Trichosurus vulpecula (common brushtail): 118847444
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Entry
118847444 CDS
T10126
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp04140
Autophagy - animal
tvp04141
Protein processing in endoplasmic reticulum
tvp04210
Apoptosis
tvp04932
Non-alcoholic fatty liver disease
tvp05010
Alzheimer disease
tvp05012
Parkinson disease
tvp05014
Amyotrophic lateral sclerosis
tvp05016
Huntington disease
tvp05017
Spinocerebellar ataxia
tvp05022
Pathways of neurodegeneration - multiple diseases
tvp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
118847444 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118847444 (ERN1)
09143 Cell growth and death
04210 Apoptosis
118847444 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118847444 (ERN1)
05012 Parkinson disease
118847444 (ERN1)
05014 Amyotrophic lateral sclerosis
118847444 (ERN1)
05016 Huntington disease
118847444 (ERN1)
05017 Spinocerebellar ataxia
118847444 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
118847444 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118847444 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118847444 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tvp01001
]
118847444 (ERN1)
Enzymes [BR:
tvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118847444 (ERN1)
Protein kinases [BR:
tvp01001
]
Serine/threonine kinases: Other
IRE family
118847444 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
118847444
NCBI-ProteinID:
XP_036611815
LinkDB
All DBs
Position
4:complement(197199264..197332538)
Genome browser
AA seq
980 aa
AA seq
DB search
MPVPLRRLLQLLALLLLPLPGPGSFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSTKWT
LKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGI
LYMGKKQDIWYVVDLMTGEKQQTLSSAFAESLCPSTSLLYLGRTEYTITMYDTKSRELRW
NATYFDYAATVPEEDMEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWHRE
GLQKVMHTNVGVETLRYLTFMSGEVGRITKWKYPFPKETETKSKLTPTLYVGRYSTSLYA
SPSMVHEGVAIVPRGSAFPQLEGPQTDGVTIKSNEECVITPSVDLNIDFGIKGKNKLNYW
TNYWLLIGHHEIPLSASTTVLEKFPNKLPRHRENVIHADSEKSFEEKVIKIVDRDAEEPT
PTAHQDIEFTRTPVKTEAAVDSMLKDMATIILCTFLLIGWVAFVITYPMSMHQQQQLQHQ
QFQRQLEERIQLLQQQQLPFQPPSDLAQDPDLLDASAGLHSESSAPSSPNMSPKGSNHSQ
HSSNSASKVGSSTVAEQDDDDEETSVVVVGKISFCPKDVLGHGAEGTIVYRGMFDNRAVA
VKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKD
FAHLGLEPITLLQQTTSGLAYLHSLSIVHRDLKPHNILLSMPNAHGKIKAMISDFGLCKK
LAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISDGNHPFGK
SLQRQANILLGAYSLDCLHPEKHEDIVAHELIEKMIAMDPQKRPSAQHVLKHPFFWGLEK
QLQFFQDVSDRIEKEALDGPIVKQLEKGGRRVVKMDWRENITVPLQTDLRKFRTYKGGSV
RDLLRAMRNKKHHYRELPEAVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCSQERLF
QPYYFQEATELGPTVTNDGL
NT seq
2943 nt
NT seq
+upstream
nt +downstream
nt
atgccggtcccgctgcgccggctcctgcagctgctggcgctgctgctcttgcccctgccc
ggtcccgggagttttggaagtaccagcactgtgaccctccccgagaccctgttgtttgtt
tccactttggatggaagtctgcacgctgtgagcaagagaacgggctcgaccaaatggact
ttaaaagaagatccagtcctgcaggttcccacccatgttgaagagcctgcattcctccca
gaccccaatgatggaagcttgtatacacttggtggtaagaacaacgaaggtctgacgaaa
cttccctttaccatcccagaattggtgcaggcatctccatgccgaagttcagatggcatt
ctctacatgggtaaaaagcaggatatttggtacgtcgttgaccttatgactggagagaag
cagcagactttgtcctccgcatttgcagaaagcctctgtccatccacctctcttctgtat
ctcggacgaacagagtacaccatcaccatgtatgatacaaagagccgagagcttcggtgg
aatgctacctattttgactatgcggccactgtaccagaagaagacatggagtacaagatg
tcccacttcgtgtccaatggggacgggctggtggtgaccgtggacagcgagtctggagat
gtcctgtggattcagaattacgcctcgccggtggtggccttctacatctggcaccgggag
ggtctgcagaaggtgatgcacaccaacgtcggggtggagacgctgcgctatctgaccttc
atgtctggagaggtggggcgtatcaccaagtggaaataccccttcccaaaggagaccgag
accaagagcaaactgacgcccaccctctatgttgggagatattccaccagcctgtatgcc
tccccatcaatggtccatgaaggagttgctattgtgcctcgaggcagtgcctttccccaa
ctagaaggcccccagacagatggcgtcacaatcaaaagtaatgaagaatgtgtgatcacc
cccagcgtagacctgaacattgattttggaatcaaaggaaaaaataaactcaactactgg
accaattattggcttctcataggacatcatgagatccccctctccgcttctaccacagtc
ttggagaaattccccaacaaactgcccagacatcgtgaaaatgtgatccatgccgattca
gagaagagttttgaggagaaggttatcaaaatagttgaccgggacgcagaagaaccaact
cctaccgctcatcaagatattgaattcactcgaaccccagtaaaaacagaggcagcggtg
gactccatgttgaaggacatggctacaatcatcctgtgtaccttccttcttattggatgg
gtcgcctttgtcatcacctacccaatgagcatgcaccagcaacagcagctccagcaccag
caatttcagaggcagctggaagagaggatccagctgctgcagcaacagcagcttcctttc
caacctcccagtgacctggctcaggacccggacttgctggatgcctctgctggtttgcac
tctgagagctcagcccccagcagtcccaacatgtcccccaagggctccaaccactctcag
cattccagcaactcagcgtccaaggtcggcagcagcactgtcgctgagcaagatgatgac
gatgaagagaccagcgtggtggtggttgggaaaatttccttctgcccaaaggatgtctta
ggacatggagctgaaggcacaatcgtataccgggggatgtttgacaaccgggctgtggca
gtaaagaggatactcccagagtgcttcagttttgcagaccgtgaggtgcagctgcttcgg
gaatcagacgagcaccccaatgtgattcgctatttctgcacggagcgagatcgccagttc
caatatattgctattgaactgtgtgcagccactttgcaagagtacgtggaacagaaggac
tttgctcaccttggcttagaacccatcaccttgttgcagcagacaacatcgggacttgct
tatcttcactccctcagcattgttcacagagacctgaaaccccacaacatcctcctctcc
atgcccaatgcacatggcaagatcaaggctatgatctctgactttggcctctgcaagaag
ctggcggtgggtaggcacagtttcagccgccgctccggggtaccaggcactgagggatgg
attgccccagagatgctgagcgaggattgcaaggagaatccgacttacacagtggacatt
ttctctgcgggttgtgtcttttactatgtgatatctgatggcaaccacccatttggcaag
tccctgcagcggcaagccaacatcctccttggtgcctacagccttgactgtttgcaccca
gagaagcatgaagacatcgttgctcatgaactaatagaaaaaatgattgctatggatcct
cagaagcggccctcagcccagcacgtgctgaaacacccattcttctggggcttagaaaag
cagctgcagttttttcaggacgtgagtgaccggatcgagaaggaggccttagatggtccc
atagtgaagcaattagaaaaaggagggagaagagtggtcaaaatggactggagggaaaac
attactgttccgctccagacagatcttcgaaaattcagaacctataaaggaggttctgta
agagatcttctccgtgctatgagaaataagaagcaccactaccgggagctccctgaggct
gtgcaggagacactgggctctatccctgatgattttgtccgttatttcacatcacggttc
ccccacctcctctcccacacctaccgagccatggaactatgtagccaggagaggctcttt
cagccttactatttccaagaggccacagaactgggccccacagtgacaaacgatggcctc
tga
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