Trichosurus vulpecula (common brushtail): 118847807
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Entry
118847807 CDS
T10126
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp01521
EGFR tyrosine kinase inhibitor resistance
tvp04151
PI3K-Akt signaling pathway
tvp04217
Necroptosis
tvp04380
Osteoclast differentiation
tvp04550
Signaling pathways regulating pluripotency of stem cells
tvp04620
Toll-like receptor signaling pathway
tvp04621
NOD-like receptor signaling pathway
tvp04630
JAK-STAT signaling pathway
tvp04658
Th1 and Th2 cell differentiation
tvp04659
Th17 cell differentiation
tvp05140
Leishmaniasis
tvp05145
Toxoplasmosis
tvp05152
Tuberculosis
tvp05160
Hepatitis C
tvp05161
Hepatitis B
tvp05162
Measles
tvp05163
Human cytomegalovirus infection
tvp05164
Influenza A
tvp05165
Human papillomavirus infection
tvp05166
Human T-cell leukemia virus 1 infection
tvp05167
Kaposi sarcoma-associated herpesvirus infection
tvp05168
Herpes simplex virus 1 infection
tvp05169
Epstein-Barr virus infection
tvp05171
Coronavirus disease - COVID-19
tvp05200
Pathways in cancer
tvp05203
Viral carcinogenesis
tvp05212
Pancreatic cancer
tvp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118847807 (JAK1)
04151 PI3K-Akt signaling pathway
118847807 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
118847807 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
118847807 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
118847807 (JAK1)
04621 NOD-like receptor signaling pathway
118847807 (JAK1)
04658 Th1 and Th2 cell differentiation
118847807 (JAK1)
04659 Th17 cell differentiation
118847807 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
118847807 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118847807 (JAK1)
05203 Viral carcinogenesis
118847807 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118847807 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
118847807 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
118847807 (JAK1)
05161 Hepatitis B
118847807 (JAK1)
05160 Hepatitis C
118847807 (JAK1)
05171 Coronavirus disease - COVID-19
118847807 (JAK1)
05164 Influenza A
118847807 (JAK1)
05162 Measles
118847807 (JAK1)
05168 Herpes simplex virus 1 infection
118847807 (JAK1)
05163 Human cytomegalovirus infection
118847807 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
118847807 (JAK1)
05169 Epstein-Barr virus infection
118847807 (JAK1)
05165 Human papillomavirus infection
118847807 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
118847807 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
118847807 (JAK1)
05140 Leishmaniasis
118847807 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118847807 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tvp01001
]
118847807 (JAK1)
Enzymes [BR:
tvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118847807 (JAK1)
Protein kinases [BR:
tvp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118847807 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
118847807
NCBI-ProteinID:
XP_036612329
LinkDB
All DBs
Position
4:14535419..14697304
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNFKEDCNAMAFCAKMRSYKKNEVNLDVLEPGVEVVFYLPDRKPLHLLSGEYTVEDL
CIRAAQECCISPLCHNLFALYDEKTKLWYAPNHCIKIEEKTSLRLHYRMRFYFTNWHGTN
ENEQSVWRHSPKKQKNGYERRRVLDATPLLDANSLEYLFAQGQYDLVKCLAPVRDPKTDQ
EVHEIENECLGMAVLAISHYAMMNNIQLPDLPKDVSYKRYIPETLNRTIRQRNPLTRIRI
NHVFKDFLKEFNNKTICDSSVTPHDLKVKYLSTLETLTKHYGAEIFETSLLLISSENEMN
KLNSKDCGNVIRYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKQESKHRKDEEKNKAR
EEWTNFSYFPEITHVVIKESVVSINKQDNKKMELSLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIENGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CLEKSEQMLTSQKQYKNFQIEVKKGKYSLHGSDRVFPSLRGLMDHLKKQILKTDNISFVL
KKCCQPKPREISNLLVATKKAQECLPVYTMSQLSFHRILKEDIIQGEHLGRGTRTQIYSG
TLDYKDEEGSSDEKKMKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFMEFGPLDLFMHKKSELLTTPWKFKVAKQLASALSYLEDKDLVHGNVCAKNVL
LAREGLDGDCSPFIKLSDPGIPITVLSRQECVERIPWIAPECVDDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLAEKERFYEGRVMPVTPSCKELADLMTQCMNYDPSQRPFFRAI
MRDINKLEEQNPDILSEKQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNQIADLKKEIEILKNLYHENIVKYKGICTEDGGNRIKLIMEFLPS
GSLKEYLPRNKNKISLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVENEHRVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLVQCKFYIASDVWSFGVTLHELLTYCDSE
SSPMAMFLKMIGPTQGQMTVTRLVRALKDGKRLQCPPNCPEEVYQLMKKCWEYQPNNRTS
FQNLIRGFEALIK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatttcaaagaggactgcaatgccatggcgttctgtgcaaaaatgagg
agctacaaaaaaaatgaggtgaatctggatgtgctggagcctggagtggaggtggtgttc
tatctgcctgataggaagcccctccacttgctcagtggggagtacaccgtagaagacctg
tgtatcagagctgcacaggagtgctgtatatctccactgtgccacaacctctttgccctg
tatgatgagaagaccaagctgtggtacgccccaaatcactgcatcaagattgaagagaaa
acatcgctgcggctacattatcgaatgagattctatttcaccaattggcatgggaccaat
gagaatgagcagtcggtgtggagacactccccaaagaagcaaaaaaatggctacgaaaga
agacgggtccttgatgccacacccctcctcgatgccaattcactggagtatctctttgct
cagggacaatatgatttggtgaagtgcttggctcctgtacgagacccaaagactgatcag
gaagtgcatgagattgaaaatgagtgtctggggatggcagtgctggccatatcccattac
gccatgatgaataacatacaacttccagacctgccgaaggatgtcagttacaaacgatat
attccagaaacactgaacaggaccatcagacaaaggaatcccttaacgagaatacgaata
aatcatgttttcaaggatttccttaaggaatttaacaacaagaccatttgtgacagtagc
gtgactcctcatgatctgaaggtgaaatacctgtcaactttggagactctaaccaaacat
tatggagcggagatttttgagacttcactcttgttgatttcatctgaaaatgaaatgaat
aaattaaattctaaagactgtgggaacgtcatacgttatgaagtgatggtgactggaaat
cttggaatacagtggaggcaaaaaccaaatgtggttcctgttgagaaggagaaaaataag
ctgaagaggaagaagcaggaaagcaaacacaggaaagatgaggagaagaacaaagctcgg
gaggaatggaccaacttctcttatttccctgaaatcacccatgttgtcatcaaggaatcc
gtggtcagcattaacaagcaagacaacaagaagatggagttaagcctgtcttcccacgag
gaagccttgtccttcgtgtctctggtggacgggtatttccgactcacggcagatgcccat
cattacctctgcacagatgtcgctcctccgctgattgtgcacaacatagaaaatggctgc
catgggcccatctgtactgagtatgcaatcaacaagctgagacaagaaggaagcgaggaa
ggcatgtacgtcttgcgctggagctgcacagactttgataacatcctcatgaccgtgacc
tgcttggagaaatcagagcagatgttgacgagccagaaacagtacaagaatttccagatt
gaagtgaagaaggggaaatactccctgcatggttccgatcgagtgttcccctccctcaga
ggcctgatggaccatctcaaaaagcagatcctgaaaacagacaacatcagctttgtcctg
aagaaatgctgccagccgaaaccgagagaaatttctaatctgcttgtggccaccaagaag
gcccaggaatgcttgccagtctacacaatgagccagctgagtttccatcgaattctcaag
gaagacatcattcagggagagcacctgggacgaggcactcggacccagatctactcaggg
accctggactacaaggatgaggaaggcagctctgatgagaaaaagatgaaagtgatcctg
aaagtcttggaccccagccacagggacatttctctggctttcttcgaggcggccagcatg
atgagacaagtctcccacaaacacatcgtgtacctctatggcgtctgtgtacgagatgtg
gaaaacatcatggtggaggaatttatggaatttgggcctctggatctcttcatgcataag
aaaagtgaactgctcaccacaccgtggaaatttaaggttgccaaacaactggccagtgca
ctgagttacttggaagacaaagatttggtccatgggaatgtatgtgccaaaaatgtcctc
ttggccagagagggcctggatggtgactgcagccccttcatcaagctcagtgatcctggg
atccccattaccgtgctctctcgacaggagtgtgtggaacggatcccatggattgcacca
gagtgtgtggatgattccaagaacctgagcgtggctgctgataaatggagttttggcaca
accctctgggagatctgttacaatggagaaatccccttgaaagataagacgctagcagag
aaagagcgattttatgaaggtcgagttatgccggtcacgccctcgtgcaaggagctggct
gacctgatgactcagtgtatgaactacgaccctagtcagagacccttcttccgagccatc
atgagagatatcaataagctagaagaacaaaaccctgatattctttcagagaaacaacca
acaactgaggtagatcccacccattttgaaaaacggttcttgaagaggatccgtgacctg
ggagagggccactttgggaaagttgaactctgcaggtatgaccccgagggagacaacact
ggtgagcaggttgcggtcaagtctctgaagccagagagtgggggcaaccagatagccgac
ctgaagaaggagatcgaaatcttgaagaacctttatcatgaaaacattgtgaaatacaaa
gggatttgtacagaggatggagggaataggattaagcttattatggagttcctgccttct
gggagccttaaggaatatcttcctagaaacaagaacaaaatcagcctcaaacagcagctg
aagtacgcggttcagatttgtaaggggatggactatctggggtcccgtcagtatgtccac
cgagatctggcagcaagaaatgtgcttgttgaaaatgagcaccgtgtcaagattggagat
tttggtttaacgaaagccatcgaaacagacaaggagtactacacggtgaaagatgataga
gacagccctgtcttctggtatgctccagaatgtttagttcagtgcaaattttatatcgcc
tccgatgtctggtcgtttggggtcacgttacatgaactcctcacctactgtgattcggaa
tccagtcccatggcgatgttcttaaagatgatcggcccaactcaaggccagatgaccgtc
acaaggcttgtgcgtgcattaaaggatggaaaacgtctgcagtgtccacctaactgccca
gaagaggtttaccaactgatgaaaaaatgctgggagtaccaaccaaacaatcgaacatcc
tttcagaacctcattcgtggatttgaagcacttataaaataa
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integrated database retrieval system
