Trichosurus vulpecula (common brushtail): 118853358
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Entry
118853358 CDS
T10126
Symbol
HMGCR
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
KO
K00021
hydroxymethylglutaryl-CoA reductase (NADPH) [EC:
1.1.1.34
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00900
Terpenoid backbone biosynthesis
tvp01100
Metabolic pathways
tvp04152
AMPK signaling pathway
tvp04976
Bile secretion
Module
tvp_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
Enzymes [BR:
tvp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
118853358 (HMGCR)
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NCBI-GeneID:
118853358
NCBI-ProteinID:
XP_036619275
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Position
1:complement(441733438..441761073)
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AA seq
884 aa
AA seq
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MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNDKICGWNYECPKFEEDVLSS
DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
LNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSSQNSTAENSKVALGLDENVSKR
IEPNVSLWQFYLSKMISMDIEQMITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVMI
QKKAPDTCCRREPVLARNKQKFSEMEEESGHNKERKAEVIKPLLAETETSKVTFVLGNSA
AHPTSSNTEPEIELPTEPRPNEECLQILENIEKGAKFLSDAEIIRLVNAKHIPAYKLETL
METHERGVSIRRQMLSKKLPEPSSLEYLPYRDYNYSLVMGACCENVIGYMPVPVGVAGPL
SLDGKEFQVPMATTEGCLVASTNRGCRAICLGGGASSCVLADGMTRGPVVRFPSACDSAK
MKTWLESPEGFKIIKEAFDSTSRFARLQKVHISLAGRNAYIRFQSRTGDAMGMNMISKGT
EKALAKLHEVFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREVLKTT
TEALVEVNISKNLVGSAMAGSIGGYNAHAANIVTAIFIACGQDAAQNVCSSNCITLMEAT
GPLNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAKIVCG
TVMAGELSLMAALAAGHLVKSHMIHNRSKVNLQNLQGTCTKKVA
NT seq
2655 nt
NT seq
+upstream
nt +downstream
nt
atgttgtcaagactcttccgaatgcatggcctctttgtggcatcccatccttgggaagtc
atagtgggcactgtgactcttaccatctgcatgatgtccatgaacatgtttactggtaat
gacaaaatctgtggctggaattatgaatgtccaaagtttgaagaagatgttttaagcagt
gatattatcattctgacaatcacacgatgcatagcaatcctgtatatttactttcagttc
cagaatctaagacagcttggatcaaaatatattttgggcatcgccggcctttttaccatc
ttctcaagctttgtcttcagcacagttgttattcatttcttagataaagagttgacgggc
ctgaatgaagctctgcccttttttctgctcttgattgacctttcccgagccagtgcttta
gcaaagtttgccctcagttctaactcacaggatgaagtaagagaaaacattgcccgtgga
atggcaatcttaggcccaactttcacactcgatgcccttgtcgaatgtcttgtgattggt
gttggtaccatgtctggtgttcgacaacttgaaattatgtgctgctttggttgcatgtca
gtccttgccaattactttgtgttcatgacattctttccagcttgtgtatctttggtatta
gagctgtctcgggaaagtcgtgaaggtcgtccaatatggcaactcagtcattttgcccgt
gttttagaagaagaagaaaataaaccaaatcctgtaactcagcgggtcaagatgattatg
tctctaggcttggttcttgttcatgctcatagtcgctggatagctgatccatcatctcag
aacagtaccgccgaaaattctaaggttgctttaggactggatgaaaatgtgtccaaaaga
attgaacctaatgtttctctctggcagttttatctttctaagatgatcagtatggacatt
gaacaaatgatcacccttagtttagctctccttctggctgtcaagtacatcttctttgaa
caggcagaaacagagtctacactgtcattaaaaaaccccatcacgtctcctgtgatgatt
caaaagaaggctccagacacctgttgtagacgggaacctgtgttggccagaaataagcag
aaattcagtgaaatggaagaagaatctgggcataacaaggagagaaaagctgaagttata
aagcccttattggcagaaactgaaacatcaaaggttacatttgttttgggtaactcagct
gcacatccaacatcatcgaacactgagcctgaaatcgaactacccactgaaccacgtcct
aatgaagaatgtctccagatacttgaaaatatagagaaaggtgcaaaattcctcagtgat
gctgagatcatcagattagtcaatgctaagcatattccagcttataaattggaaactttg
atggaaacccatgagcgaggtgtgtctattcgccgacaaatgttgtctaagaagcttcct
gaaccctcttcattagagtatttaccatacagggattataattattctttggtgatgggg
gcatgctgtgagaatgttattggatacatgcctgttcccgttggagtagccgggcccctc
tctctggatggcaaagaattccaggtcccaatggccacaactgaaggctgtcttgtagcc
agtaccaacaggggttgtagagcaatatgtcttggtggaggagcaagtagctgtgttctg
gcagatgggatgactcgagggccagtagtaaggtttcccagcgcatgtgactctgcaaag
atgaagacttggcttgaaagtcctgaaggctttaagataataaaggaagcgtttgacagc
accagcaggtttgcgcgtcttcagaaagttcacattagtctggctggtcggaatgcctat
atccgtttccaatccaggacaggggatgccatgggaatgaatatgatttcaaagggaaca
gagaaagcacttgcaaaacttcatgaagtttttcctgaaatgcaaatcctagccgttagc
ggtaactactgtacagacaaaaaacctgctgctataaattggatagagggaagaggaaaa
tctgttgtttgtgaagctgtcattccagcaaaggttgtcagagaagtattaaaaaccact
acagaagctttggttgaagttaacataagcaagaatttggtgggctcagccatggctggt
agcataggaggctataatgcacatgcagccaatattgtaactgccatcttcattgcttgt
gggcaggatgcagctcagaatgtgtgcagctctaattgtatcactcttatggaagcaact
ggccccttaaatgaagacctgtatatcagctgtactatgccatccatagaaataggaact
gttggtggaggaaccaacctgctaccacagcaggcctgtctgcagatgctaggtgttcaa
ggagcatgcaaagacaaccctggtgaaaatgcccgtcagctcgcaaaaatcgtgtgtggt
acagttatggccggggagttatcactgatggctgcgttggctgcaggacacctagtcaaa
agccacatgatccacaacaggtcaaaagtaaacctacaaaatctccaaggaacctgcacc
aagaaagtggcttga
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