Ursus arctos (brown bear): 113244126 Help Entry 113244126         CDS       T05909                                  Symbol CAPN1 Name (RefSeq) calpain-1 catalytic subunit   KO K01367   calpain-1 [EC:3.4.22.52] Organism uah  Ursus arctos (brown bear) Pathway uah04141   Protein processing in endoplasmic reticulum uah04210   Apoptosis uah04217   Necroptosis uah04218   Cellular senescence uah04382   Cornified envelope formation uah05010   Alzheimer disease uah05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:uah00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     113244126 (CAPN1)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     113244126 (CAPN1)    04217 Necroptosis     113244126 (CAPN1)    04218 Cellular senescence     113244126 (CAPN1)  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     113244126 (CAPN1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     113244126 (CAPN1)    05022 Pathways of neurodegeneration - multiple diseases     113244126 (CAPN1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uah01002]     113244126 (CAPN1) Enzymes [BR:uah01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.52  calpain-1      113244126 (CAPN1) Peptidases and inhibitors [BR:uah01002]  Cysteine peptidases   Family C2: calpain family    113244126 (CAPN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 CAPN13-like_C_EFh Motif Other DBs NCBI-GeneID:  113244126 NCBI-ProteinID:  XP_026339041 LinkDB All DBs Position Unknown AA seq 715 aa AA seqDB search MAEEIITPVYCTGVSAQVQKQRAKELGLGRHENAIKYMGQDYEQLRAHCLQSGALFRDEA FPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA IASLTLSDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYQGQMVSLIRMRNPWGE VEWTGAWSDGSSEWNSVDPYEREQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS RSIRKWNTMLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDADDDYGGRESGCSF VLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANSSRARSEQFIN LREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTQELDDQIQANLPDEQVLS EEEIDENFKALFRQLAGEDMEISVKELQTILNRIISKHKDLRTKGFSLESCRSMVNLMDR DGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFRLNKKLYELI ITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA NT seq 2148 nt NT seq  +upstreamnt  +downstreamnt atggctgaggagatcatcacccccgtgtactgcacgggggtgtccgcacaagtgcagaag cagcgggccaaggagctgggccttggccgccatgaaaatgccatcaagtacatgggccag gactatgagcagctgcgggctcattgcctgcagagtggggccctcttccgtgatgaggct ttccccccggtgccccagagcctaggctacaaggacctgggccccaactcctccaaaacc tatggcatcaagtggaaacgtcccacggagctgctctcaaacccccagttcattgtggat ggagccacccgcacagacatctgccagggagcactgggggattgttggctcctggctgcc attgcctccctcaccctcagtgacacgcttctgcatcgagtggtaccacacggccaaagc ttccagaatggctatgcaggcatcttccatttccagctgtggcagtttggggaatgggtg gatgtggtcgtggatgacctgctgcccatcaaggacgggaagctggtgtttgtgcactcc gcccaaggcaacgagttctggagtgccctgctcgagaaggcctatgccaaggtgaatggc agctacgaggccctctctgggggcagtacttcagagggcttcgaggacttcacaggcggg gtcaccgagtggtatgagctacgcaaggcacccagcgacctctaccaaatcatcctcaag gccctggagcgggggtccctcctgggctgctccattgacatctccagcgttctggacatg gaggccatcaccttcaagaagctggtgaagggccacgcctactctgtgacaggggccaag caggtgaactaccagggccagatggtgagcctgatccggatgcggaatccctggggcgag gtggagtggacgggagcctggagtgacggctcctcggagtggaacagtgtggacccttac gagcgggagcagctccgggtcaagatggaggatggagagttctggatgtccttccgagac ttcatgcgtgagttcacccgcctggagatctgcaacctgacgcccgacgcgctcaagagc cggtcgatccgcaaatggaacaccatgctctatgaggggacctggcggcgggggagcacc gcgggcggctgccggaactacccagccaccttctgggtcaatccccagttcaagatccgg ctggaggagaccgatgatgcggacgatgactacgggggtcgcgagtcaggctgcagcttc gttctagccctcatgcagaagcaccgtcgccgggagcgccgctttggccgcgacatggag accattggcttcgccgtctacgaggtccctccggagctggtgggccagccggccgtgcac ctgaagcgggacttcttcctggctaactcgtcgcgggcgcgctcggagcagttcatcaac ctgcgtgaggtcagcacgcgcttccgcttgccgcccggggagtacgtggtggtaccctcc actttcgagcccaacaaggagggggacttcgtgctgcgcttcttctccgagaagagcgcc gggacccaggagctggacgaccagatccaggccaatctccccgatgagcaagtgctctca gaagaggagattgacgagaacttcaaggccctcttcaggcagctggccggggaggacatg gagatcagcgttaaggagctgcagaccatcctgaacaggatcatcagcaaacacaaggat ctgcgtaccaagggcttcagcctggagtcgtgccgcagcatggtgaacctcatggaccgg gacggcaacgggaagctgggcctggtggagttcaacatcctgtggaatcgcatccggaat tacctgtccatcttccggaagttcgacttggacaagtcgggcagcatgagtgcctacgag atgcggatggccatcgagtctgcaggcttcaggctcaacaagaagctctatgagctcatc atcacccgctactcggagccggacctggccgtggacttcgacaacttcgtgtgttgcctg gtgcgcctggagaccatgttccggtttttcaaaactctggacacagatctggatggcgtc gtgacctttgacttgtttaagtggttacagctgaccatgtttgcatga

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