Thermoanaerobacter wiegelii: Thewi_0673
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Entry
Thewi_0673 CDS
T01607
Name
(GenBank) Phosphoribosylformylglycinamidine synthase 2
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
twi
Thermoanaerobacter wiegelii
Pathway
twi00230
Purine metabolism
twi01100
Metabolic pathways
twi01110
Biosynthesis of secondary metabolites
Module
twi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
twi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Thewi_0673
Enzymes [BR:
twi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Thewi_0673
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Paralog
GFIT
Motif
Pfam:
AIRS
AIRS_C
FGAR-AT_linker
PBP5_C
Motif
Other DBs
NCBI-ProteinID:
AEM78126
UniProt:
G2MSR1
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Position
695455..697656
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AA seq
733 aa
AA seq
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MDKIWRELGLTDEEYEKIISILGREPNITELGMYSVMWSEHCAYKNSKPLLKYLPTKGER
VIQGPGENAGVLDIGDNLAVVMKIESHNHPSAIEPYQGAATGVGGIIRDIFTMGARPIAL
LDSLRFGIPDDKRTKYLIENVVAGIADYGNCIGIPTVGGDTYFEESYKGNPLVNAMCVGI
VEKDKIKKGIAKGVGNPVMIVGATTGRDGIGGASFASQELSEESEEKRPSVQVGDPFMEK
LLLEACLELYETDAVVAIQDMGAAGLTSSSCEMASRGGTGMELDLDKVPLREEGMTPYEI
MLSESQERMLVVVEKGKEEDVQKVFKKWGLNAATIGKITDDGMIRVIKDGKVVAEVPAKS
LTEDAPQYVREEEVPKWQEDVNKLDINEIKPPEDMNKALKDVISSLNIASKEWIYSQYDY
MVRTDTVITPGMDAAVVRIKGTKKAVALTTDCNGRYCYLDPYIGSQIAVAEAARNLCMVG
AKPIGVTDCLNFGNPEKKEIYWQLKNSIFGIAKACETLQIPVVSGNVSLYNENEGEAIYP
TPVIGMAGLIEDVSKICTMDFKKERDVIIILGENKGEIGGSEYLKVCFGMVKGQPPQIDL
EEEKRLQELVLKLIDKSLINSSHDISEGGFAAALVESAISGKKGAKISLQTSLREDIELF
SESQPRALIAVSPEKVEEVLKIAYEHQVPAQKVGVVEGKDIVIDVNGKRIIDLPLEVLEE
SWRGRIKWEMERN
NT seq
2202 nt
NT seq
+upstream
nt +downstream
nt
atggataaaatatggagagaattaggacttactgatgaggagtatgagaagattatttcg
atattaggaagagagcctaatataactgaattaggtatgtatagtgttatgtggtctgaa
cattgtgcctataaaaattctaaacctcttttaaaatatttacctacaaaaggcgaaaga
gtaatacaaggaccgggagaaaatgcaggagtattggatattggagataatttggcagtt
gtgatgaagatagaaagccataaccacccttctgcaattgaaccctatcaaggagcagct
acaggtgttgggggaataataagagatatattcacaatgggggcaaggccaattgctctt
ttagattctttaagatttggaattcctgatgataaaaggactaaatatctcatcgaaaac
gtggtagcaggtatagcggattatggaaattgcataggaattcctacagtgggtggggat
acctattttgaagaaagttacaaaggaaatcctttagtaaatgcgatgtgtgtaggaata
gtagaaaaagacaagataaaaaaagggatagcaaaaggtgtaggtaaccctgttatgata
gtaggtgctactacggggagagacggtattggaggtgcaagttttgcttctcaggaatta
agcgaggaatcagaagaaaaaagaccttctgttcaagttggcgacccctttatggaaaaa
ctgcttttggaggcttgtttagaactttatgaaacagatgccgtagttgctatacaagat
atgggtgcggcaggtcttacctcttcttcttgcgagatggcttcccgcggtggaactgga
atggagcttgaccttgataaagtgcctttgagagaagagggaatgacaccttatgaaata
atgctttctgaatctcaagagaggatgttggttgtagtagagaaaggcaaggaagaagat
gtacaaaaggtatttaaaaaatggggactgaatgccgccacaatagggaaaattactgat
gatggaatgataagagtgattaaagatggaaaagtagttgcggaagttccagccaagtct
ttgacagaagatgctccacaatatgtgagagaagaagaagtacctaaatggcaagaagat
gtcaataagttggatataaatgaaataaaacctccagaggatatgaataaagctctaaaa
gatgtaatttcttctttaaatattgcaagtaaagaatggatatacagtcaatatgattat
atggtgaggacagacacagtaataactccgggaatggatgcggctgttgtgaggataaaa
ggtacaaaaaaagctgttgcattgacaactgattgcaatggtagatattgttatttagat
ccctatataggctctcaaattgctgtagcagaggcagctcgaaatctttgtatggttggt
gctaagcctataggggttacggattgtttgaattttggcaatccggaaaagaaagaaata
tattggcagttaaaaaattctatatttggaatagctaaagcctgtgaaacacttcaaatc
cctgtggtaagcggaaatgtcagtctttacaatgaaaatgagggagaggccatttatcct
actcctgtaataggaatggcaggtcttatagaggatgtatcaaaaatttgtacaatggac
tttaaaaaagaaagagatgtaattataattttaggtgagaataaaggagagattggagga
agtgagtatcttaaagtttgctttggaatggtaaaagggcaaccacctcaaatagactta
gaagaggaaaaaagattgcaagaattggtgttaaaacttattgataaaagcttaattaat
tcttctcatgacatatcagagggcggttttgcggctgctttggttgaaagtgcaatttca
ggcaaaaaaggtgcaaaaatttcgctacaaacttctctgagagaggatatagagttgttc
tctgaatctcaaccaagagcattaattgctgtaagtcctgaaaaagtagaggaagtatta
aaaatagcttatgaacaccaagttccagcgcaaaaagtaggagttgtagagggtaaagat
attgtaattgatgtaaatggtaaaagaataatagaccttcctttagaagtcttagaggaa
agctggagagggagaataaaatgggaaatggagagaaattaa
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