Tropheryma whipplei TW08/27: TW547
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Entry
TW547 CDS
T00117
Symbol
murF
Name
(GenBank) probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tws
Tropheryma whipplei TW08/27
Pathway
tws00300
Lysine biosynthesis
tws00550
Peptidoglycan biosynthesis
tws01100
Metabolic pathways
tws01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tws00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TW547 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TW547 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TW547 (murF)
Enzymes [BR:
tws01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TW547 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
IMP_cyclohyd
Hid1
Motif
Other DBs
NCBI-ProteinID:
CAD67213
LinkDB
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Position
complement(583384..584778)
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AA seq
464 aa
AA seq
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MLIRRADIQRVTGGILHNTSLSESLLPINGRLKIDSRNISQGDIFVAHTGTKFDGHEFLY
QAKQSGASLAIVTRVQEIDLPQLLVGNVTEAMHAIAGFKLCLSRDTITVIGITGSNGKTT
TKSVLAYVLSKFGNTVATHGNQNNEIGFPITVSRIEPLTKYLVLEYGAFKPGDIDCLKKI
AVPDIAVLLSAGHAHVEKSGSLESVCSMKAELARDLPEGSKVLLNYDDPRIARLSVGNRY
YFGTDKRAHFRASHVETNIIKTRFIVTYQKGSVEVETKLIGKHQVSNVLAALSTLVLLGF
DAEVCARYISEVNPIDGRMQYIPLGDFSIIHDAYNASFESVKCALDSLVVLGSLAKRRIA
VLGRIHDMGELAQDVYRQLVKQFLDTDINLLVIVSEKQMYLIAKELAKGVPNKEIVWFED
LETAKHEIFDLFSPGDIVLFKASNAENFSSLVESVKHKAGKFAG
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgctaatcaggcgtgccgatattcaacgcgtgaccggcggtattttgcacaacacctct
ttatcggaaagtttgttgccaattaacgggcgcctgaagatagattcaaggaatatttca
cagggcgatatttttgttgctcacactggcacaaaattcgacgggcatgagtttttatat
caggcaaagcagtctggtgcaagccttgcaattgtgacgcgtgtacaggaaattgacctt
ccacagttacttgttggcaatgtcacagaagccatgcatgcaattgcaggttttaaacta
tgtctcagcagagatacgattacggtgattgggatcacggggtcgaatggtaagacaaca
accaagagtgttctcgcatatgttctgtcaaaatttggtaatactgtggcaactcatggt
aatcagaataatgaaataggttttccaatcactgtttccagaattgagcctttaacaaaa
tatcttgtccttgaatacggtgcatttaagcctggtgatatagattgtttaaagaagatc
gctgtgcccgatattgcagttctcttatcagcaggccatgctcatgttgagaaaagtggc
agtttagaaagtgtctgttcaatgaaagctgagcttgcgcgcgacctgccagagggatca
aaggtattgctcaattatgatgacccgaggattgccaggctctctgttggaaatcgatat
tattttggaacggataagcgcgcgcattttcgggcgagtcacgtagaaacaaatataatc
aagacgcgtttcattgttacttatcaaaagggtagcgtggaggttgagactaaactgata
ggtaaacaccaggtcagtaatgttctggctgccctgtcgactcttgtgcttttgggattt
gacgctgaggtgtgcgcacggtatatatcagaggttaacccgattgatgggcgtatgcaa
tatattcctctcggagacttttccattattcatgatgcctacaatgcgtcctttgaatcg
gtgaagtgcgctcttgactcgcttgttgttttggggtctctagccaaacggcgtattgct
gttcttgggcgaatacatgatatgggggagctggcacaagatgtgtataggcagcttgtc
aaacagtttttggacacagacattaatcttctggttattgtttcagagaaacagatgtat
ctcatagctaaggaattggccaaaggagtgccaaataaggagattgtgtggtttgaagat
ctggaaacagcaaaacatgagatatttgatttattttctccaggagatatagttcttttc
aaagcctcaaatgcggagaatttttctagcctcgtggagagtgtaaagcacaaagcaggc
aagtttgcgggatga
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