KEGG   Tropheryma whipplei TW08/27: TW565
Entry
TW565             CDS       T00117                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
tws  Tropheryma whipplei TW08/27
Pathway
tws00290  Valine, leucine and isoleucine biosynthesis
tws00770  Pantothenate and CoA biosynthesis
tws01100  Metabolic pathways
tws01110  Biosynthesis of secondary metabolites
tws01210  2-Oxocarboxylic acid metabolism
tws01230  Biosynthesis of amino acids
Module
tws_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
tws_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:tws00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TW565 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    TW565 (ilvC)
Enzymes [BR:tws01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     TW565 (ilvC)
SSDB
Motif
Pfam: KARI_N KARI_C F420_oxidored NAD_binding_2 2-Hacid_dh_C Rossmann-like CoA_binding AdoHcyase_NAD
Other DBs
NCBI-ProteinID: CAD67231
UniProt: Q83HI9
LinkDB
Position
complement(603297..604298)
AA seq 333 aa
MSEIGTRVYTECDADLSLIQNVLVAVIGYGSQGHAQALNLRDSGVNVVIGLKENSASRKS
AQDSGFEVLLPQEAAKKAQLIALLVPDPAQRDVYESAIKHNLSEGDALLFSHGFNIRYGY
ITPPDGVDVLMVAPKGPGHMVRREYLDNRGTPAVFAIEKDASGRCFDLALSYAKGIGALR
AGAIQTTFTEETETDLFGEQAVLCGGLEQLIQYGYETLVEAGYQPEVAYFEVLHELKLII
DLIVEGGLSKSRWSISDTAEYGSYVSGPRVIDKHVKENMKKILGEIRSGEFANRFIKDQD
SGANEFTQLREIAARHPIEEVGARLRALFSWSK
NT seq 1002 nt   +upstreamnt  +downstreamnt
atgagtgaaataggcacgagggtttataccgaatgtgatgcagatttatcgcttattcaa
aatgttctggttgctgttattggttacggatcgcagggtcatgcgcaagcgctgaatctg
cgtgattcgggagtaaatgttgtaattggtttgaaggaaaattcggcttcgcggaaaagc
gcacaagactcggggtttgaggttcttttgccgcaagaggcagccaaaaaggcgcagcta
attgctctgcttgtgccagatccagcacagcgtgatgtttatgaaagtgcaataaaacat
aatctctcagaaggcgatgctcttttgttttcacacggatttaacatccgatacgggtat
ataacacctccagatggtgttgatgttcttatggttgcccctaaaggtcctggacatatg
gttagacgtgaatatcttgataaccgcgggactccggctgtgtttgctattgaaaaggat
gcaagtggtaggtgttttgaccttgcgcttagttatgcaaagggcataggtgctttgcgt
gccggggctatacaaactacatttaccgaagagaccgagacggatttatttggcgagcag
gcagttctatgcggcggtcttgaacagctgatccagtatggctatgagaccttggttgag
gcgggttatcagccagaagttgcttattttgaagttcttcatgaattgaagctaatcatt
gatctgatagttgagggtgggcttagtaaatcacgctggagtatttctgatacggcagaa
tacggcagttatgtatcaggtccgcgtgttatagacaaacatgtcaaggaaaatatgaaa
aaaatacttggtgagattcgttctggcgagtttgctaatagattcataaaggatcaagat
tcaggtgcgaatgaatttacacagctcagagagattgctgcccggcatccaatagaagag
gttggtgccaggctgcgcgcattattttcgtggagtaagtaa

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