Thermoanaerobacterium xylanolyticum: Thexy_1060
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Entry
Thexy_1060 CDS
T01505
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
txy
Thermoanaerobacterium xylanolyticum
Pathway
txy00300
Lysine biosynthesis
txy00550
Peptidoglycan biosynthesis
txy01100
Metabolic pathways
txy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
txy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Thexy_1060
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Thexy_1060
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Thexy_1060
Enzymes [BR:
txy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Thexy_1060
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2608
Motif
Other DBs
NCBI-ProteinID:
AEF17093
UniProt:
F6BK98
LinkDB
All DBs
Position
1136697..1138070
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AA seq
457 aa
AA seq
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MILTVKEILDATEGKLLSGDINICVSGISTDSRTIKPGDLFIPLKGERFNGEKFIDDALN
VGSASLTESTNCIRHDNKPIIFVEDTKDALHRIAKYYRSKFNIPFIAVTGSSGKTTTKDM
IYDVLSMKYNVLKTIGNFNNEIGLPLTLFTLNDDHDMAVVEMGMSGFGEIRRLKNIASPN
VAVYTNIGVAHIEKLGSRENILKAKSELIEDFKNGDTVVINADDDMLIKMLEKKGPKFVT
YGINNGDIKAFDIELNEESSKYKVLIDGYVLDVELNVPGKHNIYNSLAAICIGIQFDVNK
EDIRKALAKFQPSAMRLNIIDVAGIKIINDVYNANPSSMKAALSVLGGYTERRKVAVLGN
MLELGQYKDIAHREVGEYVKENDIDVLITVGDYALKIADGAIEKGMNNDNVFRCANNAEA
IDVIKNIMKESDIFLVKGSRGMEMEEIVKFLQESAYK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
ttgattttaacagttaaagagatattagatgcgacagaagggaaattgctatctggagat
ataaatatatgcgtaagcggtataagtaccgattcgaggacaattaagcctggagatttg
tttatacctttaaaaggtgaaagattcaatggagagaaattcatagatgatgccttaaat
gtaggttctgcctcacttacagagtctaccaattgtataaggcacgataataaaccgatt
atatttgtcgaagatacaaaagacgctttgcacaggatagctaaatattatagaagtaaa
ttcaatattccgtttattgctgtaactggcagcagtggaaaaactacaactaaggatatg
atttacgatgttttatcgatgaagtacaatgtcttaaagacaatcggaaatttcaacaac
gagatcggcttgccccttaccttatttacgcttaatgatgatcatgatatggctgtcgtt
gaaatgggaatgagcggttttggcgaaataagaaggttaaaaaacattgcatctcctaat
gttgcggtatatacaaacattggagttgctcacattgaaaaattaggttctcgtgaaaat
atattaaaggcaaaatcagaacttattgaagattttaaaaatggcgatacagtcgtaatt
aatgcagatgatgatatgttaataaaaatgcttgaaaaaaaaggtcctaaatttgtgaca
tacggcataaataatggcgatattaaggcctttgacatagaattaaatgaagaatcttca
aaatacaaggttttgatagatgggtatgtattagacgtagaattaaacgtacctggaaaa
cacaatatatacaattctttagcggcaatttgtataggaatccaatttgatgtcaataaa
gaagatataaggaaagcactggctaagtttcaaccaagtgctatgagattaaatataata
gatgtcgcaggtattaaaattataaacgatgtgtataatgcaaatccttcatctatgaaa
gctgctttgtcagttttaggtggatatacagagagaagaaaagtagctgttttaggcaat
atgttagagttaggacagtataaagacattgcacatcgagaggttggcgagtacgtgaag
gaaaatgacattgatgtacttataacagttggagattatgctttaaaaatagctgatggg
gcaatagaaaaaggaatgaacaatgataatgtctttagatgtgctaataatgcagaagcc
attgatgtcataaaaaatattatgaaagaaagtgacatatttttagttaaaggttcaaga
gggatggagatggaggaaatcgtgaaatttttgcaggagagtgcttataaatga
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