KEGG   Trichosurus vulpecula (common brushtail): 118828559
Entry
118828559         CDS       T10126                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial-like
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp00140  Steroid hormone biosynthesis
tvp01100  Metabolic pathways
tvp04913  Ovarian steroidogenesis
tvp04925  Aldosterone synthesis and secretion
tvp04927  Cortisol synthesis and secretion
tvp04934  Cushing syndrome
Module
tvp_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    118828559
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    118828559
   04925 Aldosterone synthesis and secretion
    118828559
   04927 Cortisol synthesis and secretion
    118828559
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118828559
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:tvp00199]
    118828559
Enzymes [BR:tvp01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     118828559
Cytochrome P450 [BR:tvp00199]
 Cytochrome P450, animal type
  CYP11 family
   118828559
SSDB
Motif
Pfam: p450 DUF761
Other DBs
NCBI-GeneID: 118828559
NCBI-ProteinID: XP_036591140
LinkDB
Position
8:complement(50412215..50433448)
AA seq 524 aa
MLARAILHRSALAKSRHYLLGSPREDVWTSSVRSMQLPARGGELSAFPLRLQGPRPFSEI
PSKGTNGWMNLFHFWMEDGMKNVHIRSLQGFQQLGPIYREKLGSSESVFIINPDDAACLF
KAEGPYPERHCFQPWLAYHTYRKKPIGILFKSSESWKKDRIFLNHFVFALDSVNNFEPLL
TPISEDFVKKIYKGIERSNQGKFTVDLSQNLFQFAFESICSILFGERLGLLEDFVDPNVQ
EFIDAVSTVFKTTIPMLSIPPELFRMVRAKIWRDHVASWDLIFERAEDYIQSFYQDQKMR
SGGTECYPGVVYCLLHKNTMNFEDIKANVAEMMAGAVDTTATTLQWCMYEMARNLKVQDM
LRAEVLAAQRDAQGDVKKMLKSVPLLKAAIKETLRLHPITDAITRYLPSDLVLRDYIIPA
KTLVQVAIFAMGRDPNIFSNPEKFDPSRWLQEDTYFRALGFGFGPRQCLGRRIAELEMTI
FLMHILENFKIEMHKLSDVGTIFNFILVPDKHIVFTFRPFKSQL
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgttagccagggcaatcttacatcggtcagctctggccaagagccgacattacctcctt
ggctcaccaagagaagatgtttggacatctagtgtcagaagcatgcagctgccagccaga
gggggtgagctgagtgccttccctctccggttgcaggggccccggcccttcagtgagatc
ccttcaaaggggaccaatggttggatgaatctgttccacttctggatggaggatgggatg
aagaacgtacatattcgatccttacaaggcttccaacagttaggcccaatttatcgggag
aaacttggcagttcagaatctgtttttatcatcaaccctgatgatgctgcctgcctcttt
aaggcagagggaccatacccagaaagacattgtttccaaccatggttggcttatcacacc
tacaggaaaaaacctattggaatcctgttcaagagctctgaaagctggaagaaagaccgg
attttcttgaaccactttgtgtttgctttggactcagtgaacaattttgagccccttctc
accccaatttcagaggactttgtgaagaagatttacaaggggattgagaggagcaaccaa
ggaaagttcacagtggacctcagtcagaacctgtttcaatttgcttttgagtctatctgt
agcattctgtttggggagcgtctgggactcttagaagattttgtggaccccaatgtccag
gagttcatcgatgctgtgtctacagtgtttaagactaccattccgatgctgagcatccct
ccagagctgttccgcatggtcagggccaagatctggagggaccacgtggcctcgtgggat
ctgatttttgagcgagctgaagattatatacagagcttctaccaggaccagaaaatgaga
tcaggaggcactgaatgttatccgggagttgtctactgtctcttacacaagaataccatg
aattttgaagatatcaaagccaatgttgcagaaatgatggcaggagcagtagacacgacg
gcaacgaccctgcagtggtgcatgtatgaaatggctcggaacctaaaggtacaagatatg
cttcgggctgaagtcctggctgcccagcgagatgcccagggagatgtgaagaagatgctc
aaatctgttccgcttctgaaagctgccatcaaagaaacgctgaggttacaccccattaca
gatgccataacaaggtaccttccatcggatttagttctccgggattacattattcctgcc
aaaacactggtccaagttgccatctttgccatgggaagggatcctaacatcttctccaac
ccagaaaagtttgaccccagcagatggctccaagaagacacctacttccgggctctgggc
tttggctttggtcctcgtcagtgccttgggaggaggattgcggagttggagatgactatc
tttctgatgcatattctggagaacttcaagatcgaaatgcacaaactttcagatgtgggg
accatctttaatttcatcctggtacctgacaagcacatagtgttcaccttccggcccttc
aagtcccagctgtaa

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