Ursus arctos (brown bear): 113241996
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Entry
113241996 CDS
T05909
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00564
Glycerophospholipid metabolism
uah00565
Ether lipid metabolism
uah00590
Arachidonic acid metabolism
uah00591
Linoleic acid metabolism
uah00592
alpha-Linolenic acid metabolism
uah01100
Metabolic pathways
uah04010
MAPK signaling pathway
uah04014
Ras signaling pathway
uah04072
Phospholipase D signaling pathway
uah04217
Necroptosis
uah04270
Vascular smooth muscle contraction
uah04370
VEGF signaling pathway
uah04611
Platelet activation
uah04664
Fc epsilon RI signaling pathway
uah04666
Fc gamma R-mediated phagocytosis
uah04724
Glutamatergic synapse
uah04726
Serotonergic synapse
uah04730
Long-term depression
uah04750
Inflammatory mediator regulation of TRP channels
uah04912
GnRH signaling pathway
uah04913
Ovarian steroidogenesis
uah04921
Oxytocin signaling pathway
uah05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
113241996 (PLA2G4E)
00565 Ether lipid metabolism
113241996 (PLA2G4E)
00590 Arachidonic acid metabolism
113241996 (PLA2G4E)
00591 Linoleic acid metabolism
113241996 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
113241996 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113241996 (PLA2G4E)
04014 Ras signaling pathway
113241996 (PLA2G4E)
04370 VEGF signaling pathway
113241996 (PLA2G4E)
04072 Phospholipase D signaling pathway
113241996 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
113241996 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113241996 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
113241996 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
113241996 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
113241996 (PLA2G4E)
04913 Ovarian steroidogenesis
113241996 (PLA2G4E)
04921 Oxytocin signaling pathway
113241996 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
113241996 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
113241996 (PLA2G4E)
04726 Serotonergic synapse
113241996 (PLA2G4E)
04730 Long-term depression
113241996 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
113241996 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
113241996 (PLA2G4E)
Enzymes [BR:
uah01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
113241996 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
113241996
NCBI-ProteinID:
XP_026335734
LinkDB
All DBs
Position
Unknown
AA seq
863 aa
AA seq
DB search
MTLQSSEGCPGLGTDVFIPQSLQEAEEDSRSERNVSEFELPRDPEPPNLPPLLPMAPWGS
EGGLSPCHLLTVKVIRMKNVRQADRVSQTDCFVSLWLPTASHERLRTRTISNCPNPEWNE
TFSFQIQSQVKNVLELSVCDEDTLTPDDHLLTILYDLTKLCFRKKTHVKFPLNPEGMEEL
EVEFLLEESPSPPESLITNGVLVSRQVSCLEVHAECRRRRKSRKMKDLLVTVKESFEHTQ
RVSCCQEPCPPNPACFHYPKYFQPCMHVDVPKSQCSRGLCCCCAHRKNSPVRQPLDCLPD
GQTVTLPVGENCELHMKSTPCPQTLDVRLGFSLCPAEQEFLQKRKPVVAQALQEVLQLEA
DLPVDEVPLIAIMATGGGTRSMTAMYGHLLGLQKLNLLNCASYITGLSGATWTMATLYRD
PDWSSKNLEPAIFEARRHVVKDKMPALFPDQLSKFQEELRQRSQEGYKVTFTDFWGLLIE
ACLGDERNESKLSDQRAALCQGQNPLPVYLTINVKDDVSNQDFREWCEFSPYEVGLQKYG
AFIPTELFGSEFFMGRLMKRIPESRMCYMLGLWSSIFSLNLLDAWNLSQSSEEFFHRWTR
ERVHDIEDEPLLPEIPKCDANVLDTAVVIPGSWLSNTFRSILTHRAFVSQFHNFLLGLQL
HTDYLQNSQFSMWRDTVLDGFPNQLTESVNHLCLLDTAFFVNSSYPPLLRPERKVDLIIH
LNYCAGSQTKPMKQTCEYCTVQNIPFPKYELQEDEDSLKECYLMENPREPDAPIVLFFPL
INDTFQKYKAPGVERSPEELEQGHVDIYGPKTPYATKELTYTEAAFDKLVKLSEYNILNN
KDKLLQALRLAVEKKRLKSQCPS
NT seq
2592 nt
NT seq
+upstream
nt +downstream
nt
atgactctccagagctcggaaggctgtcctggcctgggaactgacgtgttcatcccccag
agcctgcaagaggctgaagaagacagcaggtcagaaagaaatgtcagtgagttcgagctg
ccacgggacccagaacctcctaatctcccacctctgcttcccatggccccttggggctct
gagggcgggctgtctccatgccacctgctgaccgtgaaggtcatccggatgaaaaacgtc
cgacaggctgatagggtgagccagacagactgctttgtgagcctctggctgcccaccgct
tctcatgagaggttgaggactaggaccatctccaactgtccgaacccagagtggaatgaa
accttcagcttccagatccagagccaagtgaagaacgtgctagagctgagcgtctgtgat
gaagacacactgaccccagatgaccatctcttgacaatcctctatgacctcaccaaactc
tgcttccggaagaaaacccacgtgaagttcccactcaacccagagggcatggaagagctg
gaggtggagttcctgctggaggagagtccctctccacccgagagcctcatcaccaatggc
gtgctggtgtctcggcaagtttcctgcctggaggttcatgcagaatgcaggaggcggagg
aagagcaggaaaatgaaggacctcctggtgacagtgaaggagtccttcgagcacacccaa
cgcgtctcgtgctgccaggagccctgccccccaaacccagcctgcttccactaccccaag
tacttccagccctgcatgcacgtggacgtgcccaagagccagtgcagccgtgggctttgc
tgctgctgtgcacacaggaagaacagccctgtccgccagccccttgactgcctccccgat
ggccagaccgtcaccctgccggtgggcgagaactgtgaattacacatgaagtctacaccc
tgccctcagacgctggacgtgcggctgggcttcagcctgtgcccggcagagcaggagttc
ctgcagaagcggaagccggtggtggcgcaggcgctgcaggaggtgttgcagctggaggcc
gacctgcctgtggacgaggtgccgctgatagccatcatggcgacagggggcggaacgaga
tccatgaccgccatgtacggccacctgctggggctgcagaagctgaacctcctgaactgc
gccagctacatcactggcctgtccggggccacctggaccatggcgaccttataccgtgac
cccgactggtcctccaaaaacctggagcccgccatatttgaggcacggaggcatgtggtc
aaggacaagatgcctgccctgttcccagaccagctgtccaaattccaggaggagcttcgg
cagcgcagccaggaaggctacaaggtcacctttacagatttctggggcctgctgattgag
gcctgtctgggggatgagagaaatgaatccaaactgtcagatcagcgtgctgctttgtgc
cagggccagaaccccctgcccgtctacctcaccatcaatgtcaaggatgatgtaagcaac
caggatttcagagagtggtgcgagttctccccctacgaggtgggcctgcagaagtacggg
gccttcatccccaccgagctcttcggctccgagttcttcatggggcggctgatgaagagg
atcccagagtcgcgaatgtgctacatgctaggcttgtggagcagtatcttctcactaaac
ttgcttgatgcctggaatctgtcccaaagctcggaggagtttttccacaggtggacaagg
gagagagtgcatgatatcgaagatgagcccctcctgcctgaaatccccaaatgtgatgcc
aacgtcttggacactgcggtggtgatcccggggtcgtggctgtccaacactttccgcagc
atcctcacgcaccgggccttcgtgtcccagtttcacaacttcctgttggggctgcagctg
cacaccgactacctccagaacagccagttctccatgtggagagacacggtgctagatggt
ttcccgaaccagctgacagagtccgtgaaccacttgtgcctgttggacactgcgttcttc
gtcaactccagctacccgcccctccttaggcccgagagaaaagtcgacctcatcattcac
ctcaattactgcgctgggtcccagacaaagccaatgaaacaaacatgcgagtactgcacc
gtgcagaacatccccttccccaaatacgagctgcaagaggacgaggacagcctcaaggag
tgctacttgatggagaacccccgggagcctgatgcccccatcgtgcttttcttcccactc
atcaacgacactttccagaagtacaaggccccaggtgtggagcgaagccccgaggagctg
gaacagggccacgtggacatttatggccccaaaactccatacgctaccaaggagctgaca
tacacagaggctgcctttgacaagctggtgaagctctctgagtacaacatcctgaataac
aaggacaagctccttcaggccttgagactggcggtggagaagaaacgtctgaagagccag
tgtccctcctaa
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