatgaagtgggagaatctgaataaagacctgaacaccaagctgcagttt ttgttcaacaccatgcaggatgaacagctcagctcggtctatcagagatctcgagtgtcc agcccaggaagtcttttcagaggagatcaactgacaccggacattttttcccccagtgct ttatttgagaattttaaccagaaactggaggaactagctgaggctgatgttaaacacgcg cacacccgggagaagtctctgtacgaagcagtgtgttcagcctccacctggctggacggt gcagagaacacactgctttccggccctgtgctcctgtctgacgactcggagatccagctg tttcatttagagggtttgaataaggaggtgaagaatgtcagcgaggaggtgagtaagtgt caggatgttctggagggacgtgatggaggaggtgatggcttgatcgaggaggtgctagat ggactggatgagagactgagattgatggattcactgctggagcagagatgcgacgggatt cgagacagacttcaggaacatacaacttttcaggtggaattgaggcagttgttcactgct atgagtgactccaagcatcagctgctgcagaagatgtgcggagctgcagatcgtccagcg tccagacagctagagactctgggtgaagcagagggcagtctaagggagtttgaacagagg ttgtgtgagatgaagactaaaggagaaactctgcagtcagacccagtcatcacacaggag ctgctcagactacaggacatgtatgaggagctggtggagatggtgggctcgaagcggagt gctctgaaccagatgttggtgttgaaggtacagtatgagaaagctttacaggacctgcag gagctcgtggacacggcacaggacaaaatggccgcggatcagaagatgactgcaggttcc gtgctcgaagttcagatccttctggacaagcacaaggagttttttcagggtctggaagcc catgtggtgctgacgcaggcgttctttaggcaggtcagtgtggtgatggtgcagagagag gttcaggttctggagcagactgtagctcaggctcacaccgtcctcaaacaggctcacaga aggggagtggaactggagggcatcctggaggagtggagcagttttgttggagattatcag gctctgtataagcagctggaggtggtggagagcagcattccagtcgtggggctggtggag gagacggacgagagactgagtgaaagaattgcactttatcagtgtctgaagagcaccctg gtggaacggcagcagcagctctatcaggttctagaggacggcaagagactgttactgcgt gtgtgctgttcagagctcgagactcagctcactcagctgggagaacactggctcagcagc accaccaaaatcagcaaagagctccagcgccttgactccacactcaaacactggaccagg tatcagagcgagtcagcagaactgggtcagtggttgtcctctgctctggatcggctcgag ttctggagcacgcagtctgttactgttcctcaggagctggagacggtccgagaccacctg tacgctttcctggagttctctaaagaagtggacgctaaatcgtccctgcgctcatctgtc ctgagccgcgggaaccagctactgaggctgaagaaggtggacacagcggcgcttcgcact cacctggcacagttagagacgcagtgggcagagcttctcacacgcatcccagtggtgcag gagaaactccaccagctccagatggagaaactgccgtctcgtcacgccatcactgagctg atgagctggatttctctcatggagaacatcatccaggaggaccagaacaagatccttgaa gcagtgggctcagaggtggtgcagacctacatccagaaatacaagggtttcgagatcgac ttgtcctgtaagcagctgacggtggactttgtgaatcagtcggtgctgcagatcagcagt caggacgtagaggggaagcgcagcgataagacagactttgcagagcgtctgggggccatg aaccggcgctggcagattcttcagggcctcatcagcgagaagatcacactgttggaaagt ttactcgagagctggttggagtatgagagcggagtccagagcctgaaaacctggatcagt atacaggaggagaagctgaagaagaaacccaggatcgaggacgtggcctcggttcagaac ctgctgaaagactgccaggagctggaggagttggtgaaagagaaagagaaggacttggag aaagtggaggaaaaaggatgctcgctcatccagggcaagaaaggagatgcctccgctatc gtcatggaaacgcttaaacggctcaaccaagcttggaccaacctggaccagttggttggc caggtaaagatcagtctgcgtgccatgctggagcagtggagtctgtacaagcgagcttct gaagagatccatggctacctgatggagggacagtactctatctcacgcctcaggttcctc accggttctccagaggctgtccttgtgcaagtggagaacctggagggtcttcaggaggag ctggagaagcaggagagcagtgtgaagaagttcggctgtctcaccgagcagctgctgaaa gactgtcactgcactgtggctgattccctcaccacaaccctcactgacatcaaccacagg tggaacttgctgctggagcagatttctgagcagttgaggagcagtaagaacctgctgcag cagtggcagtgctacaaagagctccatgacagcaacagcaaggatgtgcagagactggaa gagagggcggagtgtttactcaacagctccacccacagtgtgaccacagaacaggaagta aagaactggatccatgactgtaatgacttactgaaggctcatagctcggtccaggccaag ctgcagcagctgactgatgcagaggaacagttgaggctgcaggtggagccatcatccatg gcaaccatccacacagactacctgtcactcagccggcgcctagcaacagtgggacatgcc ctttacaggcagcaggaattgatgaaggcgggtttgaaagactacgagagcttcagggaa gagctgcgctgtctgagccggtggccagaagaggcacaggaggtgctgaaggagtcggat ccgaccgcgtctgcggatctgtctgctgtgcaggaactcatggacaagctcaagatccag atgctgaacctgagtcgtctgtctcctgatctggagcgtttaaaccgtctgggctacaga cttccactaaacgatcaggagatcaaaacccttcagaatctgaacaggaactggacgtcc acctcggcacacagcacagagagattcagtaagctccaagccctggtgctgcagagacag agtttcctggaaaagtgcgagacgtggctcagcttcctgaaccagacggaggagaagctc ggcactgagatctcaggaaattaccaaagtctgttaaagcagcaaagagagcacgagctg ttccatgctgagatgttcagtcgtcagcagatcctctactccattattagtgacggccat cagctcatgaatcaggaacgagtggaagacagagacgattttggcctgaagttggcgctg ttgagtaatcagtggcagggcgtggtgcggagagcgcagcagaggcggggcatcatcgat gcgctggtgtgtcagtggcagcgctacaccgagctctcggacaaactcagacactggttg caggaggaggctctggatcgtgaggaggaaacgcagcagcagggacgagtcatggcttta cagcaggctcgaggagttctcgaccgcattcagttgaaggaacgggtgcttcagaggcag cagggcagctacatcttgttggtggaggcaggaaggcagcttctcctgtcggctgatacc caggcggaggctctgctacaggaggagctgacggagctgcaggagcgatggaggagcgct agcatccgcctggaccagaagaagaaggagctgctctcgctactaaaggactgggagcag tgtgagaaaggaattgctgcgtcacacgagaagctgagagcattcaagaggaagctctct ctgcctttacctgatcaccatgaagagctgcacaacgagcaaatccgctgcaaggagtta gagggcagcacagacggttgggcggacgacgtggctgctttgtgtgtgctcagagactcg ttgttgtgcagcctgagctctgacgacctcacagtcctacaggagagactggagctgctg cagagacagtgggaggagacgtgtcaccagctaaccctgcgtaggcagcaggtgagtgag aagctgaacgagtgggccgtgttcaatgagaagaataaggagctgtgtgagtggctaact cagatggagagcaaggtgtctcagaatggtgacatcaccatcgaggagatgatcgagaag cttaggaaggactatcaggaggagatctctgtagctcaggagaataagcagcagttggag ctcatgggtgagagattggctcattctagtcacgagagcaaagcagctgagatccagtat aaactgagtaaagtgaacgagcgctggcagcacctgctcgacctcattgcagccagggtg aagaagctgagggagactctggtggcggtgcaacagttggataagaacatgagcagtttg cgttcgtggctcacaaacgtcgagactcaactgtcgcggccaatcgtctacgagacctgt gacacaaacgaaatacagaagaaactcagccagcagcaggatttgcagcgtgacattgag aagcacagcacgggcgtggcctcagtgttaaatctgtgtgaggttctgctgcacgactgc gacgcctgcgctacagagagcgagtgcgactccatccagcaggccacacgcagcctggac cgccgctggaggaacatctgtgccgtcgccatggagcgcaggctgaagatcgaggagacg tggaggttgtggcagaaatttttagatgattattctcactttgaggactggttgaaggct tcagaaagaactgcggctctgcccaactcatccggagtgctctacaccgtcgctaaagag gagctgaagaagtttgaggcatttcagaggcaagttcaggagtgtttaactcagctggag ctcatcaataagcagtaccggaggcttgctcgtgagaaccgcaccgactcgtcctgcagc cttcgccaaatggtgcatgatgggaaccagcgctgggacacgctgcagaggagagtggcg tccatcctgcgcaggctgaagcacttcatcggccagcgtgaggagtttgagacgatcaga gacggagttctggtgtggttgacagagatggacctgcagctcaccaacatcgagcacttc tcagagtgtgacgttcaggtcaaaatcaagcagctcagggcgttccagcaggagattgat ctgaactcggtgaagatcgggagcgtgttcagtcaaggtgaagctctgatggaaaagagc gagcctctggacgctgctgtaatagaggaggagctggacgagctgcagcgctactgcagg gaagtgttcggacgcgtcgatcgatactacaggaagctcacgcgtctgccgctggctgat gatgagtgtgatggttcagatcgtgagtttgacctcgatggctcaggtgagctctctgac ctccagtgggaggaggggaactctttacccagcactaacagccagaccccctctgtgagt ccggcgccgctgcgtgccaactgctcgggtcgggagactccggccagcgtggactccatc cccttagagtgggaccacgactacgaccttgagcccatgggtagtaccatgtcatcgaat aagagggggcaggatgaggaggatgaggatgttggtagcagctctacagcagctctcaaa ggtgactcggctcgtaaggtactggacctggacagccataacgcctcgtacagcggttat atgcgtctgatgggagactgccgagacagtttaagcgctctgaagagagccgagggaaag ctggaggaggaggagagcgacctggccggattaaacaatcccgagactgcagaaccacag aacacaggtgtgatcaagcgctgggagctcatacaggctcagtcccttaactccagtgaa gacttgctgctacggcaacagctgacctctgacctggaaaatatggaggtgtggcttagt ggtatagaggaggagctggctgagctgaaggggaggaacttgagcacagatatacacact attgaccaaaggatcaaaaaactcaaggatctacagaaagaggtagatacccataagccc acagtgctgtccatcaacctgagcagtgtcaggcttgtccaatcagacggtgaggagaac aggaagctgaggaggaggctgaaagagatgaactctcgctgggacagactgtgtaaagct ctgcagcagtggagagcagcgctacaggacgcgctaatgcagtgccaggagttccacgag ctgagtcatggcctcttgctctggttagagaacatcgaccgaaggaggaacgaaattgtt cccattgcagcggaactggaccagcacacgctccgagctcgatacaaagtgttagagcaa atcgaacaggagttgcgggagacggagcaaagtgtgagcagcctgcaggagctctcagtg cagctgctggtgcaggcgcagggcggcgagagtctggaggcgcaggagagagtgcatgtc atcgggaaccgtctacgcctgctgcttaacgccgtcaaatctgacctccagctgctgcag agacgactccacgcctcaggagacacacacgtgccgtgcgtttggcccgcggtcgacgac atggacacgtctggatcagtcagtccggtatcggtggtcagcgtgcctgttcaacatcac acgctacggagcaaatgtaatgtgtcaggagcaggatcctcagccagcctgccgcgccac aggtccctcaggggttctgcgtgcgcttcctctcgctgtggttcctccgcgccacacggt ggcgctgctgcggctcgccgccagcccttcctgctgcgggtcctgcgggcagctctgcct ctgcagctgctgctgctgctcatcgtgggtttggcgtgtctggtgcccatcactgaggac gattacagctgcgccaaccacaacaacttcgcccgctcctttcaccccatgctgcgctac accaacggccccccgcccatctga

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