Ursus arctos horribilis (North American brown bear): 113247020
Help
Entry
113247020 CDS
T05909
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah01522
Endocrine resistance
uah01524
Platinum drug resistance
uah04010
MAPK signaling pathway
uah04012
ErbB signaling pathway
uah04014
Ras signaling pathway
uah04015
Rap1 signaling pathway
uah04022
cGMP-PKG signaling pathway
uah04024
cAMP signaling pathway
uah04062
Chemokine signaling pathway
uah04066
HIF-1 signaling pathway
uah04068
FoxO signaling pathway
uah04071
Sphingolipid signaling pathway
uah04072
Phospholipase D signaling pathway
uah04114
Oocyte meiosis
uah04140
Autophagy - animal
uah04148
Efferocytosis
uah04150
mTOR signaling pathway
uah04151
PI3K-Akt signaling pathway
uah04210
Apoptosis
uah04218
Cellular senescence
uah04261
Adrenergic signaling in cardiomyocytes
uah04270
Vascular smooth muscle contraction
uah04350
TGF-beta signaling pathway
uah04360
Axon guidance
uah04370
VEGF signaling pathway
uah04371
Apelin signaling pathway
uah04380
Osteoclast differentiation
uah04510
Focal adhesion
uah04520
Adherens junction
uah04540
Gap junction
uah04550
Signaling pathways regulating pluripotency of stem cells
uah04611
Platelet activation
uah04613
Neutrophil extracellular trap formation
uah04620
Toll-like receptor signaling pathway
uah04621
NOD-like receptor signaling pathway
uah04625
C-type lectin receptor signaling pathway
uah04650
Natural killer cell mediated cytotoxicity
uah04657
IL-17 signaling pathway
uah04658
Th1 and Th2 cell differentiation
uah04659
Th17 cell differentiation
uah04660
T cell receptor signaling pathway
uah04662
B cell receptor signaling pathway
uah04664
Fc epsilon RI signaling pathway
uah04666
Fc gamma R-mediated phagocytosis
uah04668
TNF signaling pathway
uah04713
Circadian entrainment
uah04720
Long-term potentiation
uah04722
Neurotrophin signaling pathway
uah04723
Retrograde endocannabinoid signaling
uah04724
Glutamatergic synapse
uah04725
Cholinergic synapse
uah04726
Serotonergic synapse
uah04730
Long-term depression
uah04810
Regulation of actin cytoskeleton
uah04910
Insulin signaling pathway
uah04912
GnRH signaling pathway
uah04914
Progesterone-mediated oocyte maturation
uah04915
Estrogen signaling pathway
uah04916
Melanogenesis
uah04917
Prolactin signaling pathway
uah04919
Thyroid hormone signaling pathway
uah04921
Oxytocin signaling pathway
uah04926
Relaxin signaling pathway
uah04928
Parathyroid hormone synthesis, secretion and action
uah04929
GnRH secretion
uah04930
Type II diabetes mellitus
uah04933
AGE-RAGE signaling pathway in diabetic complications
uah04934
Cushing syndrome
uah04935
Growth hormone synthesis, secretion and action
uah04960
Aldosterone-regulated sodium reabsorption
uah05010
Alzheimer disease
uah05020
Prion disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05034
Alcoholism
uah05132
Salmonella infection
uah05133
Pertussis
uah05135
Yersinia infection
uah05140
Leishmaniasis
uah05142
Chagas disease
uah05145
Toxoplasmosis
uah05152
Tuberculosis
uah05160
Hepatitis C
uah05161
Hepatitis B
uah05163
Human cytomegalovirus infection
uah05164
Influenza A
uah05165
Human papillomavirus infection
uah05166
Human T-cell leukemia virus 1 infection
uah05167
Kaposi sarcoma-associated herpesvirus infection
uah05170
Human immunodeficiency virus 1 infection
uah05171
Coronavirus disease - COVID-19
uah05200
Pathways in cancer
uah05203
Viral carcinogenesis
uah05205
Proteoglycans in cancer
uah05206
MicroRNAs in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05208
Chemical carcinogenesis - reactive oxygen species
uah05210
Colorectal cancer
uah05211
Renal cell carcinoma
uah05212
Pancreatic cancer
uah05213
Endometrial cancer
uah05214
Glioma
uah05215
Prostate cancer
uah05216
Thyroid cancer
uah05218
Melanoma
uah05219
Bladder cancer
uah05220
Chronic myeloid leukemia
uah05221
Acute myeloid leukemia
uah05223
Non-small cell lung cancer
uah05224
Breast cancer
uah05225
Hepatocellular carcinoma
uah05226
Gastric cancer
uah05230
Central carbon metabolism in cancer
uah05231
Choline metabolism in cancer
uah05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
uah05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113247020 (MAPK1)
04012 ErbB signaling pathway
113247020 (MAPK1)
04014 Ras signaling pathway
113247020 (MAPK1)
04015 Rap1 signaling pathway
113247020 (MAPK1)
04350 TGF-beta signaling pathway
113247020 (MAPK1)
04370 VEGF signaling pathway
113247020 (MAPK1)
04371 Apelin signaling pathway
113247020 (MAPK1)
04668 TNF signaling pathway
113247020 (MAPK1)
04066 HIF-1 signaling pathway
113247020 (MAPK1)
04068 FoxO signaling pathway
113247020 (MAPK1)
04072 Phospholipase D signaling pathway
113247020 (MAPK1)
04071 Sphingolipid signaling pathway
113247020 (MAPK1)
04024 cAMP signaling pathway
113247020 (MAPK1)
04022 cGMP-PKG signaling pathway
113247020 (MAPK1)
04151 PI3K-Akt signaling pathway
113247020 (MAPK1)
04150 mTOR signaling pathway
113247020 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113247020 (MAPK1)
04148 Efferocytosis
113247020 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
113247020 (MAPK1)
04210 Apoptosis
113247020 (MAPK1)
04218 Cellular senescence
113247020 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113247020 (MAPK1)
04520 Adherens junction
113247020 (MAPK1)
04540 Gap junction
113247020 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
113247020 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113247020 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113247020 (MAPK1)
04613 Neutrophil extracellular trap formation
113247020 (MAPK1)
04620 Toll-like receptor signaling pathway
113247020 (MAPK1)
04621 NOD-like receptor signaling pathway
113247020 (MAPK1)
04625 C-type lectin receptor signaling pathway
113247020 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
113247020 (MAPK1)
04660 T cell receptor signaling pathway
113247020 (MAPK1)
04658 Th1 and Th2 cell differentiation
113247020 (MAPK1)
04659 Th17 cell differentiation
113247020 (MAPK1)
04657 IL-17 signaling pathway
113247020 (MAPK1)
04662 B cell receptor signaling pathway
113247020 (MAPK1)
04664 Fc epsilon RI signaling pathway
113247020 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
113247020 (MAPK1)
04062 Chemokine signaling pathway
113247020 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
113247020 (MAPK1)
04929 GnRH secretion
113247020 (MAPK1)
04912 GnRH signaling pathway
113247020 (MAPK1)
04915 Estrogen signaling pathway
113247020 (MAPK1)
04914 Progesterone-mediated oocyte maturation
113247020 (MAPK1)
04917 Prolactin signaling pathway
113247020 (MAPK1)
04921 Oxytocin signaling pathway
113247020 (MAPK1)
04926 Relaxin signaling pathway
113247020 (MAPK1)
04935 Growth hormone synthesis, secretion and action
113247020 (MAPK1)
04919 Thyroid hormone signaling pathway
113247020 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
113247020 (MAPK1)
04916 Melanogenesis
113247020 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
113247020 (MAPK1)
04270 Vascular smooth muscle contraction
113247020 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
113247020 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
113247020 (MAPK1)
04725 Cholinergic synapse
113247020 (MAPK1)
04726 Serotonergic synapse
113247020 (MAPK1)
04720 Long-term potentiation
113247020 (MAPK1)
04730 Long-term depression
113247020 (MAPK1)
04723 Retrograde endocannabinoid signaling
113247020 (MAPK1)
04722 Neurotrophin signaling pathway
113247020 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
113247020 (MAPK1)
04380 Osteoclast differentiation
113247020 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
113247020 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113247020 (MAPK1)
05206 MicroRNAs in cancer
113247020 (MAPK1)
05205 Proteoglycans in cancer
113247020 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
113247020 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
113247020 (MAPK1)
05203 Viral carcinogenesis
113247020 (MAPK1)
05230 Central carbon metabolism in cancer
113247020 (MAPK1)
05231 Choline metabolism in cancer
113247020 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113247020 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
113247020 (MAPK1)
05212 Pancreatic cancer
113247020 (MAPK1)
05225 Hepatocellular carcinoma
113247020 (MAPK1)
05226 Gastric cancer
113247020 (MAPK1)
05214 Glioma
113247020 (MAPK1)
05216 Thyroid cancer
113247020 (MAPK1)
05221 Acute myeloid leukemia
113247020 (MAPK1)
05220 Chronic myeloid leukemia
113247020 (MAPK1)
05218 Melanoma
113247020 (MAPK1)
05211 Renal cell carcinoma
113247020 (MAPK1)
05219 Bladder cancer
113247020 (MAPK1)
05215 Prostate cancer
113247020 (MAPK1)
05213 Endometrial cancer
113247020 (MAPK1)
05224 Breast cancer
113247020 (MAPK1)
05223 Non-small cell lung cancer
113247020 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113247020 (MAPK1)
05170 Human immunodeficiency virus 1 infection
113247020 (MAPK1)
05161 Hepatitis B
113247020 (MAPK1)
05160 Hepatitis C
113247020 (MAPK1)
05171 Coronavirus disease - COVID-19
113247020 (MAPK1)
05164 Influenza A
113247020 (MAPK1)
05163 Human cytomegalovirus infection
113247020 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
113247020 (MAPK1)
05165 Human papillomavirus infection
113247020 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
113247020 (MAPK1)
05135 Yersinia infection
113247020 (MAPK1)
05133 Pertussis
113247020 (MAPK1)
05152 Tuberculosis
113247020 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
113247020 (MAPK1)
05140 Leishmaniasis
113247020 (MAPK1)
05142 Chagas disease
113247020 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
113247020 (MAPK1)
05020 Prion disease
113247020 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
113247020 (MAPK1)
09165 Substance dependence
05034 Alcoholism
113247020 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113247020 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
113247020 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
113247020 (MAPK1)
04934 Cushing syndrome
113247020 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113247020 (MAPK1)
01524 Platinum drug resistance
113247020 (MAPK1)
01522 Endocrine resistance
113247020 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113247020 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uah03036
]
113247020 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uah04147
]
113247020 (MAPK1)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
113247020 (MAPK1)
Protein kinases [BR:
uah01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
113247020 (MAPK1)
Chromosome and associated proteins [BR:
uah03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
113247020 (MAPK1)
Exosome [BR:
uah04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
113247020 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
113247020
NCBI-ProteinID:
XP_026343610
LinkDB
All DBs
Position
Unknown
AA seq
360 aa
AA seq
DB search
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtggggccgcgctacaccaacctctcgtacatcggcgagggcgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatcagtccttttgag
caccagacctactgccagagaaccctgagggagataaaaatcttactgcgcttcagacat
gagaacatcattggaatcaatgatattattcgagcaccaaccatcgagcaaatgaaagat
gtgtatatagtacaggacctcatggaaacagatctatacaagctcttgaagacgcaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaatgtactgcaccgtgacctcaaaccttccaacctgctgctcaacaccacc
tgcgatctcaagatctgtgactttggcttggcccgtgttgcagatccggaccatgatcac
acagggttcctgacggagtatgtagccacacgttggtacagggctccggaaattatgttg
aattccaagggctataccaagtccattgatatttggtctgtaggctgcattctggcagag
atgctgtccaacaggcccatcttcccggggaagcattatctcgaccagctgaaccacatt
ctgggtattcttggatccccatcacaggaagacctgaactgtataataaatttaaaagct
agaaactacttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactccaaagctctggatttactggacaaaatgttgacattcaaccctcacaag
aggattgaagtagaacaggctctggcccatccatatctggagcagtattatgacccaagc
gatgagcccatcgctgaggcgccattcaagtttgacatggagctggatgacctgcccaag
gaaaagctcaaagagctcatcttcgaagagacagctagattccagccgggatacagatct
taa
DBGET
integrated database retrieval system