Trichosurus vulpecula (common brushtail): 118837733
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Entry
118837733 CDS
T10126
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00230
Purine metabolism
tvp00670
One carbon pool by folate
tvp01100
Metabolic pathways
tvp01523
Antifolate resistance
Module
tvp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118837733 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118837733 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118837733 (GART)
Enzymes [BR:
tvp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
118837733 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
118837733 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
118837733 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_5
Sacchrp_dh_NADP
RimK
Motif
Other DBs
NCBI-GeneID:
118837733
NCBI-ProteinID:
XP_036600687
LinkDB
All DBs
Position
2:complement(367766226..367806858)
Genome browser
AA seq
1011 aa
AA seq
DB search
MAVPVLIIGNGGREHTLAWKLAQSPHVSQVIVAPGNAGTANNGKISNSAVSVNDHTALSQ
FCKEQKIELVVVGPEAPLAAGIVGNLTSAGVRCFGPTAKAAQLESSKKFAKEFMDRHGIP
TAKWKAFTDPEEACNFVMSADFPALVIKASGLAAGKGVIVASSKEEACKAIQDIMQDKAF
GAAGDTVVIEEVLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDHGPNTGGMGAYCPAP
QVPKDLLLKIKNTILQRTVDGMQQEGVPYVGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDFYEVIQSVLDGQLSNSLPVWLEDSAAVTVVMASKGYPADYTKGMEITGIPEA
RALGLEVFQAGTSLKENKVVTNGGRVLTVTAIQKDLMSALQEANKGITVIKFEGAVYRKD
IGYQAISFLKQSRGLTYKESGVDIAAGNELVKKIKPLAKATSRPGCNVDLGGFAGLFDLK
AAGYKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDVSTAETVIAGIAKACEKAGCALLGGETAEMPGVYPPGEYDLAGFAVGAMERDQKLP
QLDRITEGDVIIGIASSGVHSNGFSLVRKIVENSSFQFSSLAPDGCGNQTLGELLLNPTK
IYSRTLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKFGVDLDARCWKIPRIFSWLQHEG
RLSEEEMARTFNCGIGAVMVVQKDLAKQVLKNVHQQEEEAWIIGNVVTCPTGSSRVKVNH
LIPTMQINGSVSLVNESLKTCLGVQPKRVQVAVLISGTGTNLQALIDSTQESTSYAQIVV
VISNKAGVAGLEKAENAGIPTKVIDHKLYKSRSEFDSEVDNVLEEFSVDLVCLAGFMRIL
SGPFVQKWNGKILNIHPSLLPSFKGSNAHEQVLEAGVRITGCTVHFVAEQVDSGQIIIQE
AVPVMRGDTVATLSERVKIAEHKAFPAALQMVASGAVKLGENGKICWSKEE
NT seq
3036 nt
NT seq
+upstream
nt +downstream
nt
atggcagtccctgtgcttataattggcaatgggggaagggaacacacactggcttggaaa
cttgctcagtctcctcatgtcagccaggtgatagttgccccaggaaatgcaggaacagcc
aacaatgggaagatttcgaattcagctgtgtcagtcaatgatcatactgccctctctcag
ttctgcaaagaacagaaaattgaacttgtagttgttggaccagaggctcctcttgctgct
ggaattgttgggaatctaacgtctgctggagtgaggtgttttggtcccacagcaaaggca
gctcagttagagtccagcaaaaaatttgccaaggagtttatggaccgacatggaatccca
actgcaaagtggaaagctttcaccgaccctgaagaagcctgcaactttgttatgagtgca
gattttcctgctttggttataaaagccagtggtctggctgctggtaaaggagtaattgtg
gctagtagcaaagaagaggcttgcaaagcaattcaagacataatgcaggataaagctttt
ggagcagctggtgatactgttgtaattgaagaagttcttgaaggagaagaggtgtcttgt
ttatgttttactgacggtaagactgtggccccaatgccaccagcacaggaccataagcga
ttgctggatggagaccatggccccaatacaggaggaatgggagcttattgtccagcacct
caggttcctaaagatctgttattaaaaattaaaaataccattcttcagagaacagtagat
ggcatgcagcaagaaggtgttccatatgtaggaatattgtatgctggtataatgcttacc
aaggatggcccaaaagttcttgagtttaattgcagatttggggatccagaatgtcaggtg
attcttccacttcttaaaagtgatttttatgaagtaattcaatcagttttagatggtcag
ctttctaattctctgccagtttggcttgaagatagtgctgctgtaactgttgtcatggca
agtaaaggttatcctgcagattacaccaaaggcatggagataacaggaattcctgaggct
agagctttaggcctggaggtgttccaagcaggcacatccctgaaagagaataaagtagta
actaatggtggtagagttcttacagtaacagccatccagaaagatctgatgtcagctctt
caagaagccaataaaggaataactgttataaaatttgaaggagctgtttatagaaaagac
attggctatcaagctatctctttcctaaaacagtccagaggcttgacttataaggaaagt
ggggtggatattgcagctggcaatgaactggttaagaaaattaagcctttagctaaagcc
acctccagacctggatgtaatgtagaccttggaggatttgctggtctctttgacttaaaa
gcagccggttataaagatccccttctggcatctgggacagatggagttggaaccaagtta
aagattgcccaacaatgcaataaacatgataccattggtcaagatttggttgcaatgtgt
gtcaatgatattttggctcaaggagcagagcctctgtttttccttgattatttttcctgt
ggaaaacttgatgtcagcacagctgaaactgtcattgctggtatagcaaaagcatgtgaa
aaagcaggatgtgctcttttgggtggtgagacagctgaaatgcctggtgtgtatccccct
ggagaatatgaccttgcaggttttgctgttggtgccatggaacgagatcaaaagctccct
caactggacagaatcactgagggggatgttatcattggaatagcctcttctggagtccat
agtaatggattcagccttgtaaggaagattgtagaaaattcttccttccagttctcctct
ttagcacctgatggatgtggtaatcaaactctaggggaattgttgttaaatccaaccaaa
atctatagccgaacattgttacctgttcttcgttcagggcatgttaaggcctttgcccat
attactggaggtggactacttgaaaacatccctagagttcttcctgagaaattcggggtg
gatttggatgctcgatgctggaagatccctaggatattctcatggcttcagcatgaggga
cgcctctcagaagaggaaatggctaggacatttaattgtggaattggggctgtcatggtg
gtacaaaaagatctggctaagcaagttctgaagaatgtacaccagcaagaagaggaagcc
tggataatcgggaatgtagttacttgtcctacaggttcttcccgtgtgaaagtcaatcat
ctgattccaacaatgcagataaatggatctgtttcattagtgaatgaatctttaaagact
tgcctcggcgtacaaccaaagagggtacaagtggctgttctaatatctgggaccggcaca
aatctccaggccttaatagatagcactcaggaatcaacaagctatgcacaaattgttgtt
gttatctctaacaaagctggagtggcagggctagagaaagcagaaaatgctggtattcct
actaaggtaatcgatcataaattatataaaagtcgttcagaatttgacagtgaagttgac
aatgtccttgaagagttctccgttgacttagtctgtcttgcaggattcatgagaatttta
tctggtccttttgtccaaaagtggaatggtaaaatactcaacatccacccatcattgctc
ccttcttttaagggttcaaatgcccatgagcaggttcttgaagctggagtgagaatcact
ggctgcacagtacattttgtggctgaacaagtggattctggacaaattattattcaagag
gctgtcccagtaatgagaggtgacactgttgcaactttatcagaaagagtgaaaatagca
gagcataaagcatttcccgccgctttacagatggtggccagtggtgcagtaaaacttgga
gaaaatggaaagatttgttggagtaaagaggaatga
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