Thermoanaerobacter wiegelii: Thewi_1774
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Entry
Thewi_1774 CDS
T01607
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
twi
Thermoanaerobacter wiegelii
Pathway
twi00290
Valine, leucine and isoleucine biosynthesis
twi00620
Pyruvate metabolism
twi01100
Metabolic pathways
twi01110
Biosynthesis of secondary metabolites
twi01210
2-Oxocarboxylic acid metabolism
twi01230
Biosynthesis of amino acids
Module
twi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
twi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Thewi_1774
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thewi_1774
Enzymes [BR:
twi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Thewi_1774
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
ComA
AAA_lid_5
Motif
Other DBs
NCBI-ProteinID:
AEM79167
UniProt:
G2MWQ5
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All DBs
Position
complement(1776998..1778560)
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AA seq
520 aa
AA seq
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MKNLRIYDTTLRDGVQGQGISFTVEDKLKIVKALDEFGVAYIEAGNPGSNPKDIEFFEKV
KNIKLKNAKLIAFGSTRRANTTTEEDANVISLLNAGTEVVTIFGKSWDFQVIEILKTTLE
ENLKMIYDTVKFFKDKGKSVIFDAEHFFDGYKQNPEYALKTLEVALEAGADSVCLCDTKG
GAFPMEVYEITKTVVDKFNTEVGIHCHNDNGMAVADSIMAVQAGAIQVQGTINGYGERCG
NANLCTLIPNLQLLMGYKCVPDENLKQLTHLARFVSEIANVTYDERAPYVGKNAFSHKAG
MHADAVNKNTYSYELIDPSLVGNSRTFLISEVAGRGTVLNAINEIDPTITKNSPETKLIL
DKLKEMEYLGYQYENAGGSLELLIRKVLGKYKPAFNLKEFKVIVNEPSVNSVNSSALIKV
EVDSIEEIAAAEGDGPVHALDNAVRRVLERFYPQIKEMRLTDYKVRVLDSNSATAAKVRV
IIESTDGKDSWSTIGVSTDIIEASWRALVDSIEYKLNKES
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
gtgaagaacctacgcatatacgatacaacattaagagacggagttcaaggacaaggtata
tcttttactgtggaagataaattaaaaatagttaaagcgcttgatgagtttggtgtggcc
tatattgaggcaggtaatcctgggtctaatcctaaagatattgaattttttgaaaaagtt
aagaatattaaattaaaaaatgctaaattaattgcttttggtagcacaagaagagcaaat
acaactaccgaagaagatgctaatgtaatttcactcttaaatgctggcacagaggtagta
actatctttggcaagtcatgggattttcaagttatagaaattttgaaaactactttagaa
gaaaacttaaaaatgatttatgatacagtaaagttttttaaagacaaaggtaagtcagtt
atatttgatgcagagcatttttttgatggttacaaacaaaatccagagtatgctttaaag
acattagaagtagcattagaggcgggagcagacagtgtatgcttgtgcgatacaaaaggc
ggagcttttcctatggaggtttatgaaataacaaaaactgttgtggataaatttaataca
gaagtaggaatacactgtcataatgataacggaatggctgtcgcagattctataatggca
gtacaagcaggggcaatacaagtacaaggtacaataaacggttatggtgaaagatgtggc
aatgcgaatttatgtaccttgataccgaatttgcaattacttatgggatataaatgtgtg
cctgatgaaaatctaaaacaattgactcatttagccagatttgtaagtgaaattgcaaat
gtcacttacgatgaaagggcgccttatgttgggaaaaatgctttttcccacaaagcgggg
atgcatgctgatgctgtaaataaaaatacttattcttatgaactgattgacccttcttta
gtgggaaatagtaggacctttttgatttctgaagttgcaggcagaggaacagtgctaaat
gccataaatgaaatagatccaactattacaaagaattctcctgaaacaaagttaatttta
gataaattaaaagaaatggagtatttagggtatcaatatgaaaatgcaggaggttcttta
gaacttttgataagaaaggttcttggaaaatataaaccagcatttaatttaaaagagttt
aaagttattgtaaatgagccttctgtaaatagtgttaattcttcagcacttataaaagtg
gaagtcgatagtatagaggagatagctgcagctgagggagatgggccagtacatgctctt
gataatgctgtaagaagagtactggagagattttacccacagataaaagaaatgaggttg
acagattataaagtgagggttttggattctaattctgcaactgctgctaaagttagagtt
ataatagagtcgacagacggaaaagattcatggagcacaattggggtttctacagatatt
attgaggccagttggagagcccttgttgattcaatagagtacaaacttaacaaagaaagt
taa
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