Ursus arctos (brown bear): 113251972
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Entry
113251972 CDS
T05909
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
KO
K03083
glycogen synthase kinase 3 beta [EC:
2.7.11.26
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah04012
ErbB signaling pathway
uah04062
Chemokine signaling pathway
uah04110
Cell cycle
uah04150
mTOR signaling pathway
uah04151
PI3K-Akt signaling pathway
uah04310
Wnt signaling pathway
uah04340
Hedgehog signaling pathway
uah04360
Axon guidance
uah04390
Hippo signaling pathway
uah04510
Focal adhesion
uah04517
IgSF CAM signaling
uah04550
Signaling pathways regulating pluripotency of stem cells
uah04657
IL-17 signaling pathway
uah04660
T cell receptor signaling pathway
uah04662
B cell receptor signaling pathway
uah04722
Neurotrophin signaling pathway
uah04728
Dopaminergic synapse
uah04910
Insulin signaling pathway
uah04916
Melanogenesis
uah04917
Prolactin signaling pathway
uah04919
Thyroid hormone signaling pathway
uah04931
Insulin resistance
uah04932
Non-alcoholic fatty liver disease
uah04934
Cushing syndrome
uah04935
Growth hormone synthesis, secretion and action
uah04936
Alcoholic liver disease
uah05010
Alzheimer disease
uah05020
Prion disease
uah05022
Pathways of neurodegeneration - multiple diseases
uah05135
Yersinia infection
uah05160
Hepatitis C
uah05162
Measles
uah05163
Human cytomegalovirus infection
uah05165
Human papillomavirus infection
uah05167
Kaposi sarcoma-associated herpesvirus infection
uah05200
Pathways in cancer
uah05210
Colorectal cancer
uah05213
Endometrial cancer
uah05215
Prostate cancer
uah05217
Basal cell carcinoma
uah05224
Breast cancer
uah05225
Hepatocellular carcinoma
uah05226
Gastric cancer
uah05415
Diabetic cardiomyopathy
uah05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
113251972 (GSK3B)
04310 Wnt signaling pathway
113251972 (GSK3B)
04340 Hedgehog signaling pathway
113251972 (GSK3B)
04390 Hippo signaling pathway
113251972 (GSK3B)
04151 PI3K-Akt signaling pathway
113251972 (GSK3B)
04150 mTOR signaling pathway
113251972 (GSK3B)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
113251972 (GSK3B)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
113251972 (GSK3B)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113251972 (GSK3B)
04550 Signaling pathways regulating pluripotency of stem cells
113251972 (GSK3B)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
113251972 (GSK3B)
04657 IL-17 signaling pathway
113251972 (GSK3B)
04662 B cell receptor signaling pathway
113251972 (GSK3B)
04062 Chemokine signaling pathway
113251972 (GSK3B)
09152 Endocrine system
04910 Insulin signaling pathway
113251972 (GSK3B)
04917 Prolactin signaling pathway
113251972 (GSK3B)
04935 Growth hormone synthesis, secretion and action
113251972 (GSK3B)
04919 Thyroid hormone signaling pathway
113251972 (GSK3B)
04916 Melanogenesis
113251972 (GSK3B)
09156 Nervous system
04728 Dopaminergic synapse
113251972 (GSK3B)
04722 Neurotrophin signaling pathway
113251972 (GSK3B)
09158 Development and regeneration
04360 Axon guidance
113251972 (GSK3B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113251972 (GSK3B)
09162 Cancer: specific types
05210 Colorectal cancer
113251972 (GSK3B)
05225 Hepatocellular carcinoma
113251972 (GSK3B)
05226 Gastric cancer
113251972 (GSK3B)
05217 Basal cell carcinoma
113251972 (GSK3B)
05215 Prostate cancer
113251972 (GSK3B)
05213 Endometrial cancer
113251972 (GSK3B)
05224 Breast cancer
113251972 (GSK3B)
09172 Infectious disease: viral
05160 Hepatitis C
113251972 (GSK3B)
05162 Measles
113251972 (GSK3B)
05163 Human cytomegalovirus infection
113251972 (GSK3B)
05167 Kaposi sarcoma-associated herpesvirus infection
113251972 (GSK3B)
05165 Human papillomavirus infection
113251972 (GSK3B)
09171 Infectious disease: bacterial
05135 Yersinia infection
113251972 (GSK3B)
09164 Neurodegenerative disease
05010 Alzheimer disease
113251972 (GSK3B)
05020 Prion disease
113251972 (GSK3B)
05022 Pathways of neurodegeneration - multiple diseases
113251972 (GSK3B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113251972 (GSK3B)
05415 Diabetic cardiomyopathy
113251972 (GSK3B)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
113251972 (GSK3B)
04932 Non-alcoholic fatty liver disease
113251972 (GSK3B)
04931 Insulin resistance
113251972 (GSK3B)
04934 Cushing syndrome
113251972 (GSK3B)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113251972 (GSK3B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113251972 (GSK3B)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uah03036
]
113251972 (GSK3B)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.26 tau-protein kinase
113251972 (GSK3B)
Protein kinases [BR:
uah01001
]
Serine/threonine kinases: CMGC group
GSK family [OT]
113251972 (GSK3B)
Chromosome and associated proteins [BR:
uah03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
113251972 (GSK3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kinase-like
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
113251972
NCBI-ProteinID:
XP_026350005
LinkDB
All DBs
Position
Unknown
AA seq
436 aa
AA seq
DB search
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASGPLRCLTWW
QLVFPGPTDPRKRTRC
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgaccacagtg
gtggcaactcctgggcagggtccagataggccacaagaagtcagctatacagacactaaa
gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggttgccatcaagaaagtattacaggacaagagatttaagaaccgagagctccaaatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatatgccaccgg
gatattaaaccacagaacctcttgttggatcctgatacagctgtcttaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctccagtatagatgta
tggtctgcaggctgtgtgttggctgagctgttactaggacaaccaatatttccaggggac
agtggtgtggatcaattggtggaaataatcaaggtcctggggacaccaacaagggagcaa
attagagaaatgaaccccaactacacagaattcaaattccctcaaattaaggcacatcct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cggacgccaccggaggcaattgcactgtgtagccgtctgctggagtatacaccaactgcc
cgattgacaccactggaagcttgtgcacattcattttttgatgaattaagggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctagctaccatccttattcctcctcatgctcggattcaagcagct
gcttcaacccctacaaatgccacagcagcctcagggccacttaggtgtctcacatggtgg
cagctggttttccctggaccaactgatccaagaaagaggacaagatgctaa
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