Thermoanaerobacter wiegelii: Thewi_0889
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Entry
Thewi_0889 CDS
T01607
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
twi
Thermoanaerobacter wiegelii
Pathway
twi00790
Folate biosynthesis
twi01100
Metabolic pathways
twi01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
twi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Thewi_0889
Enzymes [BR:
twi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Thewi_0889
6.3.2.17 tetrahydrofolate synthase
Thewi_0889
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
DUF2368
YvbH_ext
DUF5795
Motif
Other DBs
NCBI-ProteinID:
AEM78319
UniProt:
G2MWE9
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Position
925891..927174
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AA seq
427 aa
AA seq
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MNYEEAISYIHGTYKFGIKLGLENIRRLLNYMGNPQKNLKIIHVAGTNGKGSTSAFISNI
LQQAGYKVALYTSPYLEEFEERMRINGENISKEKLIYYVEYIKPIISRMVEEGYNHPTEF
EVVTAIAFKYFYDEKVDFVVLEVGLGGRFDATNAIDFSLVSVITTIDYDHTDRLGHTLGE
IAYEKAGIIKRNGVVVSFYQQPEALKVIIEACEVRNAYLTVLEKSNVIIKEQNPDFQIFD
YKKYKDLKITLLGEHQIYNAALAIESVEKLKMYGYEITEKDIREGLYRAKWPGRLEVMRK
KPYVVIDGAHNPQGMTVLKESLKLFKYDKLILVIGMLKDKDTQKMLDIIVPEANMIITTT
PISERAYKASELAERIEKEKVIAIENIEEAVKYALDIAKEEDMVLFCGSLYMIGYVRSML
KKVIIKT
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgaactatgaagaagcaattagctacatacatggtacatacaaatttggcataaagttg
ggattagaaaatataagaagattattaaattatatggggaatcctcaaaaaaaccttaaa
attatccacgttgctggtacaaatggaaaaggctctacatcagcttttataagcaacatt
ttgcagcaggctggatacaaagtagctttatatacttctccctacctcgaagaatttgaa
gagagaatgagaataaatggagaaaatatttccaaggaaaagttgatttattatgttgaa
tatataaagcctataatatctcgtatggtggaggaaggatacaatcatccgacggaattt
gaagtggtaactgcaattgcttttaaatatttttatgatgaaaaagtggattttgtagtt
ttagaggtaggacttggaggtagatttgacgcaacaaatgctattgatttttcattagtt
tctgttataaccactattgattatgaccatacagacagattgggacatactttaggagag
attgcatatgaaaaggcaggcattatcaagcgaaatggagtggtggtaagtttttatcaa
cagccagaagcattgaaagtcatcatagaagcatgtgaggtaagaaatgcttatttgact
gtacttgaaaaaagtaacgtaattataaaagaacaaaaccctgattttcagatttttgac
tacaaaaaatacaaggacttaaaaattactttattgggagaacatcagatttacaatgct
gctttggcgattgagagcgtagaaaaattaaaaatgtatggatacgaaatcacagaaaaa
gatataagggaagggctttacagggcaaaatggcctggaagattggaagtaatgagaaaa
aaaccctacgtagtaatagacggtgctcacaatcctcaaggaatgactgttttgaaagag
tctctaaaattatttaaatatgataaattgattttagtaattggaatgcttaaagacaaa
gatacacagaagatgttggatataattgtgccagaggcaaatatgataataacaaccacc
ccaataagtgaaagagcttataaggcaagtgaacttgcagagcggatagaaaaagaaaaa
gtgattgcgattgaaaatattgaagaagcggtaaaatacgccctggatatagctaaggaa
gaggatatggtacttttttgtggttcattgtacatgattggttatgtgaggtctatgctt
aaaaaggtaataattaagacatag
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