Ursus arctos (brown bear): 113250494
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Entry
113250494 CDS
T05909
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00230
Purine metabolism
uah00670
One carbon pool by folate
uah01100
Metabolic pathways
uah01523
Antifolate resistance
Module
uah_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113250494 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
113250494 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
113250494 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uah04147
]
113250494 (ATIC)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
113250494 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
113250494 (ATIC)
Exosome [BR:
uah04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
113250494 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
113250494
NCBI-ProteinID:
XP_026347799
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPSQLALFSVSDKTGLVEFARNLTAVGLDLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVSTEMKSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAASSFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPVS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILSKKKNG
SYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIDRTLFSNIVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVDKLSEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaaaacgggccttgtggaattt
gccagaaacctaactgctgttggtttggatctgatcgcctccggagggactgcaaaggct
ctcagggatgcggggctggcagtcagagatgtctctgagctgacggggtttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgtcgtc
tgtaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctactgagagcagcagccaaaaaccatgct
cgagtgacagtagtgtgtgaacccgaggactacgcggctgtgtccacagagatgaagagc
tccgacagcaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacggcacaatatgatgaagcaatttcagattacttcaggagacagtatagtaaagga
atatctcagatgcctttgaggtatggaatgaaccctcatcaaactcctgcccagttatac
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggcattcct
gccgcttcctctttcaaacatgtcagcccggcaggtgctgctgttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctgtataaaacccttacacccgtatca
actgcatatgcaagagcaagaggggctgataggatgtcttcatttggtgattttgttgca
ttatctgatgtctgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgaagatgaagctttgaaaatactttctaaaaagaaaaatggg
agctactgtgttcttcagatggatcagtcttacaatccagatgaaaatgaagtacgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaggacattattt
agcaacattgtgaccaagaataaagatttgccagagtctgcgctcagagacctcattgta
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggtcag
gttatcggcattggagcaggacagcagtcccgaatacactgcacccgccttgcaggggat
aaggcaaactattggtggcttagacatcatccacaggttctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaagatttgataaagtggaaggcattgtttgaggaagtgcctgaattattaact
gaagcagagaagaaggaatgggttgacaaacttagtgaagtttctgtcagctctgatgcc
ttttttccttttagggataatgtagacagagctaaaaggagtggtgtggcctacattgct
gctccttctggttctgctgctgacaaagttgtgattgaggcttgcgatgaactgggaata
atccttgctcatacgaatcttcggctctttcatcactga
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