Trichosurus vulpecula (common brushtail): 118837732
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Entry
118837732 CDS
T10126
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00230
Purine metabolism
tvp01100
Metabolic pathways
tvp04022
cGMP-PKG signaling pathway
tvp04740
Olfactory transduction
tvp04925
Aldosterone synthesis and secretion
tvp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118837732 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
118837732 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
118837732 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
118837732 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
118837732 (PDE2A)
Enzymes [BR:
tvp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
118837732 (PDE2A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
118837732
NCBI-ProteinID:
XP_036600686
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Position
2:125638808..125805753
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AA seq
953 aa
AA seq
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MGQACGHSILCRSQQCPARPGEPEPRGQQVFLKPDEEPPPPPPQQQPCADTLQEALLSLG
SVIDVSSLHDVIKEAISAVLPKVETVYTYLLDGESRLVCADPPHDLPQEGKVRDAVQAWE
RLSCSGLGPSDLPEKALTGLTAPLAADRQVLVVPLVDKEAGGVVATILVHCAQLSEGDEQ
SLQAIEKHTLVALKRLRTLQQRQPRPLPVPEPSSLPTLLARPNGAVSIGTGGYSDLDSRI
LQLCGELYDLDASSLQLKVLHYLQQETESSTCCLLLVSEDNLQLSCQVIGDKVLGEEVSF
PMTVGCLGQVVKNKESITLKDLTSEEVTQLQSLVGCELQSMLCVPVISRATNQVVALACT
FNKQGGETYTDWDEHKILHCFCYTATVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDD
VSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDETYEIRIPADQGIAGHV
ATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWF
SKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYDKLLGDG
IQPVSAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDRQTLVRFCLMVKKG
YRDPPYHNWMHAFSVSHFCYLLYKNLELSKYLDDIEIFALFVSCMCHDLDHRGTNNSFQV
ASKSVLAALYSSEGSVMERHHFAQAIAILNTQGCNIFDHFSRKDYQRMLDLMRDIILATD
LAHHLRIFKDLQKMAEVGYDPKNKHHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKE
FFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQELFPRAAELYERVA
TNREQWTKVSHKFTIRGLPSNNSLDFLDEEYDIQDPGDDGDKVNGCCKLDEEE
NT seq
2862 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcgtgcggccactccatcctgtgccggagccagcagtgcccggcgcggccc
ggggagcccgagccgcggggccagcaggtcttcctgaagccggacgaggagccgccaccg
ccaccgccgcagcagcagccttgcgccgacaccctgcaggaagccctgctgagtttgggc
tctgtcattgatgtctccagtcttcatgatgtcatcaaagaagccatctctgctgtgctc
cccaaagtggaaaccgtctacacttacctgcttgatggagaatcccggctagtgtgtgca
gaccccccacatgatctaccccaggaggggaaagtccgagacgccgtccaggcctgggag
cggctgagctgcagcgggctgggcccctcagacttgccagagaaagcattgacggggctg
actgccccactggctgctgacagacaagtgctggtagtcccactggtggacaaggaagct
ggaggtgttgtggccaccatcctggtacactgtgcccaactcagcgagggggatgagcag
agcctgcaggccatagagaagcacacgctagtggccctgaagaggctgaggacactgcag
cagcgtcagccccgccccctgccagtgccagagccctcttccctgcccaccttgctggcc
cggccaaatggggccgtgtctattgggacaggtggctacagtgacctggacagccggatt
ctgcagctttgtggggaactctatgacctggatgcctcttcccttcagctcaaagtactc
cattatttgcagcaggagactgaatcctcaacctgctgcctcctccttgtttcagaggat
aaccttcagctctcctgtcaggtcatcggagacaaagtacttggagaagaagtcagtttt
ccaatgacagtggggtgcctgggccaggtggtgaagaacaaggaatccatcacactgaag
gacctcacttcagaagaggtgacgcagcttcagagcctcgtgggatgtgagctgcagtcc
atgctctgtgtccctgtcatcagccgggctaccaatcaggtggtagccttagcctgcact
ttcaacaagcagggaggagagacgtacacggactgggatgagcacaagatactccactgt
ttctgctacacagctactgtccttaccagcaccctggccttccagaaagaacagaagctc
aagtgtgagtgccaggctcttctccaagtggcaaagaacctcttcacacacttggatgat
gtctctgtcctgctccaagaaatcatcacagaagcccggaacctcagcaatgcagagata
tgctccgtgttcctgttggatcagaatgagctggtggccaaggtgtttgatggtggtgtt
gtggatgatgagacctatgagatccgcatccctgcagaccaagggatcgcgggtcacgtg
gctaccacaggccagatcctgaatatcccggatgcctatgcacatcccctgttctaccga
ggtgtggatgacagcacaggcttccgcacccgcaacatactctgcttccctatcaagaat
gaaaaccaagaggtaattggtgtggccgagctggtgaacaagatcaatggcccctggttc
agcaagtttgatgaggacctggccacagccttttccatctactgtggcatcagcatcgct
cattctctcctatacaagaaagtgaatgaagcccagtatcggagccacttggccaacgag
atgatgatgtatcacatgaaggtctctgatgacgagtacgacaaactcctcggagatggg
attcagccagtctcagctattgactccaactttgccagtttcacctacacccctcgctct
ctccctgaggatgacacctccatggccatcctgagtatgctgcaggacatgaactttatc
aacaactacaagattgaccgacagacattggtccggttctgcctgatggtgaagaagggc
taccgagaccctccctatcataactggatgcacgccttctctgtctcccacttttgctac
ctgctctataagaacctggagctgtccaaatatctggatgacatcgagatctttgccttg
tttgtctcctgcatgtgccatgacctggaccacagaggcaccaacaactccttccaggtg
gcttcgaaatccgtgctggctgcattgtacagctctgaaggctctgtcatggagagacac
cactttgctcaggcgattgccatcctcaacacccagggttgcaacatctttgatcacttc
tcccggaaggactaccagcggatgctggatctgatgagagacattatcttggctactgac
ctagcccaccacctgcgcatcttcaaagaccttcagaagatggctgaagtgggttatgac
ccaaagaataaacaccaccacagcctcctgctctgcctgctcatgacctcctgtgacctc
tcagaccagaccaagggctggaagaccactcggaagattgcggagctgatctacaaagag
ttcttctcacagggagacctggagaaggccatgggtaaccggcccatggagatgatggac
cgagagaaggcttacatccctgagctccagatcagcttcatggaacacatcgccatgcca
atctacaagctgctgcaggagttgtttcccagagctgcagaactgtatgagcgtgtcgcc
accaaccgggagcagtggaccaaggtgtcccataagtttaccattcgaggcctgcccagc
aacaactctctggacttcctggatgaggaatatgacattcaggatccgggtgatgatggc
gacaaggtcaatgggtgctgcaagctggatgaggaagagtga
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