KEGG   Trichosurus vulpecula (common brushtail): 118851839
Entry
118851839         CDS       T10126                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp01522  Endocrine resistance
tvp04010  MAPK signaling pathway
tvp04015  Rap1 signaling pathway
tvp04068  FoxO signaling pathway
tvp04071  Sphingolipid signaling pathway
tvp04114  Oocyte meiosis
tvp04148  Efferocytosis
tvp04218  Cellular senescence
tvp04261  Adrenergic signaling in cardiomyocytes
tvp04370  VEGF signaling pathway
tvp04380  Osteoclast differentiation
tvp04517  IgSF CAM signaling
tvp04550  Signaling pathways regulating pluripotency of stem cells
tvp04611  Platelet activation
tvp04613  Neutrophil extracellular trap formation
tvp04620  Toll-like receptor signaling pathway
tvp04621  NOD-like receptor signaling pathway
tvp04622  RIG-I-like receptor signaling pathway
tvp04625  C-type lectin receptor signaling pathway
tvp04657  IL-17 signaling pathway
tvp04658  Th1 and Th2 cell differentiation
tvp04659  Th17 cell differentiation
tvp04660  T cell receptor signaling pathway
tvp04664  Fc epsilon RI signaling pathway
tvp04668  TNF signaling pathway
tvp04670  Leukocyte transendothelial migration
tvp04714  Thermogenesis
tvp04722  Neurotrophin signaling pathway
tvp04723  Retrograde endocannabinoid signaling
tvp04728  Dopaminergic synapse
tvp04750  Inflammatory mediator regulation of TRP channels
tvp04912  GnRH signaling pathway
tvp04914  Progesterone-mediated oocyte maturation
tvp04917  Prolactin signaling pathway
tvp04926  Relaxin signaling pathway
tvp04932  Non-alcoholic fatty liver disease
tvp04933  AGE-RAGE signaling pathway in diabetic complications
tvp04935  Growth hormone synthesis, secretion and action
tvp04936  Alcoholic liver disease
tvp05014  Amyotrophic lateral sclerosis
tvp05020  Prion disease
tvp05022  Pathways of neurodegeneration - multiple diseases
tvp05132  Salmonella infection
tvp05133  Pertussis
tvp05135  Yersinia infection
tvp05140  Leishmaniasis
tvp05142  Chagas disease
tvp05145  Toxoplasmosis
tvp05152  Tuberculosis
tvp05161  Hepatitis B
tvp05163  Human cytomegalovirus infection
tvp05167  Kaposi sarcoma-associated herpesvirus infection
tvp05169  Epstein-Barr virus infection
tvp05170  Human immunodeficiency virus 1 infection
tvp05171  Coronavirus disease - COVID-19
tvp05205  Proteoglycans in cancer
tvp05208  Chemical carcinogenesis - reactive oxygen species
tvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tvp05415  Diabetic cardiomyopathy
tvp05417  Lipid and atherosclerosis
tvp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118851839 (MAPK12)
   04015 Rap1 signaling pathway
    118851839 (MAPK12)
   04370 VEGF signaling pathway
    118851839 (MAPK12)
   04668 TNF signaling pathway
    118851839 (MAPK12)
   04068 FoxO signaling pathway
    118851839 (MAPK12)
   04071 Sphingolipid signaling pathway
    118851839 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    118851839 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118851839 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118851839 (MAPK12)
   04218 Cellular senescence
    118851839 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118851839 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118851839 (MAPK12)
   04613 Neutrophil extracellular trap formation
    118851839 (MAPK12)
   04620 Toll-like receptor signaling pathway
    118851839 (MAPK12)
   04621 NOD-like receptor signaling pathway
    118851839 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    118851839 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    118851839 (MAPK12)
   04660 T cell receptor signaling pathway
    118851839 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    118851839 (MAPK12)
   04659 Th17 cell differentiation
    118851839 (MAPK12)
   04657 IL-17 signaling pathway
    118851839 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    118851839 (MAPK12)
   04670 Leukocyte transendothelial migration
    118851839 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118851839 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    118851839 (MAPK12)
   04917 Prolactin signaling pathway
    118851839 (MAPK12)
   04926 Relaxin signaling pathway
    118851839 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    118851839 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118851839 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    118851839 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    118851839 (MAPK12)
   04722 Neurotrophin signaling pathway
    118851839 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118851839 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118851839 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    118851839 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118851839 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    118851839 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118851839 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118851839 (MAPK12)
   05161 Hepatitis B
    118851839 (MAPK12)
   05171 Coronavirus disease - COVID-19
    118851839 (MAPK12)
   05163 Human cytomegalovirus infection
    118851839 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118851839 (MAPK12)
   05169 Epstein-Barr virus infection
    118851839 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118851839 (MAPK12)
   05135 Yersinia infection
    118851839 (MAPK12)
   05133 Pertussis
    118851839 (MAPK12)
   05152 Tuberculosis
    118851839 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118851839 (MAPK12)
   05140 Leishmaniasis
    118851839 (MAPK12)
   05142 Chagas disease
    118851839 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118851839 (MAPK12)
   05020 Prion disease
    118851839 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    118851839 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118851839 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    118851839 (MAPK12)
   05415 Diabetic cardiomyopathy
    118851839 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118851839 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    118851839 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118851839 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118851839 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tvp01001]
    118851839 (MAPK12)
Enzymes [BR:tvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118851839 (MAPK12)
Protein kinases [BR:tvp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118851839 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH RIO1 Kdo Kinase-like Haspin_kinase
Other DBs
NCBI-GeneID: 118851839
NCBI-ProteinID: XP_036617302
LinkDB
Position
5:303465586..303482848
AA seq 364 aa
MSSPPPPRKGFYRQEVTKTAWEVRELYRDLQPVGSGAYGAVCSAIDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDDTLDDFTDFYLVMPFMGTDLSKLM
KHEKLSDDRIQFLVYQILRGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQTDS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKILFKGSDHLDQLMEIMK
VTGTPPPEFVQRLQSQDAKSYMESLPELEKKDFASILTNATPLAVNLLEKMLVLDAEKRV
TAAEALTHPYFETVHESEEEPQAQLYDDSLDDVDLTLDEWKRVTYKEVLSFKPPRLLDSK
ETSL
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgagctcccctccgcccccccggaagggcttttaccggcaggaggtcactaagactgcg
tgggaggtgcgggaactctaccgggacctgcagccagtgggttcgggggcttacggggcc
gtgtgctcggccattgacagcaggaccggcaccaaggtggccatcaagaagctgtaccga
cccttccagtcggagctgttcgccaagcgcgcatatcgggagctgcggctgctcaaacac
atgcggcacgagaatgtgatcggcttgctggacgtcttcacccctgatgacacactggac
gacttcacagacttttacctggttatgccattcatgggcacagaccttagcaagctgatg
aagcatgaaaagctcagtgatgatcgcatccaattcttggtctaccagatccttcgaggc
ctcaagtacatccatgctgctggcatcatccacagggatctcaaacctggtaacctggct
gtgaatgaggactgtgagctgaagattctggactttggcctggccagacagacagacagt
gagatgaccggctatgtggttaccagatggtaccgggcaccggaggtcatccttaactgg
atgcattacacacagacagtggatatctggtctgtgggctgcatcatggcagagatgatc
actggcaagatccttttcaaaggcagcgatcacctggaccagctgatggagatcatgaaa
gtgactgggacgcctcccccagagtttgtacagcgtcttcagagtcaggatgcaaagagc
tacatggaaagtctccccgagctggagaagaaggactttgcttccatcctgacgaatgca
acccccttggctgtgaacctgctggagaagatgttggtactggacgccgagaagcgagtg
acagcagccgaggctctgactcacccatactttgagactgtgcatgagtccgaggaggag
ccacaggcccagctgtacgatgactccttggatgacgtcgacctgacgctggatgagtgg
aaacgagtcacatacaaagaagttctcagctttaagcctcctcggctcctggactcaaag
gaaacatctctgtga

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