Ursus arctos (brown bear): 113245266
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Entry
113245266 CDS
T05909
Symbol
ASH1L
Name
(RefSeq) histone-lysine N-methyltransferase ASH1L isoform X2
KO
K06101
[histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:
2.1.1.354
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00310
Lysine degradation
uah01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
113245266 (ASH1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uah03036
]
113245266 (ASH1L)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
113245266 (ASH1L)
Chromosome and associated proteins [BR:
uah03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
113245266 (ASH1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SET
BAH
AWS
Bromodomain
PHD_5
PHD
HTH_animal
DUF7877
PHD_2
Motif
Other DBs
NCBI-GeneID:
113245266
NCBI-ProteinID:
XP_026340985
LinkDB
All DBs
Position
Unknown
AA seq
2965 aa
AA seq
DB search
MDPRNTAMLGLGSDSEGFSRKSPSALGTGTVVSKREGELENSTKEEEDLRKWNRERSSEA
GKEDGVTGAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHPR
KALKSGKMTDEKNERCPSKRDPSKLYKKTGDVAAVECQSEESIHLHSQGENSPLSKKLSP
VHSEMTDYINAASSTLVGGRDPDLKDRALLNGGTSVTEKLAQLIATCPPSKSSKTKPKKL
GTGTTAGLVSKDLIRKAGVGSVAGIIHKDLIKKPAISTAVGLVTKDPGKKPVFNATVGLV
NKDSVKKLGAGTTAVFINKDLGRKPGTVTTVGLLSKDSGKKLGIGIVPGLVNKESGKKLG
LGTVVGLVNKDLGKKLSSTVGLVAKDCAKKIVANSTMGLVTKDMGKKLVSCSMAGLVSKD
AINLKAEALLPTQEPLKASCSTNISSHESQELPESLKDSTTSKTFEKNVIRQSKESILEK
FSVRKEIINLEKEMFNEGTCIQQDSFSSSDRGPYETSKHEKQPPVYCTSPDFQMGAASDA
STAKSPFSAVGESNLPSPSPTVSVNPLTRSPPETSSQLAPNPLLLSPTTELMEEISESVG
KNQFTSESTHLNIGHRSVGHSMSIECKGIDKELTDSKTTHIDIPRISSSLGKKPSLTSES
SIHTITPSVVNFTSLFSNKPFLKLGAVTASDKHCQVAESLSTSLQSKPLKKRKGRKPRWT
KVVARSTCRSPKGLELERSELFKNVSCSSLSNSNSEPAKFMKNIGPSSFVDHDFLKRRLP
KLSKSTTPSLALLTDSEKPSHKAFATHKLSSSMCVSSDLLSDIYKPKRGRPKAKEMPQLE
GPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSP
VKMKPPVLSVAPFVATESPSKLESESDNRRSSSDFFESEDQLQDPDDLDDSRRPAVCTMS
DLEMEPDKKITKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHN
TVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGILSGSPTSLAVLEQTAQQA
AGSALGQILPPLLPSSASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHLHS
RQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPISESHSDETIPSD
SGIGTDNNSTSDRAEKFCGQKKRRHSFEHVSLIPPETSTVLSSLKEKHKHKCKRRNHDYL
SYDKMKRQKRKRKKKYPQLRSRQDPDFIADLEELISRLSEIRITHRSHHFIPRDLLPTIF
RINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYP
SYGMPYSPSPLTATPLGLGYYGRYPPTLYPPPPSPSFTPPLPPPSYMHAGHLLLNPTKYH
KKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSSEQPQV
SMDTGSSRSVLESLKRYRFGKETVGERYKHKEKHRCHMSCPHLSPSKSLINREEQWVHRE
PSESSPLALGLQTPLQIDCSESSPSLSLGGFTPNSDPASSDEHTNLFTSAIVQGSCRVSN
PNSSGRKKLTDSPGLFSAQDTSLTRPHRKEPLPSSERAVQTMTGSQPTSEKSSQRPSEST
NCSPTRKRSSSESTSSTVNGVPSRSPRLLASGDDSVDSLLQRMVQHEDHEPLEKNIDAVI
ASASGPPSSSPGHSHSKERALGKPDSLLVPTAPTDSCSSSISLLSEKLPSSCSPHHIKRS
VVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPL
QAVVSMQAFQAARFVSPDSNEGEERAALPLRPDTVTDVIEAVVQSVNLSPEHKKGLKRKS
WLLEEQTKKKQKPFPEEEQEHTKSFTEAAVEIPSPPETPAKLPEPENTLQPVLSLIPREK
KAPRPPKKKYQKAGLYSDVYKTTDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLR
QKRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPEDD
TGKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEP
LKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHS
CDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGII
GGKSQRVNGLTSSKSSQPVATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSENINTPTRLT
PQIQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNLHSASLYTRWNGICRDD
GNIKSDVFMTQFSALQTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSR
QALAAPLLNLPPKKKNADYYEKISEPLDLATIERQILTGHYKTVEAFDADMLKVFRNAEK
YYGRKSPIGRDVCRLRKTYYNARHEASAQIDEIVGETASEADSSETSVSEKENVHEKDDD
VIRCVCGLHKDEGLMIQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPH
YAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRI
EKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDL
YTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKRDF
SPHYVPDNYKRNGGRSSWKSERPKPPLKDLGQEDDALPLIEEVLASQEQAADELPSLEEP
EREGAPAEVGEGEKKPEESSQESQPASTPEERRHSQRERLNQILLSLLEKIPGKNAIDVT
YLLEEGSGRKLRRRTLFIPENSFRK
NT seq
8898 nt
NT seq
+upstream
nt +downstream
nt
atggaccctagaaatactgctatgttaggattgggttctgactctgaagggttttcaagg
aagagtccctctgccctcggtactggcacggtggtcagcaagagagaaggagagctagag
aacagcacgaaagaggaagaggaccttcgtaagtggaatcgggagagaagcagtgaagca
gggaaggaggatggtgtgactggtgcacagcagcagttttcagtgaaagaaacaaacttt
tcagagggaaacttaaaattgaaaattggccttcaggctaagagaactaaaaaacctcca
aagaacttggagaactatgtatgtcgacctgccataaaaacaactatcaagcacccaagg
aaagcacttaaaagtgggaagatgacagatgagaagaatgagcgctgtccttcaaaacgg
gacccttcaaagttgtacaagaaaacaggtgatgttgcagccgttgaatgccagtctgaa
gagagcatccatcttcattcacagggagaaaacagtcctttgtctaagaagctttctcca
gtgcactcagaaatgacagattacattaatgcggcatcatctactcttgttggtggccgg
gatcctgatttaaaggacagagcattacttaatggaggaactagtgtgacagaaaagttg
gcacagctcattgcaacttgtcctccctctaagtcttccaagactaaaccgaagaagtta
ggaactggcactactgcgggattggttagcaaggatttgatcaggaaagcaggtgttggc
tctgtagctggaataatacataaggacttaataaaaaaaccagctatcagcacagcagtt
ggattggtaactaaagatcctgggaaaaagccagtgtttaatgcaacagtaggattggtc
aataaggactctgtgaaaaaactaggagctggcactacagcagtattcattaataaagac
ttaggcagaaagccagggactgtcactacagtaggactgctgagcaaggattcaggaaag
aagctaggaattggtattgttccaggtttagtgaataaggaatctggaaagaagttagga
cttggcactgtggttggactggttaataaagacttgggcaagaagttgagttctactgtc
ggcctggtggccaaggactgtgcaaagaagattgtagccaattcaacaatgggattagtt
actaaggacatgggaaagaaactagtgagttgttcaatggcaggactggtcagtaaagat
gccataaaccttaaagccgaagcactgctccctactcaggaaccactaaaggcttcttgt
agtacaaacatcagtagtcatgaaagtcaggaacttcctgaatccctgaaagatagtacc
accagcaaaacttttgagaagaatgttatacggcagagtaaagaaagcatattggaaaag
ttctcagttcgaaaagaaatcattaatttggagaaagaaatgtttaatgaaggaacgtgc
attcagcaggacagtttctcatccagtgacagggggccttatgaaacctcaaagcatgaa
aagcaacctcccgtgtattgcacttctccggactttcaaatgggagctgcttctgatgca
tctacagcaaaatccccttttagtgcagtaggagaaagcaatctcccttccccatcacct
actgtatctgttaatcctttaaccagaagtccccctgaaacttcttcacagttggcccct
aatccgttacttttgagtcctaccacagaattaatggaagaaatttctgaatctgttggg
aagaaccagtttacttctgaaagtacccatttgaacattggtcataggtctgtgggtcac
agcatgagtattgaatgtaaagggattgataaagagctaactgattcaaaaactacacat
atagatattccaagaataagctcttccctgggaaaaaagccaagtttgacttctgaatcc
agtattcacacaataaccccttcagttgttaacttcactagtttatttagtaacaagccc
tttctaaaacttggtgcggtcactgcgtctgacaaacactgccaggttgctgaaagccta
agcactagtttgcagtccaaaccattaaaaaaaaggaaaggaagaaaacctcggtggact
aaagtggtggcaaggagcacatgccggtctccaaaagggctagaattagaaagatcagag
ctttttaaaaatgtttcatgtagctcactatcgaatagtaattctgagccagccaagttt
atgaaaaacattggaccatcttcgtttgtagatcatgacttccttaaacgtcgattgcca
aagttgagcaagtccacaactccatctcttgctctcttaactgatagtgaaaaaccatct
cacaaggcttttgctactcacaaactatcctccagtatgtgtgtctctagtgacctgttg
tctgatatttacaagcccaaaagaggaagacctaaagctaaggagatgcctcaactggaa
ggtccacctaaaaggactttaaaaatccctgcctctaaagttttttctttgcagtctaag
gaagaacaggaacccccaattttacagccagaaattgaaattccttccttcaaacaaagc
ctttctgtgtctccttttccaaaaaagcgaggcagaccgaagaggcagatgaggtcaccg
gtcaagatgaagccacctgtactgtcagtggctccgtttgttgccaccgagagtccaagc
aagctagagtctgaaagtgacaaccgtcgaagcagcagtgatttctttgagagtgaggat
cagcttcaggacccagatgatctggacgacagtcgtaggccagctgtctgcaccatgagt
gaccttgagatggaaccagataaaaaaattaccaagagaaacaatggacaattaatgaaa
acaattatccgcaaaataaataaaatgaagactttaaagaggaagaagctgttgaatcag
attctttccagctctgtagaatcaagtaataaagggaaagtgcaatccaaactccacaac
acagtgtcgagtcttgcggctacgtttggctctaaattgggccaacagataaatgtcagc
aagaaaggaaccatttacataggaaagagaaggggtcgaaaaccaaaaactgttttaaat
ggcattctttctggtagccctaccagccttgctgtccttgagcaaactgctcagcaggca
gctggctcagcattaggacagatccttccccctttactgccttcgtctgctagtagttct
gagattcttccatcacctatttgctctcagtcttctgggactagtggaggtcagagccct
gtaagtagtgacgcaggcttcgttgaacccagttcagtgccatatttgcatttacactcc
agacagggcagcatgattcagactcttgcaatgaagaaggcctcaaaggggaggaggcga
ctctctcctcctactttgttgccaaattctccttcacacttgagtgaactcacctctctg
aaagaagctactccttctcccattagtgagtctcacagtgatgagaccattcccagtgat
agtggaattggaacagataataacagcacatcagacagagcagagaaattttgtggacag
aaaaagaggaggcattcttttgaacatgtttctctgattccccctgaaacctctacagtc
ctgagcagtcttaaagaaaaacataaacataaatgtaagcgcaggaatcacgattacctc
agctatgacaagatgaaaaggcagaaacgaaaacggaaaaagaaatacccccagctccga
agcagacaggatccggacttcatcgcagatctggaggaattgataagtcgtctgagcgaa
attcgaatcacccatcgaagtcatcattttatcccccgagacctgctgccaactattttt
cgaatcaactttaatagtttctatacacatccttctttccccttagaccctttgcactac
attcgaaaacccgacttaaaaaagaagagagggagacctcctaagatgagggaggcaatg
gcggagatgcccttcatgcatagcctcagttttcctctttctagtactggattctatcct
tcctatggcatgccttattctccctcaccccttacagccactcccctaggattaggttac
tatggaaggtaccctcccactctctatcctcctcctccttctccttctttcaccccccca
cttccacctccttcctatatgcatgctggtcatttacttctcaatcccaccaaataccat
aagaaaaagcataaactacttcgacaggaggcctttctcacaaccagcaggactcccctc
ctttccatgagtacctaccctagcgttcctcccgagatggcctatggttggatggtcgag
cacaaacataggcaccgtcacaagcacagagaacaccgttcttctgagcaaccccaggtt
tccatggacactggctcttccagatctgttttggagtctttgaaacgctatcgatttgga
aaggaaactgttggagagcgatataaacataaggaaaagcaccgatgtcatatgtcctgc
cctcatctctctccttccaaaagcttaataaatagagaagagcagtgggtccaccgagag
ccttcagaatctagtccattggctttgggattgcaaacacctttacagattgactgttca
gaaagttctccaagtttatcccttggaggattcactcccaactctgatcctgccagcagt
gatgaacacacaaaccttttcacaagtgcaatagtgcaaggcagctgcagagtctccaac
cctaactccagtggccggaagaaattaactgacagtcctggactgttttccgcacaggac
acttcactaactcggcctcacagaaaggagccactgccttccagcgaaagggcagtacag
accatgacaggttcccagccaacctcagagaagtcttcccagcgaccatcagagagcaca
aactgtagccctacccggaagaggtcgtcatctgagagtacttcatcaacagtaaacgga
gttccctctcgaagtccaagattgcttgcttctggggatgactctgtggatagtctgctg
cagcggatggtccaacatgaggaccatgagcccctggagaagaatatagatgctgtgatt
gcatctgcctcagggccaccttcctccagtccaggccacagccacagcaaggagcgagcc
ctgggaaaaccagacagcctcctggtgcccacagcccccactgactcttgcagtagcagc
atctcactcctgtctgagaagttgccgagcagctgctcgccccaccatatcaagagaagt
gtcgtggaagccatgcagcgccaagctcggaaaatgtgcaattatgacaaaatcttggcc
actaagaaaaacctggaccatgtcaataaaatattaaaagccaaaaaactccagagacag
gccaggacagggaataactttgtgaaacgaagaccggggcgacctcggaaatgccccctc
caggctgtggtgtcaatgcaagcattccaggctgcccggtttgtcagccccgactcgaat
gaaggcgaagaaagagcagcgctgcccctccgtcccgacacagttacggatgtcattgag
gctgttgtgcagagcgtaaacctgagtccagaacataagaaggggctgaagaggaaaagt
tggctgttggaagaacagaccaagaaaaagcagaagccattcccagaggaagagcaagaa
catactaagagctttactgaagcagcagttgagattcccagtcctcctgaaaccccagcc
aagcttcccgaacctgaaaataccttgcagcctgtgctttctctcatcccaagggaaaag
aaggccccacgtcccccaaagaagaagtatcagaaagcagggctgtattctgacgtttac
aaaactacagacccaaagagccgattgatccaattaaagaaagagaagctggaatacact
ccaggagagcacgagtatgggttgttcccagcccccattcatgttggaaagtatctgagg
caaaagagaattgacttccagcttccctatgacatcctttggcagtggaaacacaatcag
ctatacaaaaagccagatgtcccactgtataaaaaaatccgttcaaatgtctatgttgat
gtcaagcccctttctgggtacgaggccaccacctgtaactgtaagaagccagaagatgac
accgggaagggctgtgtggacgactgcctcaatagaatgatctttgctgagtgttccccc
aacacttgcccctgtggtgagcagtgctgtaaccagaggatacaaaggcatgagtgggtg
cagtgtctagaacgatttcgagctgaggagaaaggttggggaatcagaaccaaagaaccc
ctgaaagctgggcagttcatcattgaatacctaggggaggttgtcagcgagcaggagttc
aggaataggatgatcgagcagtatcataatcacagtgaccactattgcctgaacctggat
agtgggatggtgatcgacagttaccggatggggaatgaggcccgattcatcaaccacagc
tgtgacccaaactgtgaaatgcagaaatggtctgtcaatggagtgtaccggattggactg
tatgctcttaaagatatgccagctggtaccgagctcacttacgattacaacttccattcc
tttaatgtggaaaaacagcaattgtgtaagtgtggctttgagaaatgtcgaggaatcatc
ggaggcaagagtcagcgtgtgaacggactcaccagcagcaagagcagccagcccgtggct
acacataaaaagtccggacggtcaaaagagaagagaaagtccaagcacaagctgaagaaa
aggagaggccacctctccgaagaacccagtgaaaacatcaacacgccaacaaggttgacg
ccccaaatacaaatgaagccaatgtctaatcgagagaggaactttgtgttaaagcatcat
gtattcttggtccgaaactgggagaagattcggcagaaacaagaggaagtaaagcacacc
agcgataatctccactcagcatcattatatacccgctggaatggcatctgccgagatgat
gggaacatcaagtctgacgtcttcatgacccagttctccgccctgcagacagcacggtcg
gttcgaacaagacggctggcagcagcagaggaaaacattgaggtggcgcgggcagcccgc
ctcgcccaaatcttcaaagagatctgtgatggcatcatctcctacaaagattcttcccga
caagctctggcagcaccccttttgaacctccccccaaagaaaaagaatgctgattactac
gagaagatctccgagcccctggacctggccaccatagagaggcagatcctcaccggccat
tacaagaccgtggaggcctttgatgctgacatgctcaaggtgtttcggaatgctgagaag
tactatgggcgtaaatccccaattgggagagacgtttgccgcctacggaagacctactac
aatgccaggcacgaggcatcagcccagattgatgaaattgtgggagagacagcaagtgag
gccgacagcagcgagacgtctgtctccgagaaggagaacgtgcacgagaaggacgacgat
gtgatccgctgtgtctgcggcctgcacaaggatgaaggcctcatgatccagtgcgacaag
tgcatggtgtggcagcactgtgactgtatgggggtgaactcggacgtggagcactacctt
tgtgagcagtgcgacccgaggcctgtggacagagaggtacccatgattcctcggccccac
tatgcccagcccggctgtgtctacttcatctgtttgctccgagatgacctgttgcttcgt
caaggcgactgcgtgtacctgatgcgggatagccggcgcacacctgatggccacccagtc
cgccagtcctaccgactgttgtcgcacattaaccgagacaaactggacatcttccgcatt
gagaagctttggaagaatgaaaaagaggaacgttttgccttcggtcatcactacttccgc
ccccacgagacccaccactctccatcccgccgtttctatcacaatgagctgtttcgggtg
ccactctacgagatcattcccttggaggctgtggtagggacctgctgtgtcctggacctt
tatacgtattgtaaagggagacccaaaggagtgaaggagcaagatgtgtacatctgtgac
taccggctggacaagtccgcacacctgttctacaagatccaccggaaccgctaccctgtc
tgcaccaagccctatgcctttgaccacttccccaagaagctcacgcccaaaagagatttc
tcacctcattacgtcccagacaactacaagaggaacggagggcggtcatcctggaagtcc
gagcgcccaaagccacccctaaaagacctgggccaggaggatgatgctctgcccttgatt
gaagaggttctggccagccaggaacaggccgccgacgagctgcccagcctggaggagccg
gaacgggagggggcccctgctgaagtgggcgagggtgagaagaagccagaggagagtagt
caggagtctcagccggcctctacccctgaggagcggcggcacagccagcgggaacgactc
aaccagatcttactcagtctccttgaaaaaatccctgggaaaaatgccatcgacgtgacc
tacttgctggaggaggggtcaggcaggaagctgcgaaggcgcactctgttcatcccagaa
aacagctttcggaagtga
DBGET
integrated database retrieval system
