Ursus arctos (brown bear): 113244432
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Entry
113244432 CDS
T05909
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2 isoform X1
KO
K20994
Notch 2
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01522
Endocrine resistance
uah04330
Notch signaling pathway
uah04658
Th1 and Th2 cell differentiation
uah04919
Thyroid hormone signaling pathway
uah05165
Human papillomavirus infection
uah05200
Pathways in cancer
uah05206
MicroRNAs in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
113244432 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
113244432 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
113244432 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113244432 (NOTCH2)
05206 MicroRNAs in cancer
113244432 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
113244432 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
113244432 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
113244432 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113244432 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
Ank_2
EGF_2
Ank
Notch
NOD
NODP
Ank_5
Ank_3
Ank_4
EGF_3
EGF_Teneurin
JAG1-like_EGF2
EGF_DL_JAG
Elf-1_N
Motif
Other DBs
NCBI-GeneID:
113244432
NCBI-ProteinID:
XP_048076147
LinkDB
All DBs
Position
Unknown
AA seq
2471 aa
AA seq
DB search
MPALRPAPLWALLALWLCRAAPARALQCRDGYEPCVNEGVCVTYHNGTGYCKCLEGFLGE
YCQHRDPCEKNRCQNGGTCMAQAMLGKATCRCALGFTGDDCQYSTTHPCFVSHPCLNGGT
CHVRSRDDYECTCQVGFTGKLCQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
TDVNECDIPGQCQHGGTCLNLPGSYQCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTG
DFTFECNCLPGFEGITCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCDENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGINCEINFDDCASNPCVHGVCM
DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCLCPEGPHHPSCYSQ
VNECLSSPCIHGNCTGGLSGYKCLCDAGWVGINCEVDRNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCQCVLPYTGKNCQTVLAPCSPN
PCENAAVCKEAPNFESYTCLCAPGWQGQRCTVDIDECVSKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCHPGFIGDKCQTDMNECLSEPCKN
GGTCSDYVNSYTCKCQSGFDGVHCENNIDECTESSCFNGGTCIDGINSFSCLCPVGFTGP
FCLHEINECNSHPCLNEGICVDGLGTYRCTCPLGYTGKNCQTLVNLCSRSPCKNKGTCIQ
EKAESRCLCPSGWAGAYCDVPNVSCEVAAFHRGVSTDHLCQHSGVCINAGNSHHCQCPLG
YTGSYCEEQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
TCVDLVNHFKCSCPPGTRGLLCEENIDDCAGGPRCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRNAFTGRHCETFIDVCPQMPCLNGGTCA
VASNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEQCVHTASGPRCFCPNPQDCESGCAS
SPCQHGGSCYPQRQPPYYSCQCSPPFWGSHCELYTAPTSTPPATCLSQYCADKARDGVCD
EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQGNS
KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQ
DARSFLRALGTLLHTNLHIKRDSQGALMVYPYYGEKSAAMKKQKMTRRSLPGDQEQEVAG
SKVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPKRTQLLY
LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDAIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDGEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
KKPRRPNTKSTMPTSLPNLAKEGKDAKGSRRKKSLSDKGQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
VSQLLSHHHIVPPGSSSAGSLSRLHPVTVPADWMNRMEMNETQYNEMFGMVLAPAEGTHP
GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGNIAQPAGTPQPQSNCPPPVAGPVPTMY
QIPEMARLPSMAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
EPPRSNMQVYA
NT seq
7416 nt
NT seq
+upstream
nt +downstream
nt
atgcccgccctgcgccccgctccgctgtgggcgctgctggcgctctggctgtgccgcgcg
gcccccgcgcgtgcattgcagtgtcgggatggctatgagccctgtgtaaatgaaggagtg
tgtgttacctaccacaatgggacaggatactgcaaatgtctggagggttttttgggagaa
tattgtcaacatcgagacccctgtgagaagaatcgctgccagaatggtgggacgtgtatg
gcccaggccatgttggggaaagccacatgccgatgtgccctggggttcacaggagatgat
tgccagtactcgaccactcacccctgctttgtttctcacccctgcttgaatggaggcacc
tgccacgtgcgtagccgggatgactatgagtgcacctgccaagttggtttcacaggtaag
ctgtgccagtggactgatgcctgcctgtctcatccctgtgcaaatggaagtacctgtacc
actgtggccaaccagttctcctgcaaatgcctcacaggcttcacaggacagaagtgtgag
actgatgtcaatgagtgtgacattccaggacagtgccagcatggtggcacctgcctcaac
ctaccaggttcctatcagtgccagtgcccccagggcttcacaggtcagcactgtgacagc
ccctacgtgccctgtgcaccctccccctgtgtcaatggtggcacctgccggcagactggt
gacttcacgtttgaatgcaactgccttccaggttttgaggggatcacctgtgagcggaat
attgatgactgccctaaccacaagtgtcagaatggaggggtttgtgtggatggggttaat
acttacaactgtcgctgcccccctcagtggacaggacagttttgcacagaggatgtggat
gagtgtctgctgcaacctaatgcttgtcagaatgggggcacctgtaccaaccgcaatggg
ggctatggctgtgtatgtgttaatggctggagtggagatgactgcagtgagaacattgat
gactgtgccttcgcctcctgcactccgggctccacctgcattgaccgtgtggcctccttc
tcttgcatgtgcccagaaggaaaggcaggtctcttatgtcatctggatgatgcatgcatc
agcaatccttgccacaagggggcactgtgtgataccaaccccctgaatgggcagtatatt
tgcacctgcccccaaggctacaaaggggctgactgcacagaagatgtggatgagtgtgcc
atggccaatagcaatccttgtgagcacgcaggaaaatgtgtgaacacagatggtgccttc
cactgtgaatgtctgaagggctatgcagggcctcgttgtgagatggacatcaatgagtgc
cattccgacccctgccagaacgatgcaacctgtctggataagattggaggcttcacgtgt
ctgtgcatgccaggtttcaaaggtgtgcattgtgaattggagataaacgaatgtcagagc
aacccttgtgtgaacaatggtcagtgtgtggataaagtcaatcgcttccagtgtctgtgt
ccgcctggtttcactgggccagtttgccagattgatattgatgactgttccagtactcca
tgtctgaatggggcaaagtgtattgatcacccgaatggctatgaatgccagtgtgccaca
ggattcactggtgtgttgtgtgatgagaacatcgacaactgtgaccctgatccttgccac
cacggccagtgtcaggatgggattgattcctacacctgcatctgcaacccagggtacatg
ggtgccatctgcagtgaccagatagatgagtgttacagcagcccctgcctgaatgacggc
cgctgcatcgacctggtgaatggctaccagtgcaattgccagcccggcacgtcaggtatt
aattgtgaaatcaattttgatgactgtgcaagtaacccttgtgtccatggagtctgtatg
gatggcattaatcgttacagttgtgtctgctcaccaggattcacagggcagagatgtaac
attgacattgatgagtgtgcctccaatccctgtcgcaagggtgcaacgtgcatcaacgat
gtgaatggtttccgctgtctgtgccctgagggtccccatcaccccagctgctactcacag
gtgaacgagtgcctgagcagcccctgcatccatggaaactgtactgggggcctcagtgga
tacaagtgcctctgtgatgcaggctgggttggcatcaactgcgaagtggacagaaatgaa
tgtctttctaacccatgccagaatggaggaacttgtgacaatctggtgaatggatacagg
tgtacttgcaagaagggctttaaaggctataactgtcaggtgaatattgatgaatgtgct
tcaaatccgtgtctgaaccaaggaacctgctttgatgacataagtggctatacttgccag
tgtgtgctgccatacacaggcaagaattgtcagacagtgttggctccctgttccccaaac
ccgtgtgagaatgctgctgtttgcaaagaggcaccaaattttgagagttacacctgcctg
tgtgcccctggctggcaaggtcagcggtgtacagttgacattgatgagtgtgtctccaag
ccctgcatgaaccacggtctctgccataacacccagggcagctatatgtgtgagtgtcct
ccaggcttcagtggtatggactgtgaggaggacatcgatgactgccttgccaatccttgc
cagaatggaggttcctgtgtagatggagtgaatactttctcctgcctgtgccatcctggc
tttattggggataagtgtcagacagacatgaatgagtgtctgagtgaaccctgtaagaat
ggagggacctgctctgactatgtcaacagttacacttgcaagtgccagtcgggatttgat
ggagtccactgtgagaacaacattgacgagtgcactgagagctcctgtttcaatggtggc
acctgtatcgacgggattaactccttctcttgcttgtgccctgtgggcttcactggcccc
ttctgcctccatgagatcaatgaatgcaactctcatccatgcctaaatgaaggaatatgt
gtcgatggcctgggtacttaccgctgcacctgccccttgggctacactgggaaaaactgt
cagaccctggtgaacctctgtagtcggtctccatgtaagaacaaaggtacctgcattcag
gaaaaagcagagtcccggtgcctgtgtccatccggatgggctggtgcttactgtgatgtg
cccaatgtatcctgtgaggtggcggccttccacagaggggtgtccactgaccacctgtgc
cagcactccggcgtctgcatcaatgctggcaactcacatcactgccagtgccccctgggc
tacactgggagctactgtgaggagcagcttgatgagtgctcatccaatccctgccagcac
ggagccacctgcagggacttcatcggcgggtacagatgtgagtgtgtcccaggctatcag
ggcgtcaattgcgagtatgaagtagatgagtgccagaatcagccatgccagaacgggggc
acctgtgtcgaccttgtgaaccacttcaaatgctcctgtccaccaggcactcgaggcctg
ctttgtgaagagaacatcgatgactgtgccgggggcccccgctgccttaacggtggtcag
tgtgtggataggatcgggggctacagctgtcgctgcttgcctggctttgccggagagcgg
tgtgaaggggacatcaacgagtgcctctcgaacccctgcagctctgagggcagcctggac
tgcatccagctaaccaacgactacctgtgtgtctgccgcaacgccttcactggtcgtcac
tgtgaaactttcattgatgtgtgtccccagatgccttgcctgaatggggggacttgtgct
gtggccagcaacatgcctgatggtttcatttgtcgttgtcccccgggattctccggggca
agatgccagagcagctgtggacaagtgaagtgcaggagaggggagcagtgtgtgcacacg
gcctcgggacctcgctgcttctgtcccaacccccaggactgcgaatcaggctgtgccagt
agcccctgccagcatgggggtagctgctatcctcaacgccagcctccttactactcttgc
cagtgttctccaccattctggggcagccactgtgaactttacacggcccccaccagcact
cctcctgccacgtgcctgagccagtactgtgccgacaaagctcgggatggtgtctgtgat
gaggcctgcaatagccatgcctgccagtgggatgggggtgactgttccctgaccatggaa
aacccctgggccaactgctcttccccacttccctgctgggattacatcaacaaccagtgc
gatgagctgtgcaacacagctgagtgcctttttgacaattttgagtgccaggggaacagc
aagacgtgcaagtatgacaaatactgtgcagaccacttcaaagacaaccattgtgaccag
ggatgcaacagtgaggagtgtggctgggacgggctggactgtgctgctgaccggccagag
aacctggcagaggggaccctggttatagtggtgctcatgcccccggagcagctgctccag
gacgcccgcagcttcctgcgggcgctgggcaccctgctccataccaacctgcacattaaa
cgggactcgcagggggcactcatggtctacccctattatggtgagaagtcagctgccatg
aagaagcagaagatgactcgcaggtcccttcctggtgatcaagagcaggaggtggctggc
tctaaggtatttctggaaattgacaaccgccagtgtgttcaagattcagaccagtgtttc
aagaacacagatgcagcggcagctcttctggcttctcatgccatccaggggaccttgtcc
taccctcttgtgtctgtcgtcagtgaatctctgactccaaaacgcactcagcttctctat
ctacttgctgtggctgtcgtcattatcctgtttattatcctgctgggagttatcatggcg
aaacgaaagcgcaagcatggctccctctggctgcctgaaggtttcacccttcgccgagac
tccagcaatcacaagcgtcgtgagccagtgggacaggatgccgtggggctgaaaaatctc
tcagtgcaagtctcagaagctaacctaattggttctggaacaagtgaacattgggttgat
gatgaagggccccagccaaagaaagccaaggctgaagatgaggctttactctcagaggaa
gatgatgccattgatcgacgtccatggacacagcagcaccttgaggctgcagatatccgc
aggacaccatcgctggcgctcactcctccacaggcggagcaggaggtagacgtgctggac
gtgaatgtccgtggcccagatgggtgcaccccactgatgctggcttctctccgaggaggc
agctcagatatgagcgatgaagatgaagatggagaggactcttcggccaacatcatcaca
gacttggtctaccagggtgccagcctgcaggcccagacagaccggacaggtgaaatggca
ctgcaccttgcggcccgctactcgagggctgatgctgccaagcgtctcctggatgcaggt
gcggacgccaacgcgcaggacaacatgggccgctgccctctccatgctgcagtggcagct
gacgcccagggggtcttccagattctgatccgcaaccgagtaactgatctggatgccagg
atgaacgatggcactacaccgctgatcctggccgcccgcctagctgtggagggaatggtg
gcagaactgatcaactgccaagcagatgtgaacgcagtggatgaccatgggaaatctgct
cttcactgggcagctgctgtcaataacgtggaggcaacccttttgctgttgaaaaacggg
gccaaccgagacatgcaggacaacaaggaagagacacctctgtttcttgctgcccgggag
ggaagctatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagac
cacatggatcgtcttccccgggatgtggctcgagaccgcatgcaccatgacattgtgcgc
ctcctggatgagtacaatgtgacaccaagccctccaggcactgtgctgacttctgccctc
tcacctgtgatctgtgggcccaacagatctttcctcagcctaaagcataccccaatgggc
aagaagcctagacggcccaataccaagagtaccatgcccactagcctccctaaccttgcc
aaggagggcaaggatgccaagggtagtaggaggaaaaagtctctgagtgacaagggtcag
ctgtctgagagctcagtgactttatcccccgttgattccttagaatctcctcacacatat
gtttctgacaccacatcctctccaatgattacatcccctggaatcttacaggcctcgccc
aaccctatgttggccactgctgccccccctgccccagtccatgcccagcatgcactgtct
ttctctaacctgcatgaaatgcagcctttggctcatggggccagcactgtgcttccctca
gtgagccagctgctgtcccaccaccacattgtccccccaggcagtagcagtgcgggaagc
ttgagtaggctccatcctgtcactgttccggcagattggatgaaccgcatggagatgaat
gagacccagtacaatgagatgtttggtatggttctggctccagctgagggcacgcaccct
ggcatagctccccagagcaggccacctgaagggaagcacataactacccctcgggagcct
ttgccccccattgtgactttccagctaatccccaaaggcaatattgcccaaccggctggg
actccccagcctcagtccaactgccctcctcctgttgcaggccctgtgcccaccatgtac
cagattccagaaatggctcgtttgcccagtatggctttccccactgccatgatgccccag
caggatgggcaggttgctcagaccattctccctgcctatcatccttttccagcctctgtg
ggcaagtaccctacaccaccttcacagcatagttatgcttcctcaaatgctgctgagcga
acacccagtcacagtggtcacctgcagggtgaacatccctacctgacaccatccccagag
tctcctgaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgacc
accagccctacccctgggggtgctggaggaggtcagcggggacctggaacacacatgtct
gagccaccacgcagcaacatgcaggtttatgcatga
DBGET
integrated database retrieval system
