KEGG   Ursus arctos (brown bear): 113242915
Entry
113242915         CDS       T05909                                 
Symbol
MAP2K7
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 7 isoform X1
  KO
K04431  mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
Organism
uah  Ursus arctos (brown bear)
Pathway
uah04010  MAPK signaling pathway
uah04012  ErbB signaling pathway
uah04141  Protein processing in endoplasmic reticulum
uah04380  Osteoclast differentiation
uah04530  Tight junction
uah04620  Toll-like receptor signaling pathway
uah04660  T cell receptor signaling pathway
uah04664  Fc epsilon RI signaling pathway
uah04668  TNF signaling pathway
uah04722  Neurotrophin signaling pathway
uah04912  GnRH signaling pathway
uah04926  Relaxin signaling pathway
uah04936  Alcoholic liver disease
uah05010  Alzheimer disease
uah05016  Huntington disease
uah05022  Pathways of neurodegeneration - multiple diseases
uah05132  Salmonella infection
uah05135  Yersinia infection
uah05161  Hepatitis B
uah05167  Kaposi sarcoma-associated herpesvirus infection
uah05169  Epstein-Barr virus infection
uah05170  Human immunodeficiency virus 1 infection
uah05208  Chemical carcinogenesis - reactive oxygen species
uah05417  Lipid and atherosclerosis
uah05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    113242915 (MAP2K7)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113242915 (MAP2K7)
   04012 ErbB signaling pathway
    113242915 (MAP2K7)
   04668 TNF signaling pathway
    113242915 (MAP2K7)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    113242915 (MAP2K7)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    113242915 (MAP2K7)
   04660 T cell receptor signaling pathway
    113242915 (MAP2K7)
   04664 Fc epsilon RI signaling pathway
    113242915 (MAP2K7)
  09152 Endocrine system
   04912 GnRH signaling pathway
    113242915 (MAP2K7)
   04926 Relaxin signaling pathway
    113242915 (MAP2K7)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    113242915 (MAP2K7)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    113242915 (MAP2K7)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    113242915 (MAP2K7)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    113242915 (MAP2K7)
   05161 Hepatitis B
    113242915 (MAP2K7)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113242915 (MAP2K7)
   05169 Epstein-Barr virus infection
    113242915 (MAP2K7)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113242915 (MAP2K7)
   05135 Yersinia infection
    113242915 (MAP2K7)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113242915 (MAP2K7)
   05016 Huntington disease
    113242915 (MAP2K7)
   05022 Pathways of neurodegeneration - multiple diseases
    113242915 (MAP2K7)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113242915 (MAP2K7)
   05418 Fluid shear stress and atherosclerosis
    113242915 (MAP2K7)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    113242915 (MAP2K7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uah01001]
    113242915 (MAP2K7)
Enzymes [BR:uah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     113242915 (MAP2K7)
Protein kinases [BR:uah01001]
 Serine/threonine kinases: STE group
  STE7 family
   113242915 (MAP2K7)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase APH RIO1
Other DBs
NCBI-GeneID: 113242915
NCBI-ProteinID: XP_026337050
LinkDB
Position
Unknown
AA seq 435 aa
MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPIIVITLSPAPAPSQRAALQ
LPLANDGGSRSPSSESSPQHPTPPARPRNMLGLPSTLYMPRSMESIEIDQKLQEIMKQTG
YLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRIL
MDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRVQGPIPERILGKMTV
AIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYM
APERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLP
GHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKRYEMLEVDVASWFKDVMAKTESP
RTSGVLSQHHLPFFR
NT seq 1308 nt   +upstreamnt  +downstreamnt
atggcggcgtcctccctggagcagaagctgtcccgcctggaagcaaagctgaagcaggag
aaccgcgaggcccggcggaggatcgacctcaacctggatatcagcccccagcggcccagg
cccattattgtgatcactctaagccctgctcctgccccgtcccaacgagcagccctccag
ctccctctggccaatgatgggggcagtcgctcaccgtcctccgagagctccccacagcac
cccacaccccctgcccggccccgaaacatgctggggcttccgtcaaccttgtatatgccc
cgcagcatggagagcattgagattgaccagaagctgcaggagatcatgaagcagacgggc
tacctgaccatcgggggccagcgctaccaggcagaaatcaacgatctggagaacctgggg
gaaatgggcagcggcacgtgcggccaggtgtggaagatgcgcttcaggaagacaggccac
gtcatcgccgtcaagcaaatgcggcgctccgggaataaggaggagaacaagcggatcctc
atggacctggacgtggtactcaagagccatgactgcccctacatcgtgcagtgtttcggc
accttcatcaccaatacggatgtcttcatcgccatggagctcatgggcacgtgtgctgag
aagctcaagaagcgggtgcagggccccatccccgagcggatcctgggcaagatgacggtg
gcgatcgtgaaggctctgtactacctgaaggagaagcacggcgtgatccaccgtgacgtc
aagccctcgaacatcctgctggacgagcggggccagatcaagctctgtgacttcggcatc
agcggccgtctcgtcgattccaaggccaagacacgcagcgccggctgtgccgcctacatg
gccccggagcgcatagatcctccagaccccaccaagccagactacgacatccgggccgac
gtgtggagcctgggcatctccttggtggagctggcgacgggacagtttccctacaagaat
tgcaagacagactttgaggtccttaccaaagtcctgcaggaagagcccccgctcttgccc
ggccacatgggcttctcaggggactttcagtccttcgtcaaagactgccttactaaggat
cacaggaagagaccaaagtataataagctacttgaacacagcttcatcaagcgctacgag
atgctggaggtagacgtggcgtcctggttcaaggacgtcatggcgaagactgagtcaccg
aggactagcggagtcctgagccagcaccacctgcccttcttcaggtag

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