Ursus arctos (brown bear): 113241420 Help Entry 113241420         CDS       T05909                                  Name (RefSeq) SCO-spondin   KO K24434   SCO-spondin Organism uah  Ursus arctos (brown bear) Brite KEGG Orthology (KO) [BR:uah00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:uah04990]     113241420 Domain-containing proteins not elsewhere classified [BR:uah04990]  Thrombospondin domain-containing proteins   Other thrombospondin domain-containing proteins    113241420 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TSP_1 TSP1_spondin VWD TIL C8 Ldl_recept_a VWF Pacifastin_I F5_F8_type_C VWC TSP1_ADAMTS Motif Other DBs NCBI-GeneID:  113241420 NCBI-ProteinID:  XP_048069099 LinkDB All DBs Position Unknown AA seq 5243 aa AA seqDB search MAPAACSSDPPLLSTPIPPGSAQTHNRRPRFRRTRCDTRGGSRVPWGSEGWPWPKETELS LSENGPFEAEIGVGALSRVPREKAGLERRHGEGGPMVGPREMPSVALVPSSFLALGGTQA SQPPKGDLGGSTMLLPALLFGMAWTLANGRWCEHTETFLVEEEVTPRQEDLVPCTSLYHY QRLGWQLDPSWSGRAGLCPIYKPPETRPAARNRTVRACCPGWGGTHCTLALAGASPGGHC FATQQCQPQAGSANASAGSLEECCAWPWGHSWRDGSSWACLSCSSRHLPGNAPAPALLQP LAGAVAQFWSQRQQPSATCATWSGFHYRTFDGRHYRFLGRCTYLLAGAADATWAVHLTPR GHCPQPEHCQLARVMMGPEEVLIQGKNVSVNGKLVPDAESQLLHGLSLQWQGDWLVLSGG LGVTVRLDRSSSVSISVDYELQGQTQGLCGVYNGQPEDDFLEPGGRLAVLAATFGNSWRL PDSEPGCLDSVEAAQGCEDPPSGTEAGMEAEAQDVCHQLLDSPFRECHAQVPPAEYHQAC LFAYCSGAPAGSGREARREAVCTTLANYAQECAKQHIHVGWRKPGFCERLCPGGQLYSDC TSACPPSCSAVGEGGEGSCREACVSGCECPPGLFWDGALCVPAARCPCYHRRRRYAPGDT VRQLCNPCVCQDGRWLCAQAPCPAECAVGGDGHYLTFDGRSFSFRGSPGCRSSLVQDLKG QLLIVLEHGACDTGSCLHAISVSLGDTHIQLRDSGAVLIDGQDVGLPWSGPKGLRVSRAS SAFLLLRWPGAQVLWGVSDPATYITLDPRHAHQVQGLCGTFTWNQQDDFLTPAGDVETSI AAFASKFQAAGEGRCPSEDSAPLSPCGTHTQRHVFAEAACAVLRGPTFQECQGLVDREPF HLRCLAAVCGCAPGKDCLCPVLAAFARRCAQEGALSLWRTQTLCPVLCPAGQEYQECAPA CGQNCGEPEDCGELGSCVAGCNCPPGLLWDPEGECVPPSLCSCQLGTRRYAPGSATMKDC NHCVCQERGVWNCSAHRCGPQQTFCPRDLVYIPGACLLTCDSPGASHPCPPDSTGSCVCP PGTVLLNERCVPPELCPCRHGGQWYPPNATIQEDCNICVCQGRQWHCTSHRCGGWCQASG APHYVTFDGLAFTFPGACEYLLVREASGRFTVSAQNLPCGASGLTCTKALTVQLQSTAVH MLRGRAVMVNGVSITLPKVYTGPGLSLRRAGLFLLLTTRLGLSLLWDGGTRVLVQLSPQF RGRVSGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWHLSPFCPEPGDLLHPCTVNAHRA SWARTRCGVMLQSLFARCHGEVPPQQHYEWCVHDACGCDSGGDCECLCSAVATYADECAR HGFHVRWRSQELCPLQCEGGQVYEACGPVCPPTCHDHGPEPGWHCQAVACVEGCFCPEGT LLHGGVCLEPASCPCESGGSFFPPGTVLQKDCGNCTCQESQWLCGSTGTRCEEPAPGCVE GEAPCQESGHCVPHTWLCDNQDDCGDGSDEEGCATPGCGEGQMSCSSGHCLPLALLCDGQ DDCGDGTDEQGCPCPQGSLACTDGRCLPLALLCDGHPDCPDAADEEACLGQLNCTPGEVS CVDGTCVGAILLCDGIWDCPDGADEGPGHCPFPSLPTPPAGTLPGPSAGFGETAPTPLAS TSPAPPCGPLEFRCGSGECAPRGWRCDGEEDCADGSDERGCAWPCAPHHAPCARGPHCVS PAQLCDGVPHCPDGSDEGPNACEGMTAPGGPNGTRVPCPEYSCPDGLCISFQLVCDGQPD CGFAGELGPSPEEQGCGAWGPWNSWGPCSRTCGPGVQSRSRHCSPPDLPVLQHCLGPEHQ TQACFTAACPVDGEWTSWSPWSPCTEPCMGTTTRQRQCHPPQNGGRTCAMLPGGPPTTHQ TRPCPQDGCPNATCSGPLVFWPCAPCPLTCDEISAQAVCEANRPCSGPGCWCPAGQVLGS DGRCVWPRQCPCLLDGTLYRPGQRIKADCQLCTCQDGRPQRCRPDPDCAVNCGWSSWSPW AECLGPCGSENIQWSFRSPNNPRLSGQGRQCRGIRRKARRCRTEPCAGCEQQGRPQAVGE RWREGPCGVCQCLHNSTVRCSPYCPLGSCPQDWVLVEGVGGSCCHCALPGENQTVHPLAT PAPSPALSAQIGSPLVAYVLPLPGDPCYSPLGLALLPEGSLKLESPTQAALLGAPTKRPG FLGRSTQRHTRPPYLQLDLLLPRNLTGIIVQGAGSSAFLQFSSDGLHWHNYTDILPGILP PAKLFPRNWGDGAPTVQMFGQMVQAQHVRVWPHVPRGDPNQSIPLWVELLGCEPVSPLAA PPCPGGGHRCASGECAPRGEPCDGAKDCEDGSDEEGCVPLPAATGRVWSTARTPALSSVQ PGQLPSRPTEGLAEAERWHPSRGSPIAPTGKEPATQAPASEALRLSPRESVQTMTTTPTS QVTPVAPAGQSVAPEPFPPVRCSPGQVPCEVLGCVEQGQLCDGREDCLDGSDERHCASPV PFTVPTTALPGLLASRAPCSPSQLSCGSGECLPAERRCDLRPDCQDGSDEDGCVDCGLAP WSGWSSCSRTCGPGLAFQRRDLLRPPLPGGSCPSDRLRSQSCFVQACPVAGEWAVWGAWG PCSVSCGGGHRSRQRSCVDPPPKNGGAPCPGTSHEGAPCALQPCTGDTDCGLGRIHISAE LCRKGLVPPCPPSCLDPEANRSCSGHCLEGCRCPPGLLLHDAHCLPLSECPCLVGEELKP PGVPFLLDNCSRCTCEKGALLCEPGGCPVPCGWSAWSSWGPCDRSCGSGVRARFRSPSNP PAASGGAPCEGDRQELQACHVECGTEAPGWTPWTPWSACSRSCLTIGGGPGWRSRSRLCP SPGDTSCPGEATQEEPCSPPVCPVPSSWGLWAPWSACSAPCDGGIQRRGRSCSGSTPGDP ECPGPHSQTRDCNTQPCTAQCPGDMVFRSAEQCQQDGGPCPQLCLAQDPGVECTSFCAPG CACPPGLFLHDASCLPRSRCPCQWHGQLYAPEARAQLDSCNNCTCVSGEMVCTSEPCPVA CGWSPWTPWSPCSRSCDVGVRRRFRAGTAPPAAFGGAACQGPSMEAEFCSLRPCRGPGGE WGPWSPCSVPCGGGYRNRTRNGGLHGRVDFSACGLQPCAGPVPGVCPRGKRWLDCAQGPA SCAELSAPQGTDQTCHPGCYCPSGTLLLNNVCVPSQDCPCAHGGRLYPPGSVVLRLCENC SCVSGLITHCTSWPCEEGQPRWSPWTPWSECSASCGPARRHRHRFCSEPPTTDPSIPALL SPPTLPTPLCPGPDAEEEPCLLPGCDRAGGWGPWGPWSGCSRSCGGGLRSRIRACDQPPP QGLGDYCEGPRAQGEACQALPCPVTNCTAIQGAEYSPCGPACPRSCDDLVHCVWHCQPGC YCPPGQVLSADGAFCVQPSHCGCLDLLSGERHRPGARLPRPDGCNYCTCSEGRLNCTDLP CPVPGGWCPWSEWTACSQPCRGQTRTRSRACACPAPQHGGTPCPGKAGDAGAQHQKESCP SSPECPVDGAWSPWGLWSPCDPCLGQSHRSRECIWPPTPEGGRPCPGGYRQSRPCQDNST QCPDCGGGQGLLPCGWPCPRSCQDLSPGSVCQPGPTSCQPSCGCPPGQLSQDGLCVPPVH CRCHYQPGAMGIPENESRSAGPGLSSWESLEPGEVVTGPCDNCTCTEGILQCQEVPGCPG PGVWGTWGPWEDCSVSCGGGEQLRTRRCARPPCPGPARQSRTCHTQVCREAGCPAGRLYR ECPPSDVCPFSCTHVTRQVACFSDGCEEGCHCPVGTFQHRLSCVQECPCMLTASLLQELG AAGADPGARPPILGQGGQPLGPGDELGSGQSFRTGCRNCSCVHGQLSCSVGDCSKAADGF SPWGPWGPCSRSCGGLGTRTRSRHCVRPSPAPGSQGCEGPRQDLKYCPSPGCPGAGGSTV EPVTSLPVGWGPWSPWSPCSHTCTDPTNPAWRSRTRLCLANCTGGDTSQERPCNLPSCTE LPLCPSPGCAAGNCSWTAWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPDILTAYQER RFCNPRACPVPGGWSRWSPWSWCDRSCGGGRSLRSRSCSSPPPKNGGAPCVGERHHIRLC NPLPCEEGCPAGTKMVSCANRCPRRCSDLQEGIVCQDGQGCQPGCRCSEGFLEQDGGCVP TGHCECTDAQGQSWAPGSQHQEACNTCTCEAGRLSCTAQPCPAPAHCAWSRWSAWSPCSR SCGPEGQQSRFRSSTSGSWAPECREEQSQSQPCPQPPCPPLCLHGARLHTLGDSWLQGEC QQCSCTPEGIICEDVECAVPGAWTLWSPWSECPVSCGGGNQVRTRVCMASAPDHSGGPCL GPGTQTQRCGWQPCLGLLEACSWGPWGPCSRSCGPGLASRSGSCPCPLAEVNPTCNGTFL HLDAQACYPGPCPEECVWSSWSSWTRCSCQVLVQQRYRHQHPAPGAVGAGAGSPCTRLDG HFRPCPVANCSEDSCTPPFEFQACGSPCAGLCATHLSHQLCQDRPPCQPGCYCPAGLLEQ AGGCIPPEQCSCLHLTEEGARVTLAPGDRLHLGCKECECQRGELQCTSQGCQGFLPLSGW SEWSPCGPCLPPGVLAPASRTALEERWSQHPAGLSPTLAPSLASEQHRHRLCLDPETGRP WAGDPDLCTAPLSQQRLCPDPGACHDLCQWSPWGPWSPCQVPCSGGFRLRWRKAGGPPGG GCRGPWAQTESCNVGPCPGESCEARDTVPTLDCANRCPRSCADLWDRVQCLQGPCRPGCR CPPGQLIQDGHCVPISSCRCGLPSPNASWVVAPAEVAQLDCKNCTCINGSLMCPHHECPV RGPWSAWSSCSAPCGGGTMERHRSCEEAPAGVPCQARDTEQRQECNLQPCPDCLPGQVLR ACASTCPRLCSHLQPGALCEQEPCQLGCGCPGQQLLHNGMCVPPAACPCTQISLPWGLTL PLEEQARELPAGTVLTWNCTRCVCQDGAFNCSLADCHECPSGEMWQQVPPGELGPCERTC REPNATETWGNCSAGPAPGCVCQHGHLRNQAGLCVPAHHCECWRHGRPHPPGSEWQEACE SCRCLRGRSVCTQHCAPLTCAQGEVIVQEPGSCCPTCRQEILEEQPASCRHLTELRNLTK GPCYLEQVEVSYCSGHCPSSTNVMPEEPYLQSQCGCCSYSLDPESPVRILTLRCPGGRTE PVVLPAIRSCQCSACLGGDFSKH NT seq 15732 nt NT seq  +upstreamnt  +downstreamnt atggcgcccgctgcctgtagctcggacccgcccctgctctccactccgattccacccgga tccgctcagacccacaaccgccgaccccgattccggaggacccgatgcgacacccgcggc gggagccgggtcccctggggcagcgaggggtggccgtggccgaaggagacagagctgagc ctcagcgagaacgggccctttgaagcagaaattggggtgggggcattgagccgggtcccc agggagaaggcggggctggagaggaggcacggggagggcggaccaatggtgggcccaaga gaaatgcctagcgtggctctggttcccagcagcttcctggccctaggtgggacccaagcc tcacagccccccaaaggtgacctggggggcagcaccatgctgctgcctgccctcctcttt gggatggcatggaccctggctaacgggcggtggtgtgaacatacggaaaccttcctggtg gaggaggaagtgaccccccgccaggaggacctggtgccctgcaccagcctctaccattac cagcgcctgggctggcaactggatccgtcctggagtggacgtgccgggctctgtcccatc tacaagcccccagaaacccggcctgctgcaaggaaccggacagtgagggcttgctgccca ggctgggggggcacccactgcacgctggcccttgcaggagccagccctgggggccactgc tttgccacgcagcagtgccagccgcaagcaggctcagctaatgcttctgcaggaagcctg gaggagtgctgtgcttggccttggggacacagctggcgggatggcagctcctgggcctgc ctcagctgctctagccgacacctcccaggcaacgctcccgcgccagccctcctgcagccc ctggcgggggccgtggcccagttctggagccagcgccagcagccgtcggccacctgcgcc acctggtcaggcttccactaccgaacctttgatgggcgccactaccgcttcctgggtcgc tgcacctacctgctggcaggggccgctgatgccacctgggctgtccacctcacgcccagg gggcattgcccccagcctgagcactgtcagctggcccgagtaatgatgggacccgaggag gtgctgatccagggcaaaaacgtctctgtgaacgggaagctggtacctgatgcggagtct cagctgctccacgggctaagcctgcagtggcaaggggactggctggtgctgtcaggtggc ctgggggtcactgtgcgcctggacaggtccagttcggtctccatttctgtggactatgag ctccagggacaaactcaaggtctctgtggagtctacaatggccagcctgaggatgacttt ctggagcctggagggagactggctgtgttagctgccacctttgggaattcctggaggctc cctgactcagagcctgggtgtctggattccgtggaggcagcccagggctgtgaggacccc ccaagcggcacagaggcaggcatggaggctgaagcccaggatgtgtgccaccagctgctg gacagtccattcagggaatgccacgcccaggttccccctgctgagtaccaccaggcctgc ctctttgcctactgctctggggccccagcaggcagtgggcgagaggcccgtcgggaagcc gtgtgcaccaccttggccaactatgcccaggagtgtgccaaacagcatatccacgtgggc tggaggaagccaggcttctgcgagcgtctgtgtcctgggggccaactgtactcggactgc acctcggcctgcccacccagctgctcggcagtgggtgaaggaggggaggggtcctgccgg gaagcgtgcgtgagcggctgcgagtgcccgcccggcctcttctgggacggcgccctctgt gtgcctgcagcccgctgcccctgctaccaccggcgccggcgctacgccccgggagacacc gtgcgccagctgtgcaacccgtgcgtgtgccaggacggccgctggctctgcgcgcaggcg ccgtgcccagccgagtgcgcggtgggcggggacggccattacctcaccttcgatgggcgg agcttctccttccgcggcagcccgggttgccgctccagcctggtgcaggacttgaagggg cagctgctgattgtgctggagcacggggcctgtgacactgggagctgcctgcacgccatc tctgtctccctgggggacacccacatccagctcagagactcaggggctgtgctcattgat gggcaggatgtgggcttgccgtggagtgggcctaagggcctcagggtctcccgcgcctcc tccgccttcctactgctgcgctggcctggggcccaggtcctctggggagtgtctgaccct gcaacctacatcactctggacccccgccatgcccaccaggtgcagggtctgtgtggcacc ttcacctggaaccagcaggatgacttcctaacacctgctggcgacgtggagaccagcatt gcagcctttgctagcaagttccaggcagcaggcgagggaaggtgcccctcagaagacagc gccccactttccccctgtggcacccacactcagcgccacgtttttgcggaggcagcttgt gctgtcctgcgtggcccaaccttccaggaatgccaaggcctggtggacagggagcccttc cacctgcgctgcttggcagccgtgtgcggctgtgctcctggcaaggactgcctgtgccct gtgctcgctgcctttgctcgtcgctgtgcccaggagggtgccctgtctctctggaggacc cagacactctgccctgtcctgtgtcctgcgggccaggagtaccaggagtgtgccccagcg tgtggtcaaaactgtggggagccagaagactgtggggagctgggcagctgtgtggctggt tgtaactgccccccaggactgctgtgggaccccgagggcgagtgtgtgccccccagcttg tgctcctgccagcttggaactcgtcgctatgcccctggcagtgccaccatgaaggattgc aaccactgtgtctgccaggagaggggcgtctggaattgctctgctcaccgctgtggtccc cagcagacattctgcccccgtgaccttgtctacatccctggtgcctgcctcctcacctgt gacagccctggtgccagccacccctgccccccggacagcacagggagctgtgtctgtccc ccaggcaccgtgctgctgaacgagcgctgcgtgcctcctgagctctgcccctgccgtcac ggcgggcagtggtatccgcccaacgctaccatccaggaggactgcaacatttgcgtatgt caggggcggcagtggcactgcaccagccaccggtgcggcggatggtgccaggcgtctggt gccccccactacgtgaccttcgatgggctggctttcaccttccctggagcctgcgaatat ctgctggtgcgagaggccagcggccggttcaccgtctctgcccagaacctgccctgtggg gccagcggcctcacctgcaccaaggcgctgaccgtgcagctacagagcactgctgtgcac atgctcagaggccgggcagtgatggtgaatggggtgagcataacactccccaaggtctac acgggcccggggctgagcctgcgtcgcgctggtctcttcctgctgctcacgacccgcctg ggcctcagcctactctgggatggaggcacccgggtcctggtgcagctgtccccgcagttt cgcggccgtgtgtctgggctgtgtggagattttgatggagatgccagtaatgacctgcgg agccgccagggggtcctggaacccacagctgagctggctgcccactcctggcacctgagt ccgttctgccccgagccaggagacctgctacacccctgcaccgtgaatgcccaccgggcc agctgggcacgcacccgctgcggggtgatgctgcagtcgctctttgcccggtgccatgga gaggtgcccccacagcagcactacgagtggtgtgtgcatgatgcctgcggctgcgattca gggggcgactgtgagtgtctctgctcggccgtagccacctatgcagacgagtgtgcccgg catgggttccacgtgcgctggcgcagccaggagctctgccctctgcagtgtgaagggggc caggtgtacgaggcctgtggccccgtgtgtccccccacctgtcatgaccatggtcctgag ccagggtggcactgccaggctgtcgcctgtgtggagggctgcttctgccccgaggggact ctgctgcatggaggagtctgcttagaacccgcttcctgcccctgtgagtcagggggcagc ttcttcccgccggggactgtgctgcagaaggactgtggcaactgcacatgccaggaaagt cagtggctttgcgggagcaccgggacccgctgtgaggagccggcgcctggctgtgtggag ggggaggccccgtgccaggagagtgggcactgtgtgccccacacgtggctttgtgacaac caggatgactgtggcgatggctcagacgaggagggctgtgccaccccaggctgtggggag gggcagatgtcttgcagctccgggcactgcctgcccctggccctgctctgtgacgggcag gacgactgcggagacgggacggacgagcagggctgcccatgcccccaaggatcactggct tgcactgacgggcgctgcctgcctctggccctgctctgtgacgggcatcccgactgtcct gacgccgcggatgaggaggcctgtctggggcagctgaactgcactcctggggaggtgtcc tgcgtggatggcacttgcgtgggggccatcctgctgtgtgacggaatctgggactgccca gatggagccgacgagggacctggtcactgccccttcccttcgctgcccactcccccagct ggcactctgcctggcccttctgctggctttggggagactgcacccactcccctggccagc accagccccgcgccgccctgcggccccctcgaattccggtgcggcagcggcgagtgcgcg ccccggggctggcgctgcgacggcgaggaggactgcgccgacggcagcgacgagcgcggc tgcgcctggccctgcgccccgcaccacgcgccctgcgcccgcggcccacactgcgtgtcc ccggcgcagctgtgcgacggcgtgccgcactgccccgatggctcggacgagggccccaac gcctgcgaggggatgacagccccaggaggccccaatgggaccagggttccctgcccggaa tactcctgccctgatggcctctgcatcagtttccagctggtgtgtgatgggcagcctgac tgtggattcgcaggggagctagggccttccccagaagagcagggctgtggggcctggggc ccctggaactcatgggggccatgcagccggacgtgtgggcctggggtgcagagccggagc cgccactgctccccccctgatctcccagtgctgcagcactgcctaggccctgagcaccag actcaggcctgcttcacggctgcctgcccagtggatggcgaatggacctcctggtctccc tggtccccgtgcactgagccatgcatgggcaccacgacccgtcagcgacagtgccaccca ccccagaatggaggccggacctgtgccatgctgccagggggccctcccaccacccaccag accaggccctgccctcaagatggctgccccaatgccacctgctccgggccgttggtgttc tggccctgtgccccctgccctctgacttgtgacgaaatctcggctcaggctgtgtgcgag gctaaccggccctgcagcggcccaggctgctggtgccctgcaggccaggtgctgggcagc gatgggcggtgtgtgtggccccggcagtgcccctgcctgctggatggcaccctgtaccgg cctggccagcgcatcaaggccgactgccagctctgcacctgccaggacgggcggccccag cgctgtcggcccgacccagactgtgccgtgaactgtggctggtcctcctggtccccctgg gctgagtgcttgggcccctgtgggagcgagaacattcagtggtccttccggagccccaac aacccccgcctctccggccaaggtcgccagtgccggggcatccgccgcaaggcccgcagg tgccggacggagccctgtgcgggctgtgagcagcagggccggccccaagccgtgggggag cgctggcgagagggcccctgcggagtctgccagtgtctgcacaacagcaccgtgcgctgc tccccctactgcccactgggcagctgcccccaggactgggtcctggtggagggagtggga ggctcgtgttgtcactgcgccctgcctggtgagaaccagacggtccaccccctggccact cctgccccctctccagccctcagtgcccagatcggatcgcctctggtggcctatgttctg cctctgcctggagacccctgctattctccgctgggcttggccctactccctgagggaagc ctgaagctggagtcccctacccaggctgccctcctgggggctcccaccaagaggcctggt tttctgggtcggagcactcagcggcatacccggcccccctacctgcagctggacctgctg ctgccccggaacctcactggcatcatagtgcagggggctgggtcctcggccttccttcag ttcagcagcgatggtctacactggcacaactatactgacatcctgcctggtatcctgccc ccagccaagcttttccctaggaactggggtgatggggcccccacagtgcagatgttcggc cagatggtgcaggcgcagcacgtccgggtgtggccgcacgtcccccgcggtgaccccaac cagagcatccccctgtgggtggagctgctgggctgtgagccagtgtccccgctggctgcg cccccgtgcccagggggtgggcaccgctgtgccagtggcgaatgtgctccacggggggag ccgtgtgacggggcaaaggactgtgaggatggctccgatgaggagggctgcgtgcccctg cccgcagccaccggcagagtctggtccacagccaggacccccgcgctctcctccgtgcag cccggacagctgccctcccggcccacggagggtctggcagaggctgaacgctggcatccc tcgcgagggtcacccatagcccccacagggaaggagccagcgactcaggccccagcctcc gaggctcttcggttgagtcctagggaatctgtgcagaccatgaccaccacccccacatcc caggtgaccccagtggccccagctggccagagcgttgccccggagcccttcccacctgtg cggtgcagcccgggccaggtgccctgtgaggtgctgggctgcgtggagcaggggcagctg tgtgacggcagggaggactgtctggacggctccgacgagaggcactgtgcgagccctgtg cccttcacggtgcccaccacagccctgcctgggctgctggcctcgcgagccccctgctcc ccgagccagctgagctgtggaagtggggagtgcctgccagctgagcggcgctgtgacctg cggccagactgccaggacggctctgacgaggacggctgtgtggactgtgggctggcgccc tggtctggctggagcagctgcagccgcacctgtgggccgggcctcgccttccagcgccgg gacctgctccggcctcccctgcctgggggcagctgcccgtctgacaggctccgcagccag tcctgcttcgtgcaggcctgcccagtggccggggagtgggctgtgtggggggcttggggg ccctgcagcgtctcctgtgggggtggccatcggagtcgtcagaggagttgtgtggacccc ccgcccaagaatggtggtgctccctgccccgggacctcccacgagggggcaccctgcgcc ctgcagccctgcacaggggacacagactgtgggctgggccggatacatatcagcgctgag ctgtgcaggaaggggctggtgcccccgtgtccaccctcctgcttggatcctgaggccaac agaagctgcagcggacactgtctggagggatgccgctgcccccccgggctcctcctccat gatgctcactgcctgcctctctctgagtgtccttgcctcgtgggtgaagagctgaagccg ccgggggtgcccttccttctggacaactgcagccgctgcacgtgtgagaagggggccctg ctgtgtgaaccagggggctgccccgtgccctgcggctggtcagcctggtcctcctggggt ccctgtgaccgctcctgcggctctggagtgagggccaggttcagatccccttccaaccct ccggctgcttccgggggcgccccgtgtgaaggcgacaggcaggagcttcaggcctgccac gtggagtgcgggacagaggcgccgggctggaccccctggacaccctggtccgcctgctcc cggagctgccttaccattggaggaggccccgggtggcgcagtcgttcccggctctgcccc agccccggggacacatcctgcccaggagaggccacccaggaggagccctgcagcccccct gtgtgcccagtgccgagctcctggggtctgtgggctccctggtctgcctgctcagccccc tgtgatggaggcatccagagacgtgggcgcagctgctctggctccacccccggggacccc gagtgcccgggacctcacagccagaccagggactgcaacacgcagccctgcacagcccaa tgcccgggggacatggtgttccgctcagcagagcagtgccagcaggatgggggcccctgc cctcagctgtgcctggctcaggaccctggggtagagtgcaccagcttctgcgcccctggc tgtgcctgcccccccggcctcttcctgcacgacgccagctgcttgccccgcagtcgatgc ccctgccagtggcacgggcagctctacgccccagaagcacgggctcagctggattcctgc aataactgcacctgtgtctccggtgagatggtgtgcacctcggagccctgcccagtggcg tgtggctggagcccctggaccccatggagtccctgcagccgcagctgtgacgtgggcgtt cggcggcgcttccgggcgggcactgcgcccccagctgccttcgggggtgctgcgtgccag ggccccagcatggaggctgagttctgcagcctgaggccgtgtcggggtcctggtggggag tggggcccctggtctccgtgctccgtgccctgcggcggtggctaccggaaccgcacccga aacggtggcctgcacggccgtgtggacttctctgcctgtgggctgcagccctgtgcaggg cccgtgcctggcgtgtgtcccaggggcaagcggtggctggactgtgcccagggccctgcc tcctgtgcggagctcagtgccccgcaagggactgaccagacctgtcaccccggctgttac tgcccatccgggacgctcctgctgaacaacgtgtgtgtgccctcccaggactgcccctgt gcccatggggggcgcctttatcccccaggcagtgtggtgcttcgtctgtgcgagaactgc tcctgtgtttctgggcttatcacgcactgcacctcctggccctgtgaggagggtcagccc aggtggtcaccgtggaccccatggagcgagtgctcagcctcctgtggccctgcccgacgc caccggcaccgcttctgctccgagccccccaccacggacccgtccatcccagcgctgcta tccccaccaacactgcctacccctctttgccccggccccgacgctgaggaggagccctgc ctcctgccagggtgtgaccgagctggaggctggggtccttgggggccctggtctggctgt agccggagctgtgggggaggcttgcggagccggatccgagcctgtgaccagcccccaccc cagggcctgggggattactgtgaggggcctcgggcccagggagaggcctgccaggctctg ccatgcccagtgaccaactgcaccgccattcaaggggcagagtacagcccgtgtggccct gcctgtcctcgctcctgtgatgacctcgtgcactgcgtgtggcactgccagcccggctgc tactgccctccaggccaggtgctgagtgccgacggggccttctgcgtgcagcccagccac tgtggctgcctggacctgctgagcggggagcggcaccggccaggggctcggctgcccagg cctgacggctgcaactactgcacctgctcggaggggaggctgaactgcacagacctgcct tgcccagtgccgggtggctggtgtccgtggtcggagtggacagcgtgctcccagccctgc aggggtcagacaaggacccgctccagggcctgtgcctgccccgcccctcagcatgggggg accccgtgccccggtaaagcaggggatgcaggggcccagcatcagaaggagtcctgcccc agctcccccgagtgcccagtggatggagcctggagcccgtggggactgtggtctccctgt gacccgtgcctggggcagtcccatcggagccgggagtgtatctggccccccacccctgag ggaggcaggccctgccctgggggctacaggcagagtcggccctgccaggacaattccacg caatgcccagactgtgggggtggccagggtcttcttccctgcgggtggccctgtccccgc tcctgtcaggacctgtctcctgggagcgtgtgccagccaggcccgacgagctgccagccc agttgtggatgcccccccggccagctgtcccaggatggcctttgcgtgcctcccgtccac tgccgctgccactaccagcccggagccatggggattcctgagaacgagagccggtcagca gggccagggctcagctcctgggagagcctggaacctggagaggtggttactgggccctgt gacaactgcacctgtacggagggcatcctgcagtgccaggaggtgcctggctgccccggc cctggggtttggggtacctggggcccctgggaagactgcagtgtctcatgcggaggaggg gagcaactccgcacccggagatgtgcccgccccccctgccctgggcctgcccgccagagc cgcacctgccacacccaggtctgcagagaggcaggctgcccagctggacgtctgtaccgg gagtgcccgcccagcgacgtgtgccccttctcctgcacccacgtcactcggcaggtggcc tgcttctccgatggctgtgaggagggctgccactgccccgtgggcaccttccagcaccgc ttgtcctgtgtgcaggagtgcccctgcatgctgacagcttcactgctgcaggagctggga gctgccggcgctgaccctggggctcggccccccattctgggacagggtggtcagcccctt gggcctggggatgagttgggctcaggccagagctttcgtacaggctgcaggaactgctcc tgtgtgcatgggcagctgtcttgctcggtgggggactgctccaaggctgctgatggcttc agtccctgggggccatggggcccatgctcccgctcttgtggtgggctgggtacccgaacc cgcagccgccactgtgtgcggccgtcccccgctccaggcagccagggctgcgaagggccc cgccaggacctcaagtactgccccagcccaggctgcccaggggccggagggtccacagtg gagccagtgacaagccttccagttggctggggcccatggtccccatggtccccctgttct cacacctgcacagaccccaccaaccctgcttggcgcagccgcactcgcctctgcctggca aactgcaccgggggggacacgtcacaggagcgcccttgcaacctgccctcctgcacagag ctgcccctgtgccccagccctggctgtgcggctgggaactgttcctggactgcctgggcc ccgtgggaaccttgctcccgaagctgcggcgtgggccagcagcgccgccttcgggcctac cgtccgccaggacccggcgggcactggtgtcccgacatccttaccgcttaccaggagcgc cgcttctgcaacccgcgagcttgcccagtgcctggaggctggtcacgttggagtccctgg tcctggtgtgaccggagctgtggggggggccgatccctgaggagccgcagctgctcaagc cccccacccaagaacgggggtgccccctgtgtgggggagaggcaccacattcgactctgc aaccccttgccctgtgaggagggctgcccagcaggcacgaagatggtcagctgtgccaac cgctgcccccgccgctgctcagacctccaggaggggatcgtgtgtcaggatggccagggc tgccagccaggctgccgctgctctgagggcttcctggagcaggatggtggctgcgtgccg actgggcactgcgagtgtacagacgcccagggccagagctgggccccaggcagccagcac caggaggcctgcaatacctgcacctgcgaggccgggcggctctcctgcacagctcagccc tgcccagcacctgcccactgcgcctggagccgctggtcagcctggagtccctgcagccgc tcgtgtggtcccgaggggcagcagagccgctttcggtcctccacatcgggctcgtgggcc ccagaatgtcgggaagagcagtcgcagagccagccctgccctcagcccccgtgcccaccc ctgtgcctgcacggtgcccgcctccacaccctgggggacagctggctgcagggcgagtgc cagcagtgctcctgcaccccggagggcatcatatgtgaagacgttgagtgtgcagtaccc ggggcctggacgctctggtccccctggtctgaatgccctgtctcctgtggaggtggaaac caggttcgcacccgggtctgcatggcctcggcccctgaccacagcgggggcccctgcctg ggccctggcacccagacccagcgctgtggatggcagccttgcctggggctgctggaggcc tgctcctggggcccatgggggccctgttcccgcagctgcggcccaggcctggcctcccgc tctgggtcctgcccctgcccactggctgaagtcaaccccacctgcaacggcaccttcctc cacctggacgcccaggcctgctacccagggccctgcccagaggagtgtgtgtggagtagc tggagcagctggacgcgatgctcctgccaggtgctggtccagcagcgctaccggcaccag cacccagcgcccggagcggtaggggccggggcgggctctccctgcacgcgactggacggc cacttccggccctgccccgtcgccaactgctcggaggacagctgcacacctccctttgag ttccaggcctgtgggtccccctgtgctgggctctgcgccacacacctgagccatcagctc tgccaggaccggccgccctgccagcctggctgctactgccctgcgggcctgctggagcag gccgggggctgcattcccccagagcagtgtagctgcctgcacctcacagaagagggagcc agggtgaccctggcccccggggaccgcctgcacctgggctgcaaagagtgtgaatgccag cgcggggagctgcagtgcaccagccagggctgtcaaggttttctgcctctgagtgggtgg tccgaatggtcaccctgtggaccctgcctgccccctggcgtgctggcccctgcctccagg actgccctagaggagcgctggtctcagcaccccgctggcctctccccgactttggccccc tcgctggcttcggagcagcaccgccatcgcctctgtttggaccctgagacggggaggcca tgggctggggacccagacctctgcaccgcaccactcagccagcagcgcctctgtccggac cctggggcctgccatgacttatgccagtggagtccttgggggccctggagcccctgccag gtgccctgcagtgggggtttccggctacgctggagaaaggcaggaggcccccctggaggg ggctgccgggggccatgggctcagactgagagctgcaacgtggggccctgcccaggggag agctgcgaagcccgggacactgtgcccacccttgactgtgccaaccgatgccccagaagc tgtgctgacctctgggaccgtgtgcagtgtctgcagggaccgtgccgcccaggctgccgc tgcccccctggccaactgatacaggatgggcactgcgtgcccatctcctcctgccgctgt ggccttcccagccccaatgcctcatgggtggtggccccagccgaggtggcacagctggac tgcaaaaactgcacctgtatcaacgggtccctgatgtgcccacaccacgagtgcccggtc cgtgggccttggtcggcgtggagcagctgctctgctccctgtggtgggggcactatggag cgacatcggagctgtgaggaggctcctgcgggggtaccatgccaggcccgggacacagag caacggcaggaatgtaacctgcagccctgccctgactgcctacctggccaggtgctcaga gcctgtgcctccacgtgcccgcgcctctgctcgcacctgcagcctggcgccctctgtgag caggaaccctgccagctgggctgcggctgccctggacagcagctgctgcacaatggcatg tgtgtgccccccgctgcgtgcccctgcacccagatctctctgccgtgggggctgaccttg ccccttgaagagcaggcccgggagcttcccgcggggactgtgctcacctggaactgtacc cgctgtgtctgccaagacggagccttcaactgctccctagccgactgtcatgagtgcccc tctggggaaatgtggcagcaggtgccccctggggagctggggccgtgcgaacggacgtgc cgggagcccaacgccacggagacttggggcaactgcagtgcggggccggccccgggctgc gtgtgccagcacgggcacttgcgcaaccaggcgggcctctgcgtgcccgcacaccactgc gagtgctggcgccatgggcgtccccacccgcctgggtccgaatggcaggaggcctgtgag agctgccgctgcctccgtgggaggagtgtctgcacccagcactgcgcccccctcacctgt gcccagggcgaggtgatcgtgcaggaaccagggagctgctgtcccacttgccgccaagag attctggaggagcagccagcctcctgccggcatctcaccgagctgcgcaacctcaccaag ggcccctgctacctggagcaggtagaagtgagctactgcagtgggcactgcccatccagc accaacgtcatgcctgaggagccgtacctgcagagccagtgcggctgctgtagctacagc ctggaccccgagagcccggtgcggatcctgaccctgcgctgtcccggcggccgcacggag cccgtggtgctgcctgccatccgcagctgccagtgcagcgcctgcttgggaggtgatttc tcaaagcactga

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