Ursus arctos (brown bear): 113240945
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Entry
113240945 CDS
T05909
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00140
Steroid hormone biosynthesis
uah01100
Metabolic pathways
uah05215
Prostate cancer
Module
uah_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
113240945 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
113240945 (SRD5A2)
Enzymes [BR:
uah01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
113240945 (SRD5A2)
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Gene cluster
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
113240945
NCBI-ProteinID:
XP_026334258
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All DBs
Position
Unknown
AA seq
254 aa
AA seq
DB search
MPVPCQQSPVLAGSATLAALGALVLYLAKPSGYGKYSESLMPAATRLPARAAWFLQELPS
FAVPAGILAQQPRSLFGQPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLVRGFVFCM
GNGLLQGYYLIYCAEYPAEWYTDVRFTLGVFLFILGMGINIQSDYILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLALRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcccgttccctgccagcagagcccggtgctggcgggcagcgccactttggccgccctg
ggggcgctggtcctgtacctcgcgaagccctccggctacgggaagtactcggagagcctg
atgcccgccgctacccgcctgcccgcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatccttgcccagcagccgcgctcgctcttcggccagcctgcg
acggtgctcctgggcctcttctgcgcacattatttccacaggacatttgtttactcattg
ctcactagagggaggcctttcccagttgtgttccttgtcagaggttttgtcttctgcatg
ggaaatggacttctccaaggctactatctgatttactgtgctgaataccctgctgagtgg
tacacagacgtacggtttaccctgggcgtcttcttatttattttgggaatgggaatcaac
attcagagtgactatatattgcgccagctcaggaagcccggagaagtcatctataggatt
ccacaaggtggcttgtttacgtatgtttctggagccaatttccttggggagatcattgaa
tggatcggctatgccctggccacttggtccctcccagcacttgcatttgcgtttttctca
ctttgtttcctggcgctgcgagctttccaccatcatagattctacctcaagatgtttgag
gactaccccaaatctcggaaggccctcattccatttattttttaa
DBGET
integrated database retrieval system
