Ursus arctos (brown bear): 113244028
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Entry
113244028 CDS
T05909
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah01522
Endocrine resistance
uah04012
ErbB signaling pathway
uah04066
HIF-1 signaling pathway
uah04140
Autophagy - animal
uah04150
mTOR signaling pathway
uah04151
PI3K-Akt signaling pathway
uah04152
AMPK signaling pathway
uah04211
Longevity regulating pathway
uah04213
Longevity regulating pathway - multiple species
uah04350
TGF-beta signaling pathway
uah04371
Apelin signaling pathway
uah04666
Fc gamma R-mediated phagocytosis
uah04714
Thermogenesis
uah04910
Insulin signaling pathway
uah04931
Insulin resistance
uah05163
Human cytomegalovirus infection
uah05165
Human papillomavirus infection
uah05170
Human immunodeficiency virus 1 infection
uah05200
Pathways in cancer
uah05205
Proteoglycans in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05210
Colorectal cancer
uah05212
Pancreatic cancer
uah05221
Acute myeloid leukemia
uah05224
Breast cancer
uah05225
Hepatocellular carcinoma
uah05226
Gastric cancer
uah05231
Choline metabolism in cancer
uah05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
113244028 (RPS6KB2)
04350 TGF-beta signaling pathway
113244028 (RPS6KB2)
04371 Apelin signaling pathway
113244028 (RPS6KB2)
04066 HIF-1 signaling pathway
113244028 (RPS6KB2)
04151 PI3K-Akt signaling pathway
113244028 (RPS6KB2)
04152 AMPK signaling pathway
113244028 (RPS6KB2)
04150 mTOR signaling pathway
113244028 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113244028 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
113244028 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
113244028 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
113244028 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
113244028 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
113244028 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113244028 (RPS6KB2)
05205 Proteoglycans in cancer
113244028 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
113244028 (RPS6KB2)
05231 Choline metabolism in cancer
113244028 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113244028 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
113244028 (RPS6KB2)
05212 Pancreatic cancer
113244028 (RPS6KB2)
05225 Hepatocellular carcinoma
113244028 (RPS6KB2)
05226 Gastric cancer
113244028 (RPS6KB2)
05221 Acute myeloid leukemia
113244028 (RPS6KB2)
05224 Breast cancer
113244028 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
113244028 (RPS6KB2)
05163 Human cytomegalovirus infection
113244028 (RPS6KB2)
05165 Human papillomavirus infection
113244028 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
113244028 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113244028 (RPS6KB2)
01522 Endocrine resistance
113244028 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113244028 (RPS6KB2)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113244028 (RPS6KB2)
Protein kinases [BR:
uah01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
113244028 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Pkinase_fungal
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
113244028
NCBI-ProteinID:
XP_044234281
LinkDB
All DBs
Position
Unknown
AA seq
447 aa
AA seq
DB search
MELTETSVNQGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNVGKIYAMKVLRKAKIV
RNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFL
EDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSGQGHIKLTDFGLCKESIHEGAVTH
TFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSASPASLGGRGPPFTAENRKKT
MDKIIKGKLILPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHINWDDLL
ARRVDPPFRPSLQSEEDVSQFDTHFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDS
IKEGFSFQPKLRSPRRLNSSPRTPVSPLKFSPFEGFRPSSGPLEPTEPPLPPLLPPPPPP
PSSTAPLPIRPPSGTKKSKRGRGRPGR
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atggagctcactgagaccagtgtgaaccagggccccgagcgcatcgggccccactgcttt
gagctgctgcgtgtgctgggcaaggggggctatggcaaggtgttccaagtgcgaaaggtg
cagggcaccaacgtgggcaaaatatatgccatgaaagtcctgaggaaggccaaaattgtg
cgcaacgccaaggacacagcacacacgcgggctgaacggaacattctagagtcagtgaag
caccccttcattgtggaactggcctatgccttccagactggtggcaaactctacctcatc
ctcgagtgcctcagtggcggtgagctcttcacgcatctggagcgagagggcatcttcctg
gaagacacggcctgtttctacctggcggagatcacgctggccctgggccatctccactcc
caaggcatcatctaccgggacctcaaacctgagaacatcatgctcagcggccagggccac
atcaaactgacagactttggtctgtgcaaggagtcgatccacgagggtgccgtcacccac
actttctgtggcaccattgagtacatggcccctgagattctggtacgcagcggccacaac
cgggcagtggactggtggagcctgggggccctgatgtatgacatgctcactggatcggca
agtccagcctccttgggaggaagggggccacccttcactgcggagaaccgaaagaaaacc
atggacaagatcatcaaagggaagctgattctgcccccctacctcacccctgatgcccgg
gaccttgtcaaaaagtttctgaagcggaatcccagccaacggatcgggggtggccccggg
gatgctgctgatgtgcagaggcaccccttcttccggcatattaattgggatgatctcctg
gctcgccgcgtagacccccctttcaggccctctctgcagtcagaggaggatgtgagccag
tttgacacccacttcacgcggcagacgccggtggacagtccagatgatacggccctcagt
gagagcgcaaaccaggccttcctgggcttcacatacgtggcaccctccgtcctggacagc
atcaaggagggcttctccttccagcccaagctgcgctcccccaggcgcctcaacagcagc
ccccggaccccggtcagccccctgaagttctcgccctttgagggattccggcccagctct
ggcccactggagcccacggagccccctctacctcctctcctgccgccgccaccgccacca
ccgtcgagcactgccccactccccatccgacccccctcagggaccaagaagtctaagagg
ggccgtgggcgcccaggccgctag
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