Thermostichus vulcanus: NIES2134_114690
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Entry
NIES2134_114690 CDS
T05980
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tvn
Thermostichus vulcanus
Pathway
tvn00300
Lysine biosynthesis
tvn00550
Peptidoglycan biosynthesis
tvn01100
Metabolic pathways
tvn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tvn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NIES2134_114690 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NIES2134_114690 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NIES2134_114690 (murF)
Enzymes [BR:
tvn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NIES2134_114690 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
EutH
Motif
Other DBs
NCBI-ProteinID:
BAY50950
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Position
1497711..1499054
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AA seq
447 aa
AA seq
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MNTTLGAIAQALGLDTTHPNLPITGICTDSRQIAAGNLFVALRGETFDGHQFVDQAAAAG
AIALMVEAPLSSDLPQLQVANTLSAYQRLGQWWRQQCPAKVIAVTGSVGKTTTKEMIAAV
LSHYGAVLKTEANFNNEIGVPKTLLQLEPHHQFAVIEMGMRARGEIALLSQIAQPDVAVI
TNVGTAHIGRLGSREAIAQAKCELLAEMPAGGTAVLNADSPLLLPTAVQVWSGRTITYGL
EGGTLRGIYQPPQTLHVGGRTYTVPLAGAHHALNFLAALGVLQALDVESDRLPVQLTLEL
PSGRGGRYRLEPDILLLDETYNAGLESMVAALHLLRSLPGQRHLAVLGPMRELGAFSLSF
HEQVGATVAQLDLDGLFILDQGEEGAALAQGAGQIPTQQFGSHEELVEYLLRELQAGDRL
LFKASHAVALDRVVNQLRQRWPKLQSG
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
gtgaacaccaccctaggggcgatcgcccaagctttggggttagatacgacgcatccaaat
ctgcccatcacaggaatttgcaccgactcccgtcaaatcgccgccggcaacctgtttgtt
gccctgcggggggaaacctttgatggccatcaatttgtcgatcaggccgccgccgctgga
gcgatcgccctgatggtcgaagcaccgctgtcttctgatcttccccaactgcaggtcgcc
aataccctgagtgcctatcaacggttgggacagtggtggcggcagcaatgtccagccaaa
gtcattgccgtcactggctccgtgggcaaaaccaccaccaaggaaatgattgccgctgtc
ctcagtcactatggcgcggtcctcaaaaccgaagccaacttcaacaacgagattggcgtg
cccaaaacacttttacaactggaaccccaccaccaatttgcggtgattgaaatgggcatg
cgtgctcgcggtgaaattgccctgttgagtcagattgcccaaccggatgttgcggtgatt
accaatgttgggactgcccatattggccgccttggttcccgggaagccattgcccaagcc
aaatgcgaacttcttgctgaaatgcccgcagggggaacagcagtgctcaatgccgatagt
cccctacttttgccgacagcggtgcaggtctggtcagggcgcaccatcacctatggcctt
gaggggggcaccctacggggaatttaccaaccgccccaaaccctccatgtgggtggacgc
acctacaccgttccccttgcgggggcacaccatgccctgaactttctggctgcccttggc
gtgctgcaggccttggacgtcgagagcgatcgcctgcctgtacagttgaccctagaattg
cccagtggtcgcggtggtcgctatcgcctcgaaccagatattctcctcctagatgaaacc
tacaatgcgggcctggaatcgatggtggcggctttgcacctgttgcgatcgctccccggt
cagcgccatctggcggttcttggcccgatgcgggaattaggcgccttttctctctccttc
catgagcaggtgggggcaactgtggcccaactggacctcgatgggctcttcatcctcgat
caaggtgaggaaggggcagccctggcgcagggggcagggcagattcccactcaacaattt
ggttcccatgaagaattggtggagtacctattgcgggagttgcaagcgggcgatcgcctc
ctctttaaggcctcccatgccgttgcccttgatcgagtggtcaatcaactgcggcagcgc
tggccaaaactgcagtcgggttga
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