Ursus arctos horribilis (North American brown bear): 113244432
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Entry
113244432 CDS
T05909
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2
KO
K20994
Notch 2
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah01522
Endocrine resistance
uah04330
Notch signaling pathway
uah04658
Th1 and Th2 cell differentiation
uah04919
Thyroid hormone signaling pathway
uah05165
Human papillomavirus infection
uah05200
Pathways in cancer
uah05206
MicroRNAs in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
113244432 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
113244432 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
113244432 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113244432 (NOTCH2)
05206 MicroRNAs in cancer
113244432 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
113244432 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
113244432 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
113244432 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113244432 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
Ank_2
Ank
Notch
NOD
EGF_2
NODP
Ank_5
Ank_3
Ank_4
EGF_3
JAG1-like_EGF2
DL-JAG_EGF-like
Elf-1_N
Motif
Other DBs
NCBI-GeneID:
113244432
NCBI-ProteinID:
XP_026339553
LinkDB
All DBs
Position
Unknown
AA seq
2245 aa
AA seq
DB search
MFCRRADHLLLHENSLFSLVLPYPGFEGITCERNIDDCPNHKCQNGGVCVDGVNTYNCRC
PPQWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFAS
CTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQG
YKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQ
NDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTG
PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCDENIDNCDPDPCHHGQCQD
GIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGINCEINF
DDCASNPCVHGVCMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRC
LCPEGPHHPSCYSQVNECLSSPCIHGNCTGGLSGYKCLCDAGWVGINCEVDRNECLSNPC
QNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCQCVLPYT
GKNCQTVLAPCSPNPCENAAVCKEAPNFESYTCLCAPGWQGQRCTVDIDECVSKPCMNHG
LCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCHPGFIGDKC
QTDMNECLSEPCKNGGTCSDYVNSYTCKCQSGFDGVHCENNIDECTESSCFNGGTCIDGI
NSFSCLCPVGFTGPFCLHEINECNSHPCLNEGICVDGLGTYRCTCPLGYTGKNCQTLVNL
CSRSPCKNKGTCIQEKAESRCLCPSGWAGAYCDVPNVSCEVAAFHRGVSTDHLCQHSGVC
INAGNSHHCQCPLGYTGSYCEEQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEY
EVDECQNQPCQNGGTCVDLVNHFKCSCPPGTRGLLCEENIDDCAGGPRCLNGGQCVDRIG
GYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRNAFTGRHCETFID
VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRRGEQCVHTASGPRC
FCPNPQDCESGCASSPCQHGGSCYPQRQPPYYSCQCSPPFWGSHCELYTAPTSTPPATCL
SQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNT
AECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADRPENLAEGT
LVIVVLMPPEQLLQDARSFLRALGTLLHTNLHIKRDSQGALMVYPYYGEKSAAMKKQKMT
RRSLPGDQEQEVAGSKVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSV
VSESLTPKRTQLLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKR
REPVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDEGPQPKKAKAEDEALLSEEDDAIDR
RPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSD
EDEDGEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQ
DNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINC
QADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAA
KILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICG
PNRSFLSLKHTPMGKKPRRPNTKSTMPTSLPNLAKEGKDAKGSRRKKSLSDKGQLSESSV
TLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHE
MQPLAHGASTVLPSVSQLLSHHHIVPPGSSSAGSLSRLHPVTVPADWMNRMEMNETQYNE
MFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGNIAQPAGTPQPQS
NCPPPVAGPVPTMYQIPEMARLPSMAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTP
PSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPG
GAGGGQRGPGTHMSEPPRSNMQVYA
NT seq
6738 nt
NT seq
+upstream
nt +downstream
nt
atgttctgtagaagagctgaccacttacttctgcatgagaattcattattttctcttgtt
cttccctatccaggttttgaggggatcacctgtgagcggaatattgatgactgccctaac
cacaagtgtcagaatggaggggtttgtgtggatggggttaatacttacaactgtcgctgc
ccccctcagtggacaggacagttttgcacagaggatgtggatgagtgtctgctgcaacct
aatgcttgtcagaatgggggcacctgtaccaaccgcaatgggggctatggctgtgtatgt
gttaatggctggagtggagatgactgcagtgagaacattgatgactgtgccttcgcctcc
tgcactccgggctccacctgcattgaccgtgtggcctccttctcttgcatgtgcccagaa
ggaaaggcaggtctcttatgtcatctggatgatgcatgcatcagcaatccttgccacaag
ggggcactgtgtgataccaaccccctgaatgggcagtatatttgcacctgcccccaaggc
tacaaaggggctgactgcacagaagatgtggatgagtgtgccatggccaatagcaatcct
tgtgagcacgcaggaaaatgtgtgaacacagatggtgccttccactgtgaatgtctgaag
ggctatgcagggcctcgttgtgagatggacatcaatgagtgccattccgacccctgccag
aacgatgcaacctgtctggataagattggaggcttcacgtgtctgtgcatgccaggtttc
aaaggtgtgcattgtgaattggagataaacgaatgtcagagcaacccttgtgtgaacaat
ggtcagtgtgtggataaagtcaatcgcttccagtgtctgtgtccgcctggtttcactggg
ccagtttgccagattgatattgatgactgttccagtactccatgtctgaatggggcaaag
tgtattgatcacccgaatggctatgaatgccagtgtgccacaggattcactggtgtgttg
tgtgatgagaacatcgacaactgtgaccctgatccttgccaccacggccagtgtcaggat
gggattgattcctacacctgcatctgcaacccagggtacatgggtgccatctgcagtgac
cagatagatgagtgttacagcagcccctgcctgaatgacggccgctgcatcgacctggtg
aatggctaccagtgcaattgccagcccggcacgtcaggtattaattgtgaaatcaatttt
gatgactgtgcaagtaacccttgtgtccatggagtctgtatggatggcattaatcgttac
agttgtgtctgctcaccaggattcacagggcagagatgtaacattgacattgatgagtgt
gcctccaatccctgtcgcaagggtgcaacgtgcatcaacgatgtgaatggtttccgctgt
ctgtgccctgagggtccccatcaccccagctgctactcacaggtgaacgagtgcctgagc
agcccctgcatccatggaaactgtactgggggcctcagtggatacaagtgcctctgtgat
gcaggctgggttggcatcaactgcgaagtggacagaaatgaatgtctttctaacccatgc
cagaatggaggaacttgtgacaatctggtgaatggatacaggtgtacttgcaagaagggc
tttaaaggctataactgtcaggtgaatattgatgaatgtgcttcaaatccgtgtctgaac
caaggaacctgctttgatgacataagtggctatacttgccagtgtgtgctgccatacaca
ggcaagaattgtcagacagtgttggctccctgttccccaaacccgtgtgagaatgctgct
gtttgcaaagaggcaccaaattttgagagttacacctgcctgtgtgcccctggctggcaa
ggtcagcggtgtacagttgacattgatgagtgtgtctccaagccctgcatgaaccacggt
ctctgccataacacccagggcagctatatgtgtgagtgtcctccaggcttcagtggtatg
gactgtgaggaggacatcgatgactgccttgccaatccttgccagaatggaggttcctgt
gtagatggagtgaatactttctcctgcctgtgccatcctggctttattggggataagtgt
cagacagacatgaatgagtgtctgagtgaaccctgtaagaatggagggacctgctctgac
tatgtcaacagttacacttgcaagtgccagtcgggatttgatggagtccactgtgagaac
aacattgacgagtgcactgagagctcctgtttcaatggtggcacctgtatcgacgggatt
aactccttctcttgcttgtgccctgtgggcttcactggccccttctgcctccatgagatc
aatgaatgcaactctcatccatgcctaaatgaaggaatatgtgtcgatggcctgggtact
taccgctgcacctgccccttgggctacactgggaaaaactgtcagaccctggtgaacctc
tgtagtcggtctccatgtaagaacaaaggtacctgcattcaggaaaaagcagagtcccgg
tgcctgtgtccatccggatgggctggtgcttactgtgatgtgcccaatgtatcctgtgag
gtggcagccttccacagaggggtgtccactgaccacctgtgccagcactccggcgtctgc
atcaatgctggcaactcacatcactgccagtgccccctgggctacactgggagctactgt
gaggagcagcttgatgagtgctcatccaatccctgccagcacggagccacctgcagggac
ttcatcggcgggtacagatgtgagtgtgtcccaggctatcagggcgtcaattgcgagtat
gaagtagatgagtgccagaatcagccatgccagaacgggggcacctgtgtcgaccttgtg
aaccacttcaaatgctcctgtccaccaggcactcgaggcctgctttgtgaagagaacatc
gatgactgtgccgggggcccccgctgccttaacggtggtcagtgtgtggataggatcggg
ggctacagctgtcgctgcttgcctggctttgccggagagcggtgtgaaggggacatcaac
gagtgcctctcgaacccctgcagctctgagggcagcctggactgcatccagctaaccaac
gactacctgtgtgtctgccgcaacgccttcactggtcgtcactgtgaaactttcattgat
gtgtgtccccagatgccttgcctgaatggggggacttgtgctgtggccagcaacatgcct
gatggtttcatttgtcgttgtcccccgggattctccggggcaagatgccagagcagctgt
ggacaagtgaagtgcaggagaggggagcagtgtgtgcacacggcctcgggacctcgctgc
ttctgtcccaacccccaggactgcgaatcaggctgtgccagtagcccctgccagcatggg
ggtagctgctatcctcaacgccagcctccttactactcttgccagtgttctccaccattc
tggggcagccactgtgaactttacacggcccccaccagcacccctcctgccacgtgcctg
agccagtactgtgccgacaaagctcgggatggcgtctgcgatgaggcctgcaatagccat
gcctgccagtgggatgggggtgactgttccctgaccatggaaaacccctgggccaactgc
tcttccccacttccctgctgggattacatcaacaaccagtgcgatgagctgtgcaacaca
gctgagtgcctttttgacaattttgagtgccaggggaacagcaagacgtgcaagtatgac
aaatactgtgcagaccacttcaaagacaaccattgtgaccagggatgcaacagtgaggag
tgtggctgggacgggctggactgtgctgctgaccggccagagaacctggcagaggggacc
ctggttatagtggtgctcatgcccccggagcagctgctccaggacgcccgcagcttcctg
cgggcgctgggcaccctgctccataccaacctgcacattaaacgggactcgcagggggca
ctcatggtctacccctattatggtgagaagtcagctgccatgaagaagcagaagatgact
cgcaggtcccttcctggtgatcaagagcaggaggtggctggctctaaggtatttctggaa
attgacaaccgccagtgtgttcaagattcagaccagtgtttcaagaacacagatgcagcg
gcagctcttctggcttctcatgccatccaggggaccttgtcctaccctcttgtgtctgtc
gtcagtgaatctctgactccaaaacgcactcagcttctctatctacttgctgtggctgtc
gtcattatcctgtttattatcctgctgggagttatcatggcgaaacgaaagcgcaagcat
ggctccctctggctgcctgaaggtttcacccttcgccgagactccagcaatcacaagcgt
cgtgagccagtgggacaggatgccgtggggctgaaaaatctctcagtgcaagtctcagaa
gctaacctaattggttctggaacaagtgaacattgggttgatgatgaagggccccagcca
aagaaagccaaggctgaagatgaggctttactctcagaggaagatgatgccattgatcga
cgtccatggacacagcagcaccttgaggctgcagatatccgcaggacaccatcgctggcg
ctcactcctccacaggcggagcaggaggtagacgtgctggacgtgaatgtccgtggccca
gatgggtgcaccccactgatgctggcttctctccgaggaggcagctcagatatgagcgat
gaagatgaagatggagaggactcttcggccaacatcatcacagacttggtctaccagggt
gccagcctgcaggcccagacagaccggacaggtgaaatggcactgcaccttgcggcccgc
tactcgagggctgatgctgccaagcgtctcctggatgcaggtgcggacgccaacgcgcag
gacaacatgggccgctgccctctccatgctgcagtggcagctgacgcccagggggtcttc
cagattctgatccgcaaccgagtaactgatctggatgccaggatgaacgatggcactaca
ccgctgatcctggccgcccgcctagctgtggagggaatggtggcagaactgatcaactgc
caagcagatgtgaacgcagtggatgaccatgggaaatctgctcttcactgggcagctgct
gtcaataacgtggaggcaacccttttgctgttgaaaaacggggccaaccgagacatgcag
gacaacaaggaagagacacctctgtttcttgctgcccgggagggaagctatgaagcagcc
aagatcctgttagaccattttgccaatcgggacatcacagaccacatggatcgtcttccc
cgggatgtggctcgagaccgcatgcaccatgacattgtgcgcctcctggatgagtacaat
gtgacaccaagccctccaggcactgtgctgacttctgccctctcacctgtgatctgtggg
cccaacagatctttcctcagcctaaagcataccccaatgggcaagaagcctagacggccc
aataccaagagtaccatgcccactagcctccctaaccttgccaaggagggcaaggatgcc
aagggtagtaggaggaaaaagtctctgagtgacaagggtcagctgtctgagagctcagtg
actttatcccccgttgattccttagaatctcctcacacatatgtttctgacaccacatcc
tctccaatgattacatcccctggaatcttacaggcctcgcccaaccctatgttggccact
gctgccccccctgccccagtccatgcccagcatgcactgtctttctctaacctgcatgaa
atgcagcctttggctcatggggccagcactgtgcttccctcagtgagccagctgctgtcc
caccaccacattgtccccccaggcagtagcagtgcgggaagcttgagtaggctccatcct
gtcactgttccggcagattggatgaaccgcatggagatgaatgagacccagtacaatgag
atgtttggtatggttctggctccagctgagggcacgcaccctggcatagctccccagagc
aggccacctgaagggaagcacataactacccctcgggagcctttgccccccattgtgact
ttccagctaatccccaaaggcaatattgcccaaccggctgggactccccagcctcagtcc
aactgccctcctcctgttgcaggccctgtgcccaccatgtaccagattccagaaatggct
cgtttgcccagtatggctttccccactgccatgatgccccagcaggatgggcaggttgct
cagaccattctccctgcctatcatccttttccagcctctgtgggcaagtaccctacacca
ccttcacagcatagttatgcttcctcaaatgctgctgagcgaacacccagtcacagtggt
cacctgcagggtgaacatccctacctgacaccatccccagagtctcctgaccagtggtca
agttcatcaccccactctgcttctgactggtcagatgtgaccaccagccctacccctggg
ggtgctggaggaggtcagcggggacctggaacacacatgtctgagccaccacgcagcaac
atgcaggtttatgcatga
DBGET
integrated database retrieval system
