Trichosurus vulpecula (common brushtail): 118846485
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Entry
118846485 CDS
T10126
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp01521
EGFR tyrosine kinase inhibitor resistance
tvp01522
Endocrine resistance
tvp01524
Platinum drug resistance
tvp04010
MAPK signaling pathway
tvp04012
ErbB signaling pathway
tvp04020
Calcium signaling pathway
tvp04066
HIF-1 signaling pathway
tvp04151
PI3K-Akt signaling pathway
tvp04510
Focal adhesion
tvp04520
Adherens junction
tvp04530
Tight junction
tvp05200
Pathways in cancer
tvp05205
Proteoglycans in cancer
tvp05206
MicroRNAs in cancer
tvp05212
Pancreatic cancer
tvp05213
Endometrial cancer
tvp05215
Prostate cancer
tvp05219
Bladder cancer
tvp05223
Non-small cell lung cancer
tvp05224
Breast cancer
tvp05226
Gastric cancer
tvp05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118846485 (ERBB2)
04012 ErbB signaling pathway
118846485 (ERBB2)
04066 HIF-1 signaling pathway
118846485 (ERBB2)
04020 Calcium signaling pathway
118846485 (ERBB2)
04151 PI3K-Akt signaling pathway
118846485 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118846485 (ERBB2)
04520 Adherens junction
118846485 (ERBB2)
04530 Tight junction
118846485 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118846485 (ERBB2)
05206 MicroRNAs in cancer
118846485 (ERBB2)
05205 Proteoglycans in cancer
118846485 (ERBB2)
05230 Central carbon metabolism in cancer
118846485 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
118846485 (ERBB2)
05226 Gastric cancer
118846485 (ERBB2)
05219 Bladder cancer
118846485 (ERBB2)
05215 Prostate cancer
118846485 (ERBB2)
05213 Endometrial cancer
118846485 (ERBB2)
05224 Breast cancer
118846485 (ERBB2)
05223 Non-small cell lung cancer
118846485 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118846485 (ERBB2)
01524 Platinum drug resistance
118846485 (ERBB2)
01522 Endocrine resistance
118846485 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tvp01001
]
118846485 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tvp04147
]
118846485 (ERBB2)
04090 CD molecules [BR:
tvp04090
]
118846485 (ERBB2)
Enzymes [BR:
tvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
118846485 (ERBB2)
Protein kinases [BR:
tvp01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
118846485 (ERBB2)
Exosome [BR:
tvp04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
118846485 (ERBB2)
CD molecules [BR:
tvp04090
]
Proteins
118846485 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
ABC1
PDGLE
CcmD
Motif
Other DBs
NCBI-GeneID:
118846485
NCBI-ProteinID:
XP_036610986
LinkDB
All DBs
Position
4:complement(185448509..185478734)
Genome browser
AA seq
1255 aa
AA seq
DB search
MDLSGCCCWGLLLVLLPPAVWGTQVCTGTDMKLQYPASIENHLDTLRHLYQGCQVVQGNL
ELTYLPADANLSFLQDIQEVQGYVLIAHSLVKSFPLQRLRIIRGTQLYEDKYALVVLDNG
NPLGTAPPTPQGLPGLRELQLRSLTEILKGGVLILNNPQLCHQDTVLWTDIFHKNNYLAT
TSIDTNRSRTCSPCSSSCKSGKCWGEGHDNCQSLTSTICASGCARCKGPLPTDCCHEQCA
AGCTGPKHSDCLACLHFNHSGICEQHCPPLVIYNSDTFESMPNPDGRYTFGSSCVKSCPY
NYLATDVGSTSCTLVCPLHSQEVTAEDGTHRCEKCSKACPKVCYGLGMGHLRSVRAVNST
NIQDFAGCKKIFGSLAFLPETFTGDLATNTSPLMPEDLKVFENLEEITGYLYISAWPDSF
PDLSIFQNLRVIRGRVLHNGVYSLTLEHLGIGWLGLRSLRELGSGLALIHHNAHLCFVHT
VPWNQLFRNTRQALLYSANRPADECAREGLACYSLCAQGHCWGPGPTQCLNCSQFLRGQE
CVEECRVMQGYPREYVKERRCFPCHEECQPQNGTETCFGSEADKCVACAHFKDPPACVAR
CPSGVKSDLSFIPIWKYPDDEGICQTCPTNCTHSCTVLDDKGCPAEQKLSPVTSIIAGVV
GVLLALIIGLIIGILIKRRKQKERKHTMRRLLQETELVEPLTPSGALPNQAQMRILKETE
LRKVKVLGSGAFGTVYKGIWIPDGESVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGS
PYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLCSQDLLNWCVQIAKGMNYLEEV
RLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILCRRF
THQSDVWSYGVTVWELMTFGAKPYEGIPAREIPDLLEKGDRLPQPPVCTIDVYMIMVKCW
MIDSECRPRFRELVTEFSRMARDPQRFVVIQNEDSGPASPLDSTFYRSLLEEDDMGDLVD
AEEYLVPQQGFFCPDPPLAPGPGGTAHRRHRSSSTRSGGELPGGLEGSEDDTPQTSTEPW
EGTGSDVFDGDPGGSPKGLQGLPPRDLSPLQRYTEDPTGTLPPEMDGYIVPPVCGPLPEY
VNQPEVHLPPPSPLEGTLTPPHPSSSTLERPKLPPPGKNGVVKDTFTFGAAVENPEYLAP
HGGGPLHLSPTAFSPAFDNLYYWDQDPPDRGAAPNGFAATPTAENPEYLGLDMTV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggacctgtcgggctgctgctgttgggggctccttctggtccttctgcccccagcagtc
tggggaacccaagtgtgcacaggcacagatatgaagctgcagtatcctgccagtattgag
aatcaccttgacacactgagacacctgtaccaaggatgccaggttgtacagggcaacttg
gaactcacttacctgcctgctgatgccaacctctccttcctccaggacatccaggaagtg
caggggtatgtgctgattgcccacagcctggtgaagagcttcccgctgcagaggctacgc
atcatacgaggcacacagctctatgaggacaaatatgccctggttgttctggacaatggg
aatccccttgggactgcccctcccacaccacagggcctccctggccttcgggagctgcaa
cttcgaagcctcacagagattctgaaaggtggggtcctgatcctgaacaaccctcagcta
tgtcaccaggacacagtgctatggaccgacatcttccataagaacaactacttggctacc
acctccatcgacacaaaccgcagccgaacttgcagcccttgttcttcatcatgtaaatcc
ggcaaatgctggggggaaggacatgacaactgtcagagcttgaccagcacaatctgtgcc
agtggctgtgcccgctgcaaggggcccctccccacagactgctgccatgaacagtgtgct
gctggctgcactggccccaagcattctgactgcctggcctgcctccacttcaaccacagt
ggcatctgtgagcagcactgcccaccgctggtcatctacaactcagacacctttgagtca
atgcctaatcctgatgggcgatacacctttgggtccagttgtgtgaaatcatgtccctat
aactacctggctacagacgtgggctccacctcctgcacccttgtgtgtcccctccacagc
caggaggtgactgccgaggatgggacccatcggtgtgagaagtgcagcaaggcctgtccc
aaagtgtgttatgggctgggcatggggcacttgcggtcagtgagagctgtcaacagtacc
aacatccaggactttgccgggtgcaagaagatctttggaagcctggccttcttgcctgaa
accttcacaggggacttggccaccaatacttctccactaatgcctgaagatctcaaggtc
tttgagaacctggaggagatcacaggctatctatacatctcagcctggcctgacagcttc
cctgacctcagcatctttcagaacctaagggtgatcaggggaagggtgctgcacaatggt
gtctactccctgacactggagcatctgggtattggctggctggggctgcggtcactgaga
gagcttggcagtgggctggcactcatccatcacaatgcccacctatgctttgtccacacg
gtgccttggaaccagctcttccgcaatacccgccaggccctactctacagtgccaaccga
cctgctgatgagtgtgcaagggagggactagcatgctactccctgtgtgctcaggggcac
tgctggggccccggaccaactcagtgtctcaactgcagccaatttctccgagggcaggag
tgtgtggaggagtgccgggtcatgcaggggtacccccgagaatatgtaaaggagaggcgc
tgcttcccatgccatgaggagtgccagccacagaatggcactgagacctgctttggatcg
gaggctgacaaatgtgtagcctgtgcacatttcaaggatccccctgcctgtgtggcccga
tgccccagtggggtgaagtctgacctctccttcatacctatctggaagtacccagatgat
gagggcatttgccagacctgccccaccaactgtacccactcctgtactgtattggatgac
aaaggctgtcctgctgagcagaaactcagccctgtgacctccatcattgctggggtggtc
ggggtgctcctagccctcatcataggcctgatcattggcatcttgattaagcgtcggaag
cagaaggaacgcaaacacactatgaggaggctgctacaggagacggagctggtggagccc
ctgacgcccagcggggcattgcccaaccaagctcagatgcgaatcctaaaagagacggag
ctgaggaaagtgaaggttctcggttctggggctttcggcacagtctacaagggtatttgg
atccccgatggtgaaagtgtgaagattccagtggctatcaaggtgttgagggaaaacaca
tcccccaaagccaacaaggagatcttggatgaagcatacgtgatggcaggtgtcggctct
ccatatgtgtctcgccttctgggcatctgtctgacatctacggtgcagctggtgacccag
cttatgccctatggctgcctcctggaccatgtgcgtgaaaaccgagggcgactctgctcc
caggacctcctcaattggtgtgtgcagattgccaaggggatgaactacctggaggaggtt
cggctagtacacagagacctagcagccagaaatgtgctggtcaaaagtcccaaccacgtc
aagattaccgactttggactcgcaaggctcttggacattgatgagacagagtaccacgca
gatgggggcaaggttcccatcaagtggatggcactggagtccattctctgccgaagattc
acccatcagagtgatgtgtggagctatggggtgacagtgtgggaactgatgacctttggg
gctaaaccatatgaggggattcctgcccgagagattcctgacctgctggagaaaggggac
cgactgccccagccccccgtctgcaccatcgatgtctacatgatcatggtcaaatgttgg
atgattgactctgagtgtcggcctcggttccgggagctagttactgaattctcacgaatg
gcccgagaccctcagcgctttgtggtcatccagaatgaggattctggcccagccagcccc
ctggacagcactttctaccgctcactgttggaagaagacgacatgggagacttggtggat
gcagaagaatacctggtgccccagcaaggcttcttctgccctgaccctcccctggctcca
ggtcctgggggcactgcccacagaagacacagaagttcttctacaaggagtggcggggag
cttccaggcggactggaaggctcagaagatgacactccccaaacttcaacagagccttgg
gaagggactggttcagatgtgtttgatggggaccctggagggagccctaaggggctacag
gggctcccccctcgagacctcagccccctgcagcgctacactgaggatcccacagggaca
ctgccccctgagatggatggctacattgtcccacctgtctgtggccccctgccagaatac
gtgaaccagccagaggtgcacctaccacccccttcacctctggaggggaccctgactccc
cctcacccatccagctccaccctggaacgccccaagttgcctcctccagggaagaacgga
gtggtgaaggacacatttacctttggtgcagctgtggagaaccctgagtacttggcccca
catggaggcggtccccttcatctttccccaactgccttcagcccagcctttgacaacctc
tactactgggaccaggatccccctgaccgaggggctgctcctaatggctttgcagcgacc
cccacagctgagaaccctgagtacttgggtctggatatgactgtgtga
DBGET
integrated database retrieval system