Trichosurus vulpecula (common brushtail): 118836003
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Entry
118836003 CDS
T10126
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00010
Glycolysis / Gluconeogenesis
tvp00020
Citrate cycle (TCA cycle)
tvp00620
Pyruvate metabolism
tvp00785
Lipoic acid metabolism
tvp01100
Metabolic pathways
tvp01200
Carbon metabolism
tvp01210
2-Oxocarboxylic acid metabolism
tvp04066
HIF-1 signaling pathway
tvp04922
Glucagon signaling pathway
tvp05230
Central carbon metabolism in cancer
tvp05415
Diabetic cardiomyopathy
Module
tvp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118836003 (PDHA1)
00020 Citrate cycle (TCA cycle)
118836003 (PDHA1)
00620 Pyruvate metabolism
118836003 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
118836003 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118836003 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
118836003 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118836003 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
118836003 (PDHA1)
Enzymes [BR:
tvp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
118836003 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
118836003
NCBI-ProteinID:
XP_036599231
LinkDB
All DBs
Position
2:443062337..443090136
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAIVSRVLTGASQKPAGRVLLAARNFANDASFDIKKCDVHRLEDEPPTTAVLTREE
GLKYYKTMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCVGLEAGINPTDHVITAYRA
HGFTYTRGLPVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNEKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGIRVDGMDVLCVREATKFAAAYCRSGKGPMLMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYCREPPFEVRGANQWIKYRSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgcggaaaatgctcgccatcgtttcccgcgtgctgacgggcgcctcccagaagccggct
ggaagagtgctattggcagcccgaaactttgcaaatgatgcttcatttgatattaagaaa
tgtgacgttcatcggcttgaggatgagcctcccaccacagcagtgctcaccagagaggaa
ggactcaagtactataagaccatgcagaccgtccgccggatggaattgaaggcagaccag
ctctataagcagaagatcatccgtggtttctgccacttgtatgatggccaggaagcctgt
tgtgtggggcttgaagctggtataaatcctacagaccatgtgattacagcctatcgagca
catggctttacctatactcgtggacttccggttcgagaaattctggcagagcttacggga
cgaagagggggatgtgccaaaggaaagggagggtccatgcacatgtacgccaagaacttc
tatggtggcaacggcattgttggagctcaggtacctttgggagctggcatcgccctagcc
tgtaagtacaatgaaaaagatgagatctgtttgactttgtacggagatggtgctgctaat
cagggtcagatatttgaagcttacaatatggcagctctgtggaagttgccttgtattttc
atttgtgagaataatcgatatggaatgggaacttctgtagagagagcagcggccagcact
gactattacaaaagaggagacttcattccaggaataagggtagatggtatggatgttctt
tgtgtccgtgaggcaacaaaatttgcagctgcctactgtagatcaggaaagggccccatg
ttgatggaactacagacatatcgttatcatggacacagcatgagcgaccctggtgtcagt
taccgtactcgggaagaaattcaggaagtaaggagtaagagtgaccctatcatgcttctc
aaggatagaatggtgaacaacaaccttgccagtgttgaagaattaaaggaaattgatgtt
gaagtaaggaaagagattgaggatgctgcccagtttgctacggctgatccagagccaccg
ttggaagaattaggctatcacatctactgcagagagccgccttttgaagttcgaggcgcc
aatcagtggatcaaatacagatctgtcagctaa
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