Thalassomonas viridans: SG34_004685
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Entry
SG34_004685 CDS
T08831
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
tvd
Thalassomonas viridans
Pathway
tvd00260
Glycine, serine and threonine metabolism
tvd00261
Monobactam biosynthesis
tvd00270
Cysteine and methionine metabolism
tvd00300
Lysine biosynthesis
tvd01100
Metabolic pathways
tvd01110
Biosynthesis of secondary metabolites
tvd01120
Microbial metabolism in diverse environments
tvd01230
Biosynthesis of amino acids
Module
tvd_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
tvd_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
tvd_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
tvd00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SG34_004685 (thrA)
00270 Cysteine and methionine metabolism
SG34_004685 (thrA)
00300 Lysine biosynthesis
SG34_004685 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SG34_004685 (thrA)
Enzymes [BR:
tvd01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SG34_004685 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SG34_004685 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
WDE06228
UniProt:
A0AAE9Z439
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All DBs
Position
1091147..1093603
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AA seq
818 aa
AA seq
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MRVLKFGGSSLATAERFKQVAQIIKDKSQSSKVAVVVSAPQGVTNHLVAMAENISDEDKL
STDLQLFKTAIDTIIDDLSASLEGFNRQHAEQALANWEHQLSRYMQGVTMLSFCPEHIRA
RIISTGERLSVAILESVFAALDCEVSILEPEKFLFTSDESLNAVADLVLSKEKFAELYSQ
CKQIAVMPGFFGVNSRGEVTTLGRNGSDYSAAVLAVCAEAECCEIWTDVDGVFNADPRLI
KDAKLLDYLSYQEAMELSYFGASVLHPKTIGPIAQYHIPCLIKNTGNPQAPGTLIGNEND
QQKRVKAISNLNDLTMVNVSGPGMKGMVGMASRVFATMSRENISLVLISQSSSEYCISFC
IYSADALRAKQSLAEEFELELLNGLLEPISLTGDLSIVSLVGDGMHHQRGVAAKFFDSLA
QARVNVVAIAQDSSERSISVVIEQRKCTDALKVSHQNFFSFKPTIDVFMIGCGVVGSELI
AQIARQQPSLKAQNVDLKVYGLANSQGMVFNENGIDLDSWQQGMGENAVPATVENIKAFV
RGNHLINPVLVDCTSNEELAMGYVGFLEEGFHVVTPNKKSNTDSWQYYRELREAAQKTHR
RFLYETTVGAGLPVIDTLQGLIKAGDQLLKFEGILSGSLSYIFGKLEEGMPLSQATAIAK
ENGFTEPDPRDDLSGMDVARKLLIMARESGMQLELDDIEIESVLPESFDAGGDVSRFMAN
LEKLDDEFSLKVAAAKNEGKVLRYIGNINEGKCQVTIEAVDAAHPLYNIKDGENALAIHS
RYYQPLPFVLRGYGAGAAVTAAGVFGDLLRTLAWEQEH
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtactcaagtttggtggttcgtcgctcgccactgcagagcggtttaagcaagtg
gctcagatcatcaaggacaaaagccagtcatctaaggtggctgtggtggtttcggcgccg
cagggggtgaccaatcatttggtggccatggcggaaaatatcagcgatgaagacaaactc
agtaccgacttacaactttttaaaactgcaatcgacaccataatcgacgacttaagcgcc
agccttgaaggttttaaccgccagcatgcggagcaggcgctggcaaactgggagcaccag
ctgagccgttatatgcagggggtgactatgctgtcgttttgccccgagcatatccgggca
cgcatcatcagcacgggtgaaaggctcagcgttgccattctcgaatccgtttttgcggcg
ctggactgtgaagtgtctatcctggagccggaaaaattcctctttaccagcgacgaatcc
ctcaatgccgtggcggatctggtgctgagcaaggaaaagtttgccgagctctacagccag
tgcaagcagattgccgtgatgccgggctttttcggcgtcaacagccggggagaagtgacc
accctgggccgtaacggctcggattattcggcggccgtgctggcggtgtgcgccgaggcg
gaatgttgcgaaatctggaccgatgttgacggcgtctttaatgccgacccccggctgatc
aaggatgccaaactgctcgattatctttcctaccaggaggcgatggaattatcctatttc
ggcgccagcgtattacatccgaaaaccataggccccattgcccagtaccatattccctgc
ctgatcaaaaataccggcaacccgcaggcgccgggcactttgatcggcaacgaaaacgat
caacaaaaacgggtcaaggcaatctccaacctcaatgatctgaccatggtcaatgtttcc
ggcccgggcatgaaaggcatggtgggcatggccagccgggtatttgccactatgagccgg
gaaaatatttccctggtattgatcagccagtcttccagcgaatattgcatcagtttctgt
atttattctgccgacgccctgcgtgccaaacaaagcctggcggaagagtttgaacttgag
ctgcttaacggcctgctcgaacctatttcccttaccggcgacttgtctatcgtttccctg
gtgggggacggcatgcaccaccagcgcggcgtggcggccaagttcttcgattcgctggcg
caggccagggtcaacgtggtggccattgcccaggattcatccgagcgcagtatttccgtg
gtgatcgagcaaagaaaatgtaccgacgctctcaaggtcagccaccagaacttcttctcc
ttcaaacccaccatagacgtttttatgataggctgcggtgtggtgggcagtgagctgatt
gcccagatagcccgccagcagccgagcctgaaggcccagaatgtcgacctgaaagtgtat
ggcctggccaacagccagggcatggtgtttaacgaaaacggcatagatctcgacagctgg
cagcagggcatgggggaaaatgccgtgccggccacggtggagaatatcaaggcgtttgtg
cgcggcaaccatttgatcaacccggtgctggtggactgtacctccaacgaggaattggcc
atgggttatgtcggtttcctcgaagaaggtttccatgtggtcaccccgaataaaaaatcc
aataccgattcctggcaatattaccgcgagctcagggaagcggcgcaaaaaacccaccgg
cgtttcctttatgaaactacggtaggggcgggtttgcctgtgatcgataccctgcagggg
ctgattaaggccggcgaccagctgttgaaatttgaagggattttatccggctccctgtct
tatattttcggcaaacttgaagaaggcatgcctttatcccaggcgacggcgattgccaaa
gaaaacggctttaccgagccggatcccagggacgatctcagcggtatggatgttgcccga
aagctgctgatcatggcgcgcgagtccggtatgcagctggaactcgatgatattgaaatc
gagtcggtattacccgaaagttttgatgccggcggtgatgtcagccgctttatggccaac
ctggaaaaacttgatgacgagttcagccttaaggtggccgcggcgaaaaatgaaggcaag
gttttaaggtatatcggcaatattaatgaaggcaaatgtcaggtcaccatagaggcggtg
gacgctgcccatcctttatataacatcaaagatggtgaaaatgccctggctatccacagc
cgttattaccagccgctgccctttgtgctgcgcggttatggcgctggcgctgcggtaacg
gcagccggtgtattcggcgacttgctcaggaccctggcatgggagcaggaacactaa
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