Trichosurus vulpecula (common brushtail): 118846502
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Entry
118846502 CDS
T10126
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00230
Purine metabolism
tvp00670
One carbon pool by folate
tvp01100
Metabolic pathways
tvp01523
Antifolate resistance
Module
tvp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118846502 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118846502 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118846502 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tvp04147
]
118846502 (ATIC)
Enzymes [BR:
tvp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
118846502 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
118846502 (ATIC)
Exosome [BR:
tvp04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118846502 (ATIC)
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GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
TIP39
Motif
Other DBs
NCBI-GeneID:
118846502
NCBI-ProteinID:
XP_036611009
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Position
4:complement(285418302..285456908)
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AA seq
592 aa
AA seq
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MASRQLALLSVSDKTGLLDFARNLKSVGLMLVASGGTAKALRDAGLDVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNSLEDQADMATLDFSLIRVVVCNLYPFVKTVASPNVTVDEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPGDYEVVSTEMLNSEAKDTTMETRRQLALKAFT
HTAEYDQAISDYFRKEYSKGISQIPLRYGMNPHQTPAQLYTVKPRLPLTVLNGSPGFINL
CDALNAWQLVRELREALGIPAATSFKHVSPAGAAVGIPLSEEEAKVCMVHDLYKSLTPLS
TAYARARGADRMSSFGDFIAISDACDVTTAKIISREVSDGIIAPGYEEEALKILSKKKNG
NYCVLQMDPCYKPDEDEIRTLFGLHLSQKRNNGVVDKSLFSNVVTKHKDLPEFAVRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGEKANNWWLRHHPRVLSMKFKA
GIKRAEISNAIDQYVTGTIGEDDDLAKWEAMFEEVPKLLTEVEKKEWIDSFKQVSLSSDA
FFPFRDNIDRAKRSGVEFIVAPSGSAADQNVIEACDELGIILVHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcctcccgccagctcgccttgttgagtgtctctgacaagacaggactgttggacttt
gccagaaatctgaaatcggttggtttgatgctggttgcttctggagggacagcaaaagct
ctgagagatgctggtctggatgtcagggatgtttctgaactgacaggattcccagaaatg
ttaggaggacgtgtgaaaacactgcatcctgcagttcatgctggtatcttggctcgtaat
tctctggaagatcaagctgacatggccacacttgacttcagtcttataagagttgttgtt
tgtaatctatatccctttgtgaagactgtggcttctccaaatgtaactgttgatgaagct
gttgaacaaattgatattggtggagtaaccttacttagagctgctgcaaaaaaccatgct
cgagtgacagtagtatgtgaaccaggagattatgaagtggtatcaactgagatgctaaac
tctgaagctaaagatactactatggagactagacggcagctagcattaaaggcctttact
catactgctgagtatgatcaagcaatatcagattatttcaggaaggaatatagtaaagga
atatctcagattcctttaagatacggaatgaaccctcaccagacccctgcacagttatat
acagtgaagcccagacttcctcttacagttctgaatggatcccctgggtttataaaccta
tgtgatgccttgaatgcctggcagctagtgagagaactcagagaagctctaggcattcca
gcagctacctccttcaagcatgtcagtccagcaggtgctgctgttggaataccacttagt
gaggaagaggctaaagtttgcatggttcatgatctctacaagagccttactccattgtca
actgcatatgcaagagcaagaggagctgatagaatgtcatcatttggtgactttattgct
atatctgatgcttgtgatgtcactactgctaaaatcatctccagagaggtatctgatggt
attattgcacctggatatgaagaggaagccttgaagatcctctccaaaaagaaaaatggg
aattactgtgtacttcagatggacccatgttataaaccggatgaggatgagattcgaact
ctttttggattacatctaagtcagaagaggaataatggtgttgtggacaagtcattgttt
agcaatgttgttacaaagcataaagatttgcctgagtttgctgtcagggacctcatcgta
gctacgattgctgtcaagtatactcagtccaattcagtgtgttatgctaagaatggtcag
gtaattggtattggagcaggtcagcaatccagaatacactgtacacgccttgcaggagag
aaggcaaataattggtggcttagacatcaccccagggtgctttcaatgaaatttaaagct
ggaataaagagagcagaaatctctaatgctattgatcaatatgtgactggcaccattggt
gaggatgatgatttggccaaatgggaagcaatgtttgaggaagttcctaaacttttaact
gaggtagaaaagaaggaatggattgattcattcaaacaagtatctctcagctccgatgcc
tttttcccttttagggataatatagacagggctaagaggagtggtgtagagttcatcgtg
gccccctcaggttcagctgctgaccagaatgtgattgaggcctgtgatgagcttggaata
atactcgttcatacaaaccttcgactgtttcatcattga
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