KEGG   Trichosurus vulpecula (common brushtail): 118840956
Entry
118840956         CDS       T10126                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp01522  Endocrine resistance
tvp04015  Rap1 signaling pathway
tvp04020  Calcium signaling pathway
tvp04024  cAMP signaling pathway
tvp04072  Phospholipase D signaling pathway
tvp04081  Hormone signaling
tvp04082  Neuroactive ligand signaling
tvp04261  Adrenergic signaling in cardiomyocytes
tvp04270  Vascular smooth muscle contraction
tvp04540  Gap junction
tvp04611  Platelet activation
tvp04713  Circadian entrainment
tvp04714  Thermogenesis
tvp04724  Glutamatergic synapse
tvp04726  Serotonergic synapse
tvp04728  Dopaminergic synapse
tvp04730  Long-term depression
tvp04750  Inflammatory mediator regulation of TRP channels
tvp04911  Insulin secretion
tvp04912  GnRH signaling pathway
tvp04913  Ovarian steroidogenesis
tvp04915  Estrogen signaling pathway
tvp04916  Melanogenesis
tvp04918  Thyroid hormone synthesis
tvp04921  Oxytocin signaling pathway
tvp04922  Glucagon signaling pathway
tvp04923  Regulation of lipolysis in adipocytes
tvp04924  Renin secretion
tvp04925  Aldosterone synthesis and secretion
tvp04926  Relaxin signaling pathway
tvp04927  Cortisol synthesis and secretion
tvp04928  Parathyroid hormone synthesis, secretion and action
tvp04934  Cushing syndrome
tvp04935  Growth hormone synthesis, secretion and action
tvp04961  Endocrine and other factor-regulated calcium reabsorption
tvp04962  Vasopressin-regulated water reabsorption
tvp04970  Salivary secretion
tvp04971  Gastric acid secretion
tvp04972  Pancreatic secretion
tvp04976  Bile secretion
tvp05012  Parkinson disease
tvp05030  Cocaine addiction
tvp05031  Amphetamine addiction
tvp05032  Morphine addiction
tvp05034  Alcoholism
tvp05142  Chagas disease
tvp05146  Amoebiasis
tvp05163  Human cytomegalovirus infection
tvp05165  Human papillomavirus infection
tvp05200  Pathways in cancer
tvp05207  Chemical carcinogenesis - receptor activation
tvp05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    118840956 (GNAS)
   04020 Calcium signaling pathway
    118840956 (GNAS)
   04072 Phospholipase D signaling pathway
    118840956 (GNAS)
   04024 cAMP signaling pathway
    118840956 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    118840956 (GNAS)
   04081 Hormone signaling
    118840956 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    118840956 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118840956 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    118840956 (GNAS)
   04922 Glucagon signaling pathway
    118840956 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    118840956 (GNAS)
   04912 GnRH signaling pathway
    118840956 (GNAS)
   04913 Ovarian steroidogenesis
    118840956 (GNAS)
   04915 Estrogen signaling pathway
    118840956 (GNAS)
   04921 Oxytocin signaling pathway
    118840956 (GNAS)
   04926 Relaxin signaling pathway
    118840956 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    118840956 (GNAS)
   04918 Thyroid hormone synthesis
    118840956 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    118840956 (GNAS)
   04916 Melanogenesis
    118840956 (GNAS)
   04924 Renin secretion
    118840956 (GNAS)
   04925 Aldosterone synthesis and secretion
    118840956 (GNAS)
   04927 Cortisol synthesis and secretion
    118840956 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118840956 (GNAS)
   04270 Vascular smooth muscle contraction
    118840956 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    118840956 (GNAS)
   04971 Gastric acid secretion
    118840956 (GNAS)
   04972 Pancreatic secretion
    118840956 (GNAS)
   04976 Bile secretion
    118840956 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    118840956 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    118840956 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    118840956 (GNAS)
   04728 Dopaminergic synapse
    118840956 (GNAS)
   04726 Serotonergic synapse
    118840956 (GNAS)
   04730 Long-term depression
    118840956 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118840956 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118840956 (GNAS)
   04714 Thermogenesis
    118840956 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118840956 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    118840956 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    118840956 (GNAS)
   05165 Human papillomavirus infection
    118840956 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118840956 (GNAS)
   05142 Chagas disease
    118840956 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    118840956 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    118840956 (GNAS)
   05031 Amphetamine addiction
    118840956 (GNAS)
   05032 Morphine addiction
    118840956 (GNAS)
   05034 Alcoholism
    118840956 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    118840956 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118840956 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118840956 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tvp04147]
    118840956 (GNAS)
   04031 GTP-binding proteins [BR:tvp04031]
    118840956 (GNAS)
Exosome [BR:tvp04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   118840956 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   118840956 (GNAS)
  Exosomal proteins of colorectal cancer cells
   118840956 (GNAS)
  Exosomal proteins of bladder cancer cells
   118840956 (GNAS)
GTP-binding proteins [BR:tvp04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    118840956 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc GTP_EFTU TniB Rad17 AAA_29 FtsK_SpoIIIE
Other DBs
NCBI-GeneID: 118840956
NCBI-ProteinID: XP_036604239
LinkDB
Position
3:complement(188337446..188630073)
AA seq 423 aa
MGMCYSLRARILGAHHPSISYSGRGPAVALETGDLPGGQQPDSGDPQSRSRLRELELARL
KAERKRSKGIDKSLKAEKREYRQTHRLLLLGAGESGKSTIVKQMRILHVNGFNAEEKKMK
IQDIKNNIKEAIETIVTAMGNLAPPVELANPENQFRIDYILNLANQIDFDFPPEFYEHTK
TLWQDEGVKACYERSNEYQLIDCAQYFLDKIDVVKQNEYTPSDQDLLRCRVLTSGIFETK
FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALN
LFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPDDATPEPGED
PRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQY
ELL
NT seq 1272 nt   +upstreamnt  +downstreamnt
atggggatgtgctacagcctccgagcccggatcctgggcgcccatcacccctccatctcc
tacagcggccggggccccgcagtcgcgctggaaactggcgacctccccgggggacagcag
ccggactcgggcgaccctcagtcgcggagccggctgcgggagctggagctggcccggctg
aaggcagagagaaagcgaagcaaaggcatcgacaagagcctgaaggcggagaagcgcgaa
tacaggcagacccaccggctgctgctgctgggtgctggtgaatctggtaaaagcacaatt
gtaaaacagatgaggatcttgcacgtcaatggatttaatgctgaggagaaaaaaatgaaa
attcaagatattaaaaataatattaaagaagctatagagacaatagtgacagcaatggga
aatttggcacctccagttgagctagccaatccagagaatcagtttcgaattgactacatt
ttaaacttagctaaccagatagactttgacttcccaccagaattttatgaacatactaaa
acactttggcaagatgaaggtgtgaaagcctgctacgagagatctaatgaatatcagttg
attgattgtgctcagtactttctagacaagattgatgtagtcaaacagaatgaatataca
ccatctgaccaagatctcctcagatgcagagtattgacatcaggaattttcgaaaccaaa
tttcaagtggataaagtaaattttcacatgtttgatgtcggaggacagcgagatgaacgt
agaaaatggatccagtgttttaatgatgtgactgctataatatttgtggtggccagcagt
agctacaacatggttatacgagaggacaatcagaccaatcggcttcaagaagcactaaac
ctcttcaagagtatctggaacaacaggtggctacggaccatttcagtaattctattcctg
aataaacaggatttattagcagagaaagttttggcagggaaatctaaaattgaggactac
tttccagaatttgctcgctacactacaccagatgatgcaacacctgagcctggtgaggat
cccagagttacaagggccaagtattttattagggatgaatttcttagaatcagcacagca
agtggagatggaaggcactactgctacccccacttcacatgtgcagtggatacagaaaac
atcagaagggttttcaatgactgtcgggacattattcaacggatgcaccttcgtcaatat
gagttattgtga

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