Thermoanaerobacter wiegelii: Thewi_0016
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Entry
Thewi_0016 CDS
T01607
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
twi
Thermoanaerobacter wiegelii
Pathway
twi00290
Valine, leucine and isoleucine biosynthesis
twi00660
C5-Branched dibasic acid metabolism
twi01100
Metabolic pathways
twi01110
Biosynthesis of secondary metabolites
twi01210
2-Oxocarboxylic acid metabolism
twi01230
Biosynthesis of amino acids
Module
twi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
twi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Thewi_0016
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thewi_0016
Enzymes [BR:
twi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Thewi_0016
4.2.1.35 (R)-2-methylmalate dehydratase
Thewi_0016
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Motif
Pfam:
Aconitase
AcnX
Cauli_VI
Motif
Other DBs
NCBI-ProteinID:
AEM77532
UniProt:
G2MSH1
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Position
18232..19488
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AA seq
418 aa
AA seq
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MGLTLTQKILSAKVGREVKPGELIEVDVDMVLGNDVTAPVAIKEFEKIGKEEVFDKTKIA
LVPDHFVPNKDIKSAEQVNIMRKFAKKHGIVNFFEVGQMGIEHALLPEKGLVLPGDVVIG
ADSHTCTYGALTCFSTGVGSTDMAAAMATGKAWFKVPEAIKFVLKGNLQKWVSGKDVILY
IIGKIGVDGALYKSMEFTGNIKALSMDDRFTIANMAIEAGAKNGIFDFDEITEAYVKGRA
KREYKVFERDEDAEYSEVYEINLDEIRPQVAFPHLPENTRNIDEIGKVKIDQVVIGSCTN
GRMSDMEIAYKILKGKKVHPDVRLLIFPATQEIYLECVKRGYIEEFIKAGAAVSTPTCGP
CLGGHMGILAKGERALATTNRNFVGRMGHPESEVYLSSPAVAAASAIAGYIVSPEEVE
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
ttgggcttaacattgacacaaaagatattgtcagcaaaagtcggtagagaagtaaaacca
ggagagttaatagaagtagatgtggatatggtgttaggcaatgacgttactgctcctgtt
gctataaaggagtttgaaaagataggaaaagaagaggtatttgacaaaactaaaattgcc
cttgtacccgaccattttgttcctaataaggacataaaatcggcggagcaagtaaatata
atgagaaaatttgcaaaaaaacatggaatagtaaacttctttgaagtagggcaaatggga
atagagcacgcacttttacccgaaaaaggacttgtacttccgggggatgttgtcataggt
gctgattctcatacttgcacttatggcgctcttacctgtttttctacaggagtaggaagc
actgacatggcggcagcaatggcgacaggcaaagcgtggtttaaagtgccagaagcaata
aaatttgtgttaaaaggcaatttgcaaaaatgggtaagtggaaaagatgttatcttgtat
ataatcgggaaaataggggttgacggagctttatataaatctatggaatttacagggaat
ataaaagctttgtcaatggacgatagattcacaattgccaatatggcaatagaagcaggg
gctaaaaacggtattttcgattttgacgaaattaccgaagcatatgttaaagggagagca
aaaagagagtataaggtatttgaaagggatgaagatgctgagtacagtgaggtttatgag
ataaatttggatgagataaggcctcaagtagcatttcctcatttgcctgaaaacactaga
aatattgatgaaattggaaaagttaaaatagaccaagtagttattggctcttgcaccaat
ggacgcatgtcagacatggagatagcttataagatattgaaaggcaaaaaggtccatcct
gatgtaagacttttaattttccccgcaacacaggaaatataccttgaatgtgttaaaaga
ggttacatcgaagagtttataaaagcaggtgcggcagtatctactcctacttgtggacct
tgccttggcggacatatgggaattctggctaaaggagaaagggcactggctactactaac
agaaattttgtaggaagaatgggacatcctgagagtgaagtgtatctttcaagtccagct
gttgcagccgcttcagctattgcaggatatatcgtaagtccagaggaggtagaatga
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