Trichosurus vulpecula (common brushtail): 118858957
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Entry
118858957 CDS
T10126
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp00310
Lysine degradation
tvp01100
Metabolic pathways
tvp05202
Transcriptional misregulation in cancer
Brite
Enzymes [BR:
tvp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
118858957 (DOT1L)
Chromosome and associated proteins [BR:
tvp03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
118858957 (DOT1L)
HMT complexes
Dot1-containing complex
118858957 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
118858957
NCBI-ProteinID:
XP_036625370
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Position
1:58671813..58783169
Genome browser
AA seq
1514 aa
AA seq
DB search
MRLCLEDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRA
IDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSF
DLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDRE
FRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMK
EGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTI
LENYFSSLKNPKLREEQEAARRRQQRESKSNTTTPTKVQENKGTVALEPRADSGAEEDKN
GTAALKKPSPSKPRKKKLNKKGRKMAGRKRGRPKKMSAANPERKPKKTPTALELLHAQTV
SQAAASSPQDAYKSPHSPYYQLPPKVQRHSSNQLLATPTPPALQKLLESFKVQYLQFLAY
MKTPQYKANLQQLVEQEKEKNTQLLGTAQQLFSHCQAQKEEIKRLFQQKLDELGVKALTY
NDLIQAQKEISAHNQQLKEQTKQLESDNSELRNQSLQLLKARCEELKLDWSTLSLENLLK
EKQALKNQISEKQKHCLELQISIVELEKSQRQQELLQLKSYAPADEALSVHLRSKSSFSR
ELETDPARFQLELECSKLSLPHINSMSPELSMNGHAASYEIHSMLSRPSSKQNTPQYLTS
HLDQEIVPCTPIHNNRQKADKLSSLSLPDYTRYSPAKLALRRHLNQDHVVHGKATTNEIH
HRAEHAKENGLTYQSPGMSNGLKLSPQETRPSSPSALQIAGEKSSDKVLKERAYASNGET
ITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAEKVRNTPSPVHQNRDSTSATLEKQFGA
NSHNGMNSAVGNKSLALATSGFSYSGSLAVNGTLSSSPAHLNHGAEQAALDDSSNSGSLF
NSVGSRSSTPQHPSLLMMQSRNSGQNSPAHPLAASPRLNGASQSMMGILQYSDTPKLFSE
GNLKQSPSNKHSPLTASIRTDCGQACVQEGKKRGRRKRSSTGNPGVNSAVSPKRKPLPSV
AGLFTQSSGSPLNINSMVNNINQPLEITAISSPENSLKNSPIPYQDNDQPPVLKKEKPLI
QTNGAHYSPLTSDEEQGSEDEHNSTRIERKIATISLESKSPQKTENGGGLTGRKQTQLTE
GINSSKWKSTFSPISDINLTKTSDSPLQAASSLSQNSLFAFRPSSEDTVAIDAKISVHTR
KNFPSSLSGTDGLSPNTNSSNGFSYAGGLSAADMSLHSFHDGASLSHKTTEVASLSSPLG
FQAQRSKDSSDANPFLNKRQLDGLGSMKGEELQRAGGRSKEVLDMGLQLGGPSDKGSLQH
NGKAGKGRDRDLEFKNGHNLFISAAAAAVPPGGLLNGKGLSSTASAAGHPASSVSTHHPF
LNTFTTGSQFPLGPMSLQANLSSVAGSSVLQSLFNSMPAAASLVHVSSAATRLTNSHAMG
NFSSGVTGGTVGGN
NT seq
4545 nt
NT seq
+upstream
nt +downstream
nt
atgcgtttgtgtctggaggacaaacaccatgatgctgctcatgaaatcattgagaccatt
cgatgggtctgcgaagaaataccggatctcaagcttgccatggaaaattatgttttaatt
gactatgatactaaaagctttgaaagtatgcagagactctgtgacaagtataaccgagcc
attgatagcattcaccagctgtggaaaggaaccacccagcctatgaaattgaacactcgg
ccatccaatgggcttcttcgacatatcttgcagcaagtatataaccactcagtcacagat
cccgagaaactcaacaactatgagcccttttctccagaggtgtatggagaaacttcattc
gacttagttgcccaaatgattgatgagattaaaatgacagaggatgatttgtttgttgat
ttgggcagtggagtgggacaggtggttttgcaagtagctgcagccacaaactgcaaacat
cactacggtgtggagaaggcagacatcccggcgaagtatgcggagacaatggacagagaa
ttcagaaaatggatgaaatggtatgggaagaagcatgcagaatacacactggaaagaggt
gacttcctttcagaagaatggcgggaaagaattgcaaacacaagtgttatttttgtgaat
aattttgcctttggtcctgaggtggatcaccaactgaaggagcgatttgctaacatgaag
gaaggtggcagaatcgtgtcctccaaaccttttgcacctctaaactttagaataaacagt
agaaacttgagtgatattggcactataatgagagttgtggaactatcaccactgaaaggg
tcggtttcatggactggcaagccagtttcttactacctgcatactattgatcgaaccata
cttgaaaactatttttctagtctcaaaaatccaaaactcagggaggagcaggaggcagct
cgccgccggcagcaaagagaaagcaagagcaacacgacgactccgacgaaggtccaagaa
aacaagggaactgtcgcattggagcctcgagcggattctggtgctgaagaagataaaaat
gggacggctgctcttaaaaagccatctccttccaagcctcgcaaaaagaagttaaacaaa
aaaggaaggaagatggcaggaagaaaacgtggacgtcccaagaaaatgagtgctgcaaac
cctgaacggaaacccaagaagactccaactgcactggagcttctacatgctcagactgtg
tcccaggcagctgcatcctctcctcaggatgcatacaagtcacctcatagtccatattat
caactacctcctaaagtacaacggcattcctccaaccagctattggcaacaccaacccca
cctgcactccagaagctattagaatcatttaaggttcagtacctgcagttcctggcctac
atgaaaacccctcagtacaaggcaaacctgcagcagttggtggagcaggagaaggaaaag
aacactcagttgttaggcacagcccagcagttgttcagccactgtcaggctcagaaagag
gagatcaagagattgtttcaacagaaacttgatgagttgggagttaaggctctgacctac
aatgatctgatacaagctcagaaagagatctctgctcacaaccaacaactaaaagaacag
acaaagcagctagaaagtgataacagtgaactcaggaaccaaagcttgcagctgcttaag
gctcggtgtgaagaactgaagctggattggtctactctctcactggaaaatttgctgaag
gagaagcaggcactgaagaatcaaatttcagagaagcaaaagcactgtctggaacttcag
atcagcattgtggagcttgagaaaagccaaaggcagcaagagctactgcagctgaaatcc
tacgcaccggctgatgaggccctgtccgtccacctgcgaagtaaaagcagcttcagccgc
gagctggagactgaccctgccaggttccagctggagctcgaatgctccaagttgtccttg
ccccacatcaatagcatgagccccgaactctctatgaatggccatgcagcctcctatgag
attcatagtatgcttagccgaccttcttccaaacaaaacactccacagtatctgacctcc
cacctggaccaagaaatagttccttgcacccccattcataacaacagacagaaggcagac
aaactgtcaagcttgtccttacctgattacaccaggtattcccctgctaagttagcccta
aggagacacttgaatcaggatcatgtagtccatggaaaagctacaactaatgaaatacac
cacagagctgaacatgcaaaagagaatggcctgacatatcagagtcctggtatgtcaaat
ggcctaaagctgagccctcaggaaactcggccttcctccccctcggccttacagattgca
ggagagaagagcagtgacaaggttttaaaagagagagcctatgccagcaatggagaaaca
atcaccagcctccctatcagtattcctctcagcacagtgcagcccaacaaacttcctgtc
agtatcccattggccagtgtagtgttgcctagccgtgcggagaaagtgaggaacacgcct
agtccagttcatcagaatcgagactctacttcagcaacacttgagaaacagtttggtgct
aattcccataatggtatgaacagtgctgtaggaaacaagtcccttgctttggctacctca
ggtttttcttatagtggctccttggcagtcaatggcacgctttccagtagcccagcccat
cttaaccatggtgctgagcaggcagccctagacgattcttccaattcagggagcctcttt
aattcagtgggttcccggagctctacaccacagcatccttctttactcatgatgcagtcc
cgcaactctggccagaactctccggcccacccgcttgctgccagccctcgcctcaatgga
gcttctcaaagcatgatggggattttgcagtactcggatactccaaaattgttctctgaa
gggaacctgaagcagtctccttccaacaaacacagtcctctgacagctagcattcgcaca
gactgtggacaggcttgtgtgcaggagggcaagaagaggggcagaaggaagcggtcttcc
acagggaatcctggtgtgaattctgcggtatctcccaagcgcaagcccttaccgtctgtg
gcaggcctcttcacccagtcttcaggctcacccctcaatattaactctatggtcaataac
attaatcagcctttagaaataacagccatttcctcccctgaaaactccctgaagaactct
cctattccttaccaggacaacgaccagcctcctgtgctgaaaaaggagaagcccttgatc
cagacgaatggggcgcattactcgcccctgacctccgatgaagagcaaggatctgaagat
gagcacaacagcaccaggattgaaaggaaaattgcaacaatctctttagagagcaagtct
ccccagaaaacagaaaatggtggtggccttacaggaaggaagcaaacccaactgaccgaa
ggcatcaacagtagtaaatggaagtctaccttttcaccaatatcagacatcaaccttacc
aaaacatctgacagccccttacaggcagcttcgtccctgagccagaattccctgtttgcc
ttccggccatcctcagaggatacagtggctattgatgccaagatctctgtgcacacaagg
aaaaacttccctagttcattgtcagggacggatggtctcagtcccaacacaaactcctcc
aatggattctcatatgctgggggcctgtcagctgctgacatgagtttacacagctttcac
gatggtgcttctctttctcacaaaaccactgaggtggccagcttaagctcccctctgggt
tttcaggcacagcggagcaaagacagctcagacgccaacccttttctgaacaagaggcag
ctggatggcctgggaagtatgaaaggggaagagctacagagggccggaggcagaagcaaa
gaggtgctcgacatgggcctgcagctggggggcccttctgacaagggttccttgcagcac
aatggcaaggctggcaaaggacgggaccgagatttggagtttaaaaatggccacaatctt
ttcatttctgctgctgccgccgccgtacctccaggaggcctcctcaatggcaagggcctt
tccagcacggcctctgcggctggccaccctgcttcttctgtttcgacgcaccaccctttc
ctaaacactttcaccactggatcccagtttcccctgggccctatgtccctgcaggccaac
ctcagctcggtggcaggctcttcagtattgcagtctttgtttaattccatgcccgctgct
gccagtttggtccacgtgtcgtcagctgcgaccagattgacaaattctcacgcaatggga
aacttctcttctggggttacaggtggaacagttggaggtaactag
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integrated database retrieval system
