KEGG   Ursus arctos (brown bear): 113242145
Entry
113242145         CDS       T05909                                 
Symbol
ATP7A
Name
(RefSeq) copper-transporting ATPase 1 isoform X1
  KO
K17686  P-type Cu+ transporter [EC:7.2.2.8]
Organism
uah  Ursus arctos (brown bear)
Pathway
uah01524  Platinum drug resistance
uah04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:uah00001]
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    113242145 (ATP7A)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    113242145 (ATP7A)
Enzymes [BR:uah01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.8  P-type Cu+ transporter
     113242145 (ATP7A)
SSDB
Motif
Pfam: HMA E1-E2_ATPase Hydrolase HMA_PCA1 Hydrolase_3 Hydrolase_6 HAD_2
Other DBs
NCBI-GeneID: 113242145
NCBI-ProteinID: XP_026335907
LinkDB
Position
X
AA seq 1499 aa
MDRRMGVDSVTITVEGMTCNSCVWTIEQRIGKLNGVHHIKVSLEEKNATIIYDPKLQTPK
TLLEAIEDMGFDAILHNPNPFPVLTDTVFLTVAASLAVPWDHIQNTLLKTKGVTDIKISP
QQRTVVVTVIPSIVNANQIIELLPDLSLDTGTLEKKSGTCEEYSMAQAGEVMLKMKVEGM
TCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLITAEEIKRQIEAVGFPAFIKK
QPKYLKLGAIDIERLKNTPVKSSEGSQQRSPSYTSDSTVTFVIDGMHCKSCVLNIESALS
TLQYVSSIVVSLENRSAIVKYNANSVTPETLRKAIEAVSPGQYRVSISSEAESTSNSPSS
SSLQKIPLNIASHPLTQETVINIYGMTCNSCVQSIEGVISKKAGVKSIRVSLANGNGTVE
YDPLLTTPETLREAIEDMGFDAALSDTNEPLVIIAQTSSEMPLLTSTNEFYTKMMTPIHD
VEAKTSSKCYIQVTGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPPV
IAEFIRELGFGATMIENADEGDGVLELVVRGMTCASCVHKIESILTKHRGIFYCSVALAT
NKAHIKYDPEIIGPRDIIHMVESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFC
IPVMGLMIYMMVMDHHLAALHHNKNMSQEEMTNIHSSMFLERQILPGLSIMNLLSFLLCV
PVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKVNPITFF
DTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVEL
VQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKSGSTVIAGSINQNGSLL
IRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVIISITTLLVWIIIGF
LNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQ
NGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVESNRISRSKILAIVGTAE
SNSEHPLGAAITKYCKQELDTETLGTCVDFQVVPGCGISCKVINIEGLLHKNNWKIEENN
IKNASLVQIGASNEQSSTSSSMIIDAQLSNALNAQQYKVLIGNREWMIRNGLVVNNDVDD
SMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTA
RSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGTG
TDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIG
LVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYENYELHARSQMGQKRPSEISVHVGID
DTSRNSPKLGLLDRFVNYSRASINSLLSDKRSLNSIGTGEPDKHSLLVGDCREDDDTTL
NT seq 4500 nt   +upstreamnt  +downstreamnt
atggatcgacgtatgggtgtggattcggtcaccatcactgttgaggggatgacatgtaat
tcctgtgtttggaccattgagcagcggattggaaaactgaatggtgtacatcatattaaa
gtttcactggaagaaaaaaatgcaactattatttatgaccctaaactacagactccaaag
accctactggaagctattgaggacatgggctttgatgctattctccacaatcctaatcct
ttccctgttttaactgatactgtgtttctgactgttgctgcttcactggctgtgccatgg
gaccatatccaaaacacattgctcaagaccaagggtgtgacagacattaaaatttcccct
cagcaaagaactgtagtggtgacagtaattccttctatagtgaatgccaatcagataata
gagctgcttccagatctcagtttagatactggaactctggagaaaaagtcaggaacttgt
gaagaatacagtatggctcaagcaggtgaagtcatgctgaagatgaaagtagaaggcatg
acctgccattcatgcaccagcaccattgaaggaaaaattgggaagctgcaaggtgttcag
cgaattaaagtttccctggacaaccaagaagctactattgtttatcaacctcatcttatc
acagcagaggaaataaaaaggcagattgaagctgtgggctttccagcattcatcaagaaa
cagcccaagtacctcaaattgggagctattgatatagaacgcctaaagaatacaccagtc
aaatcctcagaaggatcacagcaaaggagtccatcatacaccagtgattcaacagtcact
ttcgttatagatggcatgcattgtaaatcatgtgtgttaaacattgaaagtgctttatct
acactccaatatgtaagcagcatagtagtttccttagagaatagatctgccatagtgaag
tacaatgcaaactcagtcactccagaaaccctgagaaaagcgatagaggccgtgtcacca
gggcaatatagagttagtatttcaagtgaagctgagagcacctcaaactctccctccagc
tcatctcttcaaaagattcctttgaacatagctagccatcctctgactcaagaaactgtg
ataaacatttatggaatgacttgtaattcttgtgttcagtctattgagggtgttatatca
aaaaaggcaggtgtaaaatccatacgagtctctcttgcaaatggcaatgggactgttgag
tatgatcctctactaaccactccagaaaccttgagagaagcaatagaagacatgggattt
gatgctgccttgtcagatacaaatgagccattggtaataatagctcagacctcatcggaa
atgccgcttttgacctcaactaatgaattttatactaaaatgatgacaccaattcacgat
gtggaggcaaagacttcatctaagtgttacatacaggtcactggtatgacttgtgcttcc
tgtgtagcaaacattgaacggaatttaagacgagaagaaggaatatattctgtacttgtg
gctctgatggctggcaaggcagaagtaaggtataatcctgctgttatacaacccccagtg
atagctgagttcatccgagagcttggatttggagccactatgatagaaaatgctgatgaa
ggagatggtgttttggaacttgttgtgagaggaatgacgtgtgcctcctgtgtacataaa
atagagtctatcctcacaaaacacagagggatcttctactgctctgtggccctggcaacc
aacaaagcacatattaaatatgacccagaaattattggtcccagggatattatccatatg
gttgaaagcttaggttttgaagcttctttggtcaagaaggatcgatcagcaagccacctg
gaccataaacgagaaataagacagtggagacggtccttccttgtgagcctctttttctgt
attcctgtaatggggctgatgatatatatgatggttatggatcaccatcttgcagctctt
caccataataagaacatgagtcaagaagaaatgaccaacattcattcttccatgttcctg
gagcgccagatcctgccaggattgtccattatgaatttgctatcctttctattgtgtgta
cctgtacagttttttggaggctggtacttctacatccaggcctacaaagccctgaagcat
aaaactgcaaatatggatgtactgattgtgctggcaaccaccattgcatttgcctactct
ttggttattcttctggttgcgatgtatgaaagagccaaagtaaacccaattactttcttt
gacacacctcctatgctatttgtgtttattgcactaggccggtggctggagcatatagca
aagggcaaaacatcagaggctcttgctaagttaatttcactacaagctacggaagcaact
attgtaactcttgactctgataatattctcttaagtgaagaacaagtggatgtggaactc
gtacaacgtggagacatcattaaagtggttccaggaggcaaatttccagtggatggtcgt
gttattgaagggcattctatggtagatgagtcccttatcacaggggaggcaatgcctgtg
gctaagaagtctggcagcacagtaattgctggttccattaaccagaatgggtcgctactt
atccgtgcaacccatgttggagctgacacaacactttctcaaattgttaaacttgtggaa
gaggcacaaacgtcaaaggctcctatccagcagtttgcagacaaactcagtggctacttt
gttccttttattgttattatttccatcactaccctcttggtttggattataattggattt
ctgaattttgaaattgtggaaacctactttcctggatataacagaagtatctcccgaaca
gaaacgataatacgctttgctttccaagcctctatcacagttctgtgcattgcatgcccc
tgttcactgggactagccactccaactgctgtgatggtgggtacaggagtaggcgctcaa
aatggcatactaatcaaaggtggcgagccattggagatggctcataaggtgaaggtagtg
gtatttgataagaccggaaccattacccatggaaccccagtagtgaatcaagtaaaggtt
ctagtggaaagtaacagaatatcacgcagtaagatcctggccatcgtgggaactgctgaa
agtaacagtgaacaccctctaggagcagccataaccaaatactgcaagcaggagctggac
actgaaaccttgggtacctgcgtagatttccaggttgtgccaggctgtggtattagctgt
aaagtcatcaatattgaaggcttgctacataagaataactggaagatagaggaaaataat
attaaaaatgcatccctggttcaaattggtgcgagtaatgaacagtcatcaacttcatct
tccatgattattgatgcccagctctcaaatgctcttaatgctcagcagtacaaagtcctc
attggtaaccgggagtggatgattagaaacggtcttgttgttaataacgatgtagatgat
tccatgaccgaacatgaaagaaaaggtcggactgctgtattggtggcagttgatgatgag
ctgtgtggcttgatagctattgctgatacagtgaagcctgaagcagaattggctgtccat
attttgaaatctatgggcttagaagtagttctgatgactggagacaacagtaaaacggct
agatctattgcttctcaggttggcattacaaaggtgtttgctgaagttctcccttctcat
aaggttgctaaggtgaagcaacttcaggaggaggggaaacgggttgcaatggtaggagat
gggatcaatgactctccagccctggcgatggctaatgtaggaattgccattggcacgggt
acagatgtagccattgaagcagctgatgtggttttgataaggaatgatcttctggatgta
gtggcaagtattgacttatcaaggaagactgtcaagaggattcggataaattttgttttt
gcgctaatttataatctagttggaattcccatagctgctggagtttttatgcctatcggt
ttggttttgcagccctggatgggatctgcggcaatggctgcctcatctgtttcagtagta
ctttcttctctcttccttaagctttatagaaaaccaacttacgagaattacgaactgcat
gcccgaagccagatgggacagaaaaggccttcagagatcagcgttcatgttggaatagat
gacacctcgagaaattctcctaaactgggtttgctggaccggtttgttaattacagcaga
gcctccataaattcactactgtctgataaacggtccctaaacagcattggtactggtgaa
cctgacaagcattcacttctggtgggagactgcagggaagatgatgacaccacattgtaa

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