Thermoanaerobacterium xylanolyticum: Thexy_0776
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Entry
Thexy_0776 CDS
T01505
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
txy
Thermoanaerobacterium xylanolyticum
Pathway
txy00290
Valine, leucine and isoleucine biosynthesis
txy00620
Pyruvate metabolism
txy01100
Metabolic pathways
txy01110
Biosynthesis of secondary metabolites
txy01210
2-Oxocarboxylic acid metabolism
txy01230
Biosynthesis of amino acids
Module
txy_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
txy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Thexy_0776
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thexy_0776
Enzymes [BR:
txy01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Thexy_0776
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AEF16817
UniProt:
F6BIY5
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All DBs
Position
823068..824627
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AA seq
519 aa
AA seq
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MKNIVIYDSTLRDGAQSQGISFTVSDKIKIVELLDDFGVDYIEAGNPGSNPKDMEFFDII
KRKSLKNSKLIAFGSTRRANTPVEKDANVSSLLLAETEYVAVFGKSWDFHVSEILRTTLD
ENLNMIYDTINYLKKQGKKVVFDAEHFYDGFIENPDYALKTIQVAYDAGADSICLCDTKG
GMFPTEIYDITKKVVDKFDCEIGIHAHNDNGMAVANSIMAVEAGAVQVQGTINGYGERCG
NANLCTILPNLQFKKGIKCVEDDKMRELTVLSRRISEIANAAPDERAPYVGRNAFAHKAG
MHSDAVCKNTRSYEIIDPELVGNERVLLLSEVAGRSALIGIVNEVDPTIDRDSDKTKEIL
DKLKEMESKGYKYEGAEGSLKLLILKTLGLYKPSFRLIEFKVIVNEPSVDDVNSSALIKI
EVDGQEEITAAEGDGPVNALDKAVRKALERFYPEVKEMKLTDYKVRVLDSNSATAAKVRV
IIESSDGNEIWSTIGVSTDIIDASWIALVDSIEYKLNKK
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
gtgaaaaacattgtcatttacgattctacattgagagatggagctcaatcacaggggatt
tcctttacagtatcagacaaaataaagattgttgagcttttagacgattttggtgtagat
tacattgaagctggaaatccaggttccaatcctaaagacatggagttttttgatattata
aaaagaaaaagtttgaaaaattccaagttgatagcatttggcagcaccagaagggcgaac
acacctgtcgagaaagatgctaatgtcagttcgcttctattggcggagacagaatatgtg
gcagtatttggaaagtcatgggacttccatgttagcgagatattgcgaacgactttagat
gaaaatctcaatatgatatatgatacgataaattacttgaaaaagcagggtaaaaaagtc
gtatttgatgcagaacatttttatgatggctttatagaaaatcctgattacgcattgaaa
acaattcaggttgcgtatgatgcaggagcagacagtatctgcctttgtgatacaaaaggt
ggcatgtttcctacagagatatatgacataaccaaaaaggttgtagataaatttgattgt
gagataggcatacatgctcacaatgacaatggtatggctgtcgccaattctataatggct
gtagaagcaggtgcagtacaagtccaaggaacgataaacggatatggtgaaagatgtgga
aatgcaaatctgtgcacgattttgccaaacttgcagtttaaaaaaggaataaaatgcgtt
gaagacgacaagatgagagagcttacggtactttcaagaagaataagtgaaatagccaat
gctgcaccagatgaaagagcaccgtacgtagggagaaacgcatttgcccacaaggcaggt
atgcattcagatgctgtttgcaaaaacacaaggtcgtatgaaatcatcgatccagagctt
gttggcaatgaaagagtgcttctattgtcagaggttgctggcagaagtgctttaataggc
atagtaaatgaagtagatccaaccatagaccgcgattctgataagacgaaagagatatta
gataagctaaaagaaatggaatctaagggatacaagtacgaaggtgctgaaggttcgtta
aagcttttgatattgaagactttgggactgtataaaccttcatttaggcttatagaattt
aaagttatagtcaatgaaccatctgttgatgatgtaaattcatctgccctcataaaaata
gaagtagacgggcaagaagaaataaccgctgcagaaggcgacggacctgtaaacgcactc
gataaggcagtcagaaaggctttagagaggttttatccagaagtcaaggagatgaaactt
acagactacaaagtaagagttttagactctaattctgctacagcagcgaaagtaagggta
ataatagaatcatccgatggaaacgaaatttggagcaccattggtgtttctacagatata
atagatgccagttggatagcgcttgtagactcaatagagtataaacttaataaaaaatga
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