Ursus arctos (brown bear): 113242563
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Entry
113242563 CDS
T05909
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04010
MAPK signaling pathway
uah04020
Calcium signaling pathway
uah04022
cGMP-PKG signaling pathway
uah04024
cAMP signaling pathway
uah04260
Cardiac muscle contraction
uah04261
Adrenergic signaling in cardiomyocytes
uah04270
Vascular smooth muscle contraction
uah04723
Retrograde endocannabinoid signaling
uah04725
Cholinergic synapse
uah04726
Serotonergic synapse
uah04727
GABAergic synapse
uah04911
Insulin secretion
uah04912
GnRH signaling pathway
uah04921
Oxytocin signaling pathway
uah04924
Renin secretion
uah04925
Aldosterone synthesis and secretion
uah04927
Cortisol synthesis and secretion
uah04929
GnRH secretion
uah04934
Cushing syndrome
uah04935
Growth hormone synthesis, secretion and action
uah05010
Alzheimer disease
uah05020
Prion disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05207
Chemical carcinogenesis - receptor activation
uah05410
Hypertrophic cardiomyopathy
uah05412
Arrhythmogenic right ventricular cardiomyopathy
uah05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113242563 (CACNA1S)
04020 Calcium signaling pathway
113242563 (CACNA1S)
04024 cAMP signaling pathway
113242563 (CACNA1S)
04022 cGMP-PKG signaling pathway
113242563 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
113242563 (CACNA1S)
04929 GnRH secretion
113242563 (CACNA1S)
04912 GnRH signaling pathway
113242563 (CACNA1S)
04921 Oxytocin signaling pathway
113242563 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
113242563 (CACNA1S)
04924 Renin secretion
113242563 (CACNA1S)
04925 Aldosterone synthesis and secretion
113242563 (CACNA1S)
04927 Cortisol synthesis and secretion
113242563 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
113242563 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
113242563 (CACNA1S)
04270 Vascular smooth muscle contraction
113242563 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
113242563 (CACNA1S)
04725 Cholinergic synapse
113242563 (CACNA1S)
04726 Serotonergic synapse
113242563 (CACNA1S)
04723 Retrograde endocannabinoid signaling
113242563 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
113242563 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
113242563 (CACNA1S)
05020 Prion disease
113242563 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
113242563 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
113242563 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
113242563 (CACNA1S)
05414 Dilated cardiomyopathy
113242563 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
113242563 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
uah04040
]
113242563 (CACNA1S)
Ion channels [BR:
uah04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
113242563 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
113242563
NCBI-ProteinID:
XP_044233717
LinkDB
All DBs
Position
Unknown
AA seq
1867 aa
AA seq
DB search
MEPSSPHDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPVRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSKVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGVLELLLVESGAMSPLGISVLRCIRLLRLFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSMMYNGIMAYGGPSYPGVLVCAYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVIAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAVRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDVGPVHNHRVEMAIFFITYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTVCLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKRCEPGSDYAPGEEYTCGTSFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPSTNPLARANTNNANANIAYDNSNHSNSVH
YEREFPGETETPAARGAFGQLRRVLGPHSKSCVEELKGQLTQREISSSQASPAPCQHARA
EPPLPEARRSPTPGALPEEASHSSRTKESGSLCQTPATAQLIQEALVRGGLDTLAADANF
VMVTGQALADACQMAPEEVEVAATELLKRQESPEGLASALGRWSLRSSLGSLDQHQGSRE
TLIPPRP
NT seq
5604 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccacgatgagggcctgaggaagaaacaacccaagaagcccgtt
cctgagattctgccaaggcccccccgggccctgttctgcttgaccctccagaaccccgtg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagaccatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccggaagacgacaacaac
actctgaaccttggcctggagaaactggagtatttcttcctcattgttttctcgattgaa
gccgccatgaagatcattgcctacggcttcctattccaccaggatgcctatctgcgcagc
ggctggaatgtgctagacttcatcattgtcttcctgggggttttcaccgtgattctggaa
caggttaatgtcatccaaagcaacacagccccgatgagcagcaaaggggctggtctggac
gtcaaggccctgagagccttccgcgtgctcagacccctccggctggtgtcaggggtgccg
agcctgcaggtggtcctcaattccatcttcaaggccatgctgcccctgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcataagacctgctacttcattgggacagatatcgtggccaccgtggagaacgag
aagccctcgccctgcgccaggacgggctctgggcgtccatgcaccatcaatggcagcgag
tgtcggggtggctggccggggcccaaccatggcatcacccactttgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggcgaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggag
gaggacctccgaggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctttggatgagggaggctccgacacagaaagcctgtatgaa
atcgagggcctgaacaaaatcatccagttcgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccatgatgtgatcaagtccaaagtcttctattggctggtgatcctg
gtcgtggccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctgtggctg
acccacttgcaagacgtggccaaccgggtgctgctggcgctcttcaccatcgagatgctg
atgaagatgtacgggctggggctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcgtgctggagctcctgctcgtggagtcgggcgccatgagc
ccactgggcatctccgtgctgcgctgcatccgcctccttaggctcttcaagatcaccaag
tactggacgtctctgagcaacctggtggcgtccctgctcaactccatccgctctatcgcc
tccctgctgctgctgctcttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtatgacttcgaggacacggaggtgcgacgcagcaacttcgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctgacaggggaagactggaactccatgatg
tacaacgggatcatggcctacggcgggccgtcctaccccggggtgctcgtgtgtgcttat
ttcatcatccttttcgtctgtggcaactatatcctgctcaacgtcttcctggccatcgcc
gtggacaacctggccgaagcagagagcctgacctctgcccagaaggccaaggcggaagag
aagaagcgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaagtcagtt
atagccaagaagctggaacagaaacccaagggtgagggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtaaaggatccctacccctcggctgac
ttcccaggcgatgatgaagaagacgagcctgagatccccgtgagcccccggccacgcccc
ctggccgagctgcagctgaaagagaaggcagtacccattccagaagccagctccttcttc
atcttcagccccaccaacaagatccgtgtcctgtgtcatcgcattgtcaacgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagcgccgcgctggctgccgaggac
cccatccgggccgagtctgtgaggaatcagatccttgggtattttgacatcgcgttcacc
tctgtcttcaccgtggagatcgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctggtggtggtggccgtgtccctt
atctccatgggacttgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccgacccctccgggccatcaacagagccaaagggctgaagcatgtggtgcaatgc
gtgtttgtggctgtccgcacaatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acgcagatggagctgcgtccgcgccagtggatacacagtgatttccactttgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacttttgagggatggcctcagctactc
taccaggccatcgactcgtacaaggaggacgtgggccccgtccacaaccaccgcgtggag
atggccatcttcttcatcacctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggctttgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgag
ctgaacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccgcccactgaggtgc
tatatccccaaaaacccgtaccagtaccaggtgtggtatgtggtcacctcgtcctacttc
gagtacctgatgttcgccctcatcatgctcaacaccgtctgcctgggcatgcagcactac
aaccagtccgaggagatgaaccacatctcagacatcctcaatgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggac
ccctggaacgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagt
gaaatcgacacattcctggcctccagcggaggactgtattgcctgggtggaggctgcggg
aacgttgaccccgacgagagtgcccgcatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcggagggagtacgcacgctcctgtggaccttc
atcaagtccttccaggccctgccgtatgtggccctgctcatcgtcatgctcttcttcatc
tacgccgtcatcggcatgcagatgttcggtaagatcgccatggtggacgggacccaaata
aaccgcaacaacaacttccagaccttcccacaggcggtgctgctgctcttcaggtgcgcg
acaggtgaggcatggcaggagatcctcctggcctgcagctacggcaagcggtgtgagccc
gggtccgactacgccccgggggaggagtacacgtgcggcaccagcttcgcctactactac
ttcatcagcttctacatgctctgcgccttcctgatcattaacctctttgtagctgtcatc
atggacaactttgactacctcacgcgggactggtccatcctgggccctcatcatctggat
gagttcaaggccatttgggcagagtatgacccggaggctaagggcagaatcaaacacttg
gatgtggtgaccctgctgagacggatccagccccctctgggctttgggaagttctgcccc
caccgggtggcatgtaagcgcctggtgggcatgaacatgcccttgaacagcgatggcacg
gtcaccttcaacgccactctcttcgccctggtccgtacggcactcaagatcaagacagaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaattggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgtcag
gaagagtattatgggtatcggcccaagaaggacaccatacagatccaggccggattgcgg
accattgaggaagaggcagccccagagatccgccgcaccatctcaggagacctgacagct
gaagaggagctggagagagccatggtagaggctgcgatggaggaagggatattccggagg
actggaggcctctttggccaggtggacaacttcctggaaaggaccaactccctgccccct
gtcatggccaaccagagaccgctccagtttgctgagatagagatggaagagctggaatca
cctgtcttcttggaggatttccctcaagatccgagcaccaaccctcttgctcgtgccaat
accaacaatgccaacgccaacattgcctatgacaacagcaaccatagcaacagcgtccac
tatgaaagggagttccctggagagacagagacgcctgctgccagaggagcctttggccaa
ctccgaagggtcctgggaccccacagcaaatcctgtgtggaagagctaaaaggacagctg
acccagagagaaatttccagctcccaggcatctcctgccccctgccagcatgccagggcc
gagcctcccctgcctgaggcgaggaggagccctaccccgggcgctctgcctgaggaagca
tcccacagcagtaggaccaaggagagtggttccctgtgccagactccggcaacagcacag
ctgattcaagaggctctggttcgaggaggcctggacaccttggcggctgacgctaacttt
gtcatggtgaccggccaggccctggcagatgcctgccagatggcaccagaggaagtggag
gtggcagccacagagctgctgaaaagacaagagtccccagagggcctggccagtgccctg
ggacgctggagcctcaggtcctctctgggcagcctggaccagcatcagggctccagggag
accctgatcccgcccaggccgtga
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integrated database retrieval system
