Thermoactinomyces vulgaris: AB849_010925
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Entry
AB849_010925 CDS
T05864
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tvu
Thermoactinomyces vulgaris
Pathway
tvu00300
Lysine biosynthesis
tvu00550
Peptidoglycan biosynthesis
tvu01100
Metabolic pathways
tvu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tvu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AB849_010925
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AB849_010925
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AB849_010925
Enzymes [BR:
tvu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AB849_010925
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
LpxD
Motif
Other DBs
NCBI-ProteinID:
QBK14062
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Position
complement(2150888..2152273)
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AA seq
461 aa
AA seq
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MKAIQLNKLAQIMGGRLTAGSPSKIVQSLNFGNPKQLKPHQVYFYTRKIRWHEKQLPAIQ
RIRPLAVVLPAHLFARGIPPGTSIIRVKDAYQAFFKAGLWNWKQCPARVIGITGSAGKTT
TTEMVASILKYRAPMVKTHRNLNTFSFLPTYLTRLTGKEKLLLLEMGMKSLNNIRKQCQI
VRPEIGAVTNVGEAHAGSLGGLHLIVKAKQEMVDGVRKNGTLILNADDPRSRKLKTNRFQ
GKILTFGIRNPAHIRGKNIRYTRNGMVFDAVLQGRQFPVRIPVFGTHNVYNALTAIGVAW
AYGATIPEIQKGLATFKAPKMRLEFIRTKSGRILINDAWNANPTALKAGLDVLKNVSGSR
PKIAVLGDMLELGEYSHQAHMQSGKYAARLGLTQLITLGKRGAIIAQSAIANGMSRKRVL
ICKDFRQALHHLAKTPKNAVIYFKASRSLHFEKLVKQLKRL
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaaagcaatccaattaaacaaactggcccaaatcatgggcggaagattgactgcaggt
tccccgtccaaaatcgtccagtccctcaatttcggaaatccaaaacaattgaaaccgcac
caagtctacttttacacccgcaaaattcggtggcacgaaaagcaactgccggccattcaa
cggatccgcccgctcgccgtcgtgctccccgctcacctttttgcccggggaatcccgccg
ggcacttcgatcatccgggtgaaagatgcttatcaggctttttttaaagccggtctttgg
aactggaaacaatgcccggccagagtgatcggcatcacgggaagtgcgggcaaaacgacc
acgaccgaaatggtggcttccattttgaaatatcgtgcaccgatggtgaaaacccatcgc
aacctgaacactttttcttttttgccaacatatctgacccggttaaccggcaaagaaaaa
ttgctcctcttggaaatgggaatgaaatcgctcaataacatccgcaaacaatgccaaatc
gtccggcccgagatcggtgccgtcaccaatgtcggagaagcgcatgcgggcagcttgggc
ggacttcatctcatcgtaaaagccaaacaggaaatggtggatggtgtccgcaaaaacgga
accttgatcttaaatgcggacgacccgcggtcaagaaaactgaaaaccaaccgattccag
ggaaaaatccttaccttcggcatccgcaatccggcccacatccgggggaaaaacatccgt
tacacccgaaacgggatggtctttgacgccgtgcttcagggacgccagttccccgtccgg
atccctgtcttcggcacacacaatgtttataacgccctgaccgccatcggggttgcctgg
gcttatggagccacgattccggaaattcaaaaagggctcgccacctttaaagcgccgaaa
atgcgcttggaattcattcgcacaaaatccgggcgcatcctgatcaatgatgcttggaac
gccaatcccacagcactgaaagccggattggacgtcctgaaaaatgtcagcggatcccgc
cccaagattgccgtattaggcgacatgctggagctcggggaatattcgcatcaagctcac
atgcaatcagggaaatatgcggcgcgcttggggttgacgcaactcatcaccttgggcaaa
cgcggggcaatcattgcccaatctgccatcgccaatggaatgagccgcaaaagggtactg
atttgtaaagatttccggcaagcattgcaccacttggcaaaaaccccgaaaaatgcagtc
atctattttaaagcctcccgttccctccatttcgaaaagctcgtcaagcaattaaaaagg
ctgtaa
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