KEGG   Ursus arctos (brown bear): 113243852
Entry
113243852         CDS       T05909                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
uah  Ursus arctos (brown bear)
Pathway
uah01522  Endocrine resistance
uah04010  MAPK signaling pathway
uah04015  Rap1 signaling pathway
uah04068  FoxO signaling pathway
uah04071  Sphingolipid signaling pathway
uah04114  Oocyte meiosis
uah04148  Efferocytosis
uah04218  Cellular senescence
uah04261  Adrenergic signaling in cardiomyocytes
uah04370  VEGF signaling pathway
uah04380  Osteoclast differentiation
uah04517  IgSF CAM signaling
uah04550  Signaling pathways regulating pluripotency of stem cells
uah04611  Platelet activation
uah04613  Neutrophil extracellular trap formation
uah04620  Toll-like receptor signaling pathway
uah04621  NOD-like receptor signaling pathway
uah04622  RIG-I-like receptor signaling pathway
uah04625  C-type lectin receptor signaling pathway
uah04657  IL-17 signaling pathway
uah04658  Th1 and Th2 cell differentiation
uah04659  Th17 cell differentiation
uah04660  T cell receptor signaling pathway
uah04664  Fc epsilon RI signaling pathway
uah04668  TNF signaling pathway
uah04670  Leukocyte transendothelial migration
uah04714  Thermogenesis
uah04722  Neurotrophin signaling pathway
uah04723  Retrograde endocannabinoid signaling
uah04728  Dopaminergic synapse
uah04750  Inflammatory mediator regulation of TRP channels
uah04912  GnRH signaling pathway
uah04914  Progesterone-mediated oocyte maturation
uah04917  Prolactin signaling pathway
uah04926  Relaxin signaling pathway
uah04932  Non-alcoholic fatty liver disease
uah04933  AGE-RAGE signaling pathway in diabetic complications
uah04935  Growth hormone synthesis, secretion and action
uah04936  Alcoholic liver disease
uah05014  Amyotrophic lateral sclerosis
uah05020  Prion disease
uah05022  Pathways of neurodegeneration - multiple diseases
uah05132  Salmonella infection
uah05133  Pertussis
uah05135  Yersinia infection
uah05140  Leishmaniasis
uah05142  Chagas disease
uah05145  Toxoplasmosis
uah05152  Tuberculosis
uah05161  Hepatitis B
uah05163  Human cytomegalovirus infection
uah05167  Kaposi sarcoma-associated herpesvirus infection
uah05169  Epstein-Barr virus infection
uah05170  Human immunodeficiency virus 1 infection
uah05171  Coronavirus disease - COVID-19
uah05205  Proteoglycans in cancer
uah05208  Chemical carcinogenesis - reactive oxygen species
uah05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uah05415  Diabetic cardiomyopathy
uah05417  Lipid and atherosclerosis
uah05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113243852 (MAPK14)
   04015 Rap1 signaling pathway
    113243852 (MAPK14)
   04370 VEGF signaling pathway
    113243852 (MAPK14)
   04668 TNF signaling pathway
    113243852 (MAPK14)
   04068 FoxO signaling pathway
    113243852 (MAPK14)
   04071 Sphingolipid signaling pathway
    113243852 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    113243852 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    113243852 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    113243852 (MAPK14)
   04218 Cellular senescence
    113243852 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    113243852 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113243852 (MAPK14)
   04613 Neutrophil extracellular trap formation
    113243852 (MAPK14)
   04620 Toll-like receptor signaling pathway
    113243852 (MAPK14)
   04621 NOD-like receptor signaling pathway
    113243852 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    113243852 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    113243852 (MAPK14)
   04660 T cell receptor signaling pathway
    113243852 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    113243852 (MAPK14)
   04659 Th17 cell differentiation
    113243852 (MAPK14)
   04657 IL-17 signaling pathway
    113243852 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    113243852 (MAPK14)
   04670 Leukocyte transendothelial migration
    113243852 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    113243852 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    113243852 (MAPK14)
   04917 Prolactin signaling pathway
    113243852 (MAPK14)
   04926 Relaxin signaling pathway
    113243852 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    113243852 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    113243852 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    113243852 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    113243852 (MAPK14)
   04722 Neurotrophin signaling pathway
    113243852 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113243852 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    113243852 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    113243852 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    113243852 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    113243852 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113243852 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    113243852 (MAPK14)
   05161 Hepatitis B
    113243852 (MAPK14)
   05171 Coronavirus disease - COVID-19
    113243852 (MAPK14)
   05163 Human cytomegalovirus infection
    113243852 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113243852 (MAPK14)
   05169 Epstein-Barr virus infection
    113243852 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113243852 (MAPK14)
   05135 Yersinia infection
    113243852 (MAPK14)
   05133 Pertussis
    113243852 (MAPK14)
   05152 Tuberculosis
    113243852 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    113243852 (MAPK14)
   05140 Leishmaniasis
    113243852 (MAPK14)
   05142 Chagas disease
    113243852 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    113243852 (MAPK14)
   05020 Prion disease
    113243852 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    113243852 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113243852 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    113243852 (MAPK14)
   05415 Diabetic cardiomyopathy
    113243852 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    113243852 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    113243852 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    113243852 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    113243852 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uah01001]
    113243852 (MAPK14)
Enzymes [BR:uah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     113243852 (MAPK14)
Protein kinases [BR:uah01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   113243852 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 113243852
NCBI-ProteinID: XP_026338528
LinkDB
Position
Unknown
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaatctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctctccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttcctcatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggcccgacatacagatgatgaaatgaca
ggctatgtggccaccaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcttcagagtctgcaagaaattacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggtgccaatcccttg
gctgtcgacttgctggagaagatgcttgtattggactcagacaagagaattacggcagcc
caagcgctcgcacacgcctactttgctcagtaccacgatcctgatgatgaaccagtggct
gatccttacgatcagtcctttgaaagcagggacctccttatagatgaatggaaaagcctg
acctacgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggaatcc
tga

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