Trichosurus vulpecula (common brushtail): 118844759
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Entry
118844759 CDS
T10126
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00790
Folate biosynthesis
tvp01100
Metabolic pathways
tvp01240
Biosynthesis of cofactors
tvp01523
Antifolate resistance
tvp04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118844759 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
118844759 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118844759 (FPGS)
Enzymes [BR:
tvp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
118844759 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
118844759
NCBI-ProteinID:
XP_036608629
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Position
3:161135608..161167559
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AA seq
589 aa
AA seq
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MMREFWSLWPISSLCLKGLKLWFKVSMIFRRVSTYLSWDENASFEDAVRTLNTLQTNAGF
LEQIKRERGDPQVQLEAMKHYLVRSGLQIEDLDQLKIIHVTGTKGKGSTCAFTERILRGY
GLKTGFYSSPHLVQVRERIRINGEPISPELFTKYFWRLYNRLEETKDGSCVSMPPYFRFL
TIMAFHVFLQEKVDLAVVEVGIGGAYDCTNIVRKPVVCGISSLGIDHVNILGDTIEKIAW
QKGGIFKPGVPAFTVSQPDSPLEVLKDQARKLMCPLYLCPPLEAFEEEAQPLHLGLAGDH
QRGNAALALQLARCWLQQQGHKGIGELKATRLTSQRALPLAPVFYPTLSMKQGLQDTEWL
GRTQMLRRGALTWYLDGAHTTSSIQASVRWFRRAVLDQEKLNNGPEVRVLLFNVTGERDT
GALLKLLQPCQFDYAVFCPNLTEMSSVGNADQQNFTVTLDHMLTRCLENQKQWNQLAEQK
AGVDPWLAQAPEPGSGPLHGPLLLVPPAPRPLNTNSLVFSCISHALQWISQGRDPHFQPS
SPPRGLHSHPVASSGAVLLKEASSIQVLVTGSLHLVGGVLKLLDPTLSQ
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgatgagggagttctggagtctttggccaatatctagcctgtgccttaaaggactcaag
ttatggtttaaagtttctatgatttttcggagagtatctacctaccttagttgggatgaa
aatgcttcctttgaggatgctgtgcggaccctcaacacccttcagaccaatgctggcttc
ctagagcagatcaagcgagaacggggagacccacaggtgcagctagaagccatgaagcat
tatttagtccgaagcgggctgcagatagaggatttagaccagctgaagatcatccatgtg
actgggaccaaagggaagggctccacttgtgcctttacggaacgcattctccgtggctat
ggcctgaaaactggattctacagctctcctcacctggtgcaggttcgggagcgaatccgt
attaatggtgaacccatcagccccgagctcttcaccaaatacttctggcggctctacaac
cgactggaggagactaaggatggtagctgtgtcagcatgcccccttacttccgcttcctt
accatcatggccttccacgtgttcctccaagagaaggtggacctagctgtggtggaggtg
ggcataggtggtgcttatgactgtaccaacattgtcaggaagccagtggtctgtgggata
tcatctctgggcatagaccatgtcaatatcctgggtgacactattgagaagattgcatgg
cagaaagggggcatctttaagcctggagtcccagctttcactgtgtcccagccagactcc
cccctggaggtgctgaaggaccaagcccgaaagctcatgtgtccgctgtacctgtgtccc
ccactggaggcctttgaggaagaagcccagcccctgcacctggggttggcaggcgatcac
cagcggggcaatgccgccctggctctgcagctggcccgctgctggctccaacaacagggc
cacaagggtattggggagctgaaggccaccaggctgacctcccagcgagccctgccccta
gctcctgtattctatcctaccctgtccatgaagcaggggcttcaggacacagaatggcta
ggccggacacagatgttgagacgaggggccctcacctggtacttggatggggctcacacc
accagcagcattcaggcctcggtgcggtggttccgccgagcggtgctcgaccaggagaag
cttaacaatggccctgaagttcgggttctgctcttcaatgtcactggagaacgagacaca
ggggctctcctcaaactgctgcagccatgccagtttgactacgccgtcttctgccccaac
ctgactgagatgtcttctgtggggaatgcagaccagcagaactttacagtcaccctggac
cacatgctgacacgatgtctggagaaccagaaacagtggaaccagctggcagagcagaag
gcaggcgtggatccctggttggcccaggccccagaacctggcagtggacccctgcatggg
cctcttctcctggtgccccccgctccccggcctcttaacaccaactcccttgtcttcagc
tgcatctcccatgccctgcagtggatcagccagggccgggacccccactttcagccctcc
agccctccccgggggcttcactcccaccctgtggccagcagtggggctgtcctcctcaag
gaagcctcctccatccaggttctggtcactggcagtcttcacctggtgggtggtgtctta
aagctcctcgatcccacactgtcccagtaa
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