Ursus arctos (brown bear): 113242413 Help Entry 113242413         CDS       T05909                                  Symbol HIF1A Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism uah  Ursus arctos (brown bear) Pathway uah04066   HIF-1 signaling pathway uah04137   Mitophagy - animal uah04140   Autophagy - animal uah04148   Efferocytosis uah04659   Th17 cell differentiation uah04919   Thyroid hormone signaling pathway uah05167   Kaposi sarcoma-associated herpesvirus infection uah05200   Pathways in cancer uah05205   Proteoglycans in cancer uah05208   Chemical carcinogenesis - reactive oxygen species uah05211   Renal cell carcinoma uah05230   Central carbon metabolism in cancer uah05231   Choline metabolism in cancer uah05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:uah00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     113242413 (HIF1A)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     113242413 (HIF1A)    04137 Mitophagy - animal     113242413 (HIF1A)    04148 Efferocytosis     113242413 (HIF1A)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     113242413 (HIF1A)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     113242413 (HIF1A)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     113242413 (HIF1A)    05205 Proteoglycans in cancer     113242413 (HIF1A)    05208 Chemical carcinogenesis - reactive oxygen species     113242413 (HIF1A)    05230 Central carbon metabolism in cancer     113242413 (HIF1A)    05231 Choline metabolism in cancer     113242413 (HIF1A)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     113242413 (HIF1A)   09162 Cancer: specific types    05211 Renal cell carcinoma     113242413 (HIF1A)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     113242413 (HIF1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:uah03000]     113242413 (HIF1A) Transcription factors [BR:uah03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     113242413 (HIF1A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  113242413 NCBI-ProteinID:  XP_026336222 LinkDB All DBs Position Unknown AA seq 823 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSASTITVFQ PAQIQEPPVTTATTTATTDELKTVTKDGIEDIKILIASPSPIRAPKVTSSATTSPYSDPG SRTASPNRAGEGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKIE HDGSLFQAVGIGTLLQQPDDRAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLL GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN NT seq 2472 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa aagtctagagatgcagctagatctcggcgaagtaaggagtccgaagttttttatgagctt gctcatcagttgccacttccccataacgtgagctcacatcttgataaggcttctgttatg aggcttaccatcagctatttgcgtgtaaggaaacttctggatgctggtgatttagatatt gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccctggatggttttgtt atggttcttacagatgatggtgacatgatttacatttctgataatgtgaacaaatacatg ggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccgtgtgac catgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga actatgaacataaagtcagcaacatggaaagtacttcactgcacaggccatattcatgtc tacgataccaatagtaaccagtcccagtgtgggtataagaaaccacccatgacgtgcttg gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagacagcaag acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact gaattgatgggatatgagccagaagaacttttgggccgctcaatctatgaatattatcat gctttggattctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc accacaggacagtacaggatgcttgccaaaagaggtggatacgtatgggttgaaactcaa gcaactgtcatatataacactaagaactctcagccacagtgcattgtatgtgtaaattat gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagtcgaatca gaagatacaagtagtctttttgataaacttaagaaggaacctgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagattttggcagcaatgacacagaaact gatgaccaacaacttgaggaagttccattgtataatgatgtaatgctcccctcatccaac gaaaaattacagaatataaatttggcaatgtctccattacctgcttctgaaactccaaag ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagagcca aatccagagtcattggaactttcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacagagttcacctgagcctaacagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtggagaaacttttt gctgaagacacagaagcaaagaatccattttctacccaggacactgatttagacttggag atgttagctccttatatcccaatggatgacgacttccagttacgttccttcgatcagttg tcgccactggaaagcagttctacaagccctcaaagtgcgagcacaattacagtattccag ccagctcaaatccaagaacctcctgttaccactgccactaccactgctaccactgatgaa ttaaaaacagtgacaaaagatggtatagaagacattaaaatattgattgcatctccatct cctatccgtgcacctaaagtaactagtagtgccacaacatcaccatacagtgatcctgga agtcggacagcctcaccgaacagagcaggagaaggagtcatagaacagacagaaaaatct catccaagaagccccaacgtgttatctgtcactttgagtcaaagaactaccattcctgag gaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa catgacggttcactttttcaagcagtaggaattggaacgttattacagcagccagacgat cgtgcagctactacatcactttcgtggaaacgcgtaaaaggatgcaaatctagtgaacag aatggaatggagcaaaagacaattattttaataccctctgatttagcgtgtagactgctg gggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaat gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat caagttaactga

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